+D GENES KO
#
KEGG Orthology (KO) - Sphingorhabdus sp. SMR4y
%
!
A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:sfla00010]
D SPHFLASMR4Y_00822 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SPHFLASMR4Y_01199 pfp; pyrophosphate--fructose 6-phosphate 1-phosphotransferase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D SPHFLASMR4Y_02885 glpX; fructose 1,6-bisphosphatase K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_01079 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SPHFLASMR4Y_01132 gapA; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D SPHFLASMR4Y_01131 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D SPHFLASMR4Y_01530 gpmA; phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SPHFLASMR4Y_01025 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SPHFLASMR4Y_02219 ttuE; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SPHFLASMR4Y_00930 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D SPHFLASMR4Y_01023 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SPHFLASMR4Y_01022 bfmBAB; 2-oxoisovalerate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SPHFLASMR4Y_00806 pdhC; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_01238 korA; 2-oxoglutarate oxidoreductase subunit KorA K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01237 korB; 2-oxoglutarate oxidoreductase subunit KorB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01385 flhA; S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01400 adhD; putative alcohol dehydrogenase D K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_03374 ahr; aldehyde reductase Ahr K12957 ahr; alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183]
D SPHFLASMR4Y_01953 adhC2; NADP-dependent alcohol dehydrogenase C 2 K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_02846 prpE; propionate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SPHFLASMR4Y_00964 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
C 00020 Citrate cycle (TCA cycle) [PATH:sfla00020]
D SPHFLASMR4Y_01097 gltA; citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D SPHFLASMR4Y_01498 acn; aconitate hydratase A K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D SPHFLASMR4Y_01305 icd; isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D SPHFLASMR4Y_02191 sucA; 2-oxoglutarate dehydrogenase subunit E1 K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D SPHFLASMR4Y_02190 sucB; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_01238 korA; 2-oxoglutarate oxidoreductase subunit KorA K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01237 korB; 2-oxoglutarate oxidoreductase subunit KorB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_02192 sucD; succinate--CoA ligase [ADP-forming] subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SPHFLASMR4Y_02473 sucC; succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SPHFLASMR4Y_00612 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SPHFLASMR4Y_02198 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SPHFLASMR4Y_00610 succinate dehydrogenase/fumarate reductase transmembrane subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SPHFLASMR4Y_00611 succinate dehydrogenase/fumarate reductase transmembrane subunit K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D SPHFLASMR4Y_03396 fumB; fumarate hydratase class I, anaerobic K01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2]
D SPHFLASMR4Y_03084 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D SPHFLASMR4Y_02193 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SPHFLASMR4Y_00964 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D SPHFLASMR4Y_01023 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SPHFLASMR4Y_01022 bfmBAB; 2-oxoisovalerate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SPHFLASMR4Y_00806 pdhC; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:sfla00030]
D SPHFLASMR4Y_00822 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SPHFLASMR4Y_02671 pgl; 6-phosphogluconolactonase K01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]
D SPHFLASMR4Y_01543 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D SPHFLASMR4Y_01133 tktA; transketolase 1 K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D SPHFLASMR4Y_00143 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D SPHFLASMR4Y_01265 ywlF; putative sugar phosphate isomerase YwlF K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D SPHFLASMR4Y_02409 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SPHFLASMR4Y_03063 gnl; gluconolactonase K01053 gnl; gluconolactonase [EC:3.1.1.17]
D SPHFLASMR4Y_01594 ttuD; putative hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_02885 glpX; fructose 1,6-bisphosphatase K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D SPHFLASMR4Y_01199 pfp; pyrophosphate--fructose 6-phosphate 1-phosphotransferase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
C 00040 Pentose and glucuronate interconversions [PATH:sfla00040]
D SPHFLASMR4Y_02444 rkpK; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SPHFLASMR4Y_02018 gtaB; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SPHFLASMR4Y_01543 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:sfla00051]
D SPHFLASMR4Y_00283 manA; mannose-6-phosphate isomerase ManA K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D SPHFLASMR4Y_02253 algC; phosphomannomutase/phosphoglucomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D SPHFLASMR4Y_00282 cpsB; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D SPHFLASMR4Y_01597 gpgP; glucosyl-3-phosphoglycerate/mannosyl-3-phosphoglycerate phosphatase K07026 E3.1.3.70; mannosyl-3-phosphoglycerate phosphatase [EC:3.1.3.70]
D SPHFLASMR4Y_01199 pfp; pyrophosphate--fructose 6-phosphate 1-phosphotransferase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D SPHFLASMR4Y_02885 glpX; fructose 1,6-bisphosphatase K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_01079 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SPHFLASMR4Y_01265 ywlF; putative sugar phosphate isomerase YwlF K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D SPHFLASMR4Y_00969 manX; PTS system mannose-specific EIIAB component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
C 00052 Galactose metabolism [PATH:sfla00052]
D SPHFLASMR4Y_02221 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D SPHFLASMR4Y_02018 gtaB; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SPHFLASMR4Y_01199 pfp; pyrophosphate--fructose 6-phosphate 1-phosphotransferase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
C 00053 Ascorbate and aldarate metabolism [PATH:sfla00053]
D SPHFLASMR4Y_02444 rkpK; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SPHFLASMR4Y_03063 gnl; gluconolactonase K01053 gnl; gluconolactonase [EC:3.1.1.17]
D SPHFLASMR4Y_02443 wbgU; UDP-N-acetylglucosamine 4-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00500 Starch and sucrose metabolism [PATH:sfla00500]
D SPHFLASMR4Y_01595 sucrose phosphorylase K00690 E2.4.1.7; sucrose phosphorylase [EC:2.4.1.7]
D SPHFLASMR4Y_02018 gtaB; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SPHFLASMR4Y_02775 pimB; GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase K16150 K16150; glycogen synthase [EC:2.4.1.11]
D SPHFLASMR4Y_00822 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:sfla00520]
D SPHFLASMR4Y_00065 nagZ; beta-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D SPHFLASMR4Y_00724 nodM; glutamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SPHFLASMR4Y_00635 glmM; phosphoglucosamine mutase K03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]
D SPHFLASMR4Y_00721 glmU; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D SPHFLASMR4Y_01065 phosphotransferase enzyme family protein K07102 amgK; N-acetylmuramate 1-kinase [EC:2.7.1.221]
D SPHFLASMR4Y_01064 hddC; D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase K00992 murU; N-acetyl-alpha-D-muramate 1-phosphate uridylyltransferase [EC:2.7.7.99]
D SPHFLASMR4Y_02494 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SPHFLASMR4Y_00092 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D SPHFLASMR4Y_00280 wecB; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D SPHFLASMR4Y_02426 wbpI; UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D SPHFLASMR4Y_00279 wecC; UDP-N-acetyl-D-mannosamine dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D SPHFLASMR4Y_02429 capD; UDP-glucose 4-epimerase K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-]
D SPHFLASMR4Y_02018 gtaB; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SPHFLASMR4Y_02444 rkpK; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SPHFLASMR4Y_02221 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D SPHFLASMR4Y_02443 wbgU; UDP-N-acetylglucosamine 4-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D SPHFLASMR4Y_00969 manX; PTS system mannose-specific EIIAB component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SPHFLASMR4Y_00822 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SPHFLASMR4Y_00283 manA; mannose-6-phosphate isomerase ManA K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D SPHFLASMR4Y_02253 algC; phosphomannomutase/phosphoglucomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D SPHFLASMR4Y_00282 cpsB; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
C 00620 Pyruvate metabolism [PATH:sfla00620]
D SPHFLASMR4Y_02846 prpE; propionate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SPHFLASMR4Y_01238 korA; 2-oxoglutarate oxidoreductase subunit KorA K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01237 korB; 2-oxoglutarate oxidoreductase subunit KorB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01023 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SPHFLASMR4Y_01022 bfmBAB; 2-oxoisovalerate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SPHFLASMR4Y_00806 pdhC; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02367 bphJ; acetaldehyde dehydrogenase 4 K18366 bphJ; acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]
D SPHFLASMR4Y_01385 flhA; S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01400 adhD; putative alcohol dehydrogenase D K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_03374 ahr; aldehyde reductase Ahr K12957 ahr; alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183]
D SPHFLASMR4Y_01953 adhC2; NADP-dependent alcohol dehydrogenase C 2 K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D SPHFLASMR4Y_02219 ttuE; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SPHFLASMR4Y_00197 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_02642 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D SPHFLASMR4Y_02641 purT; phosphoribosylglycinamide formyltransferase 2 K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D SPHFLASMR4Y_01206 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_00616 lldD; alpha-hydroxy-acid oxidizing enzyme K00101 lldD; L-lactate dehydrogenase (cytochrome) [EC:1.1.2.3]
D SPHFLASMR4Y_03206 gloA; lactoylglutathione lyase K01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]
D SPHFLASMR4Y_00113 blh; beta-lactamase hydrolase-like protein K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D SPHFLASMR4Y_03208 gloB; hydroxyacylglutathione hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D SPHFLASMR4Y_02779 putative metallo-hydrolase K01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]
D SPHFLASMR4Y_01578 tme; NADP-dependent malic enzyme K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D SPHFLASMR4Y_02193 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SPHFLASMR4Y_03396 fumB; fumarate hydratase class I, anaerobic K01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2]
D SPHFLASMR4Y_03084 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D SPHFLASMR4Y_01857 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SPHFLASMR4Y_00964 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D SPHFLASMR4Y_00930 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D SPHFLASMR4Y_01344 glcB; malate synthase G K01638 aceB; malate synthase [EC:2.3.3.9]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00914 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:sfla00630]
D SPHFLASMR4Y_00498 isocitrate lyase K01637 E4.1.3.1; isocitrate lyase [EC:4.1.3.1]
D SPHFLASMR4Y_02846 prpE; propionate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SPHFLASMR4Y_01344 glcB; malate synthase G K01638 aceB; malate synthase [EC:2.3.3.9]
D SPHFLASMR4Y_02193 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SPHFLASMR4Y_01097 gltA; citrate (Si)-synthase K01647 CS; citrate synthase [EC:2.3.3.1]
D SPHFLASMR4Y_01498 acn; aconitate hydratase A K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00818 cetB; 2-epi-5-epi-valiolone epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SPHFLASMR4Y_00814 accA1; acetyl-/propionyl-coenzyme A carboxylase alpha chain K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D SPHFLASMR4Y_00820 pccB; propionyl-CoA carboxylase beta chain K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
D SPHFLASMR4Y_00816 scpA; methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D SPHFLASMR4Y_02606 putative FAD-linked oxidoreductase K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D SPHFLASMR4Y_00534 katE; catalase C K03781 katE; catalase [EC:1.11.1.6]
D SPHFLASMR4Y_00671 glycerate dehydrogenase K00015 gyaR; glyoxylate reductase [EC:1.1.1.26]
D SPHFLASMR4Y_01821 ppaX; pyrophosphatase PpaX K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D SPHFLASMR4Y_01516 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SPHFLASMR4Y_01264 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SPHFLASMR4Y_00103 gcvPA; putative glycine dehydrogenase (decarboxylating) subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D SPHFLASMR4Y_00104 gcvPB; putative glycine dehydrogenase (decarboxylating) subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D SPHFLASMR4Y_00101 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00102 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D SPHFLASMR4Y_01594 ttuD; putative hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SPHFLASMR4Y_01386 purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
C 00640 Propanoate metabolism [PATH:sfla00640]
D SPHFLASMR4Y_02846 prpE; propionate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SPHFLASMR4Y_00267 prpE; propionyl-CoA synthetase K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
D SPHFLASMR4Y_01144 bkdA1; 2-oxoisovalerate dehydrogenase subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D SPHFLASMR4Y_01143 bkdA2; 2-oxoisovalerate dehydrogenase subunit beta K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D SPHFLASMR4Y_01142 bkdB; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00197 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_02642 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D SPHFLASMR4Y_02641 purT; phosphoribosylglycinamide formyltransferase 2 K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D SPHFLASMR4Y_01206 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_00814 accA1; acetyl-/propionyl-coenzyme A carboxylase alpha chain K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D SPHFLASMR4Y_00820 pccB; propionyl-CoA carboxylase beta chain K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
D SPHFLASMR4Y_00818 cetB; 2-epi-5-epi-valiolone epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SPHFLASMR4Y_00816 scpA; methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D SPHFLASMR4Y_02473 sucC; succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SPHFLASMR4Y_02192 sucD; succinate--CoA ligase [ADP-forming] subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SPHFLASMR4Y_00122 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
C 00650 Butanoate metabolism [PATH:sfla00650]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_01848 hbd; 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D SPHFLASMR4Y_00794 fadB; fatty acid oxidation complex subunit alpha K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_00343 echA8; putative enoyl-CoA hydratase echA8 K01715 crt; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02367 bphJ; acetaldehyde dehydrogenase 4 K18366 bphJ; acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]
D SPHFLASMR4Y_02621 maiA; maleate isomerase K01799 nicE; maleate isomerase [EC:5.2.1.1]
D SPHFLASMR4Y_00612 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SPHFLASMR4Y_02198 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SPHFLASMR4Y_00610 succinate dehydrogenase/fumarate reductase transmembrane subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SPHFLASMR4Y_00611 succinate dehydrogenase/fumarate reductase transmembrane subunit K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D SPHFLASMR4Y_00950 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01378 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_03062 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01238 korA; 2-oxoglutarate oxidoreductase subunit KorA K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01237 korB; 2-oxoglutarate oxidoreductase subunit KorB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_02105 yngG; hydroxymethylglutaryl-CoA lyase YngG K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D SPHFLASMR4Y_02345 ccl; (R)-citramalyl-CoA lyase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D SPHFLASMR4Y_01961 scoA; putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit A K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
D SPHFLASMR4Y_01959 scoB; putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit B K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
D SPHFLASMR4Y_00619 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
D SPHFLASMR4Y_00004 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]
D SPHFLASMR4Y_01383 estB; esterase EstB K18372 acmB; methyl acetate hydrolase [EC:3.1.1.114]
D SPHFLASMR4Y_00911 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00011 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_03061 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_02970 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00912 ilvH; acetolactate synthase isozyme 3 small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D SPHFLASMR4Y_02140 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K03366 butA; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]
C 00660 C5-Branched dibasic acid metabolism [PATH:sfla00660]
D SPHFLASMR4Y_00911 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00011 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_03061 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_02970 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00912 ilvH; acetolactate synthase isozyme 3 small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00297 cat1; succinyl-CoA:coenzyme A transferase K18288 ict-Y; itaconate CoA-transferase [EC:2.8.3.-]
D SPHFLASMR4Y_02473 sucC; succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SPHFLASMR4Y_02192 sucD; succinate--CoA ligase [ADP-forming] subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SPHFLASMR4Y_02130 mch; mesaconyl-CoA hydratase K18290 ich-Y; itaconyl-CoA hydratase [EC:4.2.1.56]
D SPHFLASMR4Y_02129 mcl1; L-malyl-CoA/beta-methylmalyl-CoA lyase K18292 E4.1.3.25; (S)-citramalyl-CoA lyase [EC:4.1.3.25]
D SPHFLASMR4Y_02983 proA; 4-hydroxy-4-methyl-2-oxoglutarate aldolase/4-carboxy-4-hydroxy-2-oxoadipate aldolase K10218 ligK; 4-hydroxy-4-methyl-2-oxoglutarate aldolase [EC:4.1.3.17]
D SPHFLASMR4Y_02107 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_02610 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_03227 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_02106 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_02609 leuD1; 3-isopropylmalate dehydratase small subunit 1 K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_03229 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_01180 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:sfla00562]
D SPHFLASMR4Y_01126 suhB; inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D SPHFLASMR4Y_00462 suhB; fructose-1,6-bisphosphatase/inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D SPHFLASMR4Y_01278 phy; 3-phytase K01083 E3.1.3.8; 3-phytase [EC:3.1.3.8]
D SPHFLASMR4Y_00122 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D SPHFLASMR4Y_01079 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:sfla00190]
D SPHFLASMR4Y_01125 ndhC; NAD(P)H-quinone oxidoreductase subunit 3 K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D SPHFLASMR4Y_01124 nuoB; NADH-quinone oxidoreductase subunit B K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D SPHFLASMR4Y_01123 nqo5; NADH-quinone oxidoreductase chain 5 K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D SPHFLASMR4Y_01121 nuoD; NADH-quinone oxidoreductase subunit D K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D SPHFLASMR4Y_01120 nqo2; NADH-quinone oxidoreductase chain 2 K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D SPHFLASMR4Y_01118 nqo1; NADH-quinone oxidoreductase chain 1 K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D SPHFLASMR4Y_01116 nqo3; NADH-quinone oxidoreductase chain 3 K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D SPHFLASMR4Y_01114 nuoH; NADH-quinone oxidoreductase subunit H K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D SPHFLASMR4Y_01113 nuoI; NADH-quinone oxidoreductase subunit I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D SPHFLASMR4Y_01111 nuoJ; NADH-quinone oxidoreductase subunit J K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D SPHFLASMR4Y_01110 nuoK; NADH-quinone oxidoreductase subunit K K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D SPHFLASMR4Y_01109 nuoL; NADH-quinone oxidoreductase subunit L K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D SPHFLASMR4Y_01108 nuoM; NADH-quinone oxidoreductase subunit M K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D SPHFLASMR4Y_01107 nuoN; NADH-quinone oxidoreductase subunit N K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D SPHFLASMR4Y_00612 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SPHFLASMR4Y_02198 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SPHFLASMR4Y_00610 succinate dehydrogenase/fumarate reductase transmembrane subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SPHFLASMR4Y_00611 succinate dehydrogenase/fumarate reductase transmembrane subunit K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D SPHFLASMR4Y_00742 petA; ubiquinol-cytochrome c reductase iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D SPHFLASMR4Y_00743 petB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D SPHFLASMR4Y_00744 petC; cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D SPHFLASMR4Y_03046 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D SPHFLASMR4Y_03049 ctaE; cytochrome c oxidase subunit 3 K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D SPHFLASMR4Y_03045 ctaD; cytochrome c oxidase subunit 1 K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D SPHFLASMR4Y_03044 ctaC; cytochrome c oxidase subunit 2 K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D SPHFLASMR4Y_03048 ctaG; cytochrome c oxidase assembly protein CtaG K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D SPHFLASMR4Y_02203 ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D SPHFLASMR4Y_00255 peptidase S41 K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
D SPHFLASMR4Y_00254 cytochrome C oxidase, mono-heme subunit/FixO K00405 ccoO; cytochrome c oxidase cbb3-type subunit II
D SPHFLASMR4Y_00253 Cbb3-type cytochrome oxidase component FixQ K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV
D SPHFLASMR4Y_00252 ccoP; Cbb3-type cytochrome c oxidase subunit CcoP K00406 ccoP; cytochrome c oxidase cbb3-type subunit III
D SPHFLASMR4Y_02163 cydA; cytochrome bd-I ubiquinol oxidase subunit 1 K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D SPHFLASMR4Y_02164 appB; cytochrome bd-II ubiquinol oxidase subunit 2 K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D SPHFLASMR4Y_02057 cycM; cytochrome c-552 K08738 CYC; cytochrome c
D SPHFLASMR4Y_02601 cycM; cytochrome c-552 K08738 CYC; cytochrome c
D SPHFLASMR4Y_02332 cytochrome c-550 K08738 CYC; cytochrome c
D SPHFLASMR4Y_02855 cytochrome c2 K08738 CYC; cytochrome c
D SPHFLASMR4Y_00136 fliI; flagellar protein export ATPase FliI K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D SPHFLASMR4Y_00134 fliI; flagellum-specific ATP synthase FliL K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D SPHFLASMR4Y_00135 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D SPHFLASMR4Y_00137 atpH; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D SPHFLASMR4Y_00133 atpC; ATP synthase F0F1 subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D SPHFLASMR4Y_01188 atpB; ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D SPHFLASMR4Y_01185 atpF; ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D SPHFLASMR4Y_01186 atpG; ATP synthase subunit b' K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D SPHFLASMR4Y_01187 atpE; ATP synthase subunit c K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D SPHFLASMR4Y_02477 ppa; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
D SPHFLASMR4Y_01327 ppk; polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:sfla00710]
D SPHFLASMR4Y_01131 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D SPHFLASMR4Y_01132 gapA; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_02885 glpX; fructose 1,6-bisphosphatase K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D SPHFLASMR4Y_01133 tktA; transketolase 1 K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D SPHFLASMR4Y_01265 ywlF; putative sugar phosphate isomerase YwlF K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D SPHFLASMR4Y_01079 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SPHFLASMR4Y_01543 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D SPHFLASMR4Y_00143 tal; transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D SPHFLASMR4Y_01857 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SPHFLASMR4Y_00964 pckA; phosphoenolpyruvate carboxykinase (ATP) K01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]
D SPHFLASMR4Y_00930 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D SPHFLASMR4Y_01578 tme; NADP-dependent malic enzyme K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D SPHFLASMR4Y_02193 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:sfla00720]
D SPHFLASMR4Y_00930 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D SPHFLASMR4Y_01857 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SPHFLASMR4Y_02193 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SPHFLASMR4Y_03396 fumB; fumarate hydratase class I, anaerobic K01676 E4.2.1.2A; fumarate hydratase, class I [EC:4.2.1.2]
D SPHFLASMR4Y_03084 fumC; class II fumarate hydratase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D SPHFLASMR4Y_00612 sdhA; succinate dehydrogenase flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SPHFLASMR4Y_02198 sdhB; succinate dehydrogenase iron-sulfur subunit K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SPHFLASMR4Y_00610 succinate dehydrogenase/fumarate reductase transmembrane subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SPHFLASMR4Y_00611 succinate dehydrogenase/fumarate reductase transmembrane subunit K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D SPHFLASMR4Y_02192 sucD; succinate--CoA ligase [ADP-forming] subunit alpha K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SPHFLASMR4Y_02473 sucC; succinate--CoA ligase subunit beta K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_01238 korA; 2-oxoglutarate oxidoreductase subunit KorA K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01237 korB; 2-oxoglutarate oxidoreductase subunit KorB K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SPHFLASMR4Y_01305 icd; isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D SPHFLASMR4Y_01498 acn; aconitate hydratase A K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D SPHFLASMR4Y_00197 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_02642 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D SPHFLASMR4Y_02641 purT; phosphoribosylglycinamide formyltransferase 2 K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D SPHFLASMR4Y_01206 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_01388 meh; mesaconyl-C(4)-CoA hydratase K09709 meh; 3-methylfumaryl-CoA hydratase [EC:4.2.1.153]
D SPHFLASMR4Y_00818 cetB; 2-epi-5-epi-valiolone epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SPHFLASMR4Y_00816 scpA; methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D SPHFLASMR4Y_01572 folD; bifunctional protein FolD protein K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D SPHFLASMR4Y_03318 metF; 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D SPHFLASMR4Y_02846 prpE; propionate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:sfla00680]
D SPHFLASMR4Y_01385 flhA; S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01400 adhD; putative alcohol dehydrogenase D K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01384 fghA; S-formylglutathione hydrolase K01070 frmB; S-formylglutathione hydrolase [EC:3.1.2.12]
D SPHFLASMR4Y_01264 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SPHFLASMR4Y_01594 ttuD; putative hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SPHFLASMR4Y_01025 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SPHFLASMR4Y_01857 ppc; phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SPHFLASMR4Y_02193 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_02885 glpX; fructose 1,6-bisphosphatase K11532 glpX-SEBP; fructose-1,6-bisphosphatase II / sedoheptulose-1,7-bisphosphatase [EC:3.1.3.11 3.1.3.37]
D SPHFLASMR4Y_01199 pfp; pyrophosphate--fructose 6-phosphate 1-phosphotransferase K21071 pfk; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90]
D SPHFLASMR4Y_02846 prpE; propionate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SPHFLASMR4Y_01530 gpmA; phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SPHFLASMR4Y_02063 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D SPHFLASMR4Y_02062 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D SPHFLASMR4Y_00909 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 00910 Nitrogen metabolism [PATH:sfla00910]
D SPHFLASMR4Y_02540 nrtA; nitrate transport protein NrtA K15576 nrtA; nitrate/nitrite transport system substrate-binding protein
D SPHFLASMR4Y_02541 cmpB; bicarbonate transport system permease protein CmpB K15577 nrtB; nitrate/nitrite transport system permease protein
D SPHFLASMR4Y_02542 glnQ; glutamine ABC transporter ATP-binding protein K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4]
D SPHFLASMR4Y_02546 nasA; nitrate reductase K00372 nasC; assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-]
D SPHFLASMR4Y_02544 nasD; nitrite reductase [NAD(P)H] K26139 nasD; nitrite reductase [NAD(P)H] large subunit [EC:1.7.1.4]
D SPHFLASMR4Y_02545 nasE; assimilatory nitrite reductase [NAD(P)H] small subunit K26138 nasE; nitrite reductase [NAD(P)H] small subunit [EC:1.7.1.4]
D SPHFLASMR4Y_00915 nitronate monooxygenase K00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]
D SPHFLASMR4Y_00429 lldD; alpha-hydroxy-acid oxidizing enzyme K00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]
D SPHFLASMR4Y_02084 gdhB; NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D SPHFLASMR4Y_01413 gdhA; NAD(P)-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D SPHFLASMR4Y_01516 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SPHFLASMR4Y_01471 gltB; ferredoxin-dependent glutamate synthase 1 K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D SPHFLASMR4Y_02531 gltB; glutamate synthase [NADPH] large chain K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D SPHFLASMR4Y_01472 gltD; glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D SPHFLASMR4Y_02533 gltD; glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D SPHFLASMR4Y_00761 cynT; carbonic anhydrase 1 K01673 cynT; carbonic anhydrase [EC:4.2.1.1]
C 00920 Sulfur metabolism [PATH:sfla00920]
D SPHFLASMR4Y_02324 azo1; FMN-dependent NADPH-azoreductase K00299 ssuE; FMN reductase [EC:1.5.1.38]
D SPHFLASMR4Y_00221 tuf; elongation factor Tu K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D SPHFLASMR4Y_00220 cysD; sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D SPHFLASMR4Y_00222 cysQ; 3'-phosphoadenosine 5'-phosphate phosphatase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D SPHFLASMR4Y_00659 cysH; putative phosphoadenosine phosphosulfate reductase K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D SPHFLASMR4Y_00661 sir; sulfite reductase (ferredoxin) K00381 cysI; sulfite reductase (NADPH) hemoprotein beta-component [EC:1.8.1.2]
D SPHFLASMR4Y_02161 fccB; sulfide dehydrogenase [flavocytochrome c] flavoprotein chain K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D SPHFLASMR4Y_01839 sseA; 3-mercaptopyruvate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SPHFLASMR4Y_00708 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D SPHFLASMR4Y_00077 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D SPHFLASMR4Y_01221 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D SPHFLASMR4Y_02686 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D SPHFLASMR4Y_02398 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D SPHFLASMR4Y_01179 metZ; O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]
D SPHFLASMR4Y_02023 dmdC; 3-methylmercaptopropionyl-CoA dehydrogenase K20035 dmdC; 3-(methylsulfanyl)propanoyl-CoA dehydrogenase [EC:1.3.99.41]
D SPHFLASMR4Y_01225 dmdC; 3-methylmercaptopropionyl-CoA dehydrogenase K20035 dmdC; 3-(methylsulfanyl)propanoyl-CoA dehydrogenase [EC:1.3.99.41]
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:sfla00061]
D SPHFLASMR4Y_00197 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha K01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_02642 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase K02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein
D SPHFLASMR4Y_02641 purT; phosphoribosylglycinamide formyltransferase 2 K01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]
D SPHFLASMR4Y_01206 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta K01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]
D SPHFLASMR4Y_00919 acpP; acyl carrier protein K02078 acpP; acyl carrier protein
D SPHFLASMR4Y_01865 acyl carrier protein K02078 acpP; acyl carrier protein
D SPHFLASMR4Y_00991 acyl carrier protein K02078 acpP; acyl carrier protein
D SPHFLASMR4Y_00921 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D SPHFLASMR4Y_02784 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D SPHFLASMR4Y_00918 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D SPHFLASMR4Y_00162 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00920 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02590 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02338 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02352 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02353 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_03135 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02655 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02662 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00609 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_01289 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D SPHFLASMR4Y_02070 fabI; enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D SPHFLASMR4Y_03268 nitronate monooxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D SPHFLASMR4Y_02524 nitronate monooxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D SPHFLASMR4Y_02962 prpE; propionate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00456 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02365 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02372 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_03215 prpE; acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:sfla00071]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_00794 fadB; fatty acid oxidation complex subunit alpha K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
D SPHFLASMR4Y_02664 carC; caffeyl-CoA reductase-Etf complex subunit CarC K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01522 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_00326 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01935 carC; caffeyl-CoA reductase-Etf complex subunit CarC K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_00923 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01387 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01396 carC; caffeyl-CoA reductase-Etf complex subunit CarC K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01399 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_02323 fadE; acyl-CoA dehydrogenase K00255 ACADL; long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8]
D SPHFLASMR4Y_02962 prpE; propionate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00456 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02365 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02372 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_03215 prpE; acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00404 alkB1; alkane 1-monooxygenase 1 K00496 alkB1_2; alkane 1-monooxygenase [EC:1.14.15.3]
D SPHFLASMR4Y_00997 fdr; ferredoxin--NAD(P)(+) reductase fdr K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D SPHFLASMR4Y_01385 flhA; S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01400 adhD; putative alcohol dehydrogenase D K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
D SPHFLASMR4Y_01153 patatin K14674 TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis [PATH:sfla00121]
D SPHFLASMR4Y_02341 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00076 hdhA; 7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159]
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:sfla00561]
D SPHFLASMR4Y_01594 ttuD; putative hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_01953 adhC2; NADP-dependent alcohol dehydrogenase C 2 K13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]
D SPHFLASMR4Y_00745 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D SPHFLASMR4Y_01155 plsB; glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
D SPHFLASMR4Y_02783 plsX; phosphate acyltransferase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D SPHFLASMR4Y_00828 plsY; glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D SPHFLASMR4Y_02391 2-acyl-glycerophospho-ethanolamine acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D SPHFLASMR4Y_02313 dagK; diacylglycerol kinase K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D SPHFLASMR4Y_01154 putative diacylglycerol O-acyltransferase K00635 tgs; diacylglycerol O-acyltransferase / wax synthase [EC:2.3.1.20 2.3.1.75]
D SPHFLASMR4Y_02649 putative diacylglycerol O-acyltransferase K00635 tgs; diacylglycerol O-acyltransferase / wax synthase [EC:2.3.1.20 2.3.1.75]
D SPHFLASMR4Y_01153 patatin K14674 TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
D SPHFLASMR4Y_01152 ytpA; phospholipase YtpA K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
D SPHFLASMR4Y_00452 mgtA; GDP-mannose-dependent alpha-mannosyltransferase K27597 K27597; 1,2-diacylglycerol 3-alpha-glucosyltransferase/glucuronosyltransferase [EC:2.4.1.337 2.4.1.-]
C 00564 Glycerophospholipid metabolism [PATH:sfla00564]
D SPHFLASMR4Y_01772 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+] K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D SPHFLASMR4Y_01150 gpsA2; putative glycerol-3-phosphate dehydrogenase 2 [NAD(P)+] K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D SPHFLASMR4Y_00746 glpD; aerobic glycerol-3-phosphate dehydrogenase K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D SPHFLASMR4Y_01155 plsB; glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
D SPHFLASMR4Y_00828 plsY; glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D SPHFLASMR4Y_02391 2-acyl-glycerophospho-ethanolamine acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D SPHFLASMR4Y_01153 patatin K14674 TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
D SPHFLASMR4Y_02313 dagK; diacylglycerol kinase K07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]
D SPHFLASMR4Y_00056 pldB; lysophospholipase L2 K01048 pldB; lysophospholipase [EC:3.1.1.5]
D SPHFLASMR4Y_01912 glpQ; glycerophosphoryl diester phosphodiesterase K01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]
D SPHFLASMR4Y_03296 type 12 methyltransferase K00570 pmtA; phosphatidylethanolamine/phosphatidyl-N-methylethanolamine N-methyltransferase [EC:2.1.1.17 2.1.1.71]
D SPHFLASMR4Y_01294 cdsA; phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D SPHFLASMR4Y_01303 CDP-alcohol phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D SPHFLASMR4Y_01304 psd; phosphatidylserine decarboxylase proenzyme K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D SPHFLASMR4Y_00704 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K00995 pgsA; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]
D SPHFLASMR4Y_03324 clsB; cardiolipin synthase B K06131 clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]
D SPHFLASMR4Y_03355 S-adenosylmethionine--diacylglycerol 3-amino-3-carboxypropyl transferase K13622 btaA; S-adenosylmethionine-diacylglycerol 3-amino-3-carboxypropyl transferase
D SPHFLASMR4Y_03354 ubiE; bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase K13623 btaB; S-adenosylmethionine-diacylgycerolhomoserine-N-methlytransferase
C 00565 Ether lipid metabolism [PATH:sfla00565]
D SPHFLASMR4Y_01153 patatin K14674 TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism [PATH:sfla00590]
D SPHFLASMR4Y_01153 patatin K14674 TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
D SPHFLASMR4Y_00458 lox; linoleate 9/13-lipoxygenase K19246 loxA; arachidonate 15-lipoxygenase [EC:1.13.11.33]
C 00591 Linoleic acid metabolism
D SPHFLASMR4Y_01153 patatin K14674 TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
C 00592 alpha-Linolenic acid metabolism
D SPHFLASMR4Y_01153 patatin K14674 TGL4; TAG lipase / steryl ester hydrolase / phospholipase A2 / LPA acyltransferase [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
C 01040 Biosynthesis of unsaturated fatty acids [PATH:sfla01040]
D SPHFLASMR4Y_00639 fatty acid desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
D SPHFLASMR4Y_03072 fatty acid desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
D SPHFLASMR4Y_00528 arylesterase K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]
D SPHFLASMR4Y_00792 tesB; acyl-CoA thioesterase 2 K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
D SPHFLASMR4Y_00805 putative acyl-CoA thioester hydrolase K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]
D SPHFLASMR4Y_01491 putative acyl-CoA thioester hydrolase K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:sfla00230]
D SPHFLASMR4Y_01356 act; methanol dehydrogenase activator K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D SPHFLASMR4Y_02409 prs; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SPHFLASMR4Y_01229 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SPHFLASMR4Y_03363 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D SPHFLASMR4Y_01331 purU; formyltetrahydrofolate deformylase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D SPHFLASMR4Y_00074 purT; phosphoribosylglycinamide formyltransferase 2 K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21]
D SPHFLASMR4Y_01898 purL; phosphoribosylformylglycinamidine synthase subunit PurL K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D SPHFLASMR4Y_02832 purS; phosphoribosylformylglycinamidine synthase subunit PurS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D SPHFLASMR4Y_02831 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SPHFLASMR4Y_01330 purM; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D SPHFLASMR4Y_01533 purT; phosphoribosylglycinamide formyltransferase 2 K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D SPHFLASMR4Y_01532 purE; N5-carboxyaminoimidazole ribonucleotide mutase K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D SPHFLASMR4Y_02835 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D SPHFLASMR4Y_01200 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D SPHFLASMR4Y_01541 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D SPHFLASMR4Y_02004 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D SPHFLASMR4Y_03019 surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D SPHFLASMR4Y_01600 yfiH; laccase domain protein YfiH K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D SPHFLASMR4Y_01245 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D SPHFLASMR4Y_01337 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D SPHFLASMR4Y_00155 non-canonical purine NTP pyrophosphatase K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D SPHFLASMR4Y_00555 xdhA; xanthine dehydrogenase molybdenum-binding subunit K11177 yagR; xanthine dehydrogenase YagR molybdenum-binding subunit [EC:1.17.1.4]
D SPHFLASMR4Y_00556 hcrB; 4-hydroxybenzoyl-CoA reductase subunit beta K11178 yagS; xanthine dehydrogenase YagS FAD-binding subunit [EC:1.17.1.4]
D SPHFLASMR4Y_00557 yagT; putative xanthine dehydrogenase YagT iron-sulfur-binding subunit K13483 yagT; xanthine dehydrogenase YagT iron-sulfur-binding subunit
D SPHFLASMR4Y_01918 guaA; GMP synthetase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SPHFLASMR4Y_03080 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D SPHFLASMR4Y_03398 nrdZ; vitamin B12-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPHFLASMR4Y_03400 nrdB; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SPHFLASMR4Y_00098 dgt; deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 dgt; dGTPase [EC:3.1.5.1]
D SPHFLASMR4Y_01970 rsh; GTP pyrophosphokinase rsh K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D SPHFLASMR4Y_01326 gppA; guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D SPHFLASMR4Y_00537 ppx; exopolyphosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D SPHFLASMR4Y_00018 cyaA; adenylate cyclase 1 K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
D SPHFLASMR4Y_00119 cya; adenylate cyclase K01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]
D SPHFLASMR4Y_02065 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D SPHFLASMR4Y_01818 amn; AMP nucleosidase K01241 amn; AMP nucleosidase [EC:3.2.2.4]
D SPHFLASMR4Y_01415 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D SPHFLASMR4Y_00774 mazG; nucleoside triphosphate hydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D SPHFLASMR4Y_01811 cpdA; 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA K03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]
D SPHFLASMR4Y_00221 tuf; elongation factor Tu K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D SPHFLASMR4Y_00220 cysD; sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D SPHFLASMR4Y_02573 Asp/Glu/Hydantoin racemase K16841 hpxA; allantoin racemase [EC:5.1.99.3]
D SPHFLASMR4Y_02576 allA; ureidoglycolate lyase K01483 allA; ureidoglycolate lyase [EC:4.3.2.3]
C 00240 Pyrimidine metabolism [PATH:sfla00240]
D SPHFLASMR4Y_01033 purT; phosphoribosylglycinamide formyltransferase 2 K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SPHFLASMR4Y_01035 guaA; GMP synthetase K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SPHFLASMR4Y_00903 pyrB; aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D SPHFLASMR4Y_00904 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D SPHFLASMR4Y_02484 pyrC; dihydroorotase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D SPHFLASMR4Y_03217 pyrD; dihydroorotate dehydrogenase (quinone) K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D SPHFLASMR4Y_03043 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D SPHFLASMR4Y_01202 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D SPHFLASMR4Y_01297 pyrH; UMP kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D SPHFLASMR4Y_01337 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D SPHFLASMR4Y_00774 mazG; nucleoside triphosphate hydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D SPHFLASMR4Y_00043 yhdE; Maf-like protein YhdE K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D SPHFLASMR4Y_02295 yceF; Maf-like protein YceF K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D SPHFLASMR4Y_01077 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D SPHFLASMR4Y_03254 cmk; cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D SPHFLASMR4Y_02326 udk; uridine kinase K00876 udk; uridine kinase [EC:2.7.1.48]
D SPHFLASMR4Y_03019 surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D SPHFLASMR4Y_00655 dcd; deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D SPHFLASMR4Y_01442 dcd; deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D SPHFLASMR4Y_03398 nrdZ; vitamin B12-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPHFLASMR4Y_03400 nrdB; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SPHFLASMR4Y_00780 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D SPHFLASMR4Y_02749 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SPHFLASMR4Y_00590 tdk; thymidine kinase K00857 tdk; thymidine kinase [EC:2.7.1.21]
D SPHFLASMR4Y_01145 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D SPHFLASMR4Y_01888 rutA; pyrimidine monooxygenase RutA K09018 rutA; pyrimidine oxygenase [EC:1.14.99.46]
D SPHFLASMR4Y_00695 rutE; putative malonic semialdehyde reductase RutE K09019 rutE; 3-hydroxypropanoate dehydrogenase [EC:1.1.1.-]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:sfla00250]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_03375 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D SPHFLASMR4Y_02798 racX; putative amino-acid racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
D SPHFLASMR4Y_02634 ansB; putative L-asparaginase periplasmic K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D SPHFLASMR4Y_01656 asnO; asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D SPHFLASMR4Y_00979 asnB; asparagine synthetase [glutamine-hydrolyzing] 1 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D SPHFLASMR4Y_00311 asnO; asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D SPHFLASMR4Y_02227 ald; alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D SPHFLASMR4Y_00583 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D SPHFLASMR4Y_02762 fumC; class II fumarate hydratase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D SPHFLASMR4Y_02065 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D SPHFLASMR4Y_01200 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D SPHFLASMR4Y_00903 pyrB; aspartate carbamoyltransferase catalytic subunit K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D SPHFLASMR4Y_00950 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01378 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_03062 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01471 gltB; ferredoxin-dependent glutamate synthase 1 K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D SPHFLASMR4Y_02531 gltB; glutamate synthase [NADPH] large chain K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D SPHFLASMR4Y_01472 gltD; glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D SPHFLASMR4Y_02533 gltD; glutamate synthase K00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]
D SPHFLASMR4Y_02084 gdhB; NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D SPHFLASMR4Y_01413 gdhA; NAD(P)-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D SPHFLASMR4Y_01333 putA; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D SPHFLASMR4Y_01516 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SPHFLASMR4Y_01033 purT; phosphoribosylglycinamide formyltransferase 2 K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SPHFLASMR4Y_01035 guaA; GMP synthetase K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SPHFLASMR4Y_03059 glsA; thermolabile glutaminase K01425 glsA; glutaminase [EC:3.5.1.2]
D SPHFLASMR4Y_02831 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SPHFLASMR4Y_00724 nodM; glutamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SPHFLASMR4Y_01229 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:sfla00260]
D SPHFLASMR4Y_02525 lysC; aspartate kinase Ask_LysC K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SPHFLASMR4Y_00858 asd2; aspartate-semialdehyde dehydrogenase 2 K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SPHFLASMR4Y_02886 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D SPHFLASMR4Y_00060 thrB; homoserine kinase K02204 thrB2; homoserine kinase type II [EC:2.7.1.39]
D SPHFLASMR4Y_03052 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D SPHFLASMR4Y_01605 ltaE; low specificity L-threonine aldolase K01620 ltaE; threonine aldolase [EC:4.1.2.48]
D SPHFLASMR4Y_01264 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SPHFLASMR4Y_01594 ttuD; putative hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SPHFLASMR4Y_01530 gpmA; phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SPHFLASMR4Y_02063 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D SPHFLASMR4Y_02062 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D SPHFLASMR4Y_00909 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
D SPHFLASMR4Y_00830 hemA; 5-aminolevulinate synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D SPHFLASMR4Y_02624 puo; putrescine oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D SPHFLASMR4Y_00103 gcvPA; putative glycine dehydrogenase (decarboxylating) subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D SPHFLASMR4Y_00104 gcvPB; putative glycine dehydrogenase (decarboxylating) subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D SPHFLASMR4Y_00101 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00102 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D SPHFLASMR4Y_01303 CDP-alcohol phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D SPHFLASMR4Y_02174 sdaB; L-serine dehydratase 2 K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D SPHFLASMR4Y_00831 tdcB; L-threonine dehydratase catabolic TdcB K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D SPHFLASMR4Y_00644 tdcB; L-threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D SPHFLASMR4Y_01205 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D SPHFLASMR4Y_01204 trpB; tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:sfla00270]
D SPHFLASMR4Y_00708 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
D SPHFLASMR4Y_00077 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D SPHFLASMR4Y_01221 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D SPHFLASMR4Y_02686 cysK; cysteine synthase K01738 cysK; cysteine synthase [EC:2.5.1.47]
D SPHFLASMR4Y_01840 metC; cystathionine beta-lyase MetC K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D SPHFLASMR4Y_03316 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D SPHFLASMR4Y_03317 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D SPHFLASMR4Y_02046 metK; S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D SPHFLASMR4Y_01600 yfiH; laccase domain protein YfiH K05810 LACC1; purine-nucleoside/S-methyl-5'-thioadenosine phosphorylase / adenosine deaminase [EC:2.4.2.1 2.4.2.28 3.5.4.4]
D SPHFLASMR4Y_01598 mgl; L-methionine gamma-lyase K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11]
D SPHFLASMR4Y_00650 msrC; free methionine-R-sulfoxide reductase K08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]
D SPHFLASMR4Y_01499 hpaIIM; modification methylase HpaII K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SPHFLASMR4Y_00847 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D SPHFLASMR4Y_02525 lysC; aspartate kinase Ask_LysC K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SPHFLASMR4Y_00858 asd2; aspartate-semialdehyde dehydrogenase 2 K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SPHFLASMR4Y_02886 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D SPHFLASMR4Y_02398 metX; homoserine O-acetyltransferase K00641 metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]
D SPHFLASMR4Y_03188 mgl; L-methionine gamma-lyase K01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]
D SPHFLASMR4Y_01179 metZ; O-succinylhomoserine sulfhydrylase K10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]
D SPHFLASMR4Y_02897 ilvE; branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SPHFLASMR4Y_02806 egtA; glutamate--cysteine ligase EgtA K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D SPHFLASMR4Y_00148 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_01839 sseA; 3-mercaptopyruvate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SPHFLASMR4Y_02193 mdh; malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SPHFLASMR4Y_02174 sdaB; L-serine dehydratase 2 K01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]
D SPHFLASMR4Y_02063 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D SPHFLASMR4Y_02062 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
C 00280 Valine, leucine and isoleucine degradation [PATH:sfla00280]
D SPHFLASMR4Y_02897 ilvE; branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SPHFLASMR4Y_01279 ldh; leucine dehydrogenase K00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]
D SPHFLASMR4Y_01144 bkdA1; 2-oxoisovalerate dehydrogenase subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D SPHFLASMR4Y_01143 bkdA2; 2-oxoisovalerate dehydrogenase subunit beta K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D SPHFLASMR4Y_01142 bkdB; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02664 carC; caffeyl-CoA reductase-Etf complex subunit CarC K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01522 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_00326 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01935 carC; caffeyl-CoA reductase-Etf complex subunit CarC K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_00923 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01387 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01396 carC; caffeyl-CoA reductase-Etf complex subunit CarC K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_01399 fadE; acyl-CoA dehydrogenase K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SPHFLASMR4Y_03218 fadE; acyl-CoA dehydrogenase K00253 IVD; isovaleryl-CoA dehydrogenase [EC:1.3.8.4]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00814 accA1; acetyl-/propionyl-coenzyme A carboxylase alpha chain K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D SPHFLASMR4Y_00820 pccB; propionyl-CoA carboxylase beta chain K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
D SPHFLASMR4Y_00818 cetB; 2-epi-5-epi-valiolone epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SPHFLASMR4Y_00816 scpA; methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D SPHFLASMR4Y_00127 mmsB; 3-hydroxyisobutyrate dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D SPHFLASMR4Y_00645 garR; 2-hydroxy-3-oxopropionate reductase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D SPHFLASMR4Y_00122 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_02105 yngG; hydroxymethylglutaryl-CoA lyase YngG K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D SPHFLASMR4Y_02345 ccl; (R)-citramalyl-CoA lyase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D SPHFLASMR4Y_01961 scoA; putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit A K01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]
D SPHFLASMR4Y_01959 scoB; putative succinyl-CoA:3-ketoacid coenzyme A transferase subunit B K01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:sfla00290]
D SPHFLASMR4Y_00831 tdcB; L-threonine dehydratase catabolic TdcB K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D SPHFLASMR4Y_00644 tdcB; L-threonine ammonia-lyase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D SPHFLASMR4Y_02107 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_02610 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_03227 leuC; 3-isopropylmalate dehydratase large subunit K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_02106 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_02609 leuD1; 3-isopropylmalate dehydratase small subunit 1 K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_03229 leuD; 3-isopropylmalate dehydratase small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SPHFLASMR4Y_01180 leuB; 3-isopropylmalate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D SPHFLASMR4Y_00911 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00011 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_03061 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_02970 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00912 ilvH; acetolactate synthase isozyme 3 small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00913 ilvC; ketol-acid reductoisomerase (NADP(+)) K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D SPHFLASMR4Y_00840 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D SPHFLASMR4Y_02897 ilvE; branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SPHFLASMR4Y_01279 ldh; leucine dehydrogenase K00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]
D SPHFLASMR4Y_00914 leuA; 2-isopropylmalate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:sfla00300]
D SPHFLASMR4Y_02886 hom; homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D SPHFLASMR4Y_02525 lysC; aspartate kinase Ask_LysC K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SPHFLASMR4Y_00858 asd2; aspartate-semialdehyde dehydrogenase 2 K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SPHFLASMR4Y_01314 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D SPHFLASMR4Y_02733 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
D SPHFLASMR4Y_02208 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase K00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]
D SPHFLASMR4Y_00730 astC; succinylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D SPHFLASMR4Y_02501 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D SPHFLASMR4Y_00866 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D SPHFLASMR4Y_00988 btrK; L-glutamyl-[BtrI acyl-carrier protein] decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D SPHFLASMR4Y_02764 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D SPHFLASMR4Y_00084 murC; UDP-N-acetylmuramate--L-alanine ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D SPHFLASMR4Y_00085 murC; UDP-N-acetylmuramate--L-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
C 00310 Lysine degradation [PATH:sfla00310]
D SPHFLASMR4Y_02190 sucB; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00950 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01378 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_03062 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01364 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00220 Arginine biosynthesis [PATH:sfla00220]
D SPHFLASMR4Y_00731 pyrB; aspartate carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D SPHFLASMR4Y_00583 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D SPHFLASMR4Y_02762 fumC; class II fumarate hydratase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D SPHFLASMR4Y_03059 glsA; thermolabile glutaminase K01425 glsA; glutaminase [EC:3.5.1.2]
D SPHFLASMR4Y_02831 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SPHFLASMR4Y_01516 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SPHFLASMR4Y_01033 purT; phosphoribosylglycinamide formyltransferase 2 K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SPHFLASMR4Y_01035 guaA; GMP synthetase K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SPHFLASMR4Y_02084 gdhB; NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D SPHFLASMR4Y_01413 gdhA; NAD(P)-specific glutamate dehydrogenase K00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_01059 oat2; glutamate N-acetyltransferase 2 K00620 argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]
D SPHFLASMR4Y_01574 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D SPHFLASMR4Y_03039 argC; N-acetyl-gamma-glutamyl-phosphate reductase K00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]
D SPHFLASMR4Y_00730 astC; succinylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D SPHFLASMR4Y_02636 argE; acetylornithine deacetylase K01438 argE; acetylornithine deacetylase [EC:3.5.1.16]
C 00330 Arginine and proline metabolism [PATH:sfla00330]
D SPHFLASMR4Y_02344 apc3; acetophenone carboxylase gamma subunit K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D SPHFLASMR4Y_02618 apc3; acetophenone carboxylase gamma subunit K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D SPHFLASMR4Y_02343 apc4; acetophenone carboxylase delta subunit K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D SPHFLASMR4Y_02617 apc4; acetophenone carboxylase delta subunit K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D SPHFLASMR4Y_01257 aguA; putative agmatine deiminase K10536 aguA; agmatine deiminase [EC:3.5.3.12]
D SPHFLASMR4Y_01254 nadE; NAD(+) synthase K12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]
D SPHFLASMR4Y_00834 ldc; lysine/ornithine decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
D SPHFLASMR4Y_00833 nspC; carboxynorspermidine/carboxyspermidine decarboxylase K13747 nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_02624 puo; putrescine oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D SPHFLASMR4Y_02188 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SPHFLASMR4Y_01346 aruG; arginine N-succinyltransferase subunit beta K00673 astA; arginine N-succinyltransferase [EC:2.3.1.109]
D SPHFLASMR4Y_01347 astB; N-succinylarginine dihydrolase K01484 astB; succinylarginine dihydrolase [EC:3.5.3.23]
D SPHFLASMR4Y_00664 astD; N-succinylglutamate 5-semialdehyde dehydrogenase K06447 astD; succinylglutamic semialdehyde dehydrogenase [EC:1.2.1.71]
D SPHFLASMR4Y_01645 proC; pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D SPHFLASMR4Y_01333 putA; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D SPHFLASMR4Y_01644 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D SPHFLASMR4Y_01862 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D SPHFLASMR4Y_02511 proA; gamma-glutamyl-phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
D SPHFLASMR4Y_01283 2OG-Fe(II) oxygenase superfamily protein K00472 P4HA; prolyl 4-hydroxylase [EC:1.14.11.2]
D SPHFLASMR4Y_02639 2OG-Fe(II) oxygenase superfamily protein K00472 P4HA; prolyl 4-hydroxylase [EC:1.14.11.2]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_01364 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
C 00340 Histidine metabolism [PATH:sfla00340]
D SPHFLASMR4Y_00030 hisG; ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D SPHFLASMR4Y_02064 hisZ; ATP phosphoribosyltransferase regulatory subunit K02502 hisZ; ATP phosphoribosyltransferase regulatory subunit
D SPHFLASMR4Y_03091 hisE; phosphoribosyl-ATP pyrophosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D SPHFLASMR4Y_01228 hisI; phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D SPHFLASMR4Y_03088 hisA; 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D SPHFLASMR4Y_03087 hisH; imidazole glycerol phosphate synthase subunit HisH K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D SPHFLASMR4Y_03089 hisF; imidazole glycerol phosphate synthase subunit HisF K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D SPHFLASMR4Y_03086 hisB; histidine biosynthesis bifunctional protein HisB K01693 hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]
D SPHFLASMR4Y_02397 pat; putative phenylalanine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SPHFLASMR4Y_02407 hisN; histidinol-phosphatase K05602 hisN; histidinol-phosphatase [EC:3.1.3.15]
D SPHFLASMR4Y_00031 hisD; histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_02624 puo; putrescine oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D SPHFLASMR4Y_01850 egtD; histidine N-alpha-methyltransferase K18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44]
C 00350 Tyrosine metabolism [PATH:sfla00350]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_02397 pat; putative phenylalanine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SPHFLASMR4Y_02690 hpd; 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
D SPHFLASMR4Y_02688 fumarylacetoacetate (FAA) hydrolase family protein K16171 faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]
D SPHFLASMR4Y_02991 ureidoglycolate lyase K16171 faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]
D SPHFLASMR4Y_02624 puo; putrescine oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D SPHFLASMR4Y_02614 gabD; succinate-semialdehyde dehydrogenase (NADP(+)) K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D SPHFLASMR4Y_02619 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D SPHFLASMR4Y_01385 flhA; S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01400 adhD; putative alcohol dehydrogenase D K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_02989 ligC; 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase K10219 ligC; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312]
D SPHFLASMR4Y_00950 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01378 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_03062 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00360 Phenylalanine metabolism [PATH:sfla00360]
D SPHFLASMR4Y_00604 phhA; phenylalanine-4-hydroxylase K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]
D SPHFLASMR4Y_02624 puo; putrescine oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D SPHFLASMR4Y_02614 gabD; succinate-semialdehyde dehydrogenase (NADP(+)) K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D SPHFLASMR4Y_02619 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D SPHFLASMR4Y_02137 paaK; phenylacetate-coenzyme A ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D SPHFLASMR4Y_02979 paaI; acyl-coenzyme A thioesterase PaaI K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-]
D SPHFLASMR4Y_00817 paaG; 1,2-epoxyphenylacetyl-CoA isomerase K15866 paaG; 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase [EC:5.3.3.18]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_01848 hbd; 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_02397 pat; putative phenylalanine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SPHFLASMR4Y_02690 hpd; 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
D SPHFLASMR4Y_01364 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D SPHFLASMR4Y_00729 katG; catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21]
D SPHFLASMR4Y_01389 katG; catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21]
D SPHFLASMR4Y_02188 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SPHFLASMR4Y_00997 fdr; ferredoxin--NAD(P)(+) reductase fdr K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D SPHFLASMR4Y_02977 mhpA; 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase K05712 mhpA; 3-(3-hydroxy-phenyl)propionate hydroxylase [EC:1.14.13.127]
C 00380 Tryptophan metabolism [PATH:sfla00380]
D SPHFLASMR4Y_03167 kynA; tryptophan 2,3-dioxygenase K00453 TDO2; tryptophan 2,3-dioxygenase [EC:1.13.11.11]
D SPHFLASMR4Y_00166 indoleamine 2,3-dioxygenase K00463 IDO; indoleamine 2,3-dioxygenase [EC:1.13.11.52]
D SPHFLASMR4Y_02190 sucB; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02624 puo; putrescine oxidase K00274 MAO; monoamine oxidase [EC:1.4.3.4]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_02188 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SPHFLASMR4Y_00534 katE; catalase C K03781 katE; catalase [EC:1.11.1.6]
D SPHFLASMR4Y_00729 katG; catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21]
D SPHFLASMR4Y_01389 katG; catalase-peroxidase K03782 katG; catalase-peroxidase [EC:1.11.1.21]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:sfla00400]
D SPHFLASMR4Y_03007 aroH; phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D SPHFLASMR4Y_00191 aroB; 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D SPHFLASMR4Y_02643 aroQ; 3-dehydroquinate dehydratase K03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]
D SPHFLASMR4Y_02294 aroE; shikimate dehydrogenase (NADP(+)) K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
D SPHFLASMR4Y_00192 aroK; shikimate kinase 1 K00891 aroK; shikimate kinase [EC:2.7.1.71]
D SPHFLASMR4Y_03256 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D SPHFLASMR4Y_02069 aroC; chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D SPHFLASMR4Y_01081 trpE; anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D SPHFLASMR4Y_01086 guaA; GMP synthetase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D SPHFLASMR4Y_01087 trpD; anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D SPHFLASMR4Y_01203 trpF; N-(5'-phosphoribosyl)anthranilate isomerase K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D SPHFLASMR4Y_01088 trpC; indole-3-glycerol phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D SPHFLASMR4Y_01205 trpA; tryptophan synthase subunit alpha K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D SPHFLASMR4Y_01204 trpB; tryptophan synthase beta chain K01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D SPHFLASMR4Y_01359 chorismate mutase K04092 tyrA1; chorismate mutase [EC:5.4.99.5]
D SPHFLASMR4Y_02396 tyrA; prephenate dehydrogenase K00220 tyrC; cyclohexadieny/prephenate dehydrogenase [EC:1.3.1.43 1.3.1.12]
D SPHFLASMR4Y_02056 pheA; P-protein K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_02397 pat; putative phenylalanine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SPHFLASMR4Y_00604 phhA; phenylalanine-4-hydroxylase K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:sfla00410]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_02250 panC; pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00122 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00140 mmsA; malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
C 00430 Taurine and hypotaurine metabolism [PATH:sfla00430]
D SPHFLASMR4Y_00258 ywrD; putative gamma-glutamyltransferase YwrD K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_03216 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_02227 ald; alanine dehydrogenase K00259 ald; alanine dehydrogenase [EC:1.4.1.1]
D SPHFLASMR4Y_02084 gdhB; NAD-specific glutamate dehydrogenase K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
C 00440 Phosphonate and phosphinate metabolism
D SPHFLASMR4Y_00776 putative hydrolase K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:sfla00450]
D SPHFLASMR4Y_01840 metC; cystathionine beta-lyase MetC K01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]
D SPHFLASMR4Y_03316 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D SPHFLASMR4Y_03317 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D SPHFLASMR4Y_01598 mgl; L-methionine gamma-lyase K01761 E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11]
D SPHFLASMR4Y_02465 sufS; cysteine desulfurase K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D SPHFLASMR4Y_00994 trxB; thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D SPHFLASMR4Y_00221 tuf; elongation factor Tu K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D SPHFLASMR4Y_00220 cysD; sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D SPHFLASMR4Y_00778 ileS; isoleucine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:sfla00460]
D SPHFLASMR4Y_00258 ywrD; putative gamma-glutamyltransferase YwrD K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_03216 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_02634 ansB; putative L-asparaginase periplasmic K01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]
D SPHFLASMR4Y_01264 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism [PATH:sfla00470]
D SPHFLASMR4Y_00812 alr1; alanine racemase 1 K01775 alr; alanine racemase [EC:5.1.1.1]
D SPHFLASMR4Y_01364 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D SPHFLASMR4Y_00093 ddlB; D-alanine--D-alanine ligase B K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SPHFLASMR4Y_03059 glsA; thermolabile glutaminase K01425 glsA; glutaminase [EC:3.5.1.2]
D SPHFLASMR4Y_02831 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SPHFLASMR4Y_00829 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D SPHFLASMR4Y_00087 murC; UDP-N-acetylmuramate--L-alanine ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D SPHFLASMR4Y_02772 ycjG; L-Ala-D/L-Glu epimerase K19802 ycjG; L-Ala-D/L-Glu epimerase / N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]
D SPHFLASMR4Y_02798 racX; putative amino-acid racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
D SPHFLASMR4Y_00866 dapF; diaminopimelate epimerase K01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]
D SPHFLASMR4Y_00988 btrK; L-glutamyl-[BtrI acyl-carrier protein] decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D SPHFLASMR4Y_02764 lysA; diaminopimelate decarboxylase K01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]
D SPHFLASMR4Y_00057 dauA; FAD-dependent catabolic D-arginine dehydrogenase DauA K19746 dauA; D-arginine dehydrogenase [EC:1.4.99.6]
C 00480 Glutathione metabolism [PATH:sfla00480]
D SPHFLASMR4Y_00258 ywrD; putative gamma-glutamyltransferase YwrD K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_03216 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_01285 LamB/YcsF family protein K07160 pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9]
D SPHFLASMR4Y_01286 kipI; kinase A inhibitor K23123 pxpB; 5-oxoprolinase (ATP-hydrolysing) subunit B [EC:3.5.2.9]
D SPHFLASMR4Y_01287 kipA; KipI antagonist K23124 pxpC; 5-oxoprolinase (ATP-hydrolysing) subunit C [EC:3.5.2.9]
D SPHFLASMR4Y_02806 egtA; glutamate--cysteine ligase EgtA K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D SPHFLASMR4Y_00148 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D SPHFLASMR4Y_01339 pepA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D SPHFLASMR4Y_03035 pepB; peptidase B K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D SPHFLASMR4Y_01601 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D SPHFLASMR4Y_00075 yibF; putative GST-like protein YibF K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_01309 gstB; glutathione S-transferase GST-6.0 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02092 yfcG; disulfide-bond oxidoreductase YfcG K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_00440 gstB; glutathione S-transferase GST-6.0 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02502 yfcF; glutathione S-transferase YfcF K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02528 gstB; glutathione S-transferase GstB K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_03221 sspA; stringent starvation protein A K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_03223 glutathionine S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02993 gst; glutathione S-transferase GST-4.5 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02256 MAPEG family protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02265 glutaredoxin 2 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_00821 garB; glutathione amide reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
D SPHFLASMR4Y_02918 garB; glutathione amide reductase K00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]
D SPHFLASMR4Y_01305 icd; isocitrate dehydrogenase [NADP] K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D SPHFLASMR4Y_01072 glutathione peroxidase K00432 gpx; glutathione peroxidase [EC:1.11.1.9]
D SPHFLASMR4Y_00849 hybrid peroxiredoxin hyPrx5 K24138 prx3; glutaredoxin/glutathione-dependent peroxiredoxin [EC:1.11.1.25 1.11.1.27]
D SPHFLASMR4Y_00834 ldc; lysine/ornithine decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis [PATH:sfla00541]
D SPHFLASMR4Y_02018 gtaB; UTP--glucose-1-phosphate uridylyltransferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SPHFLASMR4Y_02221 galE; UDP-glucose 4-epimerase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D SPHFLASMR4Y_02444 rkpK; UDP-glucose 6-dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SPHFLASMR4Y_02443 wbgU; UDP-N-acetylglucosamine 4-epimerase K08679 GAE; UDP-glucuronate 4-epimerase [EC:5.1.3.6]
D SPHFLASMR4Y_00283 manA; mannose-6-phosphate isomerase ManA K01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]
D SPHFLASMR4Y_02253 algC; phosphomannomutase/phosphoglucomutase K01840 manB; phosphomannomutase [EC:5.4.2.8]
D SPHFLASMR4Y_00282 cpsB; mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase K00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D SPHFLASMR4Y_00721 glmU; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase K04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]
D SPHFLASMR4Y_00280 wecB; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D SPHFLASMR4Y_02426 wbpI; UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D SPHFLASMR4Y_00279 wecC; UDP-N-acetyl-D-mannosamine dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D SPHFLASMR4Y_02429 capD; UDP-glucose 4-epimerase K15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase [EC:4.2.1.115 5.1.3.-]
D SPHFLASMR4Y_02428 wbjC; UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase K19068 wbjC; UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase [EC:1.1.1.367]
D SPHFLASMR4Y_00284 pglF; UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135]
C 00550 Peptidoglycan biosynthesis [PATH:sfla00550]
D SPHFLASMR4Y_02494 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SPHFLASMR4Y_00092 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D SPHFLASMR4Y_00090 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D SPHFLASMR4Y_00286 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D SPHFLASMR4Y_00087 murC; UDP-N-acetylmuramate--L-alanine ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D SPHFLASMR4Y_00084 murC; UDP-N-acetylmuramate--L-alanine ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D SPHFLASMR4Y_00093 ddlB; D-alanine--D-alanine ligase B K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SPHFLASMR4Y_00085 murC; UDP-N-acetylmuramate--L-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D SPHFLASMR4Y_01295 ispU; ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D SPHFLASMR4Y_02534 uppP; undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SPHFLASMR4Y_00086 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D SPHFLASMR4Y_00089 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D SPHFLASMR4Y_00892 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28]
D SPHFLASMR4Y_02281 pbpG; penicillin-binding protein 2D K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00022 pbpF; penicillin-binding protein 1F K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00543 mrcA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00946 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D SPHFLASMR4Y_00083 ftsI; peptidoglycan synthase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D SPHFLASMR4Y_00781 dacC; D-alanyl-D-alanine carboxypeptidase DacC K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis [PATH:sfla00552]
D SPHFLASMR4Y_02534 uppP; undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SPHFLASMR4Y_00284 pglF; UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase K24300 wbpM; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.135]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis [PATH:sfla00543]
D SPHFLASMR4Y_00708 cysE; serine acetyltransferase K00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:sfla00730]
D SPHFLASMR4Y_00474 thiC; phosphomethylpyrimidine synthase K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D SPHFLASMR4Y_00637 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D SPHFLASMR4Y_00959 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_00960 iscS; IscS-like cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_02206 dxs; 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D SPHFLASMR4Y_02644 thiG; thiazole synthase K03149 thiG; thiazole synthase [EC:2.8.1.10]
D SPHFLASMR4Y_01129 thiE; thiamine-phosphate synthase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D SPHFLASMR4Y_00035 thiL; thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D SPHFLASMR4Y_01415 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:sfla00740]
D SPHFLASMR4Y_03341 ribA; GTP cyclohydrolase-2 K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D SPHFLASMR4Y_02699 ribBA; riboflavin biosynthesis protein RibBA K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D SPHFLASMR4Y_02414 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D SPHFLASMR4Y_02698 ribH1; 6,7-dimethyl-8-ribityllumazine synthase 1 K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D SPHFLASMR4Y_02415 ribE; riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D SPHFLASMR4Y_01536 ribF; riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D SPHFLASMR4Y_02324 azo1; FMN-dependent NADPH-azoreductase K00299 ssuE; FMN reductase [EC:1.5.1.38]
D SPHFLASMR4Y_01356 act; methanol dehydrogenase activator K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
C 00750 Vitamin B6 metabolism [PATH:sfla00750]
D SPHFLASMR4Y_02074 pdxH; pyridoxine/pyridoxamine 5'-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]
D SPHFLASMR4Y_02062 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
D SPHFLASMR4Y_01342 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase K00097 pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262]
D SPHFLASMR4Y_03042 pdxJ; pyridoxine 5'-phosphate synthase K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]
D SPHFLASMR4Y_03052 thrC; threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
C 00760 Nicotinate and nicotinamide metabolism [PATH:sfla00760]
D SPHFLASMR4Y_03375 nadB; L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D SPHFLASMR4Y_03240 nadA; quinolinate synthase A K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D SPHFLASMR4Y_03243 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D SPHFLASMR4Y_03019 surE; 5'-nucleotidase SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D SPHFLASMR4Y_02512 nadD; putative nicotinate-nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D SPHFLASMR4Y_00774 mazG; nucleoside triphosphate hydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D SPHFLASMR4Y_03286 nudC; NADH pyrophosphatase K03426 NUDT12_13; NAD+ diphosphatase [EC:3.6.1.22]
D SPHFLASMR4Y_02410 nadE; NAD(+) synthase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D SPHFLASMR4Y_00764 pncC; nicotinamide-nucleotide amidohydrolase PncC K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D SPHFLASMR4Y_02734 cobB; NAD-dependent protein deacylase K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D SPHFLASMR4Y_01053 ppnK; NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
D SPHFLASMR4Y_02795 pntAA; NAD(P) transhydrogenase subunit alpha part 1 K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]
D SPHFLASMR4Y_02796 pntA; NAD(P) transhydrogenase subunit alpha K00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]
D SPHFLASMR4Y_02797 pntB; NAD(P) transhydrogenase subunit beta K00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1]
D SPHFLASMR4Y_02608 nicF; maleamate amidohydrolase K13995 nicF; maleamate amidohydrolase [EC:3.5.1.107]
D SPHFLASMR4Y_02110 nicF; maleamate amidohydrolase K13995 nicF; maleamate amidohydrolase [EC:3.5.1.107]
D SPHFLASMR4Y_02621 maiA; maleate isomerase K01799 nicE; maleate isomerase [EC:5.2.1.1]
D SPHFLASMR4Y_00950 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_01378 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
D SPHFLASMR4Y_03062 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00135 gabD; succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
C 00770 Pantothenate and CoA biosynthesis [PATH:sfla00770]
D SPHFLASMR4Y_00911 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00011 alsS; acetolactate synthase K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_03061 ilvI; acetolactate synthase isozyme 3 large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_02970 ilvB; acetolactate synthase large subunit K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00912 ilvH; acetolactate synthase isozyme 3 small subunit K01653 E2.2.1.6S; acetolactate synthase I/III small subunit [EC:2.2.1.6]
D SPHFLASMR4Y_00913 ilvC; ketol-acid reductoisomerase (NADP(+)) K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D SPHFLASMR4Y_00840 ilvD; dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D SPHFLASMR4Y_01911 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D SPHFLASMR4Y_02250 panC; pantothenate synthetase K01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]
D SPHFLASMR4Y_01105 coaX; type III pantothenate kinase K03525 coaX; type III pantothenate kinase [EC:2.7.1.33]
D SPHFLASMR4Y_02750 coaBC; coenzyme A biosynthesis bifunctional protein CoaBC K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D SPHFLASMR4Y_00774 mazG; nucleoside triphosphate hydrolase K04765 mazG; nucleoside triphosphate diphosphatase [EC:3.6.1.9]
D SPHFLASMR4Y_01892 coaD; phosphopantetheine adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D SPHFLASMR4Y_02293 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D SPHFLASMR4Y_03041 acpS; holo-[acyl-carrier-protein] synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
D SPHFLASMR4Y_02897 ilvE; branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
C 00780 Biotin metabolism [PATH:sfla00780]
D SPHFLASMR4Y_00918 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D SPHFLASMR4Y_00162 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00920 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02590 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02338 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02352 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02353 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_03135 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02655 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02662 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00609 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_01289 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D SPHFLASMR4Y_02070 fabI; enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D SPHFLASMR4Y_01866 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D SPHFLASMR4Y_02268 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D SPHFLASMR4Y_02270 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D SPHFLASMR4Y_02269 bioD1; ATP-dependent dethiobiotin synthetase BioD 1 K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D SPHFLASMR4Y_00815 fbiC; 2-phospho-L-lactate guanylyltransferase K01012 bioB; biotin synthase [EC:2.8.1.6]
D SPHFLASMR4Y_01106 birA; bifunctional ligase/repressor BirA K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:sfla00785]
D SPHFLASMR4Y_00737 lipB; octanoyltransferase K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D SPHFLASMR4Y_00762 lipA; lipoyl synthase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D SPHFLASMR4Y_00259 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase K16869 lipL; octanoyl-[GcvH]:protein N-octanoyltransferase [EC:2.3.1.204]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_01023 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D SPHFLASMR4Y_01022 bfmBAB; 2-oxoisovalerate dehydrogenase subunit beta K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D SPHFLASMR4Y_00806 pdhC; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SPHFLASMR4Y_02191 sucA; 2-oxoglutarate dehydrogenase subunit E1 K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D SPHFLASMR4Y_02190 sucB; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D SPHFLASMR4Y_01144 bkdA1; 2-oxoisovalerate dehydrogenase subunit alpha K00166 BCKDHA; 2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
D SPHFLASMR4Y_01143 bkdA2; 2-oxoisovalerate dehydrogenase subunit beta K00167 BCKDHB; 2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:1.2.4.4]
D SPHFLASMR4Y_01142 bkdB; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex K09699 DBT; 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168]
D SPHFLASMR4Y_00103 gcvPA; putative glycine dehydrogenase (decarboxylating) subunit 1 K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D SPHFLASMR4Y_00104 gcvPB; putative glycine dehydrogenase (decarboxylating) subunit 2 K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D SPHFLASMR4Y_00101 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SPHFLASMR4Y_00102 gcvH; glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:sfla00790]
D SPHFLASMR4Y_00928 folE; GTP cyclohydrolase 1 K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D SPHFLASMR4Y_03139 pld; phospholipase D K01113 phoD; alkaline phosphatase D [EC:3.1.3.1]
D SPHFLASMR4Y_03054 dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D SPHFLASMR4Y_00435 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D SPHFLASMR4Y_00641 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D SPHFLASMR4Y_01534 dhfrIII; dihydrofolate reductase type 3 K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D SPHFLASMR4Y_01207 folC; bifunctional protein FolC K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D SPHFLASMR4Y_03341 ribA; GTP cyclohydrolase-2 K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D SPHFLASMR4Y_02699 ribBA; riboflavin biosynthesis protein RibBA K14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]
D SPHFLASMR4Y_03175 pabB; aminodeoxychorismate synthase component 1 K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
D SPHFLASMR4Y_01631 phhB; putative pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D SPHFLASMR4Y_00604 phhA; phenylalanine-4-hydroxylase K00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]
D SPHFLASMR4Y_00735 queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D SPHFLASMR4Y_00734 queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D SPHFLASMR4Y_01837 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D SPHFLASMR4Y_01052 moaA; cyclic pyranopterin phosphate synthase K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D SPHFLASMR4Y_01089 moaC; cyclic pyranopterin monophosphate synthase accessory protein K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D SPHFLASMR4Y_00706 moaE; molybdopterin synthase catalytic subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D SPHFLASMR4Y_01068 moaB; molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D SPHFLASMR4Y_01090 moeA; molybdopterin molybdenumtransferase K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D SPHFLASMR4Y_02331 pucB; purine catabolism protein PucB K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
D SPHFLASMR4Y_01463 mobA; molybdenum cofactor guanylyltransferase K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:sfla00670]
D SPHFLASMR4Y_01534 dhfrIII; dihydrofolate reductase type 3 K00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]
D SPHFLASMR4Y_01572 folD; bifunctional protein FolD protein K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D SPHFLASMR4Y_01264 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SPHFLASMR4Y_01331 purU; formyltetrahydrofolate deformylase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D SPHFLASMR4Y_01541 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D SPHFLASMR4Y_00977 purU; formyltetrahydrofolate deformylase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D SPHFLASMR4Y_00101 gcvT; aminomethyltransferase K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SPHFLASMR4Y_03316 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D SPHFLASMR4Y_03317 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D SPHFLASMR4Y_01145 thyA; thymidylate synthase K00560 thyA; thymidylate synthase [EC:2.1.1.45]
D SPHFLASMR4Y_01386 purU; formyltetrahydrofolate deformylase K01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]
D SPHFLASMR4Y_03318 metF; 5,10-methylenetetrahydrofolate reductase K00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]
D SPHFLASMR4Y_01136 ygfA; 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:sfla00860]
D SPHFLASMR4Y_00830 hemA; 5-aminolevulinate synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D SPHFLASMR4Y_01096 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_02411 gltX1; glutamate--tRNA ligase 1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_02036 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D SPHFLASMR4Y_01770 hemC; porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D SPHFLASMR4Y_01769 uroporphyrinogen-III synthase K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D SPHFLASMR4Y_02297 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D SPHFLASMR4Y_00740 hemF; oxygen-dependent coproporphyrinogen-III oxidase K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]
D SPHFLASMR4Y_02298 membrane protein K08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-]
D SPHFLASMR4Y_01826 hemH; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D SPHFLASMR4Y_02765 cysG; siroheme synthase K02302 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
D SPHFLASMR4Y_00663 cysG; siroheme synthase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D SPHFLASMR4Y_02547 cysG; siroheme synthase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D SPHFLASMR4Y_03046 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D SPHFLASMR4Y_02203 ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D SPHFLASMR4Y_00024 cobS; aerobic cobaltochelatase subunit CobS K09882 cobS; cobaltochelatase CobS [EC:6.6.1.2]
D SPHFLASMR4Y_00021 cobT; aerobic cobaltochelatase subunit CobT K09883 cobT; cobaltochelatase CobT [EC:6.6.1.2]
D SPHFLASMR4Y_01852 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D SPHFLASMR4Y_01906 bfr; bacterioferritin K03594 bfr; bacterioferritin [EC:1.16.3.1]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:sfla00130]
D SPHFLASMR4Y_03266 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D SPHFLASMR4Y_02526 ubiG; ubiquinone biosynthesis O-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64]
D SPHFLASMR4Y_03345 ubiF; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]
D SPHFLASMR4Y_02753 ubiE; bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D SPHFLASMR4Y_02518 coq7; 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase K06134 COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60]
D SPHFLASMR4Y_02690 hpd; 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:sfla00900]
D SPHFLASMR4Y_02206 dxs; 1-deoxy-D-xylulose-5-phosphate synthase K01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]
D SPHFLASMR4Y_01293 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D SPHFLASMR4Y_00766 ispDF; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K12506 ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12]
D SPHFLASMR4Y_00842 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D SPHFLASMR4Y_01794 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D SPHFLASMR4Y_00061 ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_01893 farnesyl diphosphate synthase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D SPHFLASMR4Y_01358 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D SPHFLASMR4Y_01295 ispU; ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis [PATH:sfla00906]
D SPHFLASMR4Y_00463 crtB; all-trans-phytoene synthase/15-cis-phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D SPHFLASMR4Y_01018 squalene/phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D SPHFLASMR4Y_00464 crtI; phytoene desaturase (lycopene-forming) K10027 crtI; phytoene desaturase [EC:1.3.99.26 1.3.99.28 1.3.99.29 1.3.99.31]
D SPHFLASMR4Y_00465 lycopene cyclase protein K06443 lcyB; lycopene beta-cyclase [EC:5.5.1.19]
D SPHFLASMR4Y_03225 fatty acid hydroxylase superfamily protein K15746 crtZ; beta-carotene 3-hydroxylase [EC:1.14.15.24]
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation [PATH:sfla00903]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_01933 limA; limonene-1,2-epoxide hydrolase K10533 E3.3.2.8; limonene-1,2-epoxide hydrolase [EC:3.3.2.8]
D SPHFLASMR4Y_03196 mlhB; monoterpene epsilon-lactone hydrolase K14731 mlhB; epsilon-lactone hydrolase [EC:3.1.1.83]
C 00907 Pinene, camphor and geraniol degradation [PATH:sfla00907]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_03374 ahr; aldehyde reductase Ahr K12957 ahr; alcohol/geraniol dehydrogenase (NADP+) [EC:1.1.1.2 1.1.1.183]
D SPHFLASMR4Y_02317 accA1; acetyl-/propionyl-coenzyme A carboxylase alpha chain K13777 atuF; geranyl-CoA carboxylase alpha subunit [EC:6.4.1.5]
D SPHFLASMR4Y_02319 methylmalonyl-CoA carboxyltransferase 12S subunit K13778 atuC; geranyl-CoA carboxylase beta subunit [EC:6.4.1.5]
D SPHFLASMR4Y_02318 caiD; carnitinyl-CoA dehydratase K13779 atuE; isohexenylglutaconyl-CoA hydratase [EC:4.2.1.57]
D SPHFLASMR4Y_02105 yngG; hydroxymethylglutaryl-CoA lyase YngG K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
D SPHFLASMR4Y_02345 ccl; (R)-citramalyl-CoA lyase K01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D SPHFLASMR4Y_01133 tktA; transketolase 1 K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
D SPHFLASMR4Y_00185 metallo-beta-lactamase superfamily protein K05555 actIV; cyclase [EC:4.-.-.-]
D SPHFLASMR4Y_02679 metallo-beta-lactamase superfamily protein K05555 actIV; cyclase [EC:4.-.-.-]
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures [PATH:sfla01054]
D SPHFLASMR4Y_02798 racX; putative amino-acid racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
C 01053 Biosynthesis of siderophore group nonribosomal peptides
D SPHFLASMR4Y_01261 isochorismate-pyruvate lyase K04782 pchB; isochorismate pyruvate lyase [EC:4.2.99.21]
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids [PATH:sfla00996]
D SPHFLASMR4Y_00329 hydroxycinnamoyl-CoA hydratase-lyase K18383 ferB; feruloyl-CoA hydratase/lyase [EC:4.1.2.61]
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
D SPHFLASMR4Y_03323 smeA; carbapenem-hydrolyzing beta-lactamase Sme-1 K17836 penP; beta-lactamase class A [EC:3.5.2.6]
C 00332 Carbapenem biosynthesis [PATH:sfla00332]
D SPHFLASMR4Y_01644 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D SPHFLASMR4Y_01862 proB; glutamate 5-kinase K00931 proB; glutamate 5-kinase [EC:2.7.2.11]
D SPHFLASMR4Y_02511 proA; gamma-glutamyl-phosphate reductase K00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]
C 00261 Monobactam biosynthesis [PATH:sfla00261]
D SPHFLASMR4Y_00221 tuf; elongation factor Tu K00955 cysNC; bifunctional enzyme CysN/CysC [EC:2.7.7.4 2.7.1.25]
D SPHFLASMR4Y_00220 cysD; sulfate adenylyltransferase subunit 2 K00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]
D SPHFLASMR4Y_02525 lysC; aspartate kinase Ask_LysC K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SPHFLASMR4Y_00858 asd2; aspartate-semialdehyde dehydrogenase 2 K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SPHFLASMR4Y_01314 dapA; 4-hydroxy-tetrahydrodipicolinate synthase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D SPHFLASMR4Y_02733 dapB; 4-hydroxy-tetrahydrodipicolinate reductase K00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis
D SPHFLASMR4Y_01126 suhB; inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D SPHFLASMR4Y_00462 suhB; fructose-1,6-bisphosphatase/inositol-1-monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis [PATH:sfla00401]
D SPHFLASMR4Y_02396 tyrA; prephenate dehydrogenase K00220 tyrC; cyclohexadieny/prephenate dehydrogenase [EC:1.3.1.43 1.3.1.12]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_02397 pat; putative phenylalanine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
D SPHFLASMR4Y_00642 rebH; flavin-dependent tryptophan halogenase RebH K14266 prnA; tryptophan 7-halogenase [EC:1.14.19.9]
D SPHFLASMR4Y_00643 rebH; flavin-dependent tryptophan halogenase RebH K14266 prnA; tryptophan 7-halogenase [EC:1.14.19.9]
C 00405 Phenazine biosynthesis
D SPHFLASMR4Y_01081 trpE; anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D SPHFLASMR4Y_01086 guaA; GMP synthetase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D SPHFLASMR4Y_00921 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D SPHFLASMR4Y_00162 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00920 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02590 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02338 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02352 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02353 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_03135 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02655 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02662 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00609 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02070 fabI; enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D SPHFLASMR4Y_00919 acpP; acyl carrier protein K02078 acpP; acyl carrier protein
D SPHFLASMR4Y_01865 acyl carrier protein K02078 acpP; acyl carrier protein
D SPHFLASMR4Y_00991 acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites [PATH:sfla00999]
D SPHFLASMR4Y_02046 metK; S-adenosylmethionine synthase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D SPHFLASMR4Y_02294 aroE; shikimate dehydrogenase (NADP(+)) K00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:sfla00362]
D SPHFLASMR4Y_02368 tesE; 2-hydroxyhexa-2,4-dienoate hydratase K18364 bphH; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
D SPHFLASMR4Y_02366 bphI; 4-hydroxy-2-oxovalerate aldolase 4 K18365 bphI; 4-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase [EC:4.1.3.39 4.1.3.43]
D SPHFLASMR4Y_02367 bphJ; acetaldehyde dehydrogenase 4 K18366 bphJ; acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]
D SPHFLASMR4Y_03291 carboxymuconolactone decarboxylase family protein K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D SPHFLASMR4Y_02987 ligA; protocatechuate 4,5-dioxygenase alpha chain K04100 ligA; protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8]
D SPHFLASMR4Y_02988 ligB; protocatechuate 4,5-dioxygenase beta chain K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
D SPHFLASMR4Y_02362 ligB; protocatechuate 4,5-dioxygenase beta chain K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
D SPHFLASMR4Y_02989 ligC; 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase K10219 ligC; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312]
D SPHFLASMR4Y_02981 ligI; 2-pyrone-4,6-dicarbaxylate hydrolase K10221 ligI; 2-pyrone-4,6-dicarboxylate lactonase [EC:3.1.1.57]
D SPHFLASMR4Y_02982 galD; 4-oxalomesaconate tautomerase K16514 galD; 4-oxalomesaconate tautomerase [EC:5.3.2.8]
D SPHFLASMR4Y_02986 amidohydrolase K10220 ligJ; 4-oxalmesaconate hydratase [EC:4.2.1.83]
D SPHFLASMR4Y_02983 proA; 4-hydroxy-4-methyl-2-oxoglutarate aldolase/4-carboxy-4-hydroxy-2-oxoadipate aldolase K10218 ligK; 4-hydroxy-4-methyl-2-oxoglutarate aldolase [EC:4.1.3.17]
D SPHFLASMR4Y_02994 cytochrome p450 CYP199A2 K22553 CYP199A2; 4-methoxybenzoate monooxygenase (O-demethylating) [EC:1.14.99.15]
D SPHFLASMR4Y_00997 fdr; ferredoxin--NAD(P)(+) reductase fdr K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D SPHFLASMR4Y_00410 fdxE; ferredoxin-6 K04755 fdx; ferredoxin, 2Fe-2S
D SPHFLASMR4Y_00432 fdxE; ferredoxin-6 K04755 fdx; ferredoxin, 2Fe-2S
D SPHFLASMR4Y_01624 thcC; rhodocoxin K04755 fdx; ferredoxin, 2Fe-2S
D SPHFLASMR4Y_00330 pobA; p-hydroxybenzoate hydroxylase K00481 pobA; p-hydroxybenzoate 3-monooxygenase [EC:1.14.13.2]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
D SPHFLASMR4Y_00794 fadB; fatty acid oxidation complex subunit alpha K07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_01848 hbd; 3-hydroxybutyryl-CoA dehydrogenase K00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:sfla00627]
D SPHFLASMR4Y_03032 ethA; FAD-containing monooxygenase EthA K10215 ethA; monooxygenase [EC:1.14.13.-]
D SPHFLASMR4Y_03034 ethA; FAD-containing monooxygenase EthA K10215 ethA; monooxygenase [EC:1.14.13.-]
D SPHFLASMR4Y_02188 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SPHFLASMR4Y_02557 andAb; anthranilate 1,2-dioxygenase ferredoxin subunit K18248 andAb; anthranilate 1,2-dioxygenase ferredoxin component
D SPHFLASMR4Y_02987 ligA; protocatechuate 4,5-dioxygenase alpha chain K04100 ligA; protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8]
D SPHFLASMR4Y_02988 ligB; protocatechuate 4,5-dioxygenase beta chain K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
D SPHFLASMR4Y_02362 ligB; protocatechuate 4,5-dioxygenase beta chain K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
D SPHFLASMR4Y_02989 ligC; 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase K10219 ligC; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase [EC:1.1.1.312]
D SPHFLASMR4Y_02981 ligI; 2-pyrone-4,6-dicarbaxylate hydrolase K10221 ligI; 2-pyrone-4,6-dicarboxylate lactonase [EC:3.1.1.57]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
C 00364 Fluorobenzoate degradation [PATH:sfla00364]
D SPHFLASMR4Y_02303 clcD; carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00625 Chloroalkane and chloroalkene degradation [PATH:sfla00625]
D SPHFLASMR4Y_01800 dhlA; haloalkane dehalogenase K01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]
D SPHFLASMR4Y_02611 dhmA2; haloalkane dehalogenase 2 K01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]
D SPHFLASMR4Y_01385 flhA; S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01400 adhD; putative alcohol dehydrogenase D K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01889 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]
D SPHFLASMR4Y_02220 D-glucose-1-phosphatase K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]
C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:sfla00361]
D SPHFLASMR4Y_01800 dhlA; haloalkane dehalogenase K01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]
D SPHFLASMR4Y_02611 dhmA2; haloalkane dehalogenase 2 K01563 dhaA; haloalkane dehalogenase [EC:3.8.1.5]
D SPHFLASMR4Y_02303 clcD; carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
D SPHFLASMR4Y_02220 D-glucose-1-phosphatase K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]
C 00623 Toluene degradation [PATH:sfla00623]
D SPHFLASMR4Y_02303 clcD; carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
C 00622 Xylene degradation [PATH:sfla00622]
D SPHFLASMR4Y_02368 tesE; 2-hydroxyhexa-2,4-dienoate hydratase K18364 bphH; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
D SPHFLASMR4Y_02366 bphI; 4-hydroxy-2-oxovalerate aldolase 4 K18365 bphI; 4-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase [EC:4.1.3.39 4.1.3.43]
D SPHFLASMR4Y_02367 bphJ; acetaldehyde dehydrogenase 4 K18366 bphJ; acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]
C 00633 Nitrotoluene degradation [PATH:sfla00633]
D SPHFLASMR4Y_01191 nfsB; oxygen-insensitive NAD(P)H nitroreductase K10679 nfnB; nitroreductase / dihydropteridine reductase [EC:1.-.-.- 1.5.1.34]
D SPHFLASMR4Y_03334 fadH; 2,4-dienoyl-CoA reductase K10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-]
C 00642 Ethylbenzene degradation
D SPHFLASMR4Y_02361 hcaE; 3-phenylpropionate/cinnamic acid dioxygenase subunit alpha K14748 etbAa; ethylbenzene dioxygenase subunit alpha [EC:1.14.12.-]
D SPHFLASMR4Y_02360 bphE; biphenyl dioxygenase subunit beta K14749 etbAb; ethylbenzene dioxygenase subunit beta [EC:1.14.12.-]
C 00643 Styrene degradation [PATH:sfla00643]
D SPHFLASMR4Y_02614 gabD; succinate-semialdehyde dehydrogenase (NADP(+)) K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D SPHFLASMR4Y_02619 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00146 feaB; phenylacetaldehyde dehydrogenase [EC:1.2.1.39]
D SPHFLASMR4Y_02688 fumarylacetoacetate (FAA) hydrolase family protein K16171 faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]
D SPHFLASMR4Y_02991 ureidoglycolate lyase K16171 faaH; fumarylacetoacetate (FAA) hydrolase [EC:3.7.1.2]
D SPHFLASMR4Y_02188 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00791 Atrazine degradation
C 00930 Caprolactam degradation [PATH:sfla00930]
D SPHFLASMR4Y_02170 inhA; isonitrile hydratase K18199 inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103]
D SPHFLASMR4Y_00404 alkB1; alkane 1-monooxygenase 1 K00496 alkB1_2; alkane 1-monooxygenase [EC:1.14.15.3]
D SPHFLASMR4Y_03063 gnl; gluconolactonase K01053 gnl; gluconolactonase [EC:3.1.1.17]
D SPHFLASMR4Y_03196 mlhB; monoterpene epsilon-lactone hydrolase K14731 mlhB; epsilon-lactone hydrolase [EC:3.1.1.83]
D SPHFLASMR4Y_00126 echA8; putative enoyl-CoA hydratase echA8 K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SPHFLASMR4Y_02321 fadJ; fatty acid oxidation complex subunit alpha K01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]
C 00363 Bisphenol degradation
C 00621 Dioxin degradation [PATH:sfla00621]
D SPHFLASMR4Y_02368 tesE; 2-hydroxyhexa-2,4-dienoate hydratase K18364 bphH; 2-oxopent-4-enoate/cis-2-oxohex-4-enoate hydratase [EC:4.2.1.80 4.2.1.132]
D SPHFLASMR4Y_02366 bphI; 4-hydroxy-2-oxovalerate aldolase 4 K18365 bphI; 4-hydroxy-2-oxovalerate/4-hydroxy-2-oxohexanoate aldolase [EC:4.1.3.39 4.1.3.43]
D SPHFLASMR4Y_02367 bphJ; acetaldehyde dehydrogenase 4 K18366 bphJ; acetaldehyde/propanal dehydrogenase [EC:1.2.1.10 1.2.1.87]
C 00626 Naphthalene degradation [PATH:sfla00626]
D SPHFLASMR4Y_01385 flhA; S-(hydroxymethyl)glutathione dehydrogenase K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
D SPHFLASMR4Y_01400 adhD; putative alcohol dehydrogenase D K00121 frmA; S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
D SPHFLASMR4Y_02987 ligA; protocatechuate 4,5-dioxygenase alpha chain K04100 ligA; protocatechuate 4,5-dioxygenase, alpha chain [EC:1.13.11.8]
D SPHFLASMR4Y_02988 ligB; protocatechuate 4,5-dioxygenase beta chain K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
D SPHFLASMR4Y_02362 ligB; protocatechuate 4,5-dioxygenase beta chain K04101 ligB; protocatechuate 4,5-dioxygenase, beta chain [EC:1.13.11.8]
C 00365 Furfural degradation
C 00984 Steroid degradation [PATH:sfla00984]
D SPHFLASMR4Y_02381 kstD; 3-oxosteroid 1-dehydrogenase K05898 kstD; 3-oxosteroid 1-dehydrogenase [EC:1.3.99.4]
D SPHFLASMR4Y_01334 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K05296 E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
D SPHFLASMR4Y_01377 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K05296 E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
D SPHFLASMR4Y_01932 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K05296 E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
D SPHFLASMR4Y_01860 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K05296 E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
D SPHFLASMR4Y_01233 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K05296 E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
D SPHFLASMR4Y_01938 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K05296 E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]
D SPHFLASMR4Y_01939 ksi; steroid Delta-isomerase K01822 E5.3.3.1; steroid Delta-isomerase [EC:5.3.3.1]
D SPHFLASMR4Y_02380 ifcA; fumarate reductase flavoprotein subunit K16051 tesI; 3-oxo-5alpha-steroid 4-dehydrogenase [EC:1.3.99.5]
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:sfla03020]
D SPHFLASMR4Y_02009 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D SPHFLASMR4Y_02010 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D SPHFLASMR4Y_01407 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D SPHFLASMR4Y_03325 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:sfla03010]
D SPHFLASMR4Y_03253 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D SPHFLASMR4Y_01299 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D SPHFLASMR4Y_01430 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D SPHFLASMR4Y_01259 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D SPHFLASMR4Y_01419 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D SPHFLASMR4Y_00925 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D SPHFLASMR4Y_01440 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D SPHFLASMR4Y_01422 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D SPHFLASMR4Y_02201 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D SPHFLASMR4Y_01437 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D SPHFLASMR4Y_01408 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D SPHFLASMR4Y_01441 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D SPHFLASMR4Y_01409 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D SPHFLASMR4Y_01423 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SPHFLASMR4Y_00594 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D SPHFLASMR4Y_00863 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D SPHFLASMR4Y_01427 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D SPHFLASMR4Y_00926 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D SPHFLASMR4Y_01432 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D SPHFLASMR4Y_02755 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D SPHFLASMR4Y_01972 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D SPHFLASMR4Y_01999 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D SPHFLASMR4Y_01433 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D SPHFLASMR4Y_01436 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D SPHFLASMR4Y_01435 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D SPHFLASMR4Y_01424 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D SPHFLASMR4Y_01421 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D SPHFLASMR4Y_02003 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D SPHFLASMR4Y_00927 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D SPHFLASMR4Y_02002 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D SPHFLASMR4Y_01998 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D SPHFLASMR4Y_02202 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D SPHFLASMR4Y_01426 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D SPHFLASMR4Y_01417 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D SPHFLASMR4Y_01429 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D SPHFLASMR4Y_01406 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D SPHFLASMR4Y_01420 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D SPHFLASMR4Y_00859 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D SPHFLASMR4Y_02404 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D SPHFLASMR4Y_02040 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D SPHFLASMR4Y_01431 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D SPHFLASMR4Y_01434 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D SPHFLASMR4Y_01425 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D SPHFLASMR4Y_00937 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D SPHFLASMR4Y_02041 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D SPHFLASMR4Y_01963 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D SPHFLASMR4Y_01428 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D SPHFLASMR4Y_01418 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D SPHFLASMR4Y_01288 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D SPHFLASMR4Y_02782 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D SPHFLASMR4Y_02242 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D SPHFLASMR4Y_02405 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D SPHFLASMR4Y_01478 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D SPHFLASMR4Y_01475 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D SPHFLASMR4Y_01474 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:sfla00970]
D SPHFLASMR4Y_01476 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SPHFLASMR4Y_03258 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SPHFLASMR4Y_01484 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SPHFLASMR4Y_00207 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_01002 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_02725 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_00929 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_01054 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D SPHFLASMR4Y_01137 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D SPHFLASMR4Y_03162 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D SPHFLASMR4Y_02898 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SPHFLASMR4Y_00535 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SPHFLASMR4Y_02880 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D SPHFLASMR4Y_00747 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SPHFLASMR4Y_01560 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SPHFLASMR4Y_01280 tRNA-His K14226 tRNA-His; tRNA His
D SPHFLASMR4Y_01477 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D SPHFLASMR4Y_01485 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D SPHFLASMR4Y_00675 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_02385 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_00897 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_03251 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_02536 tRNA-Ser K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_00434 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SPHFLASMR4Y_00948 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SPHFLASMR4Y_01006 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_01473 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_00996 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_01481 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_03095 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D SPHFLASMR4Y_01373 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SPHFLASMR4Y_01146 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SPHFLASMR4Y_01005 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SPHFLASMR4Y_00784 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_02417 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_02224 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_01161 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_01763 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SPHFLASMR4Y_02086 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SPHFLASMR4Y_00678 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SPHFLASMR4Y_01992 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D SPHFLASMR4Y_01621 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D SPHFLASMR4Y_02758 tRNA-Val K14237 tRNA-Val; tRNA Val
D SPHFLASMR4Y_02786 tRNA-Val K14237 tRNA-Val; tRNA Val
D SPHFLASMR4Y_01096 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_02411 gltX1; glutamate--tRNA ligase 1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_00899 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SPHFLASMR4Y_00898 gatB; aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D SPHFLASMR4Y_00900 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D SPHFLASMR4Y_01307 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SPHFLASMR4Y_01320 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SPHFLASMR4Y_00932 glyQ; glycine--tRNA ligase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D SPHFLASMR4Y_00931 glyS; glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D SPHFLASMR4Y_03198 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SPHFLASMR4Y_03018 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SPHFLASMR4Y_00013 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SPHFLASMR4Y_00778 ileS; isoleucine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SPHFLASMR4Y_00977 purU; formyltetrahydrofolate deformylase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D SPHFLASMR4Y_03156 ileS; isoleucine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SPHFLASMR4Y_02276 ileS; isoleucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SPHFLASMR4Y_01537 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SPHFLASMR4Y_02633 lysK; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D SPHFLASMR4Y_00063 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SPHFLASMR4Y_00810 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SPHFLASMR4Y_02479 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SPHFLASMR4Y_02403 pheS; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SPHFLASMR4Y_02402 pheT; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SPHFLASMR4Y_01046 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SPHFLASMR4Y_02495 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:sfla03060]
D SPHFLASMR4Y_01416 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D SPHFLASMR4Y_01996 preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D SPHFLASMR4Y_01078 preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D SPHFLASMR4Y_01371 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D SPHFLASMR4Y_01370 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D SPHFLASMR4Y_01372 preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D SPHFLASMR4Y_02504 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SPHFLASMR4Y_01057 preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SPHFLASMR4Y_02497 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D SPHFLASMR4Y_00864 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SPHFLASMR4Y_00957 bacterial small SRP K01983 ffs; SRP RNA
D SPHFLASMR4Y_00868 ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D SPHFLASMR4Y_00068 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D SPHFLASMR4Y_00069 tatB; Sec-independent protein translocase protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D SPHFLASMR4Y_00070 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
D SPHFLASMR4Y_00823 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SPHFLASMR4Y_03040 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SPHFLASMR4Y_01538 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:sfla04122]
D SPHFLASMR4Y_00959 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_00960 iscS; IscS-like cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_01839 sseA; 3-mercaptopyruvate sulfurtransferase K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SPHFLASMR4Y_02078 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D SPHFLASMR4Y_00706 moaE; molybdopterin synthase catalytic subunit K03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]
D SPHFLASMR4Y_01052 moaA; cyclic pyranopterin phosphate synthase K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D SPHFLASMR4Y_00705 moaD; molybdopterin synthase sulfur carrier subunit K03636 moaD; sulfur-carrier protein
D SPHFLASMR4Y_02747 moeB; molybdopterin-synthase adenylyltransferase K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D SPHFLASMR4Y_01089 moaC; cyclic pyranopterin monophosphate synthase accessory protein K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D SPHFLASMR4Y_01068 moaB; molybdenum cofactor biosynthesis protein B K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
C 03050 Proteasome
C 03018 RNA degradation [PATH:sfla03018]
D SPHFLASMR4Y_01240 rppH; RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
D SPHFLASMR4Y_00541 rne; ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D SPHFLASMR4Y_01025 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SPHFLASMR4Y_00595 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D SPHFLASMR4Y_00270 rhlE; ATP-dependent RNA helicase RhlE K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D SPHFLASMR4Y_00809 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D SPHFLASMR4Y_03262 deaD; ATP-dependent RNA helicase DeaD K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D SPHFLASMR4Y_03391 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D SPHFLASMR4Y_02299 fliI; ATP synthase K03628 rho; transcription termination factor Rho
D SPHFLASMR4Y_01104 rnjA; ribonuclease J1 K12574 rnj; ribonuclease J [EC:3.1.-.-]
D SPHFLASMR4Y_00173 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D SPHFLASMR4Y_02177 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SPHFLASMR4Y_00772 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D SPHFLASMR4Y_01327 ppk; polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D SPHFLASMR4Y_02847 cca; CCA-adding enzyme K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:sfla03030]
D SPHFLASMR4Y_02292 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SPHFLASMR4Y_01071 dnaE2; DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SPHFLASMR4Y_00956 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SPHFLASMR4Y_00779 dnaX; DNA polymerase III subunit tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SPHFLASMR4Y_02278 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SPHFLASMR4Y_01338 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D SPHFLASMR4Y_00573 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SPHFLASMR4Y_00658 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D SPHFLASMR4Y_01037 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D SPHFLASMR4Y_00366 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_03338 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_00059 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D SPHFLASMR4Y_00638 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D SPHFLASMR4Y_02166 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SPHFLASMR4Y_00600 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:sfla03410]
D SPHFLASMR4Y_01916 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SPHFLASMR4Y_02727 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SPHFLASMR4Y_00514 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_03284 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D SPHFLASMR4Y_02754 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D SPHFLASMR4Y_01625 alkA; DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D SPHFLASMR4Y_02854 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D SPHFLASMR4Y_00845 Uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_01252 Uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_03357 DNA polymerase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_01876 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SPHFLASMR4Y_03342 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SPHFLASMR4Y_02166 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SPHFLASMR4Y_02881 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SPHFLASMR4Y_00600 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:sfla03420]
D SPHFLASMR4Y_01050 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D SPHFLASMR4Y_03077 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D SPHFLASMR4Y_03310 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D SPHFLASMR4Y_01184 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D SPHFLASMR4Y_01213 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D SPHFLASMR4Y_02166 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SPHFLASMR4Y_00600 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:sfla03430]
D SPHFLASMR4Y_01577 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D SPHFLASMR4Y_00942 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D SPHFLASMR4Y_01213 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D SPHFLASMR4Y_03364 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D SPHFLASMR4Y_01894 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D SPHFLASMR4Y_02881 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SPHFLASMR4Y_00366 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_03338 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_01071 dnaE2; DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SPHFLASMR4Y_00573 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SPHFLASMR4Y_00956 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SPHFLASMR4Y_02278 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SPHFLASMR4Y_00779 dnaX; DNA polymerase III subunit tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SPHFLASMR4Y_02292 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SPHFLASMR4Y_01338 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D SPHFLASMR4Y_00600 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:sfla03440]
D SPHFLASMR4Y_02881 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SPHFLASMR4Y_00366 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_03338 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_01461 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D SPHFLASMR4Y_01181 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D SPHFLASMR4Y_00976 recR; recombination protein RecR K06187 recR; recombination protein RecR
D SPHFLASMR4Y_01310 recombinase A K03553 recA; recombination protein RecA
D SPHFLASMR4Y_02166 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SPHFLASMR4Y_02211 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D SPHFLASMR4Y_02210 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D SPHFLASMR4Y_02212 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D SPHFLASMR4Y_01048 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D SPHFLASMR4Y_01071 dnaE2; DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SPHFLASMR4Y_00573 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SPHFLASMR4Y_00956 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SPHFLASMR4Y_02278 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SPHFLASMR4Y_00779 dnaX; DNA polymerase III subunit tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SPHFLASMR4Y_02292 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SPHFLASMR4Y_01338 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D SPHFLASMR4Y_00141 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:sfla02010]
D SPHFLASMR4Y_02540 nrtA; nitrate transport protein NrtA K15576 nrtA; nitrate/nitrite transport system substrate-binding protein
D SPHFLASMR4Y_02541 cmpB; bicarbonate transport system permease protein CmpB K15577 nrtB; nitrate/nitrite transport system permease protein
D SPHFLASMR4Y_02542 glnQ; glutamine ABC transporter ATP-binding protein K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4]
D SPHFLASMR4Y_01628 opuBB; choline transport system permease protein OpuBB K05845 opuC; osmoprotectant transport system substrate-binding protein
D SPHFLASMR4Y_01629 glnQ; arginine ABC transporter ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D SPHFLASMR4Y_01587 MlaD protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D SPHFLASMR4Y_01589 mlaE; putative phospholipid ABC transporter permease protein MlaE K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D SPHFLASMR4Y_01588 glnQ; glutamine ABC transporter ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D SPHFLASMR4Y_00715 pstS; phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D SPHFLASMR4Y_00545 pstS; phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D SPHFLASMR4Y_00714 pstC1; phosphate transport system permease protein PstC 1 K02037 pstC; phosphate transport system permease protein
D SPHFLASMR4Y_00713 pstA; phosphate transport system permease protein PstA K02038 pstA; phosphate transport system permease protein
D SPHFLASMR4Y_00712 glnQ; glutamine ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SPHFLASMR4Y_03249 oppA; periplasmic oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SPHFLASMR4Y_01845 oppB; oligopeptide transport system permease protein OppB K15581 oppB; oligopeptide transport system permease protein
D SPHFLASMR4Y_01844 oppC; oligopeptide transport system permease protein OppC K15582 oppC; oligopeptide transport system permease protein
D SPHFLASMR4Y_01843 glnQ; glutamine ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SPHFLASMR4Y_01074 lolE; lipoprotein-releasing system transmembrane protein LolE K09808 lolC_E; lipoprotein-releasing system permease protein
D SPHFLASMR4Y_01073 glnQ; glutamine ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D SPHFLASMR4Y_01273 ccmC; heme exporter protein C K02195 ccmC; heme exporter protein C
D SPHFLASMR4Y_01633 ccmB; heme exporter protein B K02194 ccmB; heme exporter protein B
D SPHFLASMR4Y_01632 ccmA; cytochrome c biogenesis ATP-binding export protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D SPHFLASMR4Y_01872 putative permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein
D SPHFLASMR4Y_01873 lptG; lipopolysaccharide export system permease protein LptG K11720 lptG; lipopolysaccharide export system permease protein
D SPHFLASMR4Y_02232 glnQ; glutamine ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D SPHFLASMR4Y_00296 glnQ; glutamine ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D SPHFLASMR4Y_02389 cell division ABC transporter subunit FtsX K09811 ftsX; cell division transport system permease protein
D SPHFLASMR4Y_02388 glnQ; glutamine ABC transporter ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D SPHFLASMR4Y_03392 glnQ; glutamine ABC transporter ATP-binding protein K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter
D SPHFLASMR4Y_01664 glnQ; glutamine ABC transporter ATP-binding protein K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB
C 02060 Phosphotransferase system (PTS) [PATH:sfla02060]
D SPHFLASMR4Y_00970 ptsO; phosphocarrier protein NPr K02784 ptsH; phosphocarrier protein HPr
D SPHFLASMR4Y_00969 manX; PTS system mannose-specific EIIAB component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SPHFLASMR4Y_03330 ptsI; phosphoenolpyruvate-protein phosphotransferase K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9]
D SPHFLASMR4Y_02290 ptsN; nitrogen regulatory protein K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
C 03070 Bacterial secretion system [PATH:sfla03070]
D SPHFLASMR4Y_03160 bepC; outer membrane efflux protein BepC K12340 tolC; outer membrane protein
D SPHFLASMR4Y_03066 xcpQ; type II secretion system protein D K02453 gspD; general secretion pathway protein D
D SPHFLASMR4Y_03065 epsC; type II secretion system protein C K02452 gspC; general secretion pathway protein C
D SPHFLASMR4Y_03068 epsF; type II secretion system protein F K02455 gspF; general secretion pathway protein F
D SPHFLASMR4Y_03069 xcpT; type II secretion system protein G K02456 gspG; general secretion pathway protein G
D SPHFLASMR4Y_02669 type II secretion system protein GspH K02457 gspH; general secretion pathway protein H
D SPHFLASMR4Y_02670 type II secretion system (T2SS), protein I K02458 gspI; general secretion pathway protein I
D SPHFLASMR4Y_01282 xcpW; type II secretion system protein J K02459 gspJ; general secretion pathway protein J
D SPHFLASMR4Y_01281 gspK; putative type II secretion system protein K K02460 gspK; general secretion pathway protein K
D SPHFLASMR4Y_03071 type II secretion system (T2SS), protein M K02462 gspM; general secretion pathway protein M
D SPHFLASMR4Y_03067 epsE; type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
D SPHFLASMR4Y_03166 epsE; type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
D SPHFLASMR4Y_01371 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D SPHFLASMR4Y_01370 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D SPHFLASMR4Y_01996 preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D SPHFLASMR4Y_01078 preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D SPHFLASMR4Y_01416 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D SPHFLASMR4Y_01372 preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D SPHFLASMR4Y_02504 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SPHFLASMR4Y_01057 preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SPHFLASMR4Y_00868 ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D SPHFLASMR4Y_02497 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D SPHFLASMR4Y_00864 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SPHFLASMR4Y_00068 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D SPHFLASMR4Y_00069 tatB; Sec-independent protein translocase protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D SPHFLASMR4Y_00070 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:sfla02020]
D SPHFLASMR4Y_00716 phoR; alkaline phosphatase synthesis sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D SPHFLASMR4Y_00710 fixJ; DNA-binding response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D SPHFLASMR4Y_03139 pld; phospholipase D K01113 phoD; alkaline phosphatase D [EC:3.1.3.1]
D SPHFLASMR4Y_00715 pstS; phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D SPHFLASMR4Y_00545 pstS; phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D SPHFLASMR4Y_01833 degP; periplasmic serine endoprotease DegP K04771 degP; serine protease Do [EC:3.4.21.107]
D SPHFLASMR4Y_02927 cusF; cation efflux system protein CusF K07810 cusF; Cu(I)/Ag(I) efflux system periplasmic protein CusF
D SPHFLASMR4Y_02925 cusB; cation efflux system protein CusB K07798 cusB; membrane fusion protein, copper/silver efflux system
D SPHFLASMR4Y_02926 cusA; cation efflux system protein CusA K07787 cusA; copper/silver efflux system protein
D SPHFLASMR4Y_00231 lafS; RNA polymerase sigma factor for flagellar operon K02405 fliA; RNA polymerase sigma factor FliA
D SPHFLASMR4Y_02876 kdpD; sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D SPHFLASMR4Y_02875 fixJ; DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D SPHFLASMR4Y_02203 ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D SPHFLASMR4Y_02757 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D SPHFLASMR4Y_00966 baeS; signal transduction histidine-protein kinase BaeS K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
D SPHFLASMR4Y_00965 fixJ; DNA-binding response regulator K14981 chvI; two-component system, OmpR family, response regulator ChvI
D SPHFLASMR4Y_00273 mcl2; (3S)-malyl-CoA thioesterase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D SPHFLASMR4Y_02054 fixJ; DNA-binding response regulator K08083 algR; two-component system, LytTR family, response regulator AlgR
D SPHFLASMR4Y_01958 ampC; beta-lactamase K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D SPHFLASMR4Y_01555 spore Coat Protein U domain protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D SPHFLASMR4Y_01556 putative fimbrial chaperone protein K07346 fimC; fimbrial chaperone protein
D SPHFLASMR4Y_01557 caf1A; F1 capsule-anchoring protein K07347 fimD; outer membrane usher protein
D SPHFLASMR4Y_01683 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00199 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00200 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00054 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D SPHFLASMR4Y_01682 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D SPHFLASMR4Y_00053 xpsD; type II secretion system protein D K02280 cpaC; pilus assembly protein CpaC
D SPHFLASMR4Y_01681 pulD; type II secretion system protein D K02280 cpaC; pilus assembly protein CpaC
D SPHFLASMR4Y_00051 iron-sulfur cluster carrier protein K02282 cpaE; pilus assembly protein CpaE
D SPHFLASMR4Y_01676 AAA domain protein K02282 cpaE; pilus assembly protein CpaE
D SPHFLASMR4Y_00129 putative conjugal transfer protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D SPHFLASMR4Y_01675 putative conjugal transfer protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D SPHFLASMR4Y_00050 type II secretion system (T2SS), protein F K12510 tadB; tight adherence protein B
D SPHFLASMR4Y_01674 type II secretion system (T2SS), protein F K12510 tadB; tight adherence protein B
D SPHFLASMR4Y_00049 type II secretion system (T2SS), protein F K12511 tadC; tight adherence protein C
D SPHFLASMR4Y_01673 type II secretion system (T2SS), protein F K12511 tadC; tight adherence protein C
D SPHFLASMR4Y_01582 glnD; bifunctional uridylyltransferase/uridylyl-removing enzyme K00990 glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59]
D SPHFLASMR4Y_01515 glnB; nitrogen regulatory protein P-II K04751 glnB; nitrogen regulatory protein P-II 1
D SPHFLASMR4Y_00768 glnL; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
D SPHFLASMR4Y_00769 fixJ; DNA-binding response regulator K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
D SPHFLASMR4Y_01516 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SPHFLASMR4Y_00770 kinB; alginate biosynthesis sensor protein KinB K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D SPHFLASMR4Y_00771 fixJ; DNA-binding response regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02231 rpoN2; RNA polymerase sigma-54 factor 2 K03092 rpoN; RNA polymerase sigma-54 factor
D SPHFLASMR4Y_02243 fixJ; DNA-binding response regulator K11443 divK; two-component system, cell cycle response regulator DivK
D SPHFLASMR4Y_01311 fixJ; DNA-binding response regulator K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
D SPHFLASMR4Y_00888 histidine phosphotransferase K13588 chpT; histidine phosphotransferase ChpT
D SPHFLASMR4Y_00652 fixJ; DNA-binding response regulator K13584 ctrA; two-component system, cell cycle response regulator CtrA
D SPHFLASMR4Y_02787 fixJ; DNA-binding response regulator K13589 cpdR; two-component system, cell cycle response regulator CpdR
D SPHFLASMR4Y_00408 luxR; HTH-type transcriptional regulator LuxR K10913 hapR; TetR/AcrR family transcriptional regulator, hemagglutinin/protease regulatory protein
D SPHFLASMR4Y_00245 fixL; sensor protein FixL K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
D SPHFLASMR4Y_00246 fixJ; DNA-binding response regulator K14987 fixJ; two-component system, LuxR family, response regulator FixJ
D SPHFLASMR4Y_00233 zraR; transcriptional regulatory protein ZraR K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein
D SPHFLASMR4Y_01148 rpfC; sensory/regulatory protein RpfC K10715 rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
D SPHFLASMR4Y_00602 glxR; CRP-like cAMP-activated global transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_01076 crp; CRP-like cAMP-activated global transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_02449 transcriptional activator FtrB K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_01149 paaF; 2,3-dehydroadipyl-CoA hydratase K13816 rpfF; DSF synthase
D SPHFLASMR4Y_03059 glsA; thermolabile glutaminase K01425 glsA; glutaminase [EC:3.5.1.2]
D SPHFLASMR4Y_00742 petA; ubiquinol-cytochrome c reductase iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D SPHFLASMR4Y_00743 petB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D SPHFLASMR4Y_00744 petC; cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D SPHFLASMR4Y_02057 cycM; cytochrome c-552 K08738 CYC; cytochrome c
D SPHFLASMR4Y_02601 cycM; cytochrome c-552 K08738 CYC; cytochrome c
D SPHFLASMR4Y_02332 cytochrome c-550 K08738 CYC; cytochrome c
D SPHFLASMR4Y_02855 cytochrome c2 K08738 CYC; cytochrome c
D SPHFLASMR4Y_00255 peptidase S41 K00404 ccoN; cytochrome c oxidase cbb3-type subunit I [EC:7.1.1.9]
D SPHFLASMR4Y_00254 cytochrome C oxidase, mono-heme subunit/FixO K00405 ccoO; cytochrome c oxidase cbb3-type subunit II
D SPHFLASMR4Y_00253 Cbb3-type cytochrome oxidase component FixQ K00407 ccoQ; cytochrome c oxidase cbb3-type subunit IV
D SPHFLASMR4Y_00252 ccoP; Cbb3-type cytochrome c oxidase subunit CcoP K00406 ccoP; cytochrome c oxidase cbb3-type subunit III
D SPHFLASMR4Y_02163 cydA; cytochrome bd-I ubiquinol oxidase subunit 1 K00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]
D SPHFLASMR4Y_02164 appB; cytochrome bd-II ubiquinol oxidase subunit 2 K00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]
D SPHFLASMR4Y_03160 bepC; outer membrane efflux protein BepC K12340 tolC; outer membrane protein
D SPHFLASMR4Y_00987 polysaccharide biosynthesis/export protein K01991 wza; polysaccharide biosynthesis/export protein
D SPHFLASMR4Y_02419 polysaccharide biosynthesis/export protein K01991 wza; polysaccharide biosynthesis/export protein
D SPHFLASMR4Y_00437 yfkJ; low molecular weight protein-tyrosine-phosphatase YfkJ K25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]
D SPHFLASMR4Y_00280 wecB; UDP-N-acetylglucosamine 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D SPHFLASMR4Y_02426 wbpI; UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimerase K01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]
D SPHFLASMR4Y_00279 wecC; UDP-N-acetyl-D-mannosamine dehydrogenase K02472 wecC; UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase [EC:1.1.1.336]
D SPHFLASMR4Y_03124 fec operon regulator FecR K07165 fecR; transmembrane sensor
D SPHFLASMR4Y_01907 histidine phosphotransferase K20976 hptB; histidine phosphotransfer protein HptB
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis [PATH:sfla04148]
D SPHFLASMR4Y_00834 ldc; lysine/ornithine decarboxylase K01581 E4.1.1.17; ornithine decarboxylase [EC:4.1.1.17]
D SPHFLASMR4Y_00742 petA; ubiquinol-cytochrome c reductase iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:sfla02024]
D SPHFLASMR4Y_00772 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D SPHFLASMR4Y_00408 luxR; HTH-type transcriptional regulator LuxR K10913 hapR; TetR/AcrR family transcriptional regulator, hemagglutinin/protease regulatory protein
D SPHFLASMR4Y_01081 trpE; anthranilate synthase component 1 K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D SPHFLASMR4Y_01086 guaA; GMP synthetase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D SPHFLASMR4Y_03007 aroH; phospho-2-dehydro-3-deoxyheptonate aldolase K01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D SPHFLASMR4Y_02875 fixJ; DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D SPHFLASMR4Y_01149 paaF; 2,3-dehydroadipyl-CoA hydratase K13816 rpfF; DSF synthase
D SPHFLASMR4Y_01667 T1SS_rpt_143: T1SS-143 repeat domain protein K20276 bapA; large repetitive protein
D SPHFLASMR4Y_02962 prpE; propionate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00456 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02365 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02372 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_03215 prpE; acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_01148 rpfC; sensory/regulatory protein RpfC K10715 rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
D SPHFLASMR4Y_00602 glxR; CRP-like cAMP-activated global transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_01076 crp; CRP-like cAMP-activated global transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_02449 transcriptional activator FtrB K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_02205 zur; zinc uptake regulation protein K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
D SPHFLASMR4Y_03341 ribA; GTP cyclohydrolase-2 K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D SPHFLASMR4Y_02414 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D SPHFLASMR4Y_00790 ttgI; toluene efflux pump outer membrane protein TtgI K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_01635 oprM; outer membrane protein OprM K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_03249 oppA; periplasmic oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SPHFLASMR4Y_01845 oppB; oligopeptide transport system permease protein OppB K15581 oppB; oligopeptide transport system permease protein
D SPHFLASMR4Y_01844 oppC; oligopeptide transport system permease protein OppC K15582 oppC; oligopeptide transport system permease protein
D SPHFLASMR4Y_01843 glnQ; glutamine ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SPHFLASMR4Y_03248 gsiB; glutathione-binding protein GsiB K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SPHFLASMR4Y_02504 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SPHFLASMR4Y_01996 preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D SPHFLASMR4Y_01078 preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D SPHFLASMR4Y_01416 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D SPHFLASMR4Y_01372 preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D SPHFLASMR4Y_01057 preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SPHFLASMR4Y_00868 ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D SPHFLASMR4Y_02497 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D SPHFLASMR4Y_00864 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly [PATH:sfla02040]
D SPHFLASMR4Y_00230 flhA; flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA
D SPHFLASMR4Y_01039 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D SPHFLASMR4Y_00233 zraR; transcriptional regulatory protein ZraR K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein
D SPHFLASMR4Y_02231 rpoN2; RNA polymerase sigma-54 factor 2 K03092 rpoN; RNA polymerase sigma-54 factor
D SPHFLASMR4Y_00231 lafS; RNA polymerase sigma factor for flagellar operon K02405 fliA; RNA polymerase sigma factor FliA
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D SPHFLASMR4Y_01025 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism [PATH:sfla04980]
D SPHFLASMR4Y_01852 cob(I)yrinic acid a,c-diamide adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D SPHFLASMR4Y_00816 scpA; methylmalonyl-CoA mutase K01847 MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]
D SPHFLASMR4Y_03316 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
D SPHFLASMR4Y_03317 metH; methionine synthase K00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance [PATH:sfla01501]
D SPHFLASMR4Y_00551 muropeptide transporter K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D SPHFLASMR4Y_01208 muropeptide transporter K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D SPHFLASMR4Y_02739 folate-biopterin transporter K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D SPHFLASMR4Y_00065 nagZ; beta-hexosaminidase K01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]
D SPHFLASMR4Y_01958 ampC; beta-lactamase K01467 ampC; beta-lactamase class C [EC:3.5.2.6]
D SPHFLASMR4Y_03249 oppA; periplasmic oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SPHFLASMR4Y_01845 oppB; oligopeptide transport system permease protein OppB K15581 oppB; oligopeptide transport system permease protein
D SPHFLASMR4Y_01844 oppC; oligopeptide transport system permease protein OppC K15582 oppC; oligopeptide transport system permease protein
D SPHFLASMR4Y_01843 glnQ; glutamine ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SPHFLASMR4Y_03235 mecR1; methicillin resistance mecR1 protein K02172 blaR1; bla regulator protein blaR1
D SPHFLASMR4Y_03234 blaI; penicillinase repressor K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
D SPHFLASMR4Y_03323 smeA; carbapenem-hydrolyzing beta-lactamase Sme-1 K17836 penP; beta-lactamase class A [EC:3.5.2.6]
D SPHFLASMR4Y_00788 acrA; multidrug efflux pump subunit AcrA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_02021 mdtA; multidrug resistance protein MdtA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_00789 acrB; multidrug efflux pump subunit AcrB K18138 acrB; multidrug efflux pump
D SPHFLASMR4Y_00790 ttgI; toluene efflux pump outer membrane protein TtgI K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_01635 oprM; outer membrane protein OprM K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_03160 bepC; outer membrane efflux protein BepC K12340 tolC; outer membrane protein
D SPHFLASMR4Y_02281 pbpG; penicillin-binding protein 2D K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00022 pbpF; penicillin-binding protein 1F K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00543 mrcA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00946 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D SPHFLASMR4Y_00083 ftsI; peptidoglycan synthase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D SPHFLASMR4Y_02716 metallo-beta-lactamase L1 type 3 K17837 bla2; metallo-beta-lactamase class B [EC:3.5.2.6]
C 01502 Vancomycin resistance [PATH:sfla01502]
D SPHFLASMR4Y_00093 ddlB; D-alanine--D-alanine ligase B K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SPHFLASMR4Y_00812 alr1; alanine racemase 1 K01775 alr; alanine racemase [EC:5.1.1.1]
D SPHFLASMR4Y_00085 murC; UDP-N-acetylmuramate--L-alanine ligase K01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
D SPHFLASMR4Y_00086 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D SPHFLASMR4Y_00089 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:sfla01503]
D SPHFLASMR4Y_00542 amiC; N-acetylmuramoyl-L-alanine amidase AmiC K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D SPHFLASMR4Y_01833 degP; periplasmic serine endoprotease DegP K04771 degP; serine protease Do [EC:3.4.21.107]
D SPHFLASMR4Y_00788 acrA; multidrug efflux pump subunit AcrA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_02021 mdtA; multidrug resistance protein MdtA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_00789 acrB; multidrug efflux pump subunit AcrB K18138 acrB; multidrug efflux pump
D SPHFLASMR4Y_03160 bepC; outer membrane efflux protein BepC K12340 tolC; outer membrane protein
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:sfla01000]
C 01001 Protein kinases [BR:sfla01001]
D SPHFLASMR4Y_03108 invasion protein regulator K12132 prkC; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1]
D SPHFLASMR4Y_02420 ptk; tyrosine-protein kinase ptk K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]
D SPHFLASMR4Y_00985 yveL; putative tyrosine-protein kinase YveL K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3]
D SPHFLASMR4Y_00716 phoR; alkaline phosphatase synthesis sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D SPHFLASMR4Y_02876 kdpD; sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D SPHFLASMR4Y_00966 baeS; signal transduction histidine-protein kinase BaeS K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
D SPHFLASMR4Y_02053 yehU; sensor histidine kinase YehU K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
D SPHFLASMR4Y_03011 ypdA; sensor histidine kinase YpdA K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
D SPHFLASMR4Y_00768 glnL; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
D SPHFLASMR4Y_00770 kinB; alginate biosynthesis sensor protein KinB K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D SPHFLASMR4Y_01311 fixJ; DNA-binding response regulator K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
D SPHFLASMR4Y_00245 fixL; sensor protein FixL K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
D SPHFLASMR4Y_01148 rpfC; sensory/regulatory protein RpfC K10715 rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:sfla01009]
D SPHFLASMR4Y_00847 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D SPHFLASMR4Y_00909 serB; phosphoserine phosphatase K01079 serB; phosphoserine phosphatase [EC:3.1.3.3]
C 01002 Peptidases and inhibitors [BR:sfla01002]
D SPHFLASMR4Y_01538 lspA; lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
D SPHFLASMR4Y_00674 pppA; leader peptidase PppA K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D SPHFLASMR4Y_00055 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D SPHFLASMR4Y_01670 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D SPHFLASMR4Y_01918 guaA; GMP synthetase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SPHFLASMR4Y_01229 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SPHFLASMR4Y_01471 gltB; ferredoxin-dependent glutamate synthase 1 K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D SPHFLASMR4Y_02531 gltB; glutamate synthase [NADPH] large chain K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
D SPHFLASMR4Y_00724 nodM; glutamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SPHFLASMR4Y_01656 asnO; asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D SPHFLASMR4Y_00979 asnB; asparagine synthetase [glutamine-hydrolyzing] 1 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D SPHFLASMR4Y_00311 asnO; asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
D SPHFLASMR4Y_02696 yraA; putative cysteine protease YraA K05520 yhbO; deglycase [EC:3.5.1.124]
D SPHFLASMR4Y_02170 inhA; isonitrile hydratase K18199 inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103]
D SPHFLASMR4Y_00301 murein L,D-transpeptidase K21470 ycbB; L,D-transpeptidase YcbB
D SPHFLASMR4Y_03381 CAAX protease self-immunity K07052 K07052; CAAX protease family protein
D SPHFLASMR4Y_01856 CAAX protease self-immunity K07052 K07052; CAAX protease family protein
D SPHFLASMR4Y_01601 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
D SPHFLASMR4Y_00851 angiotensin-converting enzyme K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
D SPHFLASMR4Y_01810 dcp; peptidyl-dipeptidase dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
D SPHFLASMR4Y_00697 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-]
D SPHFLASMR4Y_03297 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-]
D SPHFLASMR4Y_01339 pepA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D SPHFLASMR4Y_03035 pepB; peptidase B K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D SPHFLASMR4Y_01535 membrane dipeptidase (peptidase family M19) K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D SPHFLASMR4Y_03371 membrane dipeptidase (peptidase family M19) K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D SPHFLASMR4Y_01345 cpg2; carboxypeptidase G2 K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]
D SPHFLASMR4Y_02501 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D SPHFLASMR4Y_03353 dapE; putative succinyl-diaminopimelate desuccinylase K13049 PM20D1; carboxypeptidase PM20D1 [EC:3.4.17.-]
D SPHFLASMR4Y_01503 map; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D SPHFLASMR4Y_01765 pepE; putative dipeptidase PepE K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D SPHFLASMR4Y_03326 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D SPHFLASMR4Y_01549 protease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D SPHFLASMR4Y_01292 mmpA; metalloprotease MmpA K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D SPHFLASMR4Y_03235 mecR1; methicillin resistance mecR1 protein K02172 blaR1; bla regulator protein blaR1
D SPHFLASMR4Y_00889 peptidase K20110 JAMM1; desampylase [EC:3.4.19.15]
D SPHFLASMR4Y_01833 degP; periplasmic serine endoprotease DegP K04771 degP; serine protease Do [EC:3.4.21.107]
D SPHFLASMR4Y_01167 epr; minor extracellular protease Epr K13277 epr; minor extracellular protease Epr [EC:3.4.21.-]
D SPHFLASMR4Y_01405 prolyl endopeptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
D SPHFLASMR4Y_01766 dapb1; dipeptidyl aminopeptidase BI K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
D SPHFLASMR4Y_00781 dacC; D-alanyl-D-alanine carboxypeptidase DacC K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SPHFLASMR4Y_00894 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D SPHFLASMR4Y_00895 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D SPHFLASMR4Y_00954 lon; lon protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D SPHFLASMR4Y_01094 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SPHFLASMR4Y_00823 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SPHFLASMR4Y_03040 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D SPHFLASMR4Y_00569 soluble epoxide hydrolase K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
D SPHFLASMR4Y_01152 ytpA; phospholipase YtpA K01054 MGLL; acylglycerol lipase [EC:3.1.1.23]
D SPHFLASMR4Y_02516 ctpB; carboxy-terminal processing protease CtpB K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
D SPHFLASMR4Y_00497 putative CtpA-like serine protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
D SPHFLASMR4Y_02185 sppA; protease 4 K04773 sppA; protease IV [EC:3.4.21.-]
D SPHFLASMR4Y_00285 murein tetrapeptide carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
D SPHFLASMR4Y_02815 caudovirus prohead serine protease K06904 GP4; Escherichia/Staphylococcus phage prohead protease
D SPHFLASMR4Y_00700 hslV; ATP-dependent protease subunit HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
D SPHFLASMR4Y_00258 ywrD; putative gamma-glutamyltransferase YwrD K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_03216 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SPHFLASMR4Y_00461 tldD; peptidase C69 K03592 pmbA; PmbA protein
D SPHFLASMR4Y_03379 tldD; metalloprotease TldD K03568 tldD; TldD protein
D SPHFLASMR4Y_01831 hflC; modulator of FtsH protease HflC K04087 hflC; modulator of FtsH protease HflC
D SPHFLASMR4Y_01830 hflK; modulator of FtsH protease HflK K04088 hflK; modulator of FtsH protease HflK
C 01003 Glycosyltransferases [BR:sfla01003]
D SPHFLASMR4Y_00452 mgtA; GDP-mannose-dependent alpha-mannosyltransferase K27597 K27597; 1,2-diacylglycerol 3-alpha-glucosyltransferase/glucuronosyltransferase [EC:2.4.1.337 2.4.1.-]
D SPHFLASMR4Y_00684 mgtA; GDP-mannose-dependent alpha-mannosyltransferase K12583 mgtA; phosphatidylinositol alpha 1,6-mannosyltransferase [EC:2.4.1.-]
D SPHFLASMR4Y_02775 pimB; GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase K16150 K16150; glycogen synthase [EC:2.4.1.11]
D SPHFLASMR4Y_00892 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28]
D SPHFLASMR4Y_02281 pbpG; penicillin-binding protein 2D K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00022 pbpF; penicillin-binding protein 1F K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00543 mrcA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_01596 gpgS; glucosyl-3-phosphoglycerate synthase K13693 gpgS; glucosyl-3-phosphoglycerate synthase [EC:2.4.1.266]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:sfla01005]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:sfla01011]
D SPHFLASMR4Y_02494 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]
D SPHFLASMR4Y_00092 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D SPHFLASMR4Y_00090 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D SPHFLASMR4Y_00286 murC; UDP-N-acetylmuramate--L-alanine ligase K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]
D SPHFLASMR4Y_00087 murC; UDP-N-acetylmuramate--L-alanine ligase K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]
D SPHFLASMR4Y_00084 murC; UDP-N-acetylmuramate--L-alanine ligase K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]
D SPHFLASMR4Y_00093 ddlB; D-alanine--D-alanine ligase B K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]
D SPHFLASMR4Y_00812 alr1; alanine racemase 1 K01775 alr; alanine racemase [EC:5.1.1.1]
D SPHFLASMR4Y_00829 murI; glutamate racemase K01776 murI; glutamate racemase [EC:5.1.1.3]
D SPHFLASMR4Y_00285 murein tetrapeptide carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
D SPHFLASMR4Y_00086 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]
D SPHFLASMR4Y_00089 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]
D SPHFLASMR4Y_02534 uppP; undecaprenyl-diphosphatase K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SPHFLASMR4Y_02496 murJ; putative lipid II flippase MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D SPHFLASMR4Y_02281 pbpG; penicillin-binding protein 2D K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00022 pbpF; penicillin-binding protein 1F K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00543 mrcA; penicillin-binding protein 1A K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]
D SPHFLASMR4Y_00946 mrdA; penicillin-binding protein 2 K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]
D SPHFLASMR4Y_00083 ftsI; peptidoglycan synthase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D SPHFLASMR4Y_00781 dacC; D-alanyl-D-alanine carboxypeptidase DacC K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D SPHFLASMR4Y_00892 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28]
D SPHFLASMR4Y_00301 murein L,D-transpeptidase K21470 ycbB; L,D-transpeptidase YcbB
D SPHFLASMR4Y_01315 slt; soluble lytic murein transglycosylase K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D SPHFLASMR4Y_00846 slt; soluble lytic murein transglycosylase K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D SPHFLASMR4Y_02499 mltA; membrane-bound lytic murein transglycosylase A K08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29]
D SPHFLASMR4Y_00783 mltB; membrane-bound lytic murein transglycosylase B K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]
D SPHFLASMR4Y_00917 mltG; endolytic murein transglycosylase K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]
D SPHFLASMR4Y_00782 RlpA-like protein K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]
D SPHFLASMR4Y_00542 amiC; N-acetylmuramoyl-L-alanine amidase AmiC K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
C 01004 Lipid biosynthesis proteins [BR:sfla01004]
D SPHFLASMR4Y_00921 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D SPHFLASMR4Y_02784 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase 3 K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D SPHFLASMR4Y_00918 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase 2 K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D SPHFLASMR4Y_00162 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00920 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02590 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02338 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02352 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02353 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_03135 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02655 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_02662 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_00609 benD; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SPHFLASMR4Y_01289 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D SPHFLASMR4Y_02070 fabI; enoyl-[acyl-carrier-protein] reductase [NADH] FabI K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D SPHFLASMR4Y_03268 nitronate monooxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D SPHFLASMR4Y_02524 nitronate monooxygenase K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D SPHFLASMR4Y_00528 arylesterase K10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]
D SPHFLASMR4Y_00792 tesB; acyl-CoA thioesterase 2 K10805 tesB; acyl-CoA thioesterase II [EC:3.1.2.-]
D SPHFLASMR4Y_00805 putative acyl-CoA thioester hydrolase K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]
D SPHFLASMR4Y_01491 putative acyl-CoA thioester hydrolase K10806 yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]
D SPHFLASMR4Y_00639 fatty acid desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
D SPHFLASMR4Y_03072 fatty acid desaturase K00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]
D SPHFLASMR4Y_02846 prpE; propionate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SPHFLASMR4Y_00267 prpE; propionyl-CoA synthetase K01908 ACSS3; propionyl-CoA synthetase [EC:6.2.1.17]
D SPHFLASMR4Y_02962 prpE; propionate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00456 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02365 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02372 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_03215 prpE; acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00152 long-chain-fatty-acid--CoA ligase FadD17 K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
D SPHFLASMR4Y_01979 prpE; acyl-CoA synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
D SPHFLASMR4Y_00339 prpE; propionyl-CoA synthetase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
D SPHFLASMR4Y_01155 plsB; glycerol-3-phosphate acyltransferase K00631 plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]
D SPHFLASMR4Y_02783 plsX; phosphate acyltransferase K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D SPHFLASMR4Y_00828 plsY; glycerol-3-phosphate acyltransferase K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D SPHFLASMR4Y_02391 2-acyl-glycerophospho-ethanolamine acyltransferase K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins [BR:sfla01008]
D SPHFLASMR4Y_00185 metallo-beta-lactamase superfamily protein K05555 actIV; cyclase [EC:4.-.-.-]
D SPHFLASMR4Y_02679 metallo-beta-lactamase superfamily protein K05555 actIV; cyclase [EC:4.-.-.-]
D SPHFLASMR4Y_01451 rppA; 1,3,6,8-tetrahydroxynaphthalene synthase K16167 bpsA; alkylresorcinol/alkylpyrone synthase
D SPHFLASMR4Y_01450 isoprenylcysteine carboxyl methyltransferase (ICMT) family protein K16168 bpsB; methyltransferase
D SPHFLASMR4Y_02798 racX; putative amino-acid racemase K01779 racD; aspartate racemase [EC:5.1.1.13]
C 01006 Prenyltransferases [BR:sfla01006]
D SPHFLASMR4Y_01893 farnesyl diphosphate synthase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D SPHFLASMR4Y_01358 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D SPHFLASMR4Y_01295 ispU; ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) K00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]
D SPHFLASMR4Y_00463 crtB; all-trans-phytoene synthase/15-cis-phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D SPHFLASMR4Y_01018 squalene/phytoene synthase K02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]
D SPHFLASMR4Y_00910 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D SPHFLASMR4Y_03266 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D SPHFLASMR4Y_03046 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:sfla01007]
D SPHFLASMR4Y_02633 lysK; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D SPHFLASMR4Y_01096 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_02411 gltX1; glutamate--tRNA ligase 1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_01854 gltX; glutamate--tRNA ligase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
D SPHFLASMR4Y_01046 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SPHFLASMR4Y_02495 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D SPHFLASMR4Y_00013 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SPHFLASMR4Y_00063 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SPHFLASMR4Y_00778 ileS; isoleucine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SPHFLASMR4Y_01537 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SPHFLASMR4Y_03156 ileS; isoleucine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SPHFLASMR4Y_02276 ileS; isoleucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SPHFLASMR4Y_01320 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SPHFLASMR4Y_02479 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SPHFLASMR4Y_00932 glyQ; glycine--tRNA ligase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D SPHFLASMR4Y_00931 glyS; glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D SPHFLASMR4Y_03018 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SPHFLASMR4Y_00810 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SPHFLASMR4Y_03198 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SPHFLASMR4Y_01307 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SPHFLASMR4Y_02403 pheS; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SPHFLASMR4Y_02402 pheT; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SPHFLASMR4Y_03190 aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SPHFLASMR4Y_03141 alaC; glutamate-pyruvate aminotransferase AlaC K14261 alaC; alanine-synthesizing transaminase [EC:2.6.1.-]
D SPHFLASMR4Y_02397 pat; putative phenylalanine aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SPHFLASMR4Y_00830 hemA; 5-aminolevulinate synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D SPHFLASMR4Y_01866 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D SPHFLASMR4Y_02268 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D SPHFLASMR4Y_00730 astC; succinylornithine transaminase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D SPHFLASMR4Y_02270 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D SPHFLASMR4Y_01364 dat; D-alanine aminotransferase K00824 dat; D-alanine transaminase [EC:2.6.1.21]
D SPHFLASMR4Y_02897 ilvE; branched-chain-amino-acid aminotransferase K00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]
D SPHFLASMR4Y_03175 pabB; aminodeoxychorismate synthase component 1 K03342 pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]
D SPHFLASMR4Y_02062 serC; phosphoserine aminotransferase K00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]
C 00199 Cytochrome P450 [BR:sfla00199]
D SPHFLASMR4Y_02994 cytochrome p450 CYP199A2 K22553 CYP199A2; 4-methoxybenzoate monooxygenase (O-demethylating) [EC:1.14.99.15]
C 00194 Photosynthesis proteins [BR:sfla00194]
D SPHFLASMR4Y_00133 atpC; ATP synthase F0F1 subunit epsilon K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D SPHFLASMR4Y_00134 fliI; flagellum-specific ATP synthase FliL K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D SPHFLASMR4Y_00135 atpG; ATP synthase gamma chain K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D SPHFLASMR4Y_00136 fliI; flagellar protein export ATPase FliI K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D SPHFLASMR4Y_00137 atpH; ATP synthase subunit delta K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D SPHFLASMR4Y_01185 atpF; ATP synthase subunit b K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D SPHFLASMR4Y_01186 atpG; ATP synthase subunit b' K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D SPHFLASMR4Y_01187 atpE; ATP synthase subunit c K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D SPHFLASMR4Y_01188 atpB; ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D SPHFLASMR4Y_01189 putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 atpI; ATP synthase protein I
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:sfla03000]
D SPHFLASMR4Y_01499 hpaIIM; modification methylase HpaII K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SPHFLASMR4Y_00139 ada; bifunctional transcriptional activator/DNA repair enzyme Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SPHFLASMR4Y_03292 gcvA; glycine cleavage system transcriptional activator K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D SPHFLASMR4Y_00110 gcvA; glycine cleavage system transcriptional activator K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D SPHFLASMR4Y_00707 cysB; CysB family transcriptional regulator K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator
D SPHFLASMR4Y_01985 cysB; transcriptional regulator CysB K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator
D SPHFLASMR4Y_03001 nodD2; nodulation protein D 2 K14657 nodD; LysR family transcriptional regulator, nod-box dependent transcriptional activator
D SPHFLASMR4Y_02984 cysB; transcriptional regulator CysB K16516 galR; LysR family transcriptional regulator, regulator for genes of the gallate degradation pathway
D SPHFLASMR4Y_00430 lutR; HTH-type transcriptional regulator LutR K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
D SPHFLASMR4Y_00324 DNA-binding transcriptional regulator CsiR K15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator
D SPHFLASMR4Y_00408 luxR; HTH-type transcriptional regulator LuxR K10913 hapR; TetR/AcrR family transcriptional regulator, hemagglutinin/protease regulatory protein
D SPHFLASMR4Y_02320 fadR; fatty acid metabolism regulator protein K13770 ysiA; TetR/AcrR family transcriptional regulator, fatty acid metabolism regulator protein
D SPHFLASMR4Y_00447 acuR; transcriptional regulator AcuR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D SPHFLASMR4Y_02840 nemR; HTH-type transcriptional repressor NemR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D SPHFLASMR4Y_01634 DNA-binding transcriptional repressor AcrR K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
D SPHFLASMR4Y_01495 fadR; fatty acid metabolism regulator protein K18905 ameR; TetR/AcrR family transcriptional regulator, repressor of the ameABC operon
D SPHFLASMR4Y_02966 putative DNA-binding transcriptional regulator K23777 cecR; TetR/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity
D SPHFLASMR4Y_02687 lrp; leucine-responsive regulatory protein K05800 decR; Lrp/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator
D SPHFLASMR4Y_02570 csgD; CsgBAC operon transcriptional regulatory protein K03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein
D SPHFLASMR4Y_00415 slyA; transcriptional regulator SlyA K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
D SPHFLASMR4Y_03113 slyA; transcriptional regulator SlyA K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
D SPHFLASMR4Y_02921 merR1; mercuric resistance operon regulatory protein K08365 merR; MerR family transcriptional regulator, mercuric resistance operon regulatory protein
D SPHFLASMR4Y_03273 soxR; redox-sensitive transcriptional activator SoxR K13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR
D SPHFLASMR4Y_00691 fur; ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D SPHFLASMR4Y_02205 zur; zinc uptake regulation protein K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
D SPHFLASMR4Y_02615 DNA-binding transcriptional activator MhpR K05818 mhpR; IclR family transcriptional regulator, mhp operon transcriptional activator
D SPHFLASMR4Y_02369 kdgR; transcriptional regulator KdgR K19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor
D SPHFLASMR4Y_00602 glxR; CRP-like cAMP-activated global transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_01076 crp; CRP-like cAMP-activated global transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_02449 transcriptional activator FtrB K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D SPHFLASMR4Y_01642 nsrR; HTH-type transcriptional repressor NsrR K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor
D SPHFLASMR4Y_02705 hlyU; transcriptional activator HlyU K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D SPHFLASMR4Y_00623 ramB; HTH-type transcriptional regulator RamB K07110 ramB; XRE family transcriptional regulator, fatty acid utilization regulator
D SPHFLASMR4Y_03234 blaI; penicillinase repressor K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
D SPHFLASMR4Y_01106 birA; bifunctional ligase/repressor BirA K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D SPHFLASMR4Y_00233 zraR; transcriptional regulatory protein ZraR K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein
D SPHFLASMR4Y_03242 putative transcriptional regulator K07726 K07726; putative transcriptional regulator
D SPHFLASMR4Y_01091 Cro/C1-type HTH DNA-binding domain protein K07727 K07727; putative transcriptional regulator
D SPHFLASMR4Y_03201 transcriptional regulator K07729 K07729; putative transcriptional regulator
D SPHFLASMR4Y_01333 putA; bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D SPHFLASMR4Y_00118 csoR; copper-sensing transcriptional repressor CsoR K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D SPHFLASMR4Y_02945 csoR; copper-sensing transcriptional repressor CsoR K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D SPHFLASMR4Y_00026 bolA; DNA-binding transcriptional regulator BolA K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D SPHFLASMR4Y_02308 parB; chromosome-partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D SPHFLASMR4Y_00358 spo0C; chromosome-partitioning protein Spo0J K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D SPHFLASMR4Y_02031 carD; RNA polymerase-binding transcription factor CarD K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D SPHFLASMR4Y_00157 hrcA; heat-inducible transcriptional repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor
D SPHFLASMR4Y_00872 pspF; Psp operon transcriptional activator K03974 pspF; psp operon transcriptional activator
D SPHFLASMR4Y_00876 DNA-binding transcriptional activator PspC K03973 pspC; phage shock protein C
D SPHFLASMR4Y_01459 DNA-binding transcriptional activator PspC K03973 pspC; phage shock protein C
D SPHFLASMR4Y_01822 paiB; protease synthase and sporulation protein PAI 2 K07734 paiB; transcriptional regulator
D SPHFLASMR4Y_00848 hypothetical protein K07735 algH; putative transcriptional regulator
D SPHFLASMR4Y_03015 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D SPHFLASMR4Y_03305 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D SPHFLASMR4Y_01263 nrdR; transcriptional repressor NrdR K07738 nrdR; transcriptional repressor NrdR
D SPHFLASMR4Y_00080 cell division protein MraZ K03925 mraZ; transcriptional regulator MraZ
C 03021 Transcription machinery [BR:sfla03021]
D SPHFLASMR4Y_01407 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D SPHFLASMR4Y_02009 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D SPHFLASMR4Y_02010 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D SPHFLASMR4Y_03325 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D SPHFLASMR4Y_01039 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D SPHFLASMR4Y_02951 cnrH; RNA polymerase sigma factor CnrH K24073 cnrH; RNA polymerase sigma factor CnrH
D SPHFLASMR4Y_00891 rpoH; RNA polymerase sigma factor RpoH K03089 rpoH; RNA polymerase sigma-32 factor
D SPHFLASMR4Y_02231 rpoN2; RNA polymerase sigma-54 factor 2 K03092 rpoN; RNA polymerase sigma-54 factor
D SPHFLASMR4Y_00231 lafS; RNA polymerase sigma factor for flagellar operon K02405 fliA; RNA polymerase sigma factor FliA
D SPHFLASMR4Y_00586 hypothetical protein K02600 nusA; transcription termination/antitermination protein NusA
D SPHFLASMR4Y_00033 transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB
D SPHFLASMR4Y_01997 hypothetical protein K02601 nusG; transcription termination/antitermination protein NusG
D SPHFLASMR4Y_03015 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D SPHFLASMR4Y_03305 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D SPHFLASMR4Y_01032 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D SPHFLASMR4Y_02299 fliI; ATP synthase K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:sfla03019]
D SPHFLASMR4Y_03294 ftsH3; ATP-dependent zinc metalloprotease FtsH 3 K13525 VCP; transitional endoplasmic reticulum ATPase
D SPHFLASMR4Y_00541 rne; ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D SPHFLASMR4Y_00824 rnc; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D SPHFLASMR4Y_01104 rnjA; ribonuclease J1 K12574 rnj; ribonuclease J [EC:3.1.-.-]
D SPHFLASMR4Y_00809 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D SPHFLASMR4Y_00270 rhlE; ATP-dependent RNA helicase RhlE K11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]
D SPHFLASMR4Y_03262 deaD; ATP-dependent RNA helicase DeaD K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D SPHFLASMR4Y_03391 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D SPHFLASMR4Y_01025 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SPHFLASMR4Y_00595 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D SPHFLASMR4Y_02299 fliI; ATP synthase K03628 rho; transcription termination factor Rho
D SPHFLASMR4Y_00173 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D SPHFLASMR4Y_02177 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SPHFLASMR4Y_00772 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D SPHFLASMR4Y_01327 ppk; polyphosphate kinase K00937 ppk1; polyphosphate kinase [EC:2.7.4.1]
D SPHFLASMR4Y_02847 cca; CCA-adding enzyme K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
D SPHFLASMR4Y_01240 rppH; RNA pyrophosphohydrolase K08311 nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]
D SPHFLASMR4Y_00968 nucleotide-binding protein K06958 rapZ; RNase adapter protein RapZ
C 03041 Spliceosome
C 03011 Ribosome [BR:sfla03011]
D SPHFLASMR4Y_03253 rpsA; 30S ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D SPHFLASMR4Y_01299 rpsB; 30S ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D SPHFLASMR4Y_01430 rpsC; 30S ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D SPHFLASMR4Y_01259 rpsD; 30S ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D SPHFLASMR4Y_01419 rpsE; 30S ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D SPHFLASMR4Y_00925 rpsF; 30S ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D SPHFLASMR4Y_01440 rpsG; 30S ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D SPHFLASMR4Y_01422 rpsH; 30S ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D SPHFLASMR4Y_02201 rpsI; 30S ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D SPHFLASMR4Y_01437 rpsJ; 30S ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D SPHFLASMR4Y_01408 rpsK; 30S ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D SPHFLASMR4Y_01441 rpsL; 30S ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D SPHFLASMR4Y_01409 rpsM; 30S ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D SPHFLASMR4Y_01423 rpsN; 30S ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SPHFLASMR4Y_00594 rpsO; 30S ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D SPHFLASMR4Y_00863 rpsP; 30S ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D SPHFLASMR4Y_01427 rpsQ; 30S ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D SPHFLASMR4Y_00926 rpsR; 30S ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D SPHFLASMR4Y_01432 rpsS; 30S ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D SPHFLASMR4Y_02755 rpsT; 30S ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D SPHFLASMR4Y_01972 rpsU; 30S ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D SPHFLASMR4Y_01999 rplA; 50S ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D SPHFLASMR4Y_01433 rplB; 50S ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D SPHFLASMR4Y_01436 rplC; 50S ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D SPHFLASMR4Y_01435 rplD; 50S ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D SPHFLASMR4Y_01424 rplE; 50S ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D SPHFLASMR4Y_01421 rplF; 50S ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D SPHFLASMR4Y_00927 rplI; 50S ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D SPHFLASMR4Y_02002 rplJ; 50S ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D SPHFLASMR4Y_01998 rplK; 50S ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D SPHFLASMR4Y_02003 rplL; 50S ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D SPHFLASMR4Y_02202 rplM; 50S ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D SPHFLASMR4Y_01426 rplN; 50S ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D SPHFLASMR4Y_01417 rplO; 50S ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D SPHFLASMR4Y_01429 rplP; 50S ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D SPHFLASMR4Y_01406 rplQ; 50S ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D SPHFLASMR4Y_01420 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D SPHFLASMR4Y_00859 rplS; 50S ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D SPHFLASMR4Y_02404 rplT; 50S ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D SPHFLASMR4Y_02040 rplU; 50S ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D SPHFLASMR4Y_01431 rplV; 50S ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D SPHFLASMR4Y_01434 rplW; 50S ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D SPHFLASMR4Y_01425 rplX; 50S ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D SPHFLASMR4Y_02041 rpmA; 50S ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D SPHFLASMR4Y_01963 rpmB; 50S ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D SPHFLASMR4Y_01428 rpmC; 50S ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D SPHFLASMR4Y_01418 rpmD; 50S ribosomal protein L30 K02907 RP-L30; large subunit ribosomal protein L30
D SPHFLASMR4Y_01288 rpmE; 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D SPHFLASMR4Y_02782 rpmF; 50S ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D SPHFLASMR4Y_02242 rpmG; 50S ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D SPHFLASMR4Y_02405 rpmI; 50S ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D SPHFLASMR4Y_00937 rplY; 50S ribosomal protein L25 K02897 RP-L25; large subunit ribosomal protein L25
D SPHFLASMR4Y_01474 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D SPHFLASMR4Y_01478 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D SPHFLASMR4Y_01475 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:sfla03009]
D SPHFLASMR4Y_00824 rnc; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D SPHFLASMR4Y_03294 ftsH3; ATP-dependent zinc metalloprotease FtsH 3 K13525 VCP; transitional endoplasmic reticulum ATPase
D SPHFLASMR4Y_00825 obgE; GTPase ObgE K03595 era; GTPase
D SPHFLASMR4Y_01861 obgE; GTPase ObgE K03979 obgE; GTPase [EC:3.6.5.-]
D SPHFLASMR4Y_03015 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D SPHFLASMR4Y_03305 dksA; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D SPHFLASMR4Y_00586 hypothetical protein K02600 nusA; transcription termination/antitermination protein NusA
D SPHFLASMR4Y_00033 transcription antitermination factor NusB K03625 nusB; transcription antitermination protein NusB
D SPHFLASMR4Y_01997 hypothetical protein K02601 nusG; transcription termination/antitermination protein NusG
D SPHFLASMR4Y_01343 rsmA; ribosomal RNA small subunit methyltransferase A K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D SPHFLASMR4Y_01544 rsmB; ribosomal RNA small subunit methyltransferase B K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D SPHFLASMR4Y_01243 rsmB; ribosomal RNA small subunit methyltransferase B K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D SPHFLASMR4Y_01211 rsmD; ribosomal RNA small subunit methyltransferase D K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D SPHFLASMR4Y_03265 rsmE; ribosomal RNA small subunit methyltransferase E K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D SPHFLASMR4Y_02306 rsmG; ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D SPHFLASMR4Y_00081 rsmH; ribosomal RNA small subunit methyltransferase H K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D SPHFLASMR4Y_00146 rsmI; ribosomal RNA small subunit methyltransferase I K07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]
D SPHFLASMR4Y_02768 tlyA; 16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA K06442 tlyA; 23S rRNA (cytidine1920-2'-O)/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]
D SPHFLASMR4Y_01622 rlmB; 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D SPHFLASMR4Y_00538 rlmE; ribosomal RNA large subunit methyltransferase E K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D SPHFLASMR4Y_02514 rlmH; ribosomal RNA large subunit methyltransferase H K00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]
D SPHFLASMR4Y_03053 rlmI; ribosomal RNA large subunit methyltransferase I K06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]
D SPHFLASMR4Y_00576 rlmN; dual-specificity RNA methyltransferase RlmN K06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]
D SPHFLASMR4Y_00837 rlmD; 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD K03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]
D SPHFLASMR4Y_01210 rluB; ribosomal large subunit pseudouridine synthase B K06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]
D SPHFLASMR4Y_01823 rluC; ribosomal large subunit pseudouridine synthase C K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D SPHFLASMR4Y_00890 rluD; ribosomal large subunit pseudouridine synthase D K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D SPHFLASMR4Y_00512 rluE; ribosomal large subunit pseudouridine synthase E K06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]
D SPHFLASMR4Y_00693 rimI; ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D SPHFLASMR4Y_01411 rimK; ribosomal protein S6--L-glutamate ligase K05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]
D SPHFLASMR4Y_00862 rimM; ribosome maturation factor RimM K02860 rimM; 16S rRNA processing protein RimM
D SPHFLASMR4Y_03025 rimO; ribosomal protein S12 methylthiotransferase RimO K14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]
D SPHFLASMR4Y_00605 prmA; ribosomal protein L11 methyltransferase K02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]
D SPHFLASMR4Y_00511 roxA; 50S ribosomal protein L16 3-hydroxylase K18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]
D SPHFLASMR4Y_00541 rne; ribonuclease E K08300 rne; ribonuclease E [EC:3.1.26.12]
D SPHFLASMR4Y_00902 yrrK; putative pre-16S rRNA nuclease K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D SPHFLASMR4Y_03262 deaD; ATP-dependent RNA helicase DeaD K05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]
D SPHFLASMR4Y_01908 der; GTPase Der K03977 engA; GTPase
D SPHFLASMR4Y_00773 obgE; GTPase ObgE K03665 hflX; GTPase
D SPHFLASMR4Y_02022 ywlC; threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D SPHFLASMR4Y_01970 rsh; GTP pyrophosphokinase rsh K01139 spoT; GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]
D SPHFLASMR4Y_00589 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D SPHFLASMR4Y_00585 rimP; ribosome maturation factor RimP K09748 rimP; ribosome maturation factor RimP
D SPHFLASMR4Y_02513 rsfS; ribosomal silencing factor RsfS K09710 ybeB; ribosome-associated protein
D SPHFLASMR4Y_00687 ybeY; endoribonuclease YbeY K07042 ybeY; probable rRNA maturation factor
D SPHFLASMR4Y_02291 yvyD; ribosome hibernation promotion factor K05808 hpf; ribosome hibernation promoting factor
D SPHFLASMR4Y_00939 obgE; GTPase ObgE K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:sfla03016]
D SPHFLASMR4Y_02173 rnz; ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D SPHFLASMR4Y_03244 ribonuclease K01166 RNASET2; ribonuclease T2 [EC:4.6.1.19]
D SPHFLASMR4Y_01096 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_02411 gltX1; glutamate--tRNA ligase 1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_00810 proS; proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SPHFLASMR4Y_01537 ileS; isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SPHFLASMR4Y_02276 ileS; isoleucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SPHFLASMR4Y_00778 ileS; isoleucine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SPHFLASMR4Y_00063 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SPHFLASMR4Y_01320 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SPHFLASMR4Y_01307 alaS; alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SPHFLASMR4Y_03198 thrS; threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SPHFLASMR4Y_03018 serS; serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SPHFLASMR4Y_00013 cysS; cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SPHFLASMR4Y_03156 ileS; isoleucine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SPHFLASMR4Y_02479 hisS; histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SPHFLASMR4Y_02403 pheS; phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SPHFLASMR4Y_02402 pheT; phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SPHFLASMR4Y_01046 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SPHFLASMR4Y_02495 trpS; tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D SPHFLASMR4Y_03092 purine nucleoside phosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D SPHFLASMR4Y_02044 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D SPHFLASMR4Y_00978 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D SPHFLASMR4Y_00593 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D SPHFLASMR4Y_00959 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_00960 iscS; IscS-like cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_02022 ywlC; threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D SPHFLASMR4Y_00910 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D SPHFLASMR4Y_02304 mnmE; tRNA modification GTPase MnmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D SPHFLASMR4Y_02305 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D SPHFLASMR4Y_00222 cysQ; 3'-phosphoadenosine 5'-phosphate phosphatase K01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]
D SPHFLASMR4Y_02505 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D SPHFLASMR4Y_00885 RNaseP_bact_a K01978 rnpB; M1 RNA
D SPHFLASMR4Y_00156 rph; ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D SPHFLASMR4Y_01325 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D SPHFLASMR4Y_02235 rnd; ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D SPHFLASMR4Y_02633 lysK; lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D SPHFLASMR4Y_00932 glyQ; glycine--tRNA ligase alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D SPHFLASMR4Y_00931 glyS; glycine--tRNA ligase beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D SPHFLASMR4Y_01854 gltX; glutamate--tRNA ligase K01894 gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]
D SPHFLASMR4Y_01964 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D SPHFLASMR4Y_00767 dus; putative tRNA-dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D SPHFLASMR4Y_00689 miaB; tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D SPHFLASMR4Y_00867 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB K18707 mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB [EC:2.8.4.5]
D SPHFLASMR4Y_01262 trmJ; tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ K02533 lasT; tRNA/rRNA methyltransferase [EC:2.1.1.-]
D SPHFLASMR4Y_01016 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D SPHFLASMR4Y_00860 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D SPHFLASMR4Y_03219 trmH; tRNA (guanosine(18)-2'-O)-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D SPHFLASMR4Y_00741 trmL; tRNA (cytidine(34)-2'-O)-methyltransferase K03216 trmL; tRNA (cytidine/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]
D SPHFLASMR4Y_00971 aviRb; 23S rRNA (uridine(2479)-2'-O)-methyltransferase K03437 spoU; RNA methyltransferase, TrmH family
D SPHFLASMR4Y_02078 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D SPHFLASMR4Y_02467 iscA; iron-binding protein IscA K13628 iscA; iron-sulfur cluster assembly protein
D SPHFLASMR4Y_02483 putative global regulator K06980 ygfZ; tRNA-modifying protein YgfZ
D SPHFLASMR4Y_01890 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D SPHFLASMR4Y_00734 queC; 7-cyano-7-deazaguanine synthase K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D SPHFLASMR4Y_00735 queE; 7-carboxy-7-deazaguanine synthase K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D SPHFLASMR4Y_01837 queF; NADPH-dependent 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D SPHFLASMR4Y_01777 queG; epoxyqueuosine reductase K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D SPHFLASMR4Y_01882 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D SPHFLASMR4Y_03327 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D SPHFLASMR4Y_00694 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D SPHFLASMR4Y_01771 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D SPHFLASMR4Y_01066 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D SPHFLASMR4Y_00809 rnr; ribonuclease R K12573 rnr; ribonuclease R [EC:3.1.13.1]
D SPHFLASMR4Y_00595 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:sfla03012]
D SPHFLASMR4Y_00588 tuf; elongation factor Tu K02519 infB; translation initiation factor IF-2
D SPHFLASMR4Y_03197 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D SPHFLASMR4Y_00606 glnQ; glutamine ABC transporter ATP-binding protein K06158 ABCF3; ATP-binding cassette, subfamily F, member 3
D SPHFLASMR4Y_01298 tsf; elongation factor Ts K02357 tsf; elongation factor Ts
D SPHFLASMR4Y_01438 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D SPHFLASMR4Y_01439 fusA; elongation factor G K02355 fusA; elongation factor G
D SPHFLASMR4Y_02480 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D SPHFLASMR4Y_01296 frr; ribosome-recycling factor K02838 frr; ribosome recycling factor
D SPHFLASMR4Y_02481 prmC; release factor glutamine methyltransferase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D SPHFLASMR4Y_00938 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D SPHFLASMR4Y_00042 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D SPHFLASMR4Y_01127 efp; elongation factor P K02356 efp; elongation factor P
D SPHFLASMR4Y_00558 prfB; peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
D SPHFLASMR4Y_02401 prfC; peptide chain release factor 3 K02837 prfC; peptide chain release factor 3
D SPHFLASMR4Y_00651 arfB; peptidyl-tRNA hydrolase ArfB K15034 yaeJ; ribosome-associated protein
C 03110 Chaperones and folding catalysts [BR:sfla03110]
D SPHFLASMR4Y_00448 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA
D SPHFLASMR4Y_03372 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D SPHFLASMR4Y_00893 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D SPHFLASMR4Y_00699 hslU; ATP-dependent protease ATPase subunit HslU K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
D SPHFLASMR4Y_00173 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D SPHFLASMR4Y_02177 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SPHFLASMR4Y_00174 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D SPHFLASMR4Y_00732 hslO; molecular chaperone Hsp33 K04083 hslO; molecular chaperone Hsp33
D SPHFLASMR4Y_00158 heat shock protein GrpE K03687 GRPE; molecular chaperone GrpE
D SPHFLASMR4Y_01075 ibpA; small heat shock protein IbpA K04080 ibpA; molecular chaperone IbpA
D SPHFLASMR4Y_02033 hslR; heat shock protein 15 K04762 hslR; ribosome-associated heat shock protein Hsp15
D SPHFLASMR4Y_02178 groS; molecular chaperone GroES K04078 groES; chaperonin GroES
D SPHFLASMR4Y_01833 degP; periplasmic serine endoprotease DegP K04771 degP; serine protease Do [EC:3.4.21.107]
D SPHFLASMR4Y_03326 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D SPHFLASMR4Y_01188 atpB; ATP synthase subunit a K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D SPHFLASMR4Y_01556 putative fimbrial chaperone protein K07346 fimC; fimbrial chaperone protein
D SPHFLASMR4Y_02497 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D SPHFLASMR4Y_00172 copper chaperone PCu(A)C K09796 pccA; periplasmic copper chaperone A
D SPHFLASMR4Y_01167 epr; minor extracellular protease Epr K13277 epr; minor extracellular protease Epr [EC:3.4.21.-]
D SPHFLASMR4Y_01080 ppiD; peptidyl-prolyl cis-trans isomerase D K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]
D SPHFLASMR4Y_01341 surA; chaperone SurA K03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]
D SPHFLASMR4Y_01061 trxA; thioredoxin-1 K03671 TXN; thioredoxin
D SPHFLASMR4Y_01561 trxA; thioredoxin K05838 ybbN; putative thioredoxin
D SPHFLASMR4Y_00204 grxC; glutaredoxin-3 K03676 grxC; glutaredoxin 3
D SPHFLASMR4Y_03233 grxD; glutaredoxin-4 K07390 grxD; monothiol glutaredoxin
D SPHFLASMR4Y_00395 dsbC; thiol:disulfide interchange protein DsbC K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
D SPHFLASMR4Y_01269 dsbE; thiol:disulfide interchange protein DsbE K02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE
C 04131 Membrane trafficking [BR:sfla04131]
D SPHFLASMR4Y_01337 ndk; nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D SPHFLASMR4Y_03294 ftsH3; ATP-dependent zinc metalloprotease FtsH 3 K13525 VCP; transitional endoplasmic reticulum ATPase
D SPHFLASMR4Y_02240 membrane protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_01132 gapA; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D SPHFLASMR4Y_01530 gpmA; phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SPHFLASMR4Y_02219 ttuE; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
C 04121 Ubiquitin system
C 03051 Proteasome
C 03032 DNA replication proteins [BR:sfla03032]
D SPHFLASMR4Y_00059 rnhA; ribonuclease HI K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D SPHFLASMR4Y_01499 hpaIIM; modification methylase HpaII K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SPHFLASMR4Y_00953 hupB; DNA-binding protein HRm K03530 hupB; DNA-binding protein HU-beta
D SPHFLASMR4Y_02628 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
D SPHFLASMR4Y_03252 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
D SPHFLASMR4Y_02757 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D SPHFLASMR4Y_00658 dnaC; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D SPHFLASMR4Y_01037 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D SPHFLASMR4Y_00366 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_03338 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_01071 dnaE2; DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SPHFLASMR4Y_00573 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SPHFLASMR4Y_01338 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D SPHFLASMR4Y_02278 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SPHFLASMR4Y_00779 dnaX; DNA polymerase III subunit tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SPHFLASMR4Y_02292 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SPHFLASMR4Y_00956 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SPHFLASMR4Y_00638 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D SPHFLASMR4Y_02166 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SPHFLASMR4Y_00600 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D SPHFLASMR4Y_01013 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D SPHFLASMR4Y_01927 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D SPHFLASMR4Y_02837 parC; DNA topoisomerase 4 subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D SPHFLASMR4Y_01175 parE; DNA topoisomerase 4 subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D SPHFLASMR4Y_00826 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D SPHFLASMR4Y_03182 eukaryotic DNA topoisomerase I, catalytic core K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:sfla03036]
D SPHFLASMR4Y_01499 hpaIIM; modification methylase HpaII K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SPHFLASMR4Y_00824 rnc; ribonuclease 3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_00357 P-loop containing NTP hydrolase pore-1 K26273 SBNO; protein strawberry notch
D SPHFLASMR4Y_00953 hupB; DNA-binding protein HRm K03530 hupB; DNA-binding protein HU-beta
D SPHFLASMR4Y_02628 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
D SPHFLASMR4Y_03252 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
D SPHFLASMR4Y_02757 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D SPHFLASMR4Y_01172 hspQ; heat shock protein HspQ K11940 hspQ; heat shock protein HspQ
D SPHFLASMR4Y_02239 dps1; DNA protection during starvation protein 1 K04047 dps; starvation-inducible DNA-binding protein
D SPHFLASMR4Y_02695 dps; DNA protection during starvation protein K04047 dps; starvation-inducible DNA-binding protein
D SPHFLASMR4Y_00772 hfq; RNA-binding protein Hfq K03666 hfq; host factor-I protein
D SPHFLASMR4Y_03280 smc; chromosome partition protein Smc K03529 smc; chromosome segregation protein
D SPHFLASMR4Y_00066 scpA; segregation and condensation protein A K05896 scpA; segregation and condensation protein A
D SPHFLASMR4Y_00067 segregation and condensation protein B K06024 scpB; segregation and condensation protein B
D SPHFLASMR4Y_00095 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D SPHFLASMR4Y_02388 glnQ; glutamine ABC transporter ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D SPHFLASMR4Y_00083 ftsI; peptidoglycan synthase FtsI K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D SPHFLASMR4Y_03344 ftsK; DNA translocase FtsK K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D SPHFLASMR4Y_00094 cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ
D SPHFLASMR4Y_00088 ftsW; putative lipid II flippase FtsW K03588 ftsW; cell division protein FtsW
D SPHFLASMR4Y_02389 cell division ABC transporter subunit FtsX K09811 ftsX; cell division transport system permease protein
D SPHFLASMR4Y_00096 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D SPHFLASMR4Y_01135 cell division protein ZapA K09888 zapA; cell division protein ZapA
D SPHFLASMR4Y_02196 zapE; cell division protein ZapE K06916 zapE; cell division protein ZapE
D SPHFLASMR4Y_00542 amiC; N-acetylmuramoyl-L-alanine amidase AmiC K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D SPHFLASMR4Y_00788 acrA; multidrug efflux pump subunit AcrA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_02021 mdtA; multidrug resistance protein MdtA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_00943 dnaK; molecular chaperone DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D SPHFLASMR4Y_02652 dnaK; molecular chaperone DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D SPHFLASMR4Y_00944 mreC; cell shape-determining protein MreC K03570 mreC; rod shape-determining protein MreC
D SPHFLASMR4Y_00945 rod shape-determining protein MreD K03571 mreD; rod shape-determining protein MreD
D SPHFLASMR4Y_00947 mrdB; rod shape-determining protein RodA K05837 rodA; rod shape determining protein RodA
D SPHFLASMR4Y_00907 AAA domain protein K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_02307 parA; chromosome partitioning protein ParA K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_02251 soj; sporulation initiation inhibitor protein Soj K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_01977 soj; sporulation initiation inhibitor protein Soj K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_02308 parB; chromosome-partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D SPHFLASMR4Y_00358 spo0C; chromosome-partitioning protein Spo0J K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D SPHFLASMR4Y_02837 parC; DNA topoisomerase 4 subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D SPHFLASMR4Y_01175 parE; DNA topoisomerase 4 subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D SPHFLASMR4Y_02305 mnmG; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D SPHFLASMR4Y_02306 rsmG; ribosomal RNA small subunit methyltransferase G K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D SPHFLASMR4Y_01016 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO K04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]
D SPHFLASMR4Y_00151 xerC; tyrosine recombinase XerC K03733 xerC; integrase/recombinase XerC
D SPHFLASMR4Y_00196 xerD; tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD
D SPHFLASMR4Y_01829 apbC; iron-sulfur cluster carrier protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D SPHFLASMR4Y_02503 engB; putative GTP-binding protein EngB K03978 engB; GTP-binding protein
C 03400 DNA repair and recombination proteins [BR:sfla03400]
D SPHFLASMR4Y_01234 phrA; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SPHFLASMR4Y_00514 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_03284 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
D SPHFLASMR4Y_01916 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SPHFLASMR4Y_02727 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SPHFLASMR4Y_00201 mutT; 8-oxo-dGTP diphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPHFLASMR4Y_02749 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SPHFLASMR4Y_00139 ada; bifunctional transcriptional activator/DNA repair enzyme Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SPHFLASMR4Y_01838 phrB; (6-4) photolyase K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D SPHFLASMR4Y_00845 Uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_01252 Uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_03357 DNA polymerase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SPHFLASMR4Y_01625 alkA; DNA-3-methyladenine glycosylase 2 K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D SPHFLASMR4Y_02854 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
D SPHFLASMR4Y_02754 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D SPHFLASMR4Y_01876 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SPHFLASMR4Y_03342 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SPHFLASMR4Y_02881 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D SPHFLASMR4Y_00600 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D SPHFLASMR4Y_02166 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
D SPHFLASMR4Y_03077 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
D SPHFLASMR4Y_03310 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
D SPHFLASMR4Y_01184 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
D SPHFLASMR4Y_01213 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D SPHFLASMR4Y_02009 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D SPHFLASMR4Y_02010 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D SPHFLASMR4Y_01407 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D SPHFLASMR4Y_03325 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D SPHFLASMR4Y_01050 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D SPHFLASMR4Y_01577 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D SPHFLASMR4Y_00942 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D SPHFLASMR4Y_03364 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D SPHFLASMR4Y_01894 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D SPHFLASMR4Y_01071 dnaE2; DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D SPHFLASMR4Y_00573 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D SPHFLASMR4Y_01338 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
D SPHFLASMR4Y_02278 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D SPHFLASMR4Y_00779 dnaX; DNA polymerase III subunit tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D SPHFLASMR4Y_02292 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D SPHFLASMR4Y_00956 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D SPHFLASMR4Y_00366 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_03338 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_01310 recombinase A K03553 recA; recombination protein RecA
D SPHFLASMR4Y_02211 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D SPHFLASMR4Y_02210 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D SPHFLASMR4Y_02212 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D SPHFLASMR4Y_00141 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D SPHFLASMR4Y_00187 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
D SPHFLASMR4Y_01461 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D SPHFLASMR4Y_01048 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D SPHFLASMR4Y_01181 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D SPHFLASMR4Y_00976 recR; recombination protein RecR K06187 recR; recombination protein RecR
D SPHFLASMR4Y_00597 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D SPHFLASMR4Y_01062 addA; ATP-dependent helicase/nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D SPHFLASMR4Y_01063 PD-(D/E)XK nuclease superfamily protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D SPHFLASMR4Y_01834 ATPase family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
D SPHFLASMR4Y_01013 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D SPHFLASMR4Y_01927 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D SPHFLASMR4Y_00826 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D SPHFLASMR4Y_03182 eukaryotic DNA topoisomerase I, catalytic core K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D SPHFLASMR4Y_00953 hupB; DNA-binding protein HRm K03530 hupB; DNA-binding protein HU-beta
D SPHFLASMR4Y_02628 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
D SPHFLASMR4Y_03252 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
D SPHFLASMR4Y_03391 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
D SPHFLASMR4Y_02804 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SPHFLASMR4Y_01094 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SPHFLASMR4Y_02693 recA-like protein K14160 imuA; protein ImuA
D SPHFLASMR4Y_02692 DNA polymerase IV K14161 imuB; protein ImuB
D SPHFLASMR4Y_02691 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D SPHFLASMR4Y_01980 recombination regulator RecX K03565 recX; regulatory protein
D SPHFLASMR4Y_02631 ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D SPHFLASMR4Y_02261 cshB; DEAD-box ATP-dependent RNA helicase CshB K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D SPHFLASMR4Y_03398 nrdZ; vitamin B12-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPHFLASMR4Y_03400 nrdB; ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:sfla03029]
D SPHFLASMR4Y_00743 petB; cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D SPHFLASMR4Y_00588 tuf; elongation factor Tu K02519 infB; translation initiation factor IF-2
D SPHFLASMR4Y_03197 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D SPHFLASMR4Y_01298 tsf; elongation factor Ts K02357 tsf; elongation factor Ts
D SPHFLASMR4Y_01438 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D SPHFLASMR4Y_01439 fusA; elongation factor G K02355 fusA; elongation factor G
D SPHFLASMR4Y_01580 ubiquinol-cytochrome C chaperone K17662 CBP3; cytochrome b pre-mRNA-processing protein 3
D SPHFLASMR4Y_02034 helicase K17675 SUPV3L1; ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:5.6.2.6]
D SPHFLASMR4Y_00825 obgE; GTPase ObgE K03595 era; GTPase
D SPHFLASMR4Y_01046 tyrS; tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SPHFLASMR4Y_02276 ileS; isoleucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SPHFLASMR4Y_01320 aspS; aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D SPHFLASMR4Y_00063 argS; arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SPHFLASMR4Y_00899 gatA; aspartyl/glutamyl-tRNA amidotransferase subunit A K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SPHFLASMR4Y_00898 gatB; aspartyl/glutamyl-tRNA amidotransferase subunit B K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D SPHFLASMR4Y_00900 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D SPHFLASMR4Y_00366 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_03338 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPHFLASMR4Y_01291 bamA; outer membrane protein assembly factor BamA K07277 SAM50; outer membrane protein insertion porin family
D SPHFLASMR4Y_00173 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D SPHFLASMR4Y_00158 heat shock protein GrpE K03687 GRPE; molecular chaperone GrpE
D SPHFLASMR4Y_02177 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SPHFLASMR4Y_02178 groS; molecular chaperone GroES K04078 groES; chaperonin GroES
D SPHFLASMR4Y_00174 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D SPHFLASMR4Y_00959 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_00960 iscS; IscS-like cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_00958 camB; putidaredoxin K22071 FDX2; ferredoxin-2, mitochondrial
D SPHFLASMR4Y_03233 grxD; glutaredoxin-4 K07390 grxD; monothiol glutaredoxin
D SPHFLASMR4Y_00202 methyltransferase domain protein K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D SPHFLASMR4Y_01585 putative S-adenosyl-L-methionine-dependent methyltransferase K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D SPHFLASMR4Y_01829 apbC; iron-sulfur cluster carrier protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D SPHFLASMR4Y_03046 ctaB; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D SPHFLASMR4Y_03048 ctaG; cytochrome c oxidase assembly protein CtaG K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D SPHFLASMR4Y_02203 ctaA; heme A synthase K02259 COX15; heme a synthase [EC:1.17.99.9]
D SPHFLASMR4Y_02504 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SPHFLASMR4Y_03051 SURF1 family protein K14998 SURF1; surfeit locus 1 family protein
D SPHFLASMR4Y_02284 electron transporter K07152 SCO1; protein SCO1
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:sfla02000]
D SPHFLASMR4Y_02438 glnQ; glutamine ABC transporter ATP-binding protein K24846 pglK; ATP-binding cassette, subfamily B, bacterial PglK [EC:7.5.2.-]
D SPHFLASMR4Y_03392 glnQ; glutamine ABC transporter ATP-binding protein K24821 atm1; ATP-binding cassette, subfamily B, heavy metal transporter
D SPHFLASMR4Y_02892 glnQ; glutamine ABC transporter ATP-binding protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D SPHFLASMR4Y_01664 glnQ; glutamine ABC transporter ATP-binding protein K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB
D SPHFLASMR4Y_01365 glnQ; glutamine ABC transporter ATP-binding protein K15738 uup; ABC transport system ATP-binding/permease protein
D SPHFLASMR4Y_02540 nrtA; nitrate transport protein NrtA K15576 nrtA; nitrate/nitrite transport system substrate-binding protein
D SPHFLASMR4Y_02541 cmpB; bicarbonate transport system permease protein CmpB K15577 nrtB; nitrate/nitrite transport system permease protein
D SPHFLASMR4Y_02542 glnQ; glutamine ABC transporter ATP-binding protein K15578 nrtC; nitrate/nitrite transport system ATP-binding protein [EC:7.3.2.4]
D SPHFLASMR4Y_01628 opuBB; choline transport system permease protein OpuBB K05845 opuC; osmoprotectant transport system substrate-binding protein
D SPHFLASMR4Y_01629 glnQ; arginine ABC transporter ATP-binding protein K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
D SPHFLASMR4Y_01587 MlaD protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D SPHFLASMR4Y_01589 mlaE; putative phospholipid ABC transporter permease protein MlaE K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D SPHFLASMR4Y_01588 glnQ; glutamine ABC transporter ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D SPHFLASMR4Y_01586 ABC-type transport auxiliary lipoprotein component K18480 linN; cholesterol transport system auxiliary component
D SPHFLASMR4Y_00715 pstS; phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D SPHFLASMR4Y_00545 pstS; phosphate-binding protein PstS K02040 pstS; phosphate transport system substrate-binding protein
D SPHFLASMR4Y_00714 pstC1; phosphate transport system permease protein PstC 1 K02037 pstC; phosphate transport system permease protein
D SPHFLASMR4Y_00713 pstA; phosphate transport system permease protein PstA K02038 pstA; phosphate transport system permease protein
D SPHFLASMR4Y_00712 glnQ; glutamine ABC transporter ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SPHFLASMR4Y_03249 oppA; periplasmic oligopeptide-binding protein K15580 oppA; oligopeptide transport system substrate-binding protein
D SPHFLASMR4Y_01845 oppB; oligopeptide transport system permease protein OppB K15581 oppB; oligopeptide transport system permease protein
D SPHFLASMR4Y_01844 oppC; oligopeptide transport system permease protein OppC K15582 oppC; oligopeptide transport system permease protein
D SPHFLASMR4Y_01843 glnQ; glutamine ABC transporter ATP-binding protein K10823 oppF; oligopeptide transport system ATP-binding protein
D SPHFLASMR4Y_03248 gsiB; glutathione-binding protein GsiB K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SPHFLASMR4Y_01872 putative permease YjgP/YjgQ family protein K07091 lptF; lipopolysaccharide export system permease protein
D SPHFLASMR4Y_01873 lptG; lipopolysaccharide export system permease protein LptG K11720 lptG; lipopolysaccharide export system permease protein
D SPHFLASMR4Y_02232 glnQ; glutamine ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D SPHFLASMR4Y_00296 glnQ; glutamine ABC transporter ATP-binding protein K06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]
D SPHFLASMR4Y_01074 lolE; lipoprotein-releasing system transmembrane protein LolE K09808 lolC_E; lipoprotein-releasing system permease protein
D SPHFLASMR4Y_01073 glnQ; glutamine ABC transporter ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D SPHFLASMR4Y_01273 ccmC; heme exporter protein C K02195 ccmC; heme exporter protein C
D SPHFLASMR4Y_01633 ccmB; heme exporter protein B K02194 ccmB; heme exporter protein B
D SPHFLASMR4Y_01632 ccmA; cytochrome c biogenesis ATP-binding export protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D SPHFLASMR4Y_02389 cell division ABC transporter subunit FtsX K09811 ftsX; cell division transport system permease protein
D SPHFLASMR4Y_02388 glnQ; glutamine ABC transporter ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
D SPHFLASMR4Y_01779 ABC-2 family transporter protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SPHFLASMR4Y_01173 yadH; inner membrane transport permease YadH K01992 ABC-2.P; ABC-2 type transport system permease protein
D SPHFLASMR4Y_01778 glnQ; glutamine ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SPHFLASMR4Y_03376 glnQ; glutamine ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SPHFLASMR4Y_00526 FtsX-like permease family protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SPHFLASMR4Y_00527 glnQ; glutamine ABC transporter ATP-binding protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SPHFLASMR4Y_02463 sufC; ABC transporter ATP-binding protein K09013 sufC; Fe-S cluster assembly ATP-binding protein
D SPHFLASMR4Y_00525 sodium:proton symporter K14347 SLC10A7; solute carrier family 10 (sodium/bile acid cotransporter), member 7
D SPHFLASMR4Y_01599 sdcS; sodium-dependent dicarboxylate transporter SdcS K14445 SLC13A2_3_5; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5
D SPHFLASMR4Y_00168 norM; multidrug resistance protein NorM K26939 norM; MATE family, multidrug efflux pump
D SPHFLASMR4Y_03009 mepA; multidrug export protein MepA K26937 dinF; MATE family, multidrug efflux pump
D SPHFLASMR4Y_02718 emrB; multidrug resistance protein B K23677 SPNS; MFS transporter, Spinster family, sphingosine-1-phosphate transporter
D SPHFLASMR4Y_00551 muropeptide transporter K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D SPHFLASMR4Y_01208 muropeptide transporter K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D SPHFLASMR4Y_02739 folate-biopterin transporter K08218 ampG; MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG
D SPHFLASMR4Y_00455 emrB; DSBA oxidoreductase K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
D SPHFLASMR4Y_02802 emrB; MFS transporter K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein
D SPHFLASMR4Y_00857 emrB; multidrug resistance protein B K03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein
D SPHFLASMR4Y_03330 ptsI; phosphoenolpyruvate-protein phosphotransferase K08484 ptsP; phosphotransferase system, enzyme I, PtsP [EC:2.7.3.9]
D SPHFLASMR4Y_00970 ptsO; phosphocarrier protein NPr K02784 ptsH; phosphocarrier protein HPr
D SPHFLASMR4Y_00969 manX; PTS system mannose-specific EIIAB component K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SPHFLASMR4Y_02290 ptsN; nitrogen regulatory protein K02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]
D SPHFLASMR4Y_03021 kch; voltage-gated potassium channel Kch K10716 kch; voltage-gated potassium channel
D SPHFLASMR4Y_00670 amtB; ammmonia channel K03320 amt; ammonium transporter, Amt family
D SPHFLASMR4Y_03386 amt; ammmonia channel K03320 amt; ammonium transporter, Amt family
D SPHFLASMR4Y_00075 yibF; putative GST-like protein YibF K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_01309 gstB; glutathione S-transferase GST-6.0 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02092 yfcG; disulfide-bond oxidoreductase YfcG K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_00440 gstB; glutathione S-transferase GST-6.0 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02502 yfcF; glutathione S-transferase YfcF K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02528 gstB; glutathione S-transferase GstB K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_03221 sspA; stringent starvation protein A K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_03223 glutathionine S-transferase K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02993 gst; glutathione S-transferase GST-4.5 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02256 MAPEG family protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_02265 glutaredoxin 2 K00799 GST; glutathione S-transferase [EC:2.5.1.18]
D SPHFLASMR4Y_03352 arginine biosynthesis protein ArgJ K07114 yfbK; Ca-activated chloride channel homolog
D SPHFLASMR4Y_01352 mscL; large-conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel
D SPHFLASMR4Y_02858 mscS; small-conductance mechanosensitive channel K03442 mscS; small conductance mechanosensitive channel
D SPHFLASMR4Y_02863 mscS; small-conductance mechanosensitive channel K03442 mscS; small conductance mechanosensitive channel
D SPHFLASMR4Y_03358 ybdG; miniconductance mechanosensitive channel YbdG K16053 ybdG; miniconductance mechanosensitive channel
D SPHFLASMR4Y_03289 magnesium transporter MgtE K06213 mgtE; magnesium transporter
D SPHFLASMR4Y_01652 exbB; biopolymer transport protein ExbB K03561 exbB; biopolymer transport protein ExbB
D SPHFLASMR4Y_02889 exbB; biopolymer transport protein ExbB K03561 exbB; biopolymer transport protein ExbB
D SPHFLASMR4Y_01651 exbD; biopolymer transport protein ExbD K03559 exbD; biopolymer transport protein ExbD
D SPHFLASMR4Y_02890 exbD; biopolymer transport protein ExbD K03559 exbD; biopolymer transport protein ExbD
D SPHFLASMR4Y_02891 exbD; biopolymer transport protein ExbD K03559 exbD; biopolymer transport protein ExbD
D SPHFLASMR4Y_03137 exbD; biopolymer transport protein ExbD K03559 exbD; biopolymer transport protein ExbD
D SPHFLASMR4Y_03303 exbB; biopolymer transport protein ExbB K03562 tolQ; biopolymer transport protein TolQ
D SPHFLASMR4Y_03302 exbD; biopolymer transport protein ExbD K03560 tolR; biopolymer transport protein TolR
D SPHFLASMR4Y_01824 crcB; putative fluoride ion transporter CrcB K06199 crcB; fluoride exporter
D SPHFLASMR4Y_02920 MerT mercuric transport protein K08363 merT; mercuric ion transport protein
D SPHFLASMR4Y_02919 merP; mercuric transport protein periplasmic component K08364 merP; periplasmic mercuric ion binding protein
D SPHFLASMR4Y_03348 corC; magnesium and cobalt efflux protein CorC K03699 tlyC; magnesium and cobalt exporter, CNNM family
D SPHFLASMR4Y_00578 outer membrane protein beta-barrel domain protein K16079 omp31; outer membrane immunogenic protein
D SPHFLASMR4Y_01806 outer membrane protein beta-barrel domain protein K16079 omp31; outer membrane immunogenic protein
D SPHFLASMR4Y_02090 outer membrane protein A K16079 omp31; outer membrane immunogenic protein
D SPHFLASMR4Y_02745 outer membrane protein A K16079 omp31; outer membrane immunogenic protein
D SPHFLASMR4Y_00547 oprP; porin P K07221 oprO_P; phosphate-selective porin OprO and OprP
D SPHFLASMR4Y_03351 yiaD; putative lipoprotein YiaD K03286 TC.OOP; OmpA-OmpF porin, OOP family
D SPHFLASMR4Y_01512 yiaD; putative lipoprotein YiaD K03286 TC.OOP; OmpA-OmpF porin, OOP family
D SPHFLASMR4Y_02830 outer membrane protein K03286 TC.OOP; OmpA-OmpF porin, OOP family
D SPHFLASMR4Y_03360 ompP1; outer membrane protein P1 K06076 fadL; long-chain fatty acid transport protein
D SPHFLASMR4Y_01557 caf1A; F1 capsule-anchoring protein K07347 fimD; outer membrane usher protein
D SPHFLASMR4Y_01649 bfrD; putative TonB-dependent receptor BfrD K16090 fiu; catecholate siderophore receptor
D SPHFLASMR4Y_01975 bfrD; putative TonB-dependent receptor BfrD K16090 fiu; catecholate siderophore receptor
D SPHFLASMR4Y_00802 btuB; vitamin B12 transporter BtuB K16092 btuB; vitamin B12 transporter
D SPHFLASMR4Y_03393 outer membrane protein beta-barrel family protein K16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins
D SPHFLASMR4Y_02709 hemR; hemin receptor K16087 TC.FEV.OM3; hemoglobin/transferrin/lactoferrin receptor protein
D SPHFLASMR4Y_00072 putative TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00180 fpvA; ferripyoverdine receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02126 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02152 bfrD; putative TonB-dependent receptor BfrD K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01171 fhuA; ferrichrome-iron receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01885 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00265 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00347 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_03000 btuB; vitamin B12 transporter BtuB K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02805 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02325 catecholate siderophore receptor CirA K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02565 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02574 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02586 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02351 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02373 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02917 iutA; ferric aerobactin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02720 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01930 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01931 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00041 TonB-dependent receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01446 cirA; colicin I receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01525 fhuE; FhuE receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01529 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00975 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00676 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00677 cirA; colicin I receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_00797 cirA; colicin I receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_01380 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02724 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_03123 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02549 fyuA; pesticin receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_03368 cirA; colicin I receptor K02014 TC.FEV.OM; iron complex outermembrane recepter protein
D SPHFLASMR4Y_02935 czcC; cobalt-zinc-cadmium resistance protein CzcC K15725 czcC; outer membrane protein, heavy metal efflux system
D SPHFLASMR4Y_02924 outer membrane efflux protein K15725 czcC; outer membrane protein, heavy metal efflux system
D SPHFLASMR4Y_03160 bepC; outer membrane efflux protein BepC K12340 tolC; outer membrane protein
D SPHFLASMR4Y_01665 bepC; outer membrane efflux protein BepC K12543 lapE; outer membrane protein, adhesin transport system
D SPHFLASMR4Y_00790 ttgI; toluene efflux pump outer membrane protein TtgI K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_01635 oprM; outer membrane protein OprM K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_00987 polysaccharide biosynthesis/export protein K01991 wza; polysaccharide biosynthesis/export protein
D SPHFLASMR4Y_02419 polysaccharide biosynthesis/export protein K01991 wza; polysaccharide biosynthesis/export protein
D SPHFLASMR4Y_01291 bamA; outer membrane protein assembly factor BamA K07277 SAM50; outer membrane protein insertion porin family
D SPHFLASMR4Y_01909 bamB; outer membrane protein assembly factor BamB K17713 bamB; outer membrane protein assembly factor BamB
D SPHFLASMR4Y_00596 bamD; outer membrane protein assembly factor BamD K05807 bamD; outer membrane protein assembly factor BamD
D SPHFLASMR4Y_01518 tama; translocation and assembly module TamA K07278 tamA; translocation and assembly module TamA
D SPHFLASMR4Y_01517 tamB; translocation and assembly module TamB K09800 tamB; translocation and assembly module TamB
D SPHFLASMR4Y_00303 hypothetical protein K21449 ata; trimeric autotransporter adhesin
D SPHFLASMR4Y_02233 lptA; lipopolysaccharide export system protein LptA K09774 lptA; lipopolysaccharide export system protein LptA
D SPHFLASMR4Y_02234 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC K11719 lptC; lipopolysaccharide export system protein LptC
D SPHFLASMR4Y_01340 lptD; LPS-assembly protein LptD K04744 lptD; LPS-assembly protein
D SPHFLASMR4Y_02277 lipopolysaccharide-assembly K03643 lptE; LPS-assembly lipoprotein
D SPHFLASMR4Y_00686 tlyC; hemolysin C K06189 corC; hemolysin (HlyC) family protein
D SPHFLASMR4Y_01458 fieF; cation-efflux pump FieF K16264 czcD; cobalt-zinc-cadmium efflux system protein
D SPHFLASMR4Y_02928 czcD; cadmium, cobalt and zinc/H(+)-K(+) antiporter K16264 czcD; cobalt-zinc-cadmium efflux system protein
D SPHFLASMR4Y_01919 ZIP family metal transporter K07238 TC.ZIP; zinc transporter, ZIP family
D SPHFLASMR4Y_02933 cnrA; nickel and cobalt resistance protein CnrA K15726 czcA; heavy metal efflux system protein
D SPHFLASMR4Y_02926 cusA; cation efflux system protein CusA K07787 cusA; copper/silver efflux system protein
D SPHFLASMR4Y_00789 acrB; multidrug efflux pump subunit AcrB K18138 acrB; multidrug efflux pump
D SPHFLASMR4Y_03397 eamA; putative amino-acid metabolite efflux pump K15268 eamA; O-acetylserine/cysteine efflux transporter
D SPHFLASMR4Y_02485 EamA-like transporter family protein K05786 rarD; chloramphenicol-sensitive protein RarD
D SPHFLASMR4Y_02922 membrane protein K09771 TC.SMR3; small multidrug resistance family-3 protein
D SPHFLASMR4Y_00584 yrbG; inner membrane protein YrbG K07301 yrbG; cation:H+ antiporter
D SPHFLASMR4Y_02842 actP; cation acetate symporter K14393 actP; cation/acetate symporter
D SPHFLASMR4Y_01788 nhaA; sodium:proton antiporter K03313 nhaA; Na+:H+ antiporter, NhaA family
D SPHFLASMR4Y_01987 nhaA; sodium:proton antiporter K03313 nhaA; Na+:H+ antiporter, NhaA family
D SPHFLASMR4Y_00190 kefC; glutathione-regulated potassium-efflux system protein KefC K11747 kefB; glutathione-regulated potassium-efflux system protein KefB
D SPHFLASMR4Y_01306 kefC; glutathione-regulated potassium-efflux system protein KefC K03455 KEA1_2_3; K+:H+ antiporter
D SPHFLASMR4Y_02592 codB; cytosine permease K10974 codB; cytosine permease
D SPHFLASMR4Y_01274 dauA; C4-dicarboxylic acid transporter DauA K03321 TC.SULP; sulfate permease, SulP family
D SPHFLASMR4Y_02162 putative sulfate transporter K03321 TC.SULP; sulfate permease, SulP family
D SPHFLASMR4Y_03222 bicA; bicarbonate transporter BicA K03321 TC.SULP; sulfate permease, SulP family
D SPHFLASMR4Y_01284 mntH; divalent metal cation transporter MntH K03322 mntH; manganese transport protein
D SPHFLASMR4Y_02708 acr3; arsenical-resistance protein Acr3 K03325 ACR3; arsenite transporter
D SPHFLASMR4Y_02496 murJ; putative lipid II flippase MurJ K03980 murJ; putative peptidoglycan lipid II flippase
D SPHFLASMR4Y_01266 trkD; potassium transport protein Kup K03549 kup; KUP system potassium uptake protein
D SPHFLASMR4Y_02015 rhtB; homoserine/homoserine lactone efflux protein K05834 rhtB; homoserine/homoserine lactone efflux protein
D SPHFLASMR4Y_01001 yhhQ; inner membrane protein YhhQ K09125 yhhQ; queuosine precursor transporter
D SPHFLASMR4Y_02330 membrane protein K09125 yhhQ; queuosine precursor transporter
D SPHFLASMR4Y_01570 membrane protein K05595 marC; multiple antibiotic resistance protein
D SPHFLASMR4Y_00088 ftsW; putative lipid II flippase FtsW K03588 ftsW; cell division protein FtsW
D SPHFLASMR4Y_02240 membrane protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D SPHFLASMR4Y_01194 mntP; putative manganese efflux pump MntP K23242 mntP; manganese efflux pump family protein
D SPHFLASMR4Y_02907 mntP; putative manganese efflux pump MntP K23242 mntP; manganese efflux pump family protein
D SPHFLASMR4Y_02169 energy transducer TonB K03832 tonB; periplasmic protein TonB
D SPHFLASMR4Y_01650 energy transducer TonB K03832 tonB; periplasmic protein TonB
D SPHFLASMR4Y_02888 energy transducer TonB K03832 tonB; periplasmic protein TonB
D SPHFLASMR4Y_02412 transport protein TonB K03832 tonB; periplasmic protein TonB
D SPHFLASMR4Y_03299 outer membrane lipoprotein Omp16 K03640 pal; peptidoglycan-associated lipoprotein
D SPHFLASMR4Y_02874 outer membrane lipoprotein Omp16 K03640 pal; peptidoglycan-associated lipoprotein
D SPHFLASMR4Y_03300 tolB; translocation protein TolB K03641 tolB; TolB protein
D SPHFLASMR4Y_00036 hppA; sodium-translocating pyrophosphatase K15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]
D SPHFLASMR4Y_00856 emrA; multidrug export protein EmrA K03543 emrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_02934 cnrB; nickel and cobalt resistance protein CnrB K15727 czcB; membrane fusion protein, heavy metal efflux system
D SPHFLASMR4Y_02925 cusB; cation efflux system protein CusB K07798 cusB; membrane fusion protein, copper/silver efflux system
D SPHFLASMR4Y_01662 prsE; type I secretion system membrane fusion protein PrsE K12542 lapC; membrane fusion protein, adhesin transport system
D SPHFLASMR4Y_00788 acrA; multidrug efflux pump subunit AcrA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_02021 mdtA; multidrug resistance protein MdtA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_02420 ptk; tyrosine-protein kinase ptk K16554 exoP; polysaccharide biosynthesis transport protein [EC:2.7.10.3]
D SPHFLASMR4Y_00985 yveL; putative tyrosine-protein kinase YveL K00903 epsB; protein-tyrosine kinase [EC:2.7.10.3]
D SPHFLASMR4Y_00986 chain length determinant protein K25590 epsF; protein tyrosine kinase modulator
D SPHFLASMR4Y_03336 FeoA domain protein K04758 feoA; ferrous iron transport protein A
D SPHFLASMR4Y_03337 feoB; ferrous iron transport protein B K04759 feoB; ferrous iron transport protein B
D SPHFLASMR4Y_02893 crtK-2; tryptophan-rich protein TspO K05770 TSPO; translocator protein
D SPHFLASMR4Y_01270 ccmF; cytochrome c-type biogenesis protein CcmF K02198 ccmF; cytochrome c-type biogenesis protein CcmF
D SPHFLASMR4Y_03186 putative Mg(2+) transport ATPase K07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein
D SPHFLASMR4Y_00469 MltA-interacting protein MipA K07274 mipA; MipA family protein
C 02044 Secretion system [BR:sfla02044]
D SPHFLASMR4Y_03160 bepC; outer membrane efflux protein BepC K12340 tolC; outer membrane protein
D SPHFLASMR4Y_01664 glnQ; glutamine ABC transporter ATP-binding protein K12541 lapB; ATP-binding cassette, subfamily C, bacterial LapB
D SPHFLASMR4Y_01662 prsE; type I secretion system membrane fusion protein PrsE K12542 lapC; membrane fusion protein, adhesin transport system
D SPHFLASMR4Y_01665 bepC; outer membrane efflux protein BepC K12543 lapE; outer membrane protein, adhesin transport system
D SPHFLASMR4Y_03065 epsC; type II secretion system protein C K02452 gspC; general secretion pathway protein C
D SPHFLASMR4Y_03066 xcpQ; type II secretion system protein D K02453 gspD; general secretion pathway protein D
D SPHFLASMR4Y_03067 epsE; type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
D SPHFLASMR4Y_03166 epsE; type II secretion system protein E K02454 gspE; general secretion pathway protein E [EC:7.4.2.8]
D SPHFLASMR4Y_03068 epsF; type II secretion system protein F K02455 gspF; general secretion pathway protein F
D SPHFLASMR4Y_03069 xcpT; type II secretion system protein G K02456 gspG; general secretion pathway protein G
D SPHFLASMR4Y_02669 type II secretion system protein GspH K02457 gspH; general secretion pathway protein H
D SPHFLASMR4Y_02670 type II secretion system (T2SS), protein I K02458 gspI; general secretion pathway protein I
D SPHFLASMR4Y_01282 xcpW; type II secretion system protein J K02459 gspJ; general secretion pathway protein J
D SPHFLASMR4Y_01281 gspK; putative type II secretion system protein K K02460 gspK; general secretion pathway protein K
D SPHFLASMR4Y_03071 type II secretion system (T2SS), protein M K02462 gspM; general secretion pathway protein M
D SPHFLASMR4Y_01790 type II secretion system (T2SS), protein N K02463 gspN; general secretion pathway protein N
D SPHFLASMR4Y_00674 pppA; leader peptidase PppA K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D SPHFLASMR4Y_00055 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D SPHFLASMR4Y_01670 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D SPHFLASMR4Y_00054 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D SPHFLASMR4Y_01682 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D SPHFLASMR4Y_00053 xpsD; type II secretion system protein D K02280 cpaC; pilus assembly protein CpaC
D SPHFLASMR4Y_01681 pulD; type II secretion system protein D K02280 cpaC; pilus assembly protein CpaC
D SPHFLASMR4Y_00052 pilus biogenesis CpaD protein (pilus_cpaD) K02281 cpaD; pilus assembly protein CpaD
D SPHFLASMR4Y_00051 iron-sulfur cluster carrier protein K02282 cpaE; pilus assembly protein CpaE
D SPHFLASMR4Y_01676 AAA domain protein K02282 cpaE; pilus assembly protein CpaE
D SPHFLASMR4Y_00129 putative conjugal transfer protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D SPHFLASMR4Y_01675 putative conjugal transfer protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D SPHFLASMR4Y_00050 type II secretion system (T2SS), protein F K12510 tadB; tight adherence protein B
D SPHFLASMR4Y_01674 type II secretion system (T2SS), protein F K12510 tadB; tight adherence protein B
D SPHFLASMR4Y_00049 type II secretion system (T2SS), protein F K12511 tadC; tight adherence protein C
D SPHFLASMR4Y_01673 type II secretion system (T2SS), protein F K12511 tadC; tight adherence protein C
D SPHFLASMR4Y_01683 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00199 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00200 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_01573 YGGT family protein K02221 yggT; YggT family protein
D SPHFLASMR4Y_01095 comEC; ComE operon protein 3 K02238 comEC; competence protein ComEC
D SPHFLASMR4Y_00230 flhA; flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA
D SPHFLASMR4Y_00383 conjugal transfer protein TraG K12056 traG; conjugal transfer mating pair stabilization protein TraG
D SPHFLASMR4Y_00385 F plasmid transfer operon protein K12057 traF; conjugal transfer pilus assembly protein TraF
D SPHFLASMR4Y_00386 conjugal transfer mating pair stabilization protein TraN K12058 traN; conjugal transfer mating pair stabilization protein TraN
D SPHFLASMR4Y_00387 type-F conjugative transfer system pilin assembly protein K12059 trbC; conjugal transfer pilus assembly protein TrbC
D SPHFLASMR4Y_00388 TraU protein K12060 traU; conjugal transfer pilus assembly protein TraU
D SPHFLASMR4Y_00389 TraW: type-F conjugative transfer system protein TraW K12061 traW; conjugal transfer pilus assembly protein TraW
D SPHFLASMR4Y_00390 signal peptidase, peptidase S26 K12062 trbI; conjugal transfer pilin signal peptidase TrbI
D SPHFLASMR4Y_00393 virB4; type IV secretion system protein virB4 K12063 traC; conjugal transfer ATP-binding protein TraC
D SPHFLASMR4Y_00394 TraV: type IV conjugative transfer system protein TraV K12064 traV; conjugal transfer pilus assembly protein TraV
D SPHFLASMR4Y_00396 bacterial conjugation TrbI-like protein K12065 traB; conjugal transfer pilus assembly protein TraB
D SPHFLASMR4Y_00397 TraK protein K12066 traK; conjugal transfer pilus assembly protein TraK
D SPHFLASMR4Y_00398 TraE protein K12067 traE; conjugal transfer pilus assembly protein TraE
D SPHFLASMR4Y_00399 TraL protein K12068 traL; conjugal transfer pilus assembly protein TraL
D SPHFLASMR4Y_00400 membrane protein K12069 traA; conjugal transfer pilus assembly protein TraA
D SPHFLASMR4Y_00395 dsbC; thiol:disulfide interchange protein DsbC K03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]
D SPHFLASMR4Y_00384 conjugative relaxosome accessory transposon protein K12072 traH; conjugative transfer pilus assembly protein TraH
D SPHFLASMR4Y_01556 putative fimbrial chaperone protein K07346 fimC; fimbrial chaperone protein
D SPHFLASMR4Y_01557 caf1A; F1 capsule-anchoring protein K07347 fimD; outer membrane usher protein
D SPHFLASMR4Y_01555 spore Coat Protein U domain protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
D SPHFLASMR4Y_01057 preprotein translocase subunit SecA K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D SPHFLASMR4Y_02497 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D SPHFLASMR4Y_01371 preprotein translocase subunit SecD K03072 secD; preprotein translocase subunit SecD
D SPHFLASMR4Y_01996 preprotein translocase subunit SecE K03073 secE; preprotein translocase subunit SecE
D SPHFLASMR4Y_01370 preprotein translocase subunit SecF K03074 secF; preprotein translocase subunit SecF
D SPHFLASMR4Y_01078 preprotein translocase subunit SecG K03075 secG; preprotein translocase subunit SecG
D SPHFLASMR4Y_01416 preprotein translocase subunit SecY K03076 secY; preprotein translocase subunit SecY
D SPHFLASMR4Y_00864 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SPHFLASMR4Y_00868 ftsY; signal recognition particle receptor FtsY K03110 ftsY; fused signal recognition particle receptor
D SPHFLASMR4Y_01372 preprotein translocase subunit YajC K03210 yajC; preprotein translocase subunit YajC
D SPHFLASMR4Y_02504 yidC; membrane protein insertase YidC K03217 yidC; YidC/Oxa1 family membrane protein insertase
D SPHFLASMR4Y_00068 tatA; Sec-independent protein translocase protein TatA K03116 tatA; sec-independent protein translocase protein TatA
D SPHFLASMR4Y_00069 tatB; Sec-independent protein translocase protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D SPHFLASMR4Y_00070 tatC; Sec-independent protein translocase protein TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:sfla02042]
D SPHFLASMR4Y_03348 corC; magnesium and cobalt efflux protein CorC K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:sfla02022]
D SPHFLASMR4Y_00716 phoR; alkaline phosphatase synthesis sensor protein PhoR K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
D SPHFLASMR4Y_00710 fixJ; DNA-binding response regulator K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
D SPHFLASMR4Y_02876 kdpD; sensor protein KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
D SPHFLASMR4Y_02875 fixJ; DNA-binding response regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
D SPHFLASMR4Y_00966 baeS; signal transduction histidine-protein kinase BaeS K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
D SPHFLASMR4Y_00965 fixJ; DNA-binding response regulator K14981 chvI; two-component system, OmpR family, response regulator ChvI
D SPHFLASMR4Y_00752 fixJ; DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
D SPHFLASMR4Y_01361 fixJ; DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
D SPHFLASMR4Y_00306 fixJ; DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
D SPHFLASMR4Y_02054 fixJ; DNA-binding response regulator K08083 algR; two-component system, LytTR family, response regulator AlgR
D SPHFLASMR4Y_02053 yehU; sensor histidine kinase YehU K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
D SPHFLASMR4Y_03011 ypdA; sensor histidine kinase YpdA K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
D SPHFLASMR4Y_01965 fixJ; DNA-binding response regulator K02477 K02477; two-component system, LytTR family, response regulator
D SPHFLASMR4Y_00768 glnL; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
D SPHFLASMR4Y_00769 fixJ; DNA-binding response regulator K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
D SPHFLASMR4Y_00770 kinB; alginate biosynthesis sensor protein KinB K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D SPHFLASMR4Y_00771 fixJ; DNA-binding response regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D SPHFLASMR4Y_02243 fixJ; DNA-binding response regulator K11443 divK; two-component system, cell cycle response regulator DivK
D SPHFLASMR4Y_01311 fixJ; DNA-binding response regulator K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
D SPHFLASMR4Y_00652 fixJ; DNA-binding response regulator K13584 ctrA; two-component system, cell cycle response regulator CtrA
D SPHFLASMR4Y_02787 fixJ; DNA-binding response regulator K13589 cpdR; two-component system, cell cycle response regulator CpdR
D SPHFLASMR4Y_00245 fixL; sensor protein FixL K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
D SPHFLASMR4Y_00246 fixJ; DNA-binding response regulator K14987 fixJ; two-component system, LuxR family, response regulator FixJ
D SPHFLASMR4Y_01148 rpfC; sensory/regulatory protein RpfC K10715 rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]
D SPHFLASMR4Y_01907 histidine phosphotransferase K20976 hptB; histidine phosphotransfer protein HptB
D SPHFLASMR4Y_02539 nrtA; nitrate transport protein NrtA K22067 nasS; two-component system, oxyanion-binding sensor
D SPHFLASMR4Y_02538 pdtaR; putative transcriptional regulatory protein pdtaR K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
C 02035 Bacterial motility proteins [BR:sfla02035]
D SPHFLASMR4Y_00230 flhA; flagellar biosynthesis protein FlhA K02400 flhA; flagellar biosynthesis protein FlhA
D SPHFLASMR4Y_00231 lafS; RNA polymerase sigma factor for flagellar operon K02405 fliA; RNA polymerase sigma factor FliA
D SPHFLASMR4Y_00233 zraR; transcriptional regulatory protein ZraR K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein
D SPHFLASMR4Y_00674 pppA; leader peptidase PppA K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
D SPHFLASMR4Y_01683 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00199 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00200 Flp/Fap pilin component K02651 flp; pilus assembly protein Flp/PilA
D SPHFLASMR4Y_00055 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D SPHFLASMR4Y_01670 type IV leader peptidase family protein K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]
D SPHFLASMR4Y_00054 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D SPHFLASMR4Y_01682 Flp pilus assembly protein RcpC/CpaB K02279 cpaB; pilus assembly protein CpaB
D SPHFLASMR4Y_00053 xpsD; type II secretion system protein D K02280 cpaC; pilus assembly protein CpaC
D SPHFLASMR4Y_01681 pulD; type II secretion system protein D K02280 cpaC; pilus assembly protein CpaC
D SPHFLASMR4Y_00052 pilus biogenesis CpaD protein (pilus_cpaD) K02281 cpaD; pilus assembly protein CpaD
D SPHFLASMR4Y_00051 iron-sulfur cluster carrier protein K02282 cpaE; pilus assembly protein CpaE
D SPHFLASMR4Y_01676 AAA domain protein K02282 cpaE; pilus assembly protein CpaE
D SPHFLASMR4Y_00129 putative conjugal transfer protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D SPHFLASMR4Y_01675 putative conjugal transfer protein K02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]
D SPHFLASMR4Y_01556 putative fimbrial chaperone protein K07346 fimC; fimbrial chaperone protein
D SPHFLASMR4Y_01557 caf1A; F1 capsule-anchoring protein K07347 fimD; outer membrane usher protein
D SPHFLASMR4Y_01555 spore Coat Protein U domain protein K27078 cupE; spore coat protein U domain-containing protein, fimbrial subunit CupE1/2/3/6
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:sfla04812]
D SPHFLASMR4Y_00943 dnaK; molecular chaperone DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D SPHFLASMR4Y_02652 dnaK; molecular chaperone DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D SPHFLASMR4Y_00096 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D SPHFLASMR4Y_00095 ftsA; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D SPHFLASMR4Y_00907 AAA domain protein K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_02307 parA; chromosome partitioning protein ParA K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_02251 soj; sporulation initiation inhibitor protein Soj K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_01977 soj; sporulation initiation inhibitor protein Soj K03496 parA; chromosome partitioning protein
D SPHFLASMR4Y_02308 parB; chromosome-partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D SPHFLASMR4Y_00358 spo0C; chromosome-partitioning protein Spo0J K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
C 04147 Exosome [BR:sfla04147]
D SPHFLASMR4Y_01130 fda; fructose-bisphosphate aldolase class 1 K01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SPHFLASMR4Y_01025 eno; phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SPHFLASMR4Y_01132 gapA; type I glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D SPHFLASMR4Y_01131 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D SPHFLASMR4Y_02219 ttuE; pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SPHFLASMR4Y_01535 membrane dipeptidase (peptidase family M19) K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D SPHFLASMR4Y_03371 membrane dipeptidase (peptidase family M19) K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D SPHFLASMR4Y_02157 prxU; selenocysteine-containing peroxiredoxin PrxU K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D SPHFLASMR4Y_02177 groEL; molecular chaperone GroEL K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D SPHFLASMR4Y_00173 dnaK; molecular chaperone DnaK K04043 dnaK; molecular chaperone DnaK
D SPHFLASMR4Y_00822 pgi; glucose-6-phosphate isomerase K01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]
D SPHFLASMR4Y_03063 gnl; gluconolactonase K01053 gnl; gluconolactonase [EC:3.1.1.17]
D SPHFLASMR4Y_01245 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D SPHFLASMR4Y_01438 tuf; elongation factor Tu K02358 tuf; elongation factor Tu
D SPHFLASMR4Y_03294 ftsH3; ATP-dependent zinc metalloprotease FtsH 3 K13525 VCP; transitional endoplasmic reticulum ATPase
D SPHFLASMR4Y_03092 purine nucleoside phosphoramidase K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D SPHFLASMR4Y_00525 sodium:proton symporter K14347 SLC10A7; solute carrier family 10 (sodium/bile acid cotransporter), member 7
D SPHFLASMR4Y_02962 prpE; propionate--CoA ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00456 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02365 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_02372 prpE; propionyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_03215 prpE; acyl-CoA synthetase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SPHFLASMR4Y_00673 thlA; acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00791 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02322 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02770 fadA; 3-ketoacyl-CoA thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02675 fadA; putative acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_02685 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SPHFLASMR4Y_00851 angiotensin-converting enzyme K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
D SPHFLASMR4Y_00847 ahcY; adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D SPHFLASMR4Y_01415 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D SPHFLASMR4Y_02004 apt; adenine phosphoribosyltransferase K00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]
D SPHFLASMR4Y_02762 fumC; class II fumarate hydratase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D SPHFLASMR4Y_00583 argG; argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D SPHFLASMR4Y_00745 glpK; glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D SPHFLASMR4Y_01516 glnA; glutamine synthetase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SPHFLASMR4Y_02036 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D SPHFLASMR4Y_02690 hpd; 4-hydroxyphenylpyruvate dioxygenase K00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]
D SPHFLASMR4Y_01631 phhB; putative pterin-4-alpha-carbinolamine dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D SPHFLASMR4Y_02063 serA; D-3-phosphoglycerate dehydrogenase K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D SPHFLASMR4Y_01541 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D SPHFLASMR4Y_00804 lpd; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_00949 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02101 pdhD; dihydrolipoyl dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02189 gltD; glutamate synthase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SPHFLASMR4Y_02471 etfA; electron transfer flavoprotein subunit alpha K03522 fixB; electron transfer flavoprotein alpha subunit
D SPHFLASMR4Y_01079 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SPHFLASMR4Y_01530 gpmA; phosphoglyceromutase K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
C 02048 Prokaryotic defense system [BR:sfla02048]
D SPHFLASMR4Y_01613 hypothetical protein K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D SPHFLASMR4Y_01614 hsdM; type I restriction enzyme EcoKI M protein K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D SPHFLASMR4Y_00640 dpnA; modification methylase DpnIIB K13581 ccrM; modification methylase [EC:2.1.1.72]
D SPHFLASMR4Y_01499 hpaIIM; modification methylase HpaII K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SPHFLASMR4Y_01500 hypothetical protein K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
D SPHFLASMR4Y_03178 ParE toxin of type II toxin-antitoxin system, parDE K06218 relE; mRNA interferase RelE/StbE
D SPHFLASMR4Y_00876 DNA-binding transcriptional activator PspC K03973 pspC; phage shock protein C
D SPHFLASMR4Y_01459 DNA-binding transcriptional activator PspC K03973 pspC; phage shock protein C
D SPHFLASMR4Y_00875 pspB; phage shock protein B K03970 pspB; phage shock protein B
D SPHFLASMR4Y_03362 CcdB protein K19163 ccdB; toxin CcdB
D SPHFLASMR4Y_01508 parE1; toxin ParE1 K19092 parE1_3_4; toxin ParE1/3/4
D SPHFLASMR4Y_01182 ParE toxin of type II toxin-antitoxin system, parDE K19092 parE1_3_4; toxin ParE1/3/4
D SPHFLASMR4Y_00096 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D SPHFLASMR4Y_00943 dnaK; molecular chaperone DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D SPHFLASMR4Y_02652 dnaK; molecular chaperone DnaK K03569 mreB; rod shape-determining protein MreB and related proteins
D SPHFLASMR4Y_02837 parC; DNA topoisomerase 4 subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D SPHFLASMR4Y_01175 parE; DNA topoisomerase 4 subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D SPHFLASMR4Y_01096 gltX; glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_02411 gltX1; glutamate--tRNA ligase 1 K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SPHFLASMR4Y_01049 flavinator of succinate dehydrogenase K09159 cptB; antitoxin CptB
D SPHFLASMR4Y_00959 iscS; cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D SPHFLASMR4Y_00960 iscS; IscS-like cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:sfla04090]
D SPHFLASMR4Y_00851 angiotensin-converting enzyme K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
C 01504 Antimicrobial resistance genes [BR:sfla01504]
D SPHFLASMR4Y_00455 emrB; DSBA oxidoreductase K08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein
D SPHFLASMR4Y_03235 mecR1; methicillin resistance mecR1 protein K02172 blaR1; bla regulator protein blaR1
D SPHFLASMR4Y_03234 blaI; penicillinase repressor K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
D SPHFLASMR4Y_03323 smeA; carbapenem-hydrolyzing beta-lactamase Sme-1 K17836 penP; beta-lactamase class A [EC:3.5.2.6]
D SPHFLASMR4Y_00788 acrA; multidrug efflux pump subunit AcrA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_02021 mdtA; multidrug resistance protein MdtA K03585 acrA; membrane fusion protein, multidrug efflux system
D SPHFLASMR4Y_00789 acrB; multidrug efflux pump subunit AcrB K18138 acrB; multidrug efflux pump
D SPHFLASMR4Y_00790 ttgI; toluene efflux pump outer membrane protein TtgI K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_01635 oprM; outer membrane protein OprM K18139 oprM; outer membrane protein, multidrug efflux system
D SPHFLASMR4Y_01634 DNA-binding transcriptional repressor AcrR K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
D SPHFLASMR4Y_03160 bepC; outer membrane efflux protein BepC K12340 tolC; outer membrane protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:sfla00537]
D SPHFLASMR4Y_01535 membrane dipeptidase (peptidase family M19) K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D SPHFLASMR4Y_03371 membrane dipeptidase (peptidase family M19) K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:sfla03100]
D SPHFLASMR4Y_01476 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SPHFLASMR4Y_03258 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SPHFLASMR4Y_01484 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SPHFLASMR4Y_00207 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_01002 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_02725 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_00929 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SPHFLASMR4Y_01054 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D SPHFLASMR4Y_01137 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D SPHFLASMR4Y_03162 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D SPHFLASMR4Y_02898 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SPHFLASMR4Y_00535 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SPHFLASMR4Y_02880 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D SPHFLASMR4Y_00747 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SPHFLASMR4Y_01560 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SPHFLASMR4Y_01280 tRNA-His K14226 tRNA-His; tRNA His
D SPHFLASMR4Y_01477 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D SPHFLASMR4Y_01485 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D SPHFLASMR4Y_00675 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_02385 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_00897 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_03251 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_02536 tRNA-Ser K14228 tRNA-Leu; tRNA Leu
D SPHFLASMR4Y_00434 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SPHFLASMR4Y_00948 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SPHFLASMR4Y_01006 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_01473 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_00996 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_01481 tRNA-Met K14230 tRNA-Met; tRNA Met
D SPHFLASMR4Y_03095 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D SPHFLASMR4Y_01373 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SPHFLASMR4Y_01146 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SPHFLASMR4Y_01005 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SPHFLASMR4Y_00784 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_02417 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_02224 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_01161 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SPHFLASMR4Y_01763 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SPHFLASMR4Y_02086 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SPHFLASMR4Y_00678 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SPHFLASMR4Y_01992 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D SPHFLASMR4Y_01621 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D SPHFLASMR4Y_02758 tRNA-Val K14237 tRNA-Val; tRNA Val
D SPHFLASMR4Y_02786 tRNA-Val K14237 tRNA-Val; tRNA Val
D SPHFLASMR4Y_01478 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D SPHFLASMR4Y_01475 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D SPHFLASMR4Y_01474 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D SPHFLASMR4Y_00957 bacterial small SRP K01983 ffs; SRP RNA
D SPHFLASMR4Y_00885 RNaseP_bact_a K01978 rnpB; M1 RNA
D SPHFLASMR4Y_01349 ssrA; transfer-messenger RNA, SsrA K15035 ssrA; transfer-messenger RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D SPHFLASMR4Y_01943 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha K21416 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-]
D SPHFLASMR4Y_00262 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha K21416 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-]
D SPHFLASMR4Y_01944 bfmBAB; 2-oxoisovalerate dehydrogenase subunit beta K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-]
D SPHFLASMR4Y_00261 bfmBAB; 2-oxoisovalerate dehydrogenase subunit beta K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-]
D SPHFLASMR4Y_00161 yliI; soluble aldose sugar dehydrogenase YliI K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]
D SPHFLASMR4Y_02852 yliI; soluble aldose sugar dehydrogenase YliI K21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]
D SPHFLASMR4Y_01514 qbdA; quinohemoprotein alcohol dehydrogenase ADH IIB K17760 qheDH; quinohemoprotein ethanol dehydrogenase [EC:1.1.9.1]
D SPHFLASMR4Y_00272 gabD; NAD-dependent succinate-semialdehyde dehydrogenase K00154 E1.2.1.68; coniferyl-aldehyde dehydrogenase [EC:1.2.1.68]
D SPHFLASMR4Y_03184 fadH; NADPH-dependent 2,4-dienoyl-CoA reductase K00219 fadH; 2,4-dienoyl-CoA reductase (NADPH2) [EC:1.3.1.34]
D SPHFLASMR4Y_01974 iorA; isoquinoline 1-oxidoreductase subunit alpha K07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]
D SPHFLASMR4Y_02334 iorA; isoquinoline 1-oxidoreductase subunit alpha K07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]
D SPHFLASMR4Y_01827 iorB; isoquinoline 1-oxidoreductase subunit beta K07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]
D SPHFLASMR4Y_02333 iorB; isoquinoline 1-oxidoreductase subunit beta K07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]
D SPHFLASMR4Y_00345 fadE; acyl-CoA dehydrogenase K18244 mmgC; acyl-CoA dehydrogenase [EC:1.3.99.-]
D SPHFLASMR4Y_00832 carboxynorspermidine synthase K27502 capadh; carboxyaminopropylagmatine dehydrogenase [EC:1.5.1.55]
D SPHFLASMR4Y_00844 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 ETFDH; electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1]
D SPHFLASMR4Y_00681 ppsC; phthiocerol synthesis polyketide synthase type I PpsC K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D SPHFLASMR4Y_02364 2-haloacrylate reductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D SPHFLASMR4Y_03230 alcohol dehydrogenase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D SPHFLASMR4Y_02175 zinc-type alcohol dehydrogenase-like protein K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D SPHFLASMR4Y_00450 ppsC; phthiocerol synthesis polyketide synthase type I PpsC K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D SPHFLASMR4Y_02556 2-haloacrylate reductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D SPHFLASMR4Y_02663 nitronate monooxygenase K23948 E1.6.5.9; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D SPHFLASMR4Y_02012 azoR; FMN-dependent NADH-azoreductase K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]
D SPHFLASMR4Y_02100 azoR1; FMN-dependent NADH-azoreductase 1 K01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]
D SPHFLASMR4Y_01548 ahpF; alkyl hydroperoxide reductase subunit F K03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-]
D SPHFLASMR4Y_02019 msrA; peptide methionine sulfoxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D SPHFLASMR4Y_03192 msrA; peptide methionine sulfoxide reductase MsrA K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D SPHFLASMR4Y_01781 msrB; peptide methionine sulfoxide reductase MsrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D SPHFLASMR4Y_02280 msrB; peptide methionine sulfoxide reductase MsrB K07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]
D SPHFLASMR4Y_03142 yfcG; disulfide-bond oxidoreductase YfcG K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-]
D SPHFLASMR4Y_02680 yghU; disulfide-bond oxidoreductase YghU K11209 yghU; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-]
D SPHFLASMR4Y_00381 ccp; cytochrome c551 peroxidase K00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]
D SPHFLASMR4Y_01880 bcp; putative peroxiredoxin K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D SPHFLASMR4Y_01576 bcp; putative peroxiredoxin bcp K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D SPHFLASMR4Y_00999 putative peroxiredoxin K24157 prxII; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D SPHFLASMR4Y_01511 alkyl hydroperoxide reductase subunit C K24158 prx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D SPHFLASMR4Y_01547 ahpC; alkyl hydroperoxide reductase subunit C K24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26]
D SPHFLASMR4Y_02013 yhhW; quercetin 2,3-dioxygenase K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D SPHFLASMR4Y_02006 8'-apo-carotenoid 13,14-cleaving dioxygenase K21822 E1.13.11.82; 8'-apo-carotenoid 13,14-cleaving dioxygenase [EC:1.13.11.82]
D SPHFLASMR4Y_01224 aspartyl/Asparaginyl beta-hydroxylase K22616 olsC; ornithine lipid ester-linked acyl 2-hydroxylase [EC:1.14.11.58]
D SPHFLASMR4Y_01648 PKHD-type hydroxylase K07336 K07336; PKHD-type hydroxylase [EC:1.14.11.-]
D SPHFLASMR4Y_03250 hsaA; flavin-dependent monooxygenase, oxygenase subunit HsaA K22027 iacA; indole-3-acetate monooxygenase [EC:1.14.13.235]
D SPHFLASMR4Y_00567 gltD; glutamate synthase K00528 fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D SPHFLASMR4Y_01976 arsC; arsenate reductase K00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]
D SPHFLASMR4Y_02707 arsC; glutaredoxin arsenate reductase K03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]
D SPHFLASMR4Y_03161 pcm; protein-L-isoaspartate O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D SPHFLASMR4Y_00581 cfa; cyclopropane-fatty-acyl-phospholipid synthase K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]
D SPHFLASMR4Y_01232 ufaA1; tuberculostearic acid methyltransferase UfaA1 K00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]
D SPHFLASMR4Y_00515 beta-ketodecanoyl-[acyl-carrier-protein] synthase K16872 E2.3.1.207; beta-ketodecanoyl-[acyl-carrier-protein] synthase [EC:2.3.1.207]
D SPHFLASMR4Y_02047 lnt; apolipoprotein N-acyltransferase K03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]
D SPHFLASMR4Y_00690 2-acyl-glycerophospho-ethanolamine acyltransferase K22617 olsA; lyso-ornithine lipid O-acyltransferase [EC:2.3.1.270]
D SPHFLASMR4Y_00494 acetyltransferase (GNAT) domain protein K03824 yhbS; putative acetyltransferase [EC:2.3.1.-]
D SPHFLASMR4Y_00669 ysnE; putative N-acetyltransferase YsnE K03829 yedL; putative acetyltransferase [EC:2.3.1.-]
D SPHFLASMR4Y_00648 arginyl-tRNA-protein transferase K21420 bpt; leucyl-tRNA---protein transferase [EC:2.3.2.29]
D SPHFLASMR4Y_00667 bshA; N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-]
D SPHFLASMR4Y_01584 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D SPHFLASMR4Y_02296 yqfL; putative pyruvate, phosphate dikinase regulatory protein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]
D SPHFLASMR4Y_01881 glnE; glutamate-ammonia-ligase adenylyltransferase K00982 glnE; [glutamine synthetase] adenylyltransferase / [glutamine synthetase]-adenylyl-L-tyrosine phosphorylase [EC:2.7.7.42 2.7.7.89]
D SPHFLASMR4Y_01619 reverse transcriptase (RNA-dependent DNA polymerase) K00986 ltrA; RNA-directed DNA polymerase [EC:2.7.7.49]
D SPHFLASMR4Y_00665 selenoprotein O and cysteine protein K08997 SELENOO; protein adenylyltransferase [EC:2.7.7.108]
D SPHFLASMR4Y_00375 dncV; cyclic GMP-AMP synthase K25555 dncV; cyclic GMP-AMP synthase [EC:2.7.7.-]
D SPHFLASMR4Y_02133 yfdE; acetyl-CoA:oxalate CoA-transferase K18702 uctC; CoA:oxalate CoA-transferase [EC:2.8.3.19]
D SPHFLASMR4Y_02346 smtB; succinyl-CoA--L-malate CoA-transferase beta subunit K18313 sct; succinyl-CoA---D-citramalate CoA-transferase [EC:2.8.3.20]
D SPHFLASMR4Y_01319 2-(acetamidomethylene)succinate hydrolase K19311 lipV; lipase [EC:3.1.1.-]
D SPHFLASMR4Y_01523 1,4-dihydroxy-2-naphthoyl-CoA hydrolase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D SPHFLASMR4Y_01764 ybgC; acyl-CoA thioester hydrolase YbgC K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D SPHFLASMR4Y_01767 acyl-ACP thioesterase K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D SPHFLASMR4Y_01835 fadM; long-chain acyl-CoA thioesterase FadM K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D SPHFLASMR4Y_03304 ybgC; acyl-CoA thioesterase YbgC K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D SPHFLASMR4Y_03145 thioesterase-like superfamily protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D SPHFLASMR4Y_01156 putative hydrolase K15781 serB-plsC; putative phosphoserine phosphatase / 1-acylglycerol-3-phosphate O-acyltransferase [EC:3.1.3.3 2.3.1.51]
D SPHFLASMR4Y_02630 gpmA; phosphoglyceromutase K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]
D SPHFLASMR4Y_02667 yjcS; putative alkyl/aryl-sulfatase YjcS K25227 sdsA1; linear primary-alkylsulfatase [EC:3.1.6.21]
D SPHFLASMR4Y_00777 ycfH; putative metal-dependent hydrolase YcfH K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D SPHFLASMR4Y_00887 amiD; N-acetylmuramoyl-L-alanine amidase AmiD K01447 xlyAB; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D SPHFLASMR4Y_02257 ureC; urease subunit alpha K06015 E3.5.1.81; N-acyl-D-amino-acid deacylase [EC:3.5.1.81]
D SPHFLASMR4Y_00974 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D SPHFLASMR4Y_03373 glutaryl-7-aminocephalosporanic-acid acylase K07116 pvdQ; acyl-homoserine-lactone acylase [EC:3.5.1.97]
D SPHFLASMR4Y_00123 polysaccharide deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D SPHFLASMR4Y_00983 pgdA; peptidoglycan deacetylase K22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]
D SPHFLASMR4Y_00205 2-oxoglutaramate amidase K11206 NIT1; deaminated glutathione amidase [EC:3.5.1.128]
D SPHFLASMR4Y_00577 yabJ; 2-iminobutanoate/2-iminopropanoate deaminase K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D SPHFLASMR4Y_00838 nnr; bifunctional NAD(P)H-hydrate repair enzyme Nnr K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D SPHFLASMR4Y_02038 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase K01726 GAMMACA; gamma-carbonic anhydrase [EC:4.2.1.-]
D SPHFLASMR4Y_00423 prpE; propionyl-CoA synthetase K18688 fadD19; 3-oxocholest-4-en-26-oate---CoA ligase [EC:6.2.1.42]
D SPHFLASMR4Y_02314 prpE; propionyl-CoA synthetase K18688 fadD19; 3-oxocholest-4-en-26-oate---CoA ligase [EC:6.2.1.42]
D SPHFLASMR4Y_00793 prpE; propionyl-CoA synthetase K25775 casG; steroid-24-oyl-CoA synthetase [EC:6.2.1.-]
D SPHFLASMR4Y_01583 prpE; propionyl-CoA synthetase K25775 casG; steroid-24-oyl-CoA synthetase [EC:6.2.1.-]
D SPHFLASMR4Y_00249 copA; copper-exporting P-type ATPase A K01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]
D SPHFLASMR4Y_02931 cadA; putative cadmium-transporting ATPase K01534 zntA; Zn2+/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D SPHFLASMR4Y_02032 fdxA; ferredoxin-2 K05524 fdxA; ferredoxin
D SPHFLASMR4Y_02472 etfB; electron transfer flavoprotein subunit beta K03521 fixA; electron transfer flavoprotein beta subunit
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
D SPHFLASMR4Y_01775 CysZ-like protein K06203 cysZ; CysZ protein
D SPHFLASMR4Y_01455 cetB; 2-epi-5-epi-valiolone epimerase K08234 yaeR; glyoxylase I family protein
D SPHFLASMR4Y_02272 YggS family pyridoxal phosphate enzyme K06997 yggS; PLP dependent protein
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
D SPHFLASMR4Y_02752 ubiB; putative protein kinase UbiB K03688 ubiB; ubiquinone biosynthesis protein
D SPHFLASMR4Y_01901 coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 COQ4; ubiquinone biosynthesis protein COQ4
D SPHFLASMR4Y_00428 coenzyme Q (ubiquinone) biosynthesis protein Coq4 K18586 COQ4; ubiquinone biosynthesis protein COQ4
D SPHFLASMR4Y_03335 RpsU-divergently transcribed K18587 COQ9; ubiquinone biosynthesis protein COQ9
D SPHFLASMR4Y_00763 ratA; ribosome association toxin RatA K18588 COQ10; coenzyme Q-binding protein COQ10
C 99988 Secondary metabolism
C 99999 Others
D SPHFLASMR4Y_02182 DoxX K15977 K15977; putative oxidoreductase
D SPHFLASMR4Y_03404 DoxX K15977 K15977; putative oxidoreductase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D SPHFLASMR4Y_01981 cspC; cold shock-like protein CspC K03704 cspA; cold shock protein
D SPHFLASMR4Y_02237 cspA; cold shock protein CspA K03704 cspA; cold shock protein
D SPHFLASMR4Y_00510 cspA; cold shock protein CspA K03704 cspA; cold shock protein
D SPHFLASMR4Y_03385 glnB; nitrogen regulatory protein P-II K04752 glnK; nitrogen regulatory protein P-II 2
C 99974 Translation
D SPHFLASMR4Y_00294 ribonuclease K07576 K07576; metallo-beta-lactamase family protein
D SPHFLASMR4Y_02700 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated K07577 K07577; putative mRNA 3-end processing factor
C 99975 Protein processing
D SPHFLASMR4Y_01453 clpS; ATP-dependent Clp protease adapter protein ClpS K06891 clpS; ATP-dependent Clp protease adaptor protein ClpS
D SPHFLASMR4Y_00896 tig; trigger factor K03545 tig; trigger factor
D SPHFLASMR4Y_02060 msrQ; protein-methionine-sulfoxide reductase heme-binding subunit MsrQ K17247 msrQ; methionine sulfoxide reductase heme-binding subunit
D SPHFLASMR4Y_01647 msrQ; protein-methionine-sulfoxide reductase heme-binding subunit MsrQ K17247 msrQ; methionine sulfoxide reductase heme-binding subunit
D SPHFLASMR4Y_01313 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D SPHFLASMR4Y_02508 comM; competence protein ComM K07391 comM; magnesium chelatase family protein
D SPHFLASMR4Y_03369 2OG-Fe(II) oxygenase superfamily protein K07394 K07394; SM-20-related protein
D SPHFLASMR4Y_00562 proteasome subunit K07395 K07395; putative proteasome-type protease
D SPHFLASMR4Y_01470 XdhC Rossmann domain protein K07402 xdhC; xanthine dehydrogenase accessory factor
C 99976 Replication and repair
D SPHFLASMR4Y_01568 DNA repair protein RadC K03630 radC; DNA repair protein RadC
D SPHFLASMR4Y_01198 DNA repair protein K03630 radC; DNA repair protein RadC
D SPHFLASMR4Y_00226 DNA repair protein RadC K03630 radC; DNA repair protein RadC
D SPHFLASMR4Y_00973 DNA recombination protein RmuC K09760 rmuC; DNA recombination protein RmuC
D SPHFLASMR4Y_00147 YraN family protein K07460 yraN; putative endonuclease
D SPHFLASMR4Y_01817 GIY-YIG nuclease superfamily protein K07461 K07461; putative endonuclease
D SPHFLASMR4Y_03278 GIY-YIG nuclease superfamily protein K07461 K07461; putative endonuclease
D SPHFLASMR4Y_03241 GIY-YIG nuclease superfamily protein K07461 K07461; putative endonuclease
D SPHFLASMR4Y_00827 dprA; DNA processing protein DprA K04096 smf; DNA processing protein
D SPHFLASMR4Y_00683 rarA; replication-associated recombination protein A K07478 ycaJ; putative ATPase
D SPHFLASMR4Y_00356 toprim domain protein K06919 K06919; putative DNA primase/helicase
D SPHFLASMR4Y_00405 transposase DDE domain protein K07481 K07481; transposase, IS5 family
D SPHFLASMR4Y_00323 transposase K07483 K07483; transposase
D SPHFLASMR4Y_02359 transposase K07483 K07483; transposase
D SPHFLASMR4Y_03112 transposase K07483 K07483; transposase
D SPHFLASMR4Y_02913 transposase K07483 K07483; transposase
D SPHFLASMR4Y_02963 transposase K07483 K07483; transposase
D SPHFLASMR4Y_02972 transposase K07483 K07483; transposase
D SPHFLASMR4Y_00348 transposase K07483 K07483; transposase
D SPHFLASMR4Y_00349 HTH-like domain protein K07497 K07497; putative transposase
D SPHFLASMR4Y_00355 transposase K07497 K07497; putative transposase
D SPHFLASMR4Y_00322 integrase core domain protein K07497 K07497; putative transposase
D SPHFLASMR4Y_00350 integrase core domain protein K07497 K07497; putative transposase
D SPHFLASMR4Y_02914 integrase core domain protein K07497 K07497; putative transposase
D SPHFLASMR4Y_02964 integrase core domain protein K07497 K07497; putative transposase
D SPHFLASMR4Y_02971 integrase core domain protein K07497 K07497; putative transposase
D SPHFLASMR4Y_02358 integrase core domain protein K07497 K07497; putative transposase
D SPHFLASMR4Y_03111 integrase core domain protein K07497 K07497; putative transposase
C 99979 Viral proteins
C 99998 Others
D SPHFLASMR4Y_00874 pspA; phage shock protein A K03969 pspA; phage shock protein A
D SPHFLASMR4Y_00955 ybaB; nucleoid-associated protein YbaB K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D SPHFLASMR4Y_02580 melB; melibiose carrier protein K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family
D SPHFLASMR4Y_01809 yihP; putative 2,3-dihydroxypropane-1-sulfonate exporter K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family
D SPHFLASMR4Y_01398 yjmB; putative symporter YjmB K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family
D SPHFLASMR4Y_02579 yjmB; putative symporter YjmB K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family
D SPHFLASMR4Y_02587 yihP; putative 2,3-dihydroxypropane-1-sulfonate exporter K03292 TC.GPH; glycoside/pentoside/hexuronide:cation symporter, GPH family
D SPHFLASMR4Y_00795 betS; glycine betaine/proline betaine transporter BetS K03451 TC.BCT; betaine/carnitine transporter, BCCT family
D SPHFLASMR4Y_00630 dtpB; dipeptide and tripeptide permease B K03305 TC.POT; proton-dependent oligopeptide transporter, POT family
D SPHFLASMR4Y_00759 actP; cation acetate symporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D SPHFLASMR4Y_03387 sglT; sodium/glucose cotransporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D SPHFLASMR4Y_03093 sodium:neurotransmitter symporter family protein K03308 TC.NSS; neurotransmitter:Na+ symporter, NSS family
D SPHFLASMR4Y_02808 alsT; amino-acid carrier protein AlsT K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family
D SPHFLASMR4Y_00105 panS; pantothenate precursors transporter PanS K03453 TC.BASS; bile acid:Na+ symporter, BASS family
D SPHFLASMR4Y_01158 nupX; putative nucleoside permease NupX K03317 TC.CNT; concentrative nucleoside transporter, CNT family
D SPHFLASMR4Y_02328 nupX; putative nucleoside permease NupX K03317 TC.CNT; concentrative nucleoside transporter, CNT family
C 99978 Cell growth
D SPHFLASMR4Y_00869 yciB; intracellular septation protein K06190 ispZ; intracellular septation protein
D SPHFLASMR4Y_03096 hin; DNA-invertase hin K06400 spoIVCA; site-specific DNA recombinase
D SPHFLASMR4Y_02384 hin; DNA-invertase hin K06400 spoIVCA; site-specific DNA recombinase
D SPHFLASMR4Y_02515 envC; murein hydrolase activator EnvC K22719 envC; murein hydrolase activator
C 99993 Cell motility
C 99995 Signaling proteins
D SPHFLASMR4Y_00524 fusA; elongation factor G K06207 typA; GTP-binding protein
D SPHFLASMR4Y_00688 PhoH-like protein K06217 phoH; phosphate starvation-inducible protein PhoH and related proteins
C 99992 Structural proteins
D SPHFLASMR4Y_00656 acm; lysozyme M1 K07273 acm; lysozyme
D SPHFLASMR4Y_00170 ompW; outer membrane protein W K07275 ompW; outer membrane protein
D SPHFLASMR4Y_02833 TPR repeat-containing protein K07280 K07280; outer membrane protein
D SPHFLASMR4Y_01241 membrane protein K07283 ydiY; putative salt-induced outer membrane protein
D SPHFLASMR4Y_03127 AsmA family protein K07290 yhjG; AsmA family protein
D SPHFLASMR4Y_01248 ybbJ; inner membrane protein YbbJ K07340 ybbJ; inner membrane protein
D SPHFLASMR4Y_02081 mdtA; multidrug resistance protein MdtA K02005 ABC.CD.TX; HlyD family secretion protein
D SPHFLASMR4Y_00617 creD; inner membrane protein CreD K06143 creD; inner membrane protein
D SPHFLASMR4Y_01271 ccmE; cytochrome c-type biogenesis protein CcmE K02197 ccmE; cytochrome c-type biogenesis protein CcmE
D SPHFLASMR4Y_01815 formate-dependent nitrite reductase complex subunit NrfG K02200 ccmH; cytochrome c-type biogenesis protein CcmH
D SPHFLASMR4Y_01268 ccmH; cytochrome c-type biogenesis protein CcmH K02200 ccmH; cytochrome c-type biogenesis protein CcmH
D SPHFLASMR4Y_01267 tetratricopeptide repeat protein K02200 ccmH; cytochrome c-type biogenesis protein CcmH
D SPHFLASMR4Y_03329 cytoskeletal protein RodZ K15539 rodZ; cytoskeleton protein RodZ
C 99994 Others
D SPHFLASMR4Y_00546 phosphate transport system regulatory protein PhoU K02039 phoU; phosphate transport system protein
D SPHFLASMR4Y_00711 phosphate transport system regulatory protein PhoU K02039 phoU; phosphate transport system protein
D SPHFLASMR4Y_01905 bacterioferritin-associated ferredoxin K02192 bfd; bacterioferritin-associated ferredoxin
D SPHFLASMR4Y_01178 CO2+/MG2+ efflux protein ApaG K06195 apaG; ApaG protein
D SPHFLASMR4Y_00114 copB; copper resistance protein B K07233 pcoB; copper resistance protein B
D SPHFLASMR4Y_02953 copB; copper resistance protein B K07233 pcoB; copper resistance protein B
D SPHFLASMR4Y_02950 cnrR; nickel and cobalt resistance protein CnrR K24078 cnrR; nickel and cobalt resistance protein CnrR
B
B 09194 Poorly characterized
C 99996 General function prediction only
D SPHFLASMR4Y_00188 colicin V production protein K03558 cvpA; membrane protein required for colicin V production
D SPHFLASMR4Y_01641 ctb; group 3 truncated hemoglobin ctb K06886 glbN; hemoglobin
D SPHFLASMR4Y_02810 putative NTE family protein K07001 K07001; NTE family protein
D SPHFLASMR4Y_03384 putative NTE family protein K07001 K07001; NTE family protein
D SPHFLASMR4Y_02207 mtnC; enolase-phosphatase E1 K07025 K07025; putative hydrolase of the HAD superfamily
D SPHFLASMR4Y_03064 yihX; alpha-D-glucose 1-phosphate phosphatase YihX K07025 K07025; putative hydrolase of the HAD superfamily
D SPHFLASMR4Y_02462 sufB; FeS cluster assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D SPHFLASMR4Y_02464 sufD; FeS cluster assembly protein SufD K09015 sufD; Fe-S cluster assembly protein SufD
D SPHFLASMR4Y_01235 LexA-binding, inner membrane-associated putative hydrolase K07038 K07038; inner membrane protein
D SPHFLASMR4Y_01914 ybcI; inner membrane protein YbcI K07038 K07038; inner membrane protein
D SPHFLASMR4Y_02071 ribonuclease BN/unknown domain fusion protein K07058 K07058; membrane protein
D SPHFLASMR4Y_00882 csdE; sulfur acceptor protein CsdE K02426 sufE; cysteine desulfuration protein SufE
D SPHFLASMR4Y_02266 putative rhodanese-related sulfurtransferase K07146 K07146; UPF0176 protein
D SPHFLASMR4Y_00073 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K04750 phnB; PhnB protein
D SPHFLASMR4Y_01353 LemA family protein K03744 lemA; LemA protein
D SPHFLASMR4Y_02860 DNA polymerase III subunit gamma/tau K00389 yidH; putative membrane protein
D SPHFLASMR4Y_02522 bacterial PH domain protein K08981 K08981; putative membrane protein
D SPHFLASMR4Y_01449 hypothetical protein K08987 K08987; putative membrane protein
D SPHFLASMR4Y_01355 membrane protein K08988 K08988; putative membrane protein
D SPHFLASMR4Y_03189 alkylphosphonate utilization protein K06193 phnA; protein PhnA
C 99997 Function unknown
D SPHFLASMR4Y_02285 ankyrin repeats (3 copies) K06867 K06867; uncharacterized protein
D SPHFLASMR4Y_01354 TPM domain protein K06872 K06872; uncharacterized protein
D SPHFLASMR4Y_00438 ybhL; inner membrane protein YbhL K06890 K06890; uncharacterized protein
D SPHFLASMR4Y_00179 SnoaL-like domain protein K06893 K06893; uncharacterized protein
D SPHFLASMR4Y_01832 SnoaL-like domain protein K06893 K06893; uncharacterized protein
D SPHFLASMR4Y_02024 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K06923 K06923; uncharacterized protein
D SPHFLASMR4Y_01828 CoA binding domain protein K06929 K06929; uncharacterized protein
D SPHFLASMR4Y_01801 putative zinc-or iron-chelating domain protein K06940 K06940; uncharacterized protein
D SPHFLASMR4Y_02267 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated K06953 K06953; uncharacterized protein
D SPHFLASMR4Y_02626 protoporphyrinogen oxidase K06954 K06954; uncharacterized protein
D SPHFLASMR4Y_01410 doeB; N-alpha-acetyl-L-2,4-diaminobutyric acid deacetylase K06987 K06987; uncharacterized protein
D SPHFLASMR4Y_02049 glyoxalase K06991 K06991; uncharacterized protein
D SPHFLASMR4Y_00442 glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein K06996 K06996; uncharacterized protein
D SPHFLASMR4Y_00443 27 kDa antigen Cfp30B K06996 K06996; uncharacterized protein
D SPHFLASMR4Y_02529 glyoxalase K06996 K06996; uncharacterized protein
D SPHFLASMR4Y_02093 pyridoxamine 5'-phosphate oxidase K07006 K07006; uncharacterized protein
D SPHFLASMR4Y_00961 X-Pro dipeptidyl-peptidase (S15 family) K07018 K07018; uncharacterized protein
D SPHFLASMR4Y_02043 putative metal-dependent hydrolase K07044 K07044; uncharacterized protein
D SPHFLASMR4Y_02051 putative metal-dependent hydrolase K07044 K07044; uncharacterized protein
D SPHFLASMR4Y_00618 putative neutral zinc metallopeptidase K07054 K07054; uncharacterized protein
D SPHFLASMR4Y_00426 DNA-binding protein K07068 K07068; uncharacterized protein
D SPHFLASMR4Y_01937 DNA-binding protein K07068 K07068; uncharacterized protein
D SPHFLASMR4Y_01056 sulfite exporter TauE/SafE K07090 K07090; uncharacterized protein
D SPHFLASMR4Y_03152 membrane protein K07090 K07090; uncharacterized protein
D SPHFLASMR4Y_03181 sulfite exporter TauE/SafE K07090 K07090; uncharacterized protein
D SPHFLASMR4Y_03220 twin-arginine translocation pathway signal protein K07093 K07093; uncharacterized protein
D SPHFLASMR4Y_02159 putative inner membrane protein K07112 K07112; uncharacterized protein
D SPHFLASMR4Y_02160 membrane protein K07112 K07112; uncharacterized protein
D SPHFLASMR4Y_01807 hcpC; putative beta-lactamase HcpC K07126 K07126; uncharacterized protein
D SPHFLASMR4Y_02249 Sel1 repeat protein K07126 K07126; uncharacterized protein
D SPHFLASMR4Y_00884 esiB; secretory immunoglobulin A-binding protein EsiB K07126 K07126; uncharacterized protein
D SPHFLASMR4Y_00908 esiB; secretory immunoglobulin A-binding protein EsiB K07126 K07126; uncharacterized protein
D SPHFLASMR4Y_00359 ATPase K07133 K07133; uncharacterized protein
D SPHFLASMR4Y_02168 MAPEG family protein K07136 K07136; uncharacterized protein
D SPHFLASMR4Y_02781 MAPEG family protein K07136 K07136; uncharacterized protein
D SPHFLASMR4Y_02737 yecN; inner membrane protein YecN K07136 K07136; uncharacterized protein
D SPHFLASMR4Y_01903 transport protein K07148 K07148; uncharacterized protein
D SPHFLASMR4Y_01562 lon2; lon protease 2 K07157 K07157; uncharacterized protein
D SPHFLASMR4Y_01982 putative ACR K09005 K09005; uncharacterized protein
D SPHFLASMR4Y_01036 Yqey-like protein K09117 K09117; uncharacterized protein
D SPHFLASMR4Y_01540 hypothetical protein K09131 K09131; uncharacterized protein
D SPHFLASMR4Y_02932 putative ACR K09137 K09137; uncharacterized protein
D SPHFLASMR4Y_02283 YcgN protein K09160 K09160; uncharacterized protein
D SPHFLASMR4Y_02523 bacterial PH domain protein K09167 K09167; uncharacterized protein
D SPHFLASMR4Y_03274 YqcI/YcgG family protein K09190 K09190; uncharacterized protein
D SPHFLASMR4Y_02572 hypothetical protein K09703 K09703; uncharacterized protein
D SPHFLASMR4Y_00495 cupin K09705 K09705; uncharacterized protein
D SPHFLASMR4Y_03263 YaiI/YqxD-like protein K09768 K09768; uncharacterized protein
D SPHFLASMR4Y_02145 YciI-like protein K09780 K09780; uncharacterized protein
D SPHFLASMR4Y_00819 yedI; inner membrane protein YedI K09781 K09781; uncharacterized protein
D SPHFLASMR4Y_01988 ybaN; inner membrane protein YbaN K09790 K09790; uncharacterized protein
D SPHFLASMR4Y_01563 hypothetical protein K09791 K09791; uncharacterized protein
D SPHFLASMR4Y_03205 SIMPL domain-containing protein K09797 K09797; uncharacterized protein
D SPHFLASMR4Y_01363 26 kDa periplasmic immunogenic protein K09807 K09807; uncharacterized protein
D SPHFLASMR4Y_01011 protein YaaA K09861 K09861; uncharacterized protein
D SPHFLASMR4Y_03094 zinc-binding protein K09862 K09862; uncharacterized protein
D SPHFLASMR4Y_02248 peptidogalycan biosysnthesis/recognition K09919 K09919; uncharacterized protein
D SPHFLASMR4Y_01520 winged helix DNA-binding domain protein K09927 K09927; uncharacterized protein
D SPHFLASMR4Y_01312 ATP-binding protein K09928 K09928; uncharacterized protein
D SPHFLASMR4Y_02180 hypothetical protein K09930 K09930; uncharacterized protein
D SPHFLASMR4Y_00058 hypothetical protein K09946 K09946; uncharacterized protein
D SPHFLASMR4Y_02218 hypothetical protein K09948 K09948; uncharacterized protein
D SPHFLASMR4Y_02095 50S ribosomal protein L21 K09958 K09958; uncharacterized protein
D SPHFLASMR4Y_03275 aminomethyltransferase K09967 K09967; uncharacterized protein
D SPHFLASMR4Y_00934 TraB family protein K09973 K09973; uncharacterized protein
D SPHFLASMR4Y_00935 TraB family protein K09973 K09973; uncharacterized protein
D SPHFLASMR4Y_01195 hypothetical protein K09978 K09978; uncharacterized protein
D SPHFLASMR4Y_00032 hypothetical protein K09983 K09983; uncharacterized protein
D SPHFLASMR4Y_01591 hypothetical protein K09983 K09983; uncharacterized protein
D SPHFLASMR4Y_03085 stringent starvation protein B K09985 K09985; uncharacterized protein
D SPHFLASMR4Y_02849 proteophosphoglycan precursor K09986 K09986; uncharacterized protein
D SPHFLASMR4Y_00453 cytoplasmic protein K09987 K09987; uncharacterized protein
D SPHFLASMR4Y_01042 VWA domain containing CoxE-like protein K09989 K09989; uncharacterized protein
D SPHFLASMR4Y_03159 hypothetical protein K09991 K09991; uncharacterized protein
D SPHFLASMR4Y_01951 trehalose utilization K09992 K09992; uncharacterized protein
D SPHFLASMR4Y_02551 trehalose utilization K09992 K09992; uncharacterized protein
D SPHFLASMR4Y_00587 nucleic-acid-binding protein K07742 ylxR; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 13, 2024