+F Repair protein KO
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DNA Repair and Recombination Proteins - Saprospira grandis
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SGRA_3532 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SGRA_0784 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SGRA_2178 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SGRA_0787 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SGRA_3255 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGRA_1915 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGRA_3840 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SGRA_3532 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SGRA_0784 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SGRA_2178 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SGRA_0787 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SGRA_2573 xthA; exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SGRA_0313 nfi; endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E SGRA_1416 recJ; single-strand DNA specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SGRA_3356 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SGRA_3534 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SGRA_2140 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E SGRA_2411 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E SGRA_1752 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
E SGRA_1338 uvrC; uvrabc system protein c K03703 uvrC; excinuclease ABC subunit C
E SGRA_1994 uvrD; DNA-dependent ATPase I and helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGRA_4197 uvrD; ATP-dependent DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGRA_3534 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SGRA_3356 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SGRA_2310 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SGRA_2312 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SGRA_1819 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SGRA_1667 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SGRA_2123 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E SGRA_2592 mutS2; MutS2 family protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E SGRA_2905 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E SGRA_3760 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SGRA_0949 exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SGRA_3420 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SGRA_1874 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SGRA_3263 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SGRA_2081 holB; DNA polymerase III gamma/tau subunits-like protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SGRA_0076 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SGRA_1634 dnaQ; putative DNA polymerase III epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SGRA_3455 exonuclease RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SGRA_1265 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SGRA_3356 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SGRA_1994 uvrD; DNA-dependent ATPase I and helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGRA_4197 uvrD; ATP-dependent DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGRA_2177 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SGRA_3703 recD; putative exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SGRA_2017 recA; recA protein K03553 recA; recombination protein RecA
E SGRA_2671 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SGRA_2570 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SGRA_1974 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SGRA_0749 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SGRA_0397 sbcC; SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E SGRA_3243 sbcD; nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SGRA_2017 recA; recA protein K03553 recA; recombination protein RecA
E SGRA_3546 sms; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E SGRA_0442 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E SGRA_2098 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SGRA_1935 LexA DNA-binding protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SGRA_1416 recJ; single-strand DNA specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SGRA_1123 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E SGRA_3147 recR; recombination protein RecR K06187 recR; recombination protein RecR
E SGRA_1630 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E SGRA_2671 ruvA; holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SGRA_2570 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SGRA_1974 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E SGRA_3230 recB; UvrD/REP helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E SGRA_0277 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E SGRA_0397 sbcC; SMC domain protein K03546 sbcC; DNA repair protein SbcC/Rad50
E SGRA_3243 sbcD; nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SGRA_0537 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SGRA_3248 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SGRA_0854 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SGRA_2568 hupB; histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F SGRA_1282 hupB; DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SGRA_1416 recJ; single-strand DNA specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SGRA_1123 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F SGRA_3147 recR; recombination protein RecR K06187 recR; recombination protein RecR
F SGRA_3356 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F SGRA_0992 recQ; ATP-dependent DNA helicase, RecQ family protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SGRA_1574 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SGRA_3632 recQ; ATP-dependent DNA helicase, RecQ family protein K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SGRA_2140 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F SGRA_2411 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F SGRA_1752 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D SGRA_2017 recA; recA protein K03553 recA; recombination protein RecA
D SGRA_1630 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D SGRA_2177 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D SGRA_2224 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D SGRA_0617 dpx; PHP domain protein K02347 polX; DNA polymerase (family X)
C DNA helicases
C Modulation of nucleotide pools
D SGRA_3255 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGRA_1915 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGRA_3840 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SGRA_0943 nrdA; ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SGRA_0944 nrdB; ribonucleoside-diphosphate reductase small chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D SGRA_1478 phosphoesterase RecJ domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024