+F Repair protein KO
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DNA Repair and Recombination Proteins - Serratia sp. SCBI
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SERRSCBI_12100 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SERRSCBI_05745 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SERRSCBI_18420 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SERRSCBI_20155 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SERRSCBI_10650 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SERRSCBI_00105 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_03485 nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_06660 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_16075 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_23150 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SERRSCBI_12100 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SERRSCBI_04365 bifunctional regulatory protein/DNA repair protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SERRSCBI_05745 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SERRSCBI_18420 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SERRSCBI_20545 G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E SERRSCBI_17775 AraC family transcriptional regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SERRSCBI_20155 adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SERRSCBI_00300 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SERRSCBI_23125 formamidopyrimidine/5-formyluracil/5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SERRSCBI_05790 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E SERRSCBI_10650 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SERRSCBI_12810 exonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E SERRSCBI_16055 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E SERRSCBI_01330 endonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E SERRSCBI_19440 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SERRSCBI_17275 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SERRSCBI_23310 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SERRSCBI_21285 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E SERRSCBI_06065 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E SERRSCBI_08660 uvrC; excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E SERRSCBI_08730 nucleotide excision repair endonuclease K05984 cho; excinuclease Cho [EC:3.1.25.-]
E SERRSCBI_00825 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SERRSCBI_23310 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SERRSCBI_17275 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SERRSCBI_01255 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SERRSCBI_01260 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SERRSCBI_21670 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SERRSCBI_23200 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SERRSCBI_09470 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SERRSCBI_03770 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E SERRSCBI_01685 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E SERRSCBI_19115 DNA mismatch repair protein K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E SERRSCBI_15975 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SERRSCBI_18025 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SERRSCBI_04725 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E SERRSCBI_09140 exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E SERRSCBI_18850 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SERRSCBI_00165 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SERRSCBI_02300 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E SERRSCBI_05530 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SERRSCBI_08995 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SERRSCBI_04010 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SERRSCBI_05080 DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E SERRSCBI_02895 DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E SERRSCBI_09160 DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E SERRSCBI_14150 DNA polymerase II subunit beta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
E SERRSCBI_15970 DNA polymerase II subunit beta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E SERRSCBI_17275 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SERRSCBI_00825 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SERRSCBI_14095 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E SERRSCBI_21280 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SERRSCBI_22035 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SERRSCBI_19055 recB; exonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E SERRSCBI_19050 recD; exonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SERRSCBI_03835 recA; recombinase A K03553 recA; recombination protein RecA
E SERRSCBI_23636 recA; recombinase A K03553 recA; recombination protein RecA
E SERRSCBI_13130 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SERRSCBI_13125 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SERRSCBI_13135 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SERRSCBI_22870 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SERRSCBI_01780 primosomal replication protein N K02686 priB; primosomal replication protein N
E SERRSCBI_05065 primosomal replication protein n'' K04067 priC; primosomal replication protein N''
E SERRSCBI_15975 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E SERRSCBI_04575 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SERRSCBI_04580 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SERRSCBI_03835 recA; recombinase A K03553 recA; recombination protein RecA
E SERRSCBI_23636 recA; recombinase A K03553 recA; recombination protein RecA
E SERRSCBI_02970 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E SERRSCBI_00170 recF; recombination protein F K03629 recF; DNA replication and repair protein RecF
E SERRSCBI_23215 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SERRSCBI_19440 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SERRSCBI_18340 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E SERRSCBI_05090 recombination protein RecR K06187 recR; recombination protein RecR
E SERRSCBI_18435 recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E SERRSCBI_04550 rdgC; recombination associated protein K03554 rdgC; recombination associated protein RdgC
E SERRSCBI_13130 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SERRSCBI_13125 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SERRSCBI_13135 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E SERRSCBI_16180 type III restriction protein res subunit K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E SERRSCBI_04575 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SERRSCBI_04580 exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E SERRSCBI_21950 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SERRSCBI_16375 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SERRSCBI_00175 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SERRSCBI_12515 DNA topoisomerase I subunit omega K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SERRSCBI_01340 transcriptional regulator HU subunit alpha K05787 hupA; DNA-binding protein HU-alpha
F SERRSCBI_04815 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SERRSCBI_19440 ssDNA exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SERRSCBI_18340 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F SERRSCBI_05090 recombination protein RecR K06187 recR; recombination protein RecR
F SERRSCBI_17275 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SERRSCBI_21185 fis; global DNA-binding transcriptional dual regulator Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F SERRSCBI_10210 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F SERRSCBI_08145 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F SERRSCBI_15975 sbcB; exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F SERRSCBI_00850 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SERRSCBI_21285 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F SERRSCBI_06065 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
F SERRSCBI_12765 histone family protein nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SERRSCBI_04240 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SERRSCBI_14660 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D SERRSCBI_23646 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D SERRSCBI_14665 DNA polymerase V subunit UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D SERRSCBI_23641 DNA polymerase V subunit UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D SERRSCBI_03835 recA; recombinase A K03553 recA; recombination protein RecA
D SERRSCBI_23636 recA; recombinase A K03553 recA; recombination protein RecA
D SERRSCBI_21385 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SERRSCBI_18435 recombination and repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SERRSCBI_03280 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D SERRSCBI_14095 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D SERRSCBI_21280 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SERRSCBI_08910 DNA damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D SERRSCBI_03840 recX; recombination regulator RecX K03565 recX; regulatory protein
D SERRSCBI_23906 putative transposase YhgA family protein K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SERRSCBI_00680 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D SERRSCBI_08395 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D SERRSCBI_06835 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D SERRSCBI_13055 helicase c2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SERRSCBI_00105 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_03485 nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_06660 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_16075 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SERRSCBI_23150 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SERRSCBI_16385 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SERRSCBI_18605 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SERRSCBI_16390 nrdB; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SERRSCBI_18610 nrdF; ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025