+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Seonamhaeicola sp. S2-3</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    BWZ22_15645 subtype II CRISPR-associated endonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    BWZ22_15640 CRISPR-associated endonuclease Cas2	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
D      BWZ22_15650 hypothetical protein	K09952 csn1; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-] 
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    BWZ22_03075 restriction endonuclease subunit R	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    BWZ22_03065 hypothetical protein	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      BWZ22_13280 DNA methyltransferase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
D      BWZ22_01055 DNA (cytosine-5-)-methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      BWZ22_08135 DNA (cytosine-5-)-methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      BWZ22_08200 DNA (cytosine-5-)-methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      BWZ22_08805 DNA (cytosine-5-)-methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      BWZ22_13380 hypothetical protein	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
D      BWZ22_15360 DNA (cytosine-5-)-methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
C    BWZ22_15295 hypothetical protein	K01156 res; type III restriction enzyme [EC:3.1.21.5] 
B  Type IV R-M system
C    BWZ22_03060 hypothetical protein	K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-] 
C    BWZ22_03055 restriction endonuclease	K19147 mcrC; 5-methylcytosine-specific restriction enzyme subunit McrC 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      BWZ22_11330 plasmid stabilization protein	K19092 parE1_3_4; toxin ParE1/3/4 
D      BWZ22_11335 CopG family transcriptional regulator	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
C    HigB-HigA
D      BWZ22_05115 addiction module toxin RelE	K19166 higB; mRNA interferase HigB [EC:3.1.-.-] 
D      BWZ22_03045 XRE family transcriptional regulator	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
D      BWZ22_05110 transcriptional regulator	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    SpoIISA-SpoIISB
C    Tse6-Tsi6
C    Type II TA system related factors
D      BWZ22_02625 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      BWZ22_03275 rod shape-determining protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      BWZ22_00385 DNA topoisomerase IV	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      BWZ22_00390 DNA topoisomerase IV	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      BWZ22_06870 glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
C    AbiEii-AbiEi
B  Type V TA system
C    GhoT-GhoS
C    Other GhoT/OrtT toxin family protein
B  Type VI TA system
C    SocB-SocA
B  Type VII TA system
C    Hha-TomB
C    TglT-TakA
C    HepT-MntA
B  Type VIII TA system
C    SdsR-RyeA
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    BWZ22_12495 cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: May 19, 2025