+F Repair protein KO
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DNA Repair and Recombination Proteins - Salmonella enterica subsp. enterica serovar Gallinarum/pullorum RKS5078
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPUL_1479 ogt; O6-methylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SPUL_2253 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SPUL_0278 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPUL_3113 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPUL_1268 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SPUL_0145 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPUL_3833 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPUL_1479 ogt; O6-methylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SPUL_0626 ada; ADA regulatory protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SPUL_2253 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SPUL_0278 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPUL_3225 mug; G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E SPUL_0770 alkA; DNA-3-methyladenine glycosidase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SPUL_3113 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPUL_3925 tag; 3-methyladenine DNA glycosylase I, constitutive K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SPUL_3838 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SPUL_2246 nei; endonuclease VIII, DNA N-glycosylase with an AP lyase activity K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E SPUL_1268 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SPUL_1116 xthA; exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E SPUL_0683 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E SPUL_3416 nfi; putative endonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E SPUL_3041 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SPUL_0455 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SPUL_3825 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SPUL_3671 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SPUL_4245 uvrA; excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
E SPUL_2177 uvrB; excision nuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E SPUL_1833 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E SPUL_1125 hypothetical protein K05984 cho; excinuclease Cho [EC:3.1.25.-]
E SPUL_3481 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPUL_3671 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SPUL_0455 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SPUL_3825 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SPUL_3433 rpoB; DNA-directed RNA polymerase, beta-subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SPUL_3432 rpoC; DNA-directed RNA polymerase, beta'-subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SPUL_4167 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SPUL_3822 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SPUL_1017 mfd; transcription-repair coupling factor (TrcF) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SPUL_2907 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E SPUL_0831 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SPUL_0368 xseA; exonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SPUL_2543 xseB; exodeoxyribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E SPUL_1762 exoX; exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E SPUL_0251 dnaE; DNA polymerase III, alpha chain K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SPUL_3729 dnaN; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SPUL_4453 holC; DNA polymerase III, chi subunit K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E SPUL_2314 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SPUL_1002 holB; DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SPUL_2718 dnaQ; DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SPUL_2479 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E SPUL_4547 ribosomal-protein-alanine acetyltransferase K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E SPUL_1760 holE; DNA polymerase III, theta subunit K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E SPUL_0455 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SPUL_3825 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SPUL_3481 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPUL_4246 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SPUL_4097 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E SPUL_1878 vsr; patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SPUL_3002 recB; exonuclease V subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E SPUL_3004 recC; exonuclease V subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E SPUL_3001 recD; exonuclease V alpha-subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SPUL_2823 recA; recombinase A K03553 recA; recombination protein RecA
E SPUL_1779 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SPUL_1778 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SPUL_1782 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SPUL_3567 priA; primosomal protein replication factor K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SPUL_4382 priB; primosomal replication protein N K02686 priB; primosomal replication protein N
E SPUL_2482 priC; primosomal replication protein N K04067 priC; primosomal replication protein N''
E SPUL_4536 dnaT; primosomal protein I K02317 dnaT; DNA replication protein DnaT
E SPUL_0831 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SPUL_2576 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SPUL_2575 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SPUL_2823 recA; recombinase A K03553 recA; recombination protein RecA
E SPUL_4567 radA; putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E SPUL_3730 recF; recF protein K03629 recF; DNA replication and repair protein RecF
E SPUL_3819 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SPUL_3041 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SPUL_0294 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
E SPUL_2477 recR; recombination protein RecR K06187 recR; recombination protein RecR
E SPUL_2749 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E SPUL_2579 rdgC; recombination associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E SPUL_1779 ruvA; Holliday junction DNA helicase K03550 ruvA; holliday junction DNA helicase RuvA
E SPUL_1778 ruvB; Holliday junction DNA helicase K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SPUL_1782 ruvC; crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E SPUL_2937 hypothetical protein K15342 cas1; CRISP-associated protein Cas1
E SPUL_0662 yejH; putative helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E SPUL_2576 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SPUL_2575 sbcD; exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SPUL_0619 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SPUL_3731 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SPUL_1528 topA; DNA topoisomerase I, omega protein I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SPUL_3414 hupA; histone like DNA-binding protein HU-alpha (NS2) (HU-2) K05787 hupA; DNA-binding protein HU-alpha
F SPUL_2514 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SPUL_1752 Exodeoxyribonuclease VIII K10906 recE; exodeoxyribonuclease VIII [EC:3.1.11.-]
F SPUL_1753 recT; phage recombination protein K07455 recT; recombination protein RecT
F SPUL_3041 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SPUL_0294 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
F SPUL_2477 recR; recombination protein RecR K06187 recR; recombination protein RecR
F SPUL_0455 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F SPUL_3825 yicF; putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SPUL_3395 fis; Fis DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F SPUL_1155 himA; Integration host factor alpha-subunit K04764 ihfA; integration host factor subunit alpha
F SPUL_2025 himD; integration host factor beta-subunit (IHF-beta) K05788 ihfB; integration host factor subunit beta
E Supressor
F SPUL_0831 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F SPUL_3474 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SPUL_4245 uvrA; excision nuclease subunit A K03701 uvrA; excinuclease ABC subunit A
F SPUL_2177 uvrB; excision nuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F SPUL_0903 putative DNA-binding protein (histone-like protein hlp-II) K03746 hns; DNA-binding protein H-NS
F SPUL_1565 hns; H-ns protein (histone-like protein Hlp-II) K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SPUL_2660 dinP; hypothetical protein DinP (DNA damage-inducible protein) K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D SPUL_2823 recA; recombinase A K03553 recA; recombination protein RecA
D SPUL_4227 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SPUL_2749 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SPUL_4246 ssb; single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPUL_0962 dinI; damage-inducible protein K12149 dinI; DNA-damage-inducible protein I
D SPUL_2822 putative regulatory protein K03565 recX; regulatory protein
D SPUL_4071 hypothetical protein K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SPUL_3513 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D SPUL_1980 helD; helicase IV (75 kD helicase) K03658 helD; DNA helicase IV [EC:5.6.2.4]
D SPUL_1638 yoaA; putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SPUL_0145 mutT; 7,8-dihydro-8-oxoguanine-triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPUL_3833 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SPUL_0614 nrdA; ribonucleoside-diphosphate reductase 1 alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPUL_2804 nrdE; ribonucleoside-diphosphate reductase 2 alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPUL_0613 nrdB; ribonucleoside-diphosphate reductase 1 beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SPUL_2805 nrdF; ribonucleoside-diphosphate reductase 2 beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025