+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Sinorhizobium fredii USDA 257</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    USDA257_c02030 putative type I restriction enzyme hindVIIP R protein	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    USDA257_c02040 type-1 restriction enzyme MjaXIP specificity protein	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    USDA257_c02050 putative type I restriction enzyme MjaXP M protein	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      USDA257_c06510 smeIM; modification methylase SmeI	K13581 ccrM; modification methylase [EC:2.1.1.72] 
D      USDA257_c39100 ngoMIVM: modification methylase NgoMIV	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
D      USDA257_c28310 putative kinase Y4mE	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
D      USDA257_c24660 plasmid stabilization system	K19092 parE1_3_4; toxin ParE1/3/4 
D      USDA257_c28980 hypothetical protein	K19092 parE1_3_4; toxin ParE1/3/4 
D      USDA257_c28990 putative addiction module antidote protein, family	K07746 parD1_3_4; antitoxin ParD1/3/4 
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      USDA257_c28360 ntrR; NtrR2 PIN domain protein	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      USDA257_c29360 vapC; tRNA(fMet)-specific endonuclease VapC	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      USDA257_c28350 SpoVT/AbrB domain protein	K18829 mvpT; antitoxin VapB 
D      USDA257_c29370 putative virulence-associated protein	K18829 mvpT; antitoxin VapB 
D      USDA257_c10270 PilT protein domain protein	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      USDA257_c20900 vapC30; putative ribonuclease VapC30	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      USDA257_c22750 putative VapC ribonuclease	K19686 vapC; ribonuclease VapC [EC:3.1.-.-] 
D      USDA257_c20890 hypothetical protein	K19687 vapB; antitoxin VapB 
D      USDA257_c22760 hypothetical protein	K19687 vapB; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
D      USDA257_c22430 putative VapC ribonuclease Y4jK	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      USDA257_c16780 putative plasmid stabilization protein	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      USDA257_c24790 Yle	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      USDA257_c28910 PilT protein domain protein	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      USDA257_c22420 putative plasmid stability protein y4jJ	K21495 fitA; antitoxin FitA 
C    BC_0920-BC_0921
C    Type II TA system related factors
D      USDA257_c43660 ftsZ2; cell division protein FtsZ 2	K03531 ftsZ; cell division protein FtsZ 
D      USDA257_c44940 ftsZ1; cell division protein FtsZ 1	K03531 ftsZ; cell division protein FtsZ 
D      USDA257_c09200 parC; DNA topoisomerase 4 subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      USDA257_c34680 gyrB1; DNA gyrase subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      USDA257_c53750 gltX; glutamate--tRNA ligase GltX	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    USDA257_c38000 nifS; cysteine desulfurase NifS	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023