+F Repair protein KO
#
DNA Repair and Recombination Proteins - Streptomyces griseochromogenes
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AVL59_12620 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_17525 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_36715 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_13805 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_27580 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E AVL59_30180 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AVL59_33090 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AVL59_35725 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E AVL59_03000 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E AVL59_02320 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E AVL59_44790 helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D AVL59_45580 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_06175 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_24990 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_10280 DNA hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_35570 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_40755 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_41030 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_10520 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AVL59_12620 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_17525 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_36715 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_13805 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AVL59_27580 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D AVL59_29810 DNA repair protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E AVL59_30180 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AVL59_33090 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AVL59_36835 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E AVL59_12615 AraC family transcriptional regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E AVL59_13800 DNA-3-methyladenine glycosylase K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E AVL59_35725 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E AVL59_03000 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E AVL59_06435 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E AVL59_16195 DNA lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E AVL59_08990 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E AVL59_40595 DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E AVL59_09850 DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E AVL59_02320 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E AVL59_43710 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E AVL59_13535 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E AVL59_37570 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E AVL59_14965 endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
E AVL59_19720 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E AVL59_08490 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E AVL59_36925 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E AVL59_36640 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E AVL59_16310 ABC transporter K03701 uvrA; excinuclease ABC subunit A
E AVL59_36700 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
E AVL59_36615 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E AVL59_06660 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AVL59_06680 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AVL59_04740 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AVL59_36925 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E AVL59_19720 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E AVL59_08490 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F AVL59_04095 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F AVL59_04100 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F AVL59_24475 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F AVL59_04345 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F AVL59_46675 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F AVL59_33855 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F AVL59_43350 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E AVL59_06100 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E AVL59_06095 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E AVL59_37320 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E AVL59_00010 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E AVL59_40120 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E AVL59_02480 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E AVL59_34160 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AVL59_35945 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AVL59_12040 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AVL59_46385 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E AVL59_19720 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E AVL59_08490 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E AVL59_06660 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AVL59_06680 ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AVL59_04740 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AVL59_41100 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E AVL59_47115 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E AVL59_41350 helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E AVL59_09885 recombinase RecA K03553 recA; recombination protein RecA
E AVL59_34085 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AVL59_34080 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AVL59_34090 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E AVL59_33835 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E AVL59_25250 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E AVL59_32790 exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E AVL59_25255 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E AVL59_32795 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E AVL59_09885 recombinase RecA K03553 recA; recombination protein RecA
E AVL59_03020 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E AVL59_00020 DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF
E AVL59_08955 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E AVL59_39735 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E AVL59_02045 recombination protein RecR K06187 recR; recombination protein RecR
E AVL59_35645 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E AVL59_34085 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AVL59_34080 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AVL59_34090 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E AVL59_25250 exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E AVL59_32790 exonuclease K03546 sbcC; DNA repair protein SbcC/Rad50
E AVL59_25255 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E AVL59_32795 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E AVL59_46505 ATPase K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E AVL59_07260 Ku protein K10979 ku; DNA end-binding protein Ku
E AVL59_27035 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E AVL59_07255 ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F AVL59_00035 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F AVL59_10390 DNA topoisomerase IV K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F AVL59_00030 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F AVL59_10310 DNA topoisomerase IV subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F AVL59_02470 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F AVL59_08885 DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F AVL59_42485 integration host factor K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F AVL59_39735 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F AVL59_02045 recombination protein RecR K06187 recR; recombination protein RecR
F AVL59_19720 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F AVL59_08490 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F AVL59_03730 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F AVL59_10265 recombinase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F AVL59_32155 DEAD/DEAH box helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F AVL59_36640 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F AVL59_16310 ABC transporter K03701 uvrA; excinuclease ABC subunit A
F AVL59_36700 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D AVL59_33290 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D AVL59_09885 recombinase RecA K03553 recA; recombination protein RecA
D AVL59_10205 repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D AVL59_35645 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D AVL59_35445 DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D AVL59_41100 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D AVL59_47115 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D AVL59_09890 recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D AVL59_35070 phosphoesterase K02347 polX; DNA polymerase (family X)
C DNA helicases
D AVL59_10200 ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D AVL59_09855 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D AVL59_32175 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D AVL59_45580 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_06175 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_24990 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_10280 DNA hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_35570 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_40755 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_41030 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AVL59_35610 ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D AVL59_10520 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D AVL59_06880 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AVL59_10215 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AVL59_06875 ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024