+F Chromosome and associated proteins KO
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Chromosome and Associated Proteins - Shigella flexneri 2457T (serotype 2a)
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AEukaryotic type
B Sister chromatid cohesion proteins
C Cohesin complex
C Adherin complex
C CTF18-RFC complex
C Fork protection complex
C Other sister chromatid cohesion factors
B Meiosis-specific proteins
C Cohesin complex and associated proteins
C Synaptonemal complex
C DSB formation-related proteins
C Others
B Nucleosome assembly factors
C Histones
C Histone chaperones
D Nucleoplasmins
D NAPs (Nucleosome assembly proteins)
D CAF-1
D FACT complex
D Other Histone chaperones and regulators
C HMG (high mobility group) proteins
B Histone modification proteins
C HATs (histone acetyltransferases)
C HAT complexes
D PCAF complex
D STAGA complex
D TFTC complex
D TIP60 complex
D HBO1 complex
D MOZ/MORF complex
D SAGA complex
D SLIK complex
D ADA-HAT complex
D HAT-A2 complex
D ATAC complex
D HATB complex
D NSL complex
D MSL complex
D NuA3 complex
D NuA4 complex
D SAS complex
C HDACs (histone deacetylases)
D Class I HDACs
D Class II HDACs
D SIRTs (sirtuins, class III HDACs)
D Class IV HDACs
C HDAC complexes
D Sin3A-HDAC complex
D BRAF-HDAC complex
D REST complex
D SHIP complex
D MiDAC complex
D SMART complex
D Other HDAC associated proteins
C HMTs (histone methyltransferases)
D HKMTs (histone lysine methyltransferases)
D PRMTs (protein arginine metyltransferases)
C HMT complexes
D COMPASS/SET1 complex
D COMPASS/SET1 complex (yeast)
D MLL-HCF complex
D MLL3/MLL4 complex
D Dot1-containing complex
D CHTOP-methylosome complex
C Histone demethylases
C Polycomb repressive complex (PRC) and associated proteins
D Canonical PRC1 (PRC1.2/1.4)
E PRC1.4 specific proteins
D Noncanonical PRC1 (PRC1.1)
D Noncanonical PRC1 (PRC1.3/1.5)
D Noncanonical PRC1 (PRC1.6)
D PRC2.1
D PRC2.2
D PR-DUB complex
D Other PRC associated proteins
C Sir proteins
C Other histone modification proteins
B Chromosome condensation proteins
C Condensin I
C Condensin II
C Other regulators of chromosome condensation
B Centromeric chromatin formation proteins
C Kinetochore proteins
D Centromere proteins
D CPC (chromosomal passenger complex)
D KMN network proteins
E MIS12 complex
E NDC80 complex
D Mis6 complex
D COMA complex
D NMS complex
E NDC80 complex
E MIND kinetochore complex
D MIS16-MIS18 complex
D DASH complex
D CBF3 complex
D Others
C SAC (spindle assembly checkpoint) factors
D Core SAC proteins
D Motor proteins
E RZZ complex
E Dynein complex
D Protein kinases
D Others
C Other centromeric chromatin formation proteins
D Shugoshin
D PP2A (protein phosphatase 2A)
B Heterochromatin formation proteins
C HP1 (heterochromatin protein 1)
C MBPs (metylated DNA binding proteins)
C Other heterochromatin formation proteins
D S2100 dcm; DNA cytosine methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Gene silencing
C RISC (RNA-induced silencing complex)
C piRNA pathway
C RNA interference (RNAi) pathway
D RITS (RNA-induced transcriptional silencing) complex
D RDRC (RNA-directed RNA polymerase complex)
D Other RNAi proteins
C microRNA pathway
D Microprocessor complex
E S2802 rnc; RNase III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D RISC loading complex
D Other miRNA pathway proteins
C Transposable elements
B Centrosome formation proteins
C Centriole proteins
C Pericentriolar materials (PCM)
D Centriolar satellite
D Other PCM proteins
C Cyclins
C Kinases and associated factors
D Kinase associated protein
C Microtubules and associated factors
D gamma-tubulin ring complex
D Other tubulins
D Dynactin complex
D BRISC complex
D Microtubule-associated proteins
C Augmin complex
C Centrosome duplication proteins
D Centriole replication proteins
D Regulators of centriole replication
D Other centrosome duplication proteins
C Nde1-Su48 complex
C LINC complex
C 3M complex
C Gypsy chromatin insulator complex
C Other centrosome associated proteins
C Spindle formation proteins
B Sister chromatid separation proteins
C Securin and associated proteins
C Separase
C APC/C complex
C Aurora kinases
D Regulators of Aurora kinases
C TACC proteins
C Polo kinases
C Early mitotic inhibitors
B Chromatin remodeling factors
C BAF complex
C PBAF complex
C GBAF(ncBAF) complex
C CHRAC complex
C RSF complex
C WICH complex
C B-WICH complex
C NORC complex
C BRF complex
C NuRD complex
C NuRF complex
C NuRF complex (fruit fly)
C CERF complex
C SRCAP complex
C INO80 complex
C INO80 complex (yeast)
C RSC complex
C SWI/SNF complex
C SWR1 complex
C ASTRA complex
C Other chromatin remodeling factors
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AProkaryotic type
B Nucleoid associated proteins
C HNS (histone-like nucleoid structuring protein)
D S1323 hns; DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator K03746 hns; DNA-binding protein H-NS
D S2883 stpA; DNA-binding protein; H-NS-like protein K11685 stpA; DNA-binding protein StpA
C HU (heat unstable protein)
D S3663 hupA; DNA-binding protein HU-alpha (HU-2) K05787 hupA; DNA-binding protein HU-alpha
D S0391 hupB; DNA-binding protein HU-beta, NS1 (HU-1) K03530 hupB; DNA-binding protein HU-beta
C IHF (integration host factor)
D S1636 himA; integration host factor (IHF), alpha subunit K04764 ihfA; integration host factor subunit alpha
D S0972 himD; integration host factor (IHF), beta subunit K05788 ihfB; integration host factor subunit beta
C Other nucleoid associated proteins
D S1073 cbpA; curved DNA-binding protein K05516 cbpA; curved DNA-binding protein
D S1072 yccD; hypothetical protein K18997 cbpM; chaperone modulatory protein CbpM
D S4699 rob; right origin-binding protein K05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator
D S4009 dnaA; replication initiation protein DnaA K02313 dnaA; chromosomal replication initiator protein
D S3407 yraO; hypothetical protein K12961 diaA; DnaA initiator-associating protein
D S1034 yccV; hypothetical protein K11940 hspQ; heat shock protein HspQ
D S0805 dps; global regulator protein Dps K04047 dps; starvation-inducible DNA-binding protein
D S3516 fis; site-specific DNA inversion stimulation factor; DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D S4595 hfq; host factor I for bacteriophage Q beta replication K03666 hfq; host factor-I protein
D S3101 iciA; replication initiation inhibitor K05596 argP; LysR family transcriptional regulator, arginine and lysine transport system/DNA replication regulator
D S0889 lrp; regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D S2402 yejK; hypothetical protein K06899 ndpA; nucleoid-associated protein
B Chromosome partitioning proteins
C MukBEF complex
D S0984 mukB; kinesin-like cell division protein K03632 mukB; chromosome partition protein MukB
D S0983 mukE; hypothetical protein K03804 mukE; chromosome partition protein MukE
D S0982 mukF; mukF protein (killing factor KICB) K03633 mukF; chromosome partition protein MukF
C Condensin-like complex
C Divisome proteins
D S0093 ftsA; ATP-binding cell division protein K03590 ftsA; cell division protein FtsA
D S2964 hypothetical protein K05589 ftsB; cell division protein FtsB
D S4282 ftsE; ATP-binding component of a membrane-associated complex involved in cell division K09812 ftsE; cell division transport system ATP-binding protein
D S0083 ftsI; penicillin-binding protein 3; peptidoglycan synthetase K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]
D S0890 ftsK; cell division protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D S0082 ftsL; cell division protein; in growth of wall at septum K03586 ftsL; cell division protein FtsL
D S3736 ftsN; essential cell division protein K03591 ftsN; cell division protein FtsN
D S0092 ftsQ; cell division protein K03589 ftsQ; cell division protein FtsQ
D S0088 ftsW; membrane protein K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D S4283 ftsX; cell division membrane protein K09811 ftsX; cell division transport system permease protein
D S0094 ftsZ; tubulin-like GTP-binding protein and GTPase K03531 ftsZ; cell division protein FtsZ
D S2613 zipA; cell division protein involved in FtsZ ring K03528 zipA; cell division protein ZipA
D S3095 ygfE; hypothetical protein K09888 zapA; cell division protein ZapA
D S3741 yiiU; hypothetical protein K09892 zapB; cell division protein ZapB
D S1012 ycbW; hypothetical protein K18657 zapC; cell division protein ZapC
D S0101 yacF; hypothetical protein K18778 zapD; cell division protein ZapD
D S3487 yhcM; hypothetical protein K06916 zapE; cell division protein ZapE
D S4545 ytfB; hypothetical protein K07269 ytfB; cell division protein YtfB
D S2636 amiA; N-acetylmuramoyl-l-alanine amidase I K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D S3025 putative amidase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D S4592 amiB; N-acetylmuramoyl-l-alanine amidase II, murein hydrolase K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]
D S0415 acrA; acriflavin resistance protein AcrA precursor K03585 acrA; membrane fusion protein, multidrug efflux system
C Inhibitors of FtsZ assembly
D S1249 minC; cell division inhibitor K03610 minC; septum site-determining protein MinC
D S1248 minD; cell division inhibitor K03609 minD; septum site-determining protein MinD
D S1247 minE; cell division topological specificity factor K03608 minE; cell division topological specificity factor
D S1024 sulA; inhibitor of cell division and ftsZ ring formation K13053 sulA; cell division inhibitor SulA
D S4088 ttk; putative transcriptional regulator K05501 slmA; TetR/AcrR family transcriptional regulator
C Other chromosome partitioning proteins
D S0617 seqA; negative modulator of initiation of replication K03645 seqA; negative modulator of initiation of replication
D S3506 mreB; regulator of ftsI, penicillin binding protein 3 K03569 mreB; rod shape-determining protein MreB and related proteins
D S3505 mreC; rod shape-determining protein K03570 mreC; rod shape-determining protein MreC
D S3504 mreD; rod shape-determining protein K03571 mreD; rod shape-determining protein MreD
D S0669 mrdB; rod shape-determining membrane protein K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]
D S3267 parC; DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D S3275 parE; DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D S3947 gidA; glucose-inhibited division protein GidA K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D S3948 gidB; glucose-inhibited division protein GidB K03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]
D S3867 xerC; site-specific recombinase K03733 xerC; integrase/recombinase XerC
D S3079 xerD; site-specific recombinase K04763 xerD; integrase/recombinase XerD
D S2302 mrp; putative ATPase K03593 mrp; ATP-binding protein involved in chromosome partitioning
D S4383 fic; protein induced in stationary phase K04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]
D S3811 yihA; hypothetical protein K03978 engB; GTP-binding protein
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 24, 2025