+F Repair protein KO
#
DNA Repair and Recombination Proteins - Stomoxys calcitrans (stable fly)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 106081099 activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 106080972 deoxyribodipyrimidine photo-lyase isoform X1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 106080596 single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 106082626 N-glycosylase/DNA lyase isoform X1 K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E 106083395 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
F 106089977 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 106087498 DNA polymerase delta small subunit K02328 POLD2; DNA polymerase delta subunit 2
F 106085836 uncharacterized protein DDB_G0286299 K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F 106085578 DNA polymerase epsilon catalytic subunit A isoform X1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 106090797 DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 106094131 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 106080913 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 106081394 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 106087297 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E 106086392 DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
E 106083111 DNA ligase 3 K10776 LIG3; DNA ligase 3 [EC:6.5.1.1]
D Other BER factors
E 106082439 probable tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 106087202 aprataxin-like protein isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 106085581 uncharacterized protein F21D5.5 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 106082152 high mobility group protein DSP1 K10802 HMGB1; high mobility group protein B1
E 106090270 poly [ADP-ribose] polymerase K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 106085040 DNA repair protein complementing XP-C cells homolog isoform X1 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 106082003 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
F 106082005 UV excision repair protein RAD23 homolog A-like K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F 106096045 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 106091878 cullin-4A K10609 CUL4; cullin 4
F 106089454 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 106080855 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 106096251 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 106080900 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 106080396 transcriptional adapter 2A isoform X1 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 106083854 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 106085813 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 106089240 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 106096153 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 106092845 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 106084507 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 106095557 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 106082351 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 106096045 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 106091878 cullin-4A K10609 CUL4; cullin 4
F 106089454 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F 106094238 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 106087387 DNA excision repair protein haywire K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 106082338 TFIIH basal transcription factor complex helicase XPD subunit K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 106082641 general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 106089785 general transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 106087656 general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 106094045 general transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 106082302 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 106087544 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 106080699 CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 106088734 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 106080585 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 106089162 uncharacterized protein LOC106089162 K10740 RPA3; replication factor A3
D Other NER factors
E 106086685 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 106087642 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 106091920 DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 106094214 DNA repair protein complementing XP-G cells isoform X1 K10846 ERCC5; DNA excision repair protein ERCC-5
E 106081443 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 106095486 cullin-3-like K03869 CUL3; cullin 3
E 106081111 cullin-3-like K03869 CUL3; cullin 3
E 106081651 cullin-5 K10612 CUL5; cullin 5
E 106087309 transcription elongation factor B polypeptide 1 K03872 ELOC; elongin-C
E 106090867 transcription elongation factor B polypeptide 2 K03873 ELOB; elongin-B
E 106082802 transcription elongation factor B polypeptide 3 K15076 ELOA; elongin-A
E 106091704 protein lingerer isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 106082040 DNA mismatch repair protein spellchecker 1-like K08735 MSH2; DNA mismatch repair protein MSH2
E 106092423 DNA mismatch repair protein spellchecker 1 K08735 MSH2; DNA mismatch repair protein MSH2
E 106095142 probable DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 106090131 DNA mismatch repair protein Mlh1 isoform X1 K08734 MLH1; DNA mismatch repair protein MLH1
E 106081916 mismatch repair endonuclease PMS2 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E 106089977 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 106087498 DNA polymerase delta small subunit K02328 POLD2; DNA polymerase delta subunit 2
E 106085836 uncharacterized protein DDB_G0286299 K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E 106088734 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 106080585 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 106089162 uncharacterized protein LOC106089162 K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 106095617 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E 106085540 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 106088976 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E 106083851 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
E 106086886 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 106081394 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 106090331 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 106082152 high mobility group protein DSP1 K10802 HMGB1; high mobility group protein B1
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 106083948 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 106091600 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 106090916 nibrin K10867 NBN; nibrin
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
E 106085111 DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 106083948 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 106091600 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 106090916 nibrin K10867 NBN; nibrin
D BRCA complex
E 106086735 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 106086735 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 106096362 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 106082321 DNA repair protein RAD51 homolog 4 K10871 RAD51L3; RAD51-like protein 3
E 106086410 DNA repair protein XRCC3 isoform X1 K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E 106086325 DNA repair and recombination protein RAD54-like isoform X1 K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 106083436 helicase ARIP4 K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]
D RecQ family DNA helicases
E 106086389 Werner syndrome ATP-dependent helicase-like K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 106088667 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 106091083 uncharacterized protein LOC106091083 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 106089150 ATP-dependent DNA helicase Q5 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 106088667 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 106083365 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 106087111 DNA topoisomerase 3-beta K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D RPA (replication factor A)
E 106088734 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 106080585 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 106089162 uncharacterized protein LOC106089162 K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 106084292 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 106084221 serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 106095794 serine/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E 106091973 structural maintenance of chromosomes protein 5-like K22803 SMC5; structural maintenance of chromosomes protein 5
E 106087659 structural maintenance of chromosomes protein 6 K22804 SMC6; structural maintenance of chromosomes protein 6
E 106089205 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 106083585 melanoma-associated antigen D2 K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 106088802 EP300-interacting inhibitor of differentiation 3 K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E 106081028 uncharacterized protein LOC106081028 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 106081622 exonuclease 3'-5' domain-containing protein 2 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 106092785 crossover junction endonuclease MUS81 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 106093625 DNA repair protein SWI5 homolog K10991 SWI5; DNA repair protein Swi5/Sae3
E 106094679 structure-specific endonuclease subunit SLX1 homolog K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 106082371 flap endonuclease GEN K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 106084269 uncharacterized protein LOC106084269 K19026 SPG11; spatacsin
E 106080412 zinc finger FYVE domain-containing protein 26 homolog K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 106095604 nuA4 complex subunit EAF3 homolog K11339 MORF4L1; mortality factor 4-like protein 1
E 106094231 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 isoform X1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 106085855 fidgetin-like protein 1 isoform X1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 106086048 uncharacterized protein LOC106086048 K23112 BRAT1; BRCA1-associated ATM activator 1
E 106087168 myosin-G heavy chain isoform X1 K23456 CFAP410; cilla- and flagella-associated protein
E 106084053 serine-rich adhesin for platelets isoform X1 K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 106087909 protein MMS22-like K26125 MMS22L; protein MMS22-like
E 106087786 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 106092201 Werner Syndrome-like exonuclease K22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 106088232 ATP-dependent DNA helicase 2 subunit 1 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 106092749 X-ray repair cross-complementing protein 5 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
D MRX complex
E 106083948 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 106091600 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 106085900 DNA ligase 4 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
D Other NHEJ factors
E 106087202 aprataxin-like protein isoform X1 K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
C FA (Fanconi anemia) pathway
D FA core complex
E 106090856 E3 ubiquitin-protein ligase FANCL K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 106083252 uncharacterized protein LOC106083252 K10896 FANCM; fanconi anemia group M protein
D FA core complex binding factors
E 106086185 transcription factor HES-1-like K06054 HES1; hairy and enhancer of split 1
E 106087724 ubiquitin-conjugating enzyme E2 D2B-like K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E 106088667 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 106083365 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 106087111 DNA topoisomerase 3-beta K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
D FANCD2-I complex
E 106082973 Fanconi anemia group D2 protein K10891 FANCD2; fanconi anemia group D2 protein
E 106080710 Fanconi anemia group I protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
D Other FA pathway factors
E 106086735 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 106096362 DNA repair protein RAD51 homolog 3 K10870 RAD51L2; RAD51-like protein 2
E 106092896 ubiquitin carboxyl-terminal hydrolase 1 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 106092990 WD repeat-containing protein 48 homolog isoform X1 K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 106085223 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 106089050 serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
D Ubiquitin ligases
E 106085523 probable E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 106094683 telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1
E 106080836 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 106090745 DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 106095803 DNA polymerase iota isoform X1 K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 106092125 DNA repair protein REV1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 106086681 DNA polymerase zeta catalytic subunit K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D 106084799 ubiquitin-conjugating enzyme E2-17 kDa K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 106090484 ubiquitin-conjugating enzyme E2 variant 1 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 106085301 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 106081394 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 106085032 uncharacterized protein LOC106085032 K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 106086931 uncharacterized protein LOC106086931 K26957 GCNA; germ cell nuclear acidic protein
B Check point factors
C Rad9-Hus1-Rad1 complex
D 106090207 cell cycle checkpoint control protein RAD9A K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 106090268 checkpoint protein HUS1 isoform X1 K10903 HUS1; HUS1 checkpoint protein
D 106084986 cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 106086893 cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D 106085540 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 106088976 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 106083851 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D 106086886 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 106084986 cell cycle checkpoint protein RAD1 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 106082285 protein timeless homolog K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 106092079 protein TIPIN homolog K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 106094777 claspin homolog K25773 CLSPN; claspin
C Triple T complex
D 106085574 TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D 106082518 large proline-rich protein bag6-A isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 106091006 ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4
D 106087180 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 106089666 serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 106086305 serine/threonine-protein kinase ATM isoform X1 K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 106082767 serine/threonine-protein kinase grp K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 106083079 ovarian-specific serine/threonine-protein kinase Lok isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 106080611 M-phase inducer phosphatase isoform X1 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 106085393 14-3-3 protein zeta K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 106095380 14-3-3 protein zeta-like K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 106089236 14-3-3 protein epsilon K06630 YWHAE; 14-3-3 protein epsilon
D 106088247 protein sickie isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 106083542 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 106082624 period circadian protein isoform X1 K02633 PER2; period circadian protein 2
D 106093554 LOW QUALITY PROTEIN: uncharacterized protein LOC106093554 K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 106095892 plastin-3 K17336 PLS3; plastin-3
D 106085809 protein downstream neighbor of son homolog isoform X1 K22422 DONSON; protein downstream neighbor of Son
D 106083656 uncharacterized protein LOC106083656 isoform X1 K22808 KANK; KN motif and ankyrin repeat domain-containing protein
D 106088796 vacuolar protein sorting-associated protein 4A K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 106086813 abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 106089313 protein SDE2 homolog K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 106083095 DNA polymerase theta-like K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 106093117 myb-binding protein 1A-like protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D 106082054 uncharacterized protein LOC106082054 isoform X1 K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D 106086324 uncharacterized protein LOC106086324 K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D 106088477 three prime repair exonuclease 2-like K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D 106085850 uncharacterized protein LOC106085850 K15340 DCLRE1A; DNA cross-link repair 1A protein
D 106085541 uncharacterized protein LOC106085541 isoform X1 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D 106086472 helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
C PSO4 complex
D 106092806 pre-mRNA-processing factor 19 isoform X1 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 106086628 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 106095014 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 106095341 pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 106081600 8-oxo-dGDP phosphatase NUDT18 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 106085852 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 106087103 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 106091606 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 106085380 ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 106080972 deoxyribodipyrimidine photo-lyase isoform X1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 106080596 single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 106083395 endonuclease III-like protein 1 isoform X1 K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 106081589 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 106081589 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 106085852 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 106087103 deoxyuridine 5'-triphosphate nucleotidohydrolase-like K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024