+F Repair protein KO
#
DNA Repair and Recombination Proteins - Streptomyces griseus
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SGR_1200 putative methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SGR_2910 putative methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SGR_5555 putative methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SGR_5882 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SGR_6501 putative uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SGR_6219 putative uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SGR_5705 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SGR_4126 putative adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SGR_3332 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E SGR_3186 putative ATP-dependent DNA helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SGR_5732 putative DNA hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_1957 putative phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_1704 putative DNA hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_3934 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_2455 putative MutT-family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_1664 putative deoxyuridine 5'-triphosphate pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SGR_1200 putative methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SGR_2910 putative methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SGR_5555 putative methylated-DNA--protein-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SGR_5882 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SGR_1596 conserved hypothetical protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D SGR_2911 putative DNA repair protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E SGR_6501 putative uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SGR_6219 putative uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SGR_6271 putative G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E SGR_1201 putative ADA-like transcriptional regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SGR_1368 putative ADA-like transcriptional regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SGR_5705 putative 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SGR_4126 putative adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SGR_2382 putative DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SGR_1907 putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SGR_724 putative formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SGR_1761 putative endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E SGR_4916 putative DNA repair hydrolase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E SGR_3332 putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SGR_1255 putative exonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SGR_4310 putative exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SGR_5390 putative endonuclease K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E SGR_998 putative endonuclease K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
E SGR_1137 putative NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SGR_2021 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SGR_5527 putative DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SGR_5564 putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E SGR_704 putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E SGR_5558 putative excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E SGR_5569 putative excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E SGR_2733 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGR_2337 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGR_2341 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGR_5527 putative DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SGR_1137 putative NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SGR_2021 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SGR_2869 rpoB; RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SGR_2868 rpoC; RNA polymerase beta prime subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SGR_2807 rpoA; RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SGR_6056 putative RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SGR_4422 putative transcriptional-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E SGR_2474 putative exoribonuclease large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SGR_2475 putative exoribonuclease small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SGR_5440 putative DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SGR_3701 dnaN; putative DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SGR_3397 dnaN2; putative DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SGR_4982 putative DNA-binding protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SGR_3299 putative DNA polymerase III K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SGR_1422 dnaQ2; putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SGR_5666 putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SGR_6000 dnaQ; putative DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SGR_3858 putative DNA polymerase III gamma subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SGR_1137 putative NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E SGR_2021 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SGR_2733 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGR_2337 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGR_2341 putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SGR_4851 putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SGR_3673 putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SGR_4677 putative DNA mismatch endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SGR_4825 putative exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SGR_1745 recA; putative RecA protein K03553 recA; recombination protein RecA
E SGR_6016 putative Holliday junction DNA helicase subunit B K03550 ruvA; holliday junction DNA helicase RuvA
E SGR_6017 putative Holliday junction DNA helicase subunit A K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SGR_6015 putative Holliday junction nuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SGR_6059 putative primosomal protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SGR_6250 putative exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E SGR_6249 putative exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SGR_1745 recA; putative RecA protein K03553 recA; recombination protein RecA
E SGR_4129 putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E SGR_3703 recF; putative DNA recombination and repair protein K03629 recF; DNA replication and repair protein RecF
E SGR_1914 putative ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SGR_5014 putative DNA recombination and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E SGR_3377 putative recombination and repair protein K06187 recR; recombination protein RecR
E SGR_5715 putative recombination and DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E SGR_6016 putative Holliday junction DNA helicase subunit B K03550 ruvA; holliday junction DNA helicase RuvA
E SGR_6017 putative Holliday junction DNA helicase subunit A K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SGR_6015 putative Holliday junction nuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E SGR_3547 putative CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E SGR_6250 putative exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E SGR_6249 putative exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E SGR_2195 putative Ku70/Ku80 protein K10979 ku; DNA end-binding protein Ku
E SGR_6689 putative Ku70/Ku80 protein K10979 ku; DNA end-binding protein Ku
E SGR_6690 putative ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E SGR_2196 conserved hypothetical protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SGR_3706 gyrA; putative DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SGR_1689 parC; putative A subunit of topoisomerase IV K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SGR_3705 gyrB; putative DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SGR_908 putative DNA gyrase B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SGR_1698 parE; putative B subunit of topoisomerase IV K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SGR_3301 putative DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SGR_4582 putative DNA-binding protein Hu 1 K03530 hupB; DNA-binding protein HU-beta
F SGR_1926 putative histone-like DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SGR_5014 putative DNA recombination and repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F SGR_3377 putative recombination and repair protein K06187 recR; recombination protein RecR
F SGR_1137 putative NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F SGR_2021 putative DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F SGR_2970 putative ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SGR_1706 putative ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SGR_5564 putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F SGR_704 putative excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F SGR_5558 putative excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SGR_6149 putative DNA damage inducible protein K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D SGR_1745 recA; putative RecA protein K03553 recA; recombination protein RecA
D SGR_1717 lexA; putative SOS regulatory protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D SGR_5715 putative recombination and DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SGR_6691 putative DNA polymerase III alpha subunit K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D SGR_4851 putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SGR_3673 putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SGR_1744 putative regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SGR_1718 putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D SGR_1611 putative ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D SGR_1760 putative ATP-dependent DNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D SGR_5732 putative DNA hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_1957 putative phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_1704 putative DNA hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_3934 conserved hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_2455 putative MutT-family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SGR_5722 putative ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D SGR_1664 putative deoxyuridine 5'-triphosphate pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SGR_1715 putative vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SGR_2299 putative ribonucleoside-diphosphate reductase large subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SGR_2300 putative ribonucleoside-diphosphate reductase small subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024