+C Two-component system KO
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Two-Component System - Staphylococcus aureus subsp. aureus CN1 (CA-MRSA)
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C SAKOR_01632 Phosphate regulon sensor protein phoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C SAKOR_01633 Alkaline phosphatase synthesis two-component response regulator phoP K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C SAKOR_02044 Sensor protein kdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C SAKOR_02045 Two-component response regulator kdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
C SAKOR_01435 Sensor protein SrrB K07651 resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]
C SAKOR_01436 Transcriptional regulatory protein resD K07775 resD; two-component system, OmpR family, response regulator ResD
B VicK-VicR (cell wall metabolism)
C SAKOR_00019 Two-component sensor kinase VicK/WalK K07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]
C SAKOR_00018 Two-component response regulator VicR/WalR K07668 vicR; two-component system, OmpR family, response regulator VicR
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
C SAKOR_00702 Sensory transduction protein kinase SaeS K10681 saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]
C SAKOR_00703 Two-component response regulator SaeR K10682 saeR; two-component system, OmpR family, response regulator SaeR
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
C SAKOR_02622 Two-component sensor histidine kinase K19081 braS; two-component system, OmpR family, sensor histidine kinase BraS/BceS [EC:2.7.13.3]
C SAKOR_02623 Two-component response regulator K19082 braR; two-component system, OmpR family, response regulator protein BraR/BceR
B GraS-GraR (cationic antimicrobial peptide transport)
C SAKOR_00655 Sensor histidine kinase GraS/ApsS K19077 graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3]
C SAKOR_00654 Response regulator GraR/ApsR K19078 graR; two-component system, OmpR family, response regulator protein GraR
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
C SAKOR_01351 Two-component sensor kinase arlS K18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]
C SAKOR_01352 Two-component response regulator arlR K18941 arlR; two-component system, OmpR family, response regulator ArlR
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C SAKOR_02338 Two component system histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C SAKOR_02337 Two-component response regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
C SAKOR_01256 Sensory Transduction Histidine Kinase K07778 desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]
C SAKOR_01257 Two-component response regulator K07693 desR; two-component system, NarL family, response regulator DesR
B VraS-VraR (cell-wall peptidoglycan synthesis)
C SAKOR_01841 Two-component sensor protein VraS K07681 vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3]
C SAKOR_01840 Two-component response regulator VraR K07694 vraR; two-component system, NarL family, vancomycin resistance associated response regulator VraR
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
C SAKOR_02370 Two component system histidine kinase K07683 nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]
C SAKOR_02369 Two-component response regulator K07696 nreC; two-component system, NarL family, response regulator NreC
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
C SAKOR_01805 Two-component sensor protein yhcY K02480 K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]
C SAKOR_01804 hypothetical protein K02479 K02479; two-component system, NarL family, response regulator
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
C SAKOR_00239 Autolysin sensor kinase LytS K07704 lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]
C SAKOR_00240 Autolysin response regulator LytR K07705 lytT; two-component system, LytTR family, response regulator LytT
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
C SAKOR_02002 Sensory transduction histidine kinase AgrC K07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]
C SAKOR_02003 Accessory gene regulator protein A AGRA K07707 agrA; two-component system, LytTR family, response regulator AgrA
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B BtsS-BtsR (pyruvate reutilization)
B PyrS-PyrR (pyruvate reutilization)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
C SAKOR_00197 Two-component sensor kinase yesM K25212 hptS; two-component system, sensor histidine kinase HptS [EC:2.7.13.3]
C SAKOR_00196 Two-component response regulator yesN K25213 hptR; two-component system, response regulator HptR
B YesM-YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 8, 2024