+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Shewanella sp. LZH-2
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C JM642_05315 lspA; (GenBank) signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C JM642_18540 prepilin peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
C JM642_11150 HyaD/HybD family hydrogenase maturation endopeptidase K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C JM642_06335 guaA; (GenBank) glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C JM642_14910 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
C JM642_00265 C40 family peptidase K13695 nlpC; probable lipoprotein NlpC
B Family C44
C JM642_07415 purF; (GenBank) amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C JM642_14675 gltB; (GenBank) glutamate synthase large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C JM642_05425 SIS domain-containing protein K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C JM642_20160 glmS; (GenBank) glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C JM642_08375 asnB; (GenBank) asparagine synthase B K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C JM642_14415 DJ-1/PfpI family protein K05520 yhbO; deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
C JM642_09080 class GN sortase K07284 srtA; sortase A [EC:3.4.22.70]
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
C JM642_04520 L,D-transpeptidase family protein K19235 ybiS; L,D-transpeptidase YbiS
C JM642_11090 L,D-transpeptidase family protein K21470 ycbB; L,D-transpeptidase YcbB
C JM642_12150 L,D-transpeptidase family protein K21470 ycbB; L,D-transpeptidase YcbB
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
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AMetallo peptidases
B Family M1
C JM642_11710 M1 family metallopeptidase K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C JM642_13695 M1 family metallopeptidase K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C JM642_04760 pepN; (GenBank) aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
C JM642_08930 pepN; (GenBank) aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
C JM642_10805 M2 family metallopeptidase K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
B Family M3
C JM642_19765 prlC; (GenBank) oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70]
C JM642_05170 M3 family metallopeptidase K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
C JM642_06980 M3 family metallopeptidase K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
C JM642_11920 M3 family metallopeptidase K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
C JM642_00565 immune inhibitor A K09607 ina; immune inhibitor A [EC:3.4.24.-]
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
C JM642_17495 M9 family metallopeptidase K01387 colA; microbial collagenase [EC:3.4.24.3]
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
C JM642_04080 peptidase M13 K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C JM642_18160 M13 family metallopeptidase K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C JM642_18470 M13 family peptidase K07386 pepO; putative endopeptidase [EC:3.4.24.-]
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
B Family M16: pitrilysin family
C JM642_03165 insulinase family protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C JM642_05190 insulinase family protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C JM642_19165 insulinase family protein K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C JM642_14465 pepA; (GenBank) leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C JM642_15600 leucyl aminopeptidase family protein K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C JM642_16235 leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C JM642_16690 pepB; (GenBank) aminopeptidase PepB K07751 pepB; PepB aminopeptidase [EC:3.4.11.23]
B Family M18
B Family M19: membrane dipeptidase family
B Family M20
C JM642_10690 dapE; (GenBank) succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C JM642_11915 dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
C JM642_15605 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
B Family M23
C JM642_01625 M23 family metallopeptidase K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]
C JM642_08065 peptidoglycan DD-metalloendopeptidase family protein K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]
B Family M24
C JM642_13395 map; (GenBank) type I methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C JM642_00075 pepQ; (GenBank) Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C JM642_14380 aminopeptidase P family protein K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
C JM642_14430 carboxypeptidase M32 K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C JM642_15215 ftsH; (GenBank) ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C JM642_08575 htpX; (GenBank) protease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C JM642_07905 M48 family metallopeptidase K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C JM642_13355 rseP; (GenBank) sigma E protease regulator RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
C JM642_18425 hypothetical protein K21429 impA; immunomodulating metalloprotease
B Family M90
C JM642_06185 zinc-dependent peptidase K09933 mtfA; MtfA peptidase
B Family M98
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C JM642_03740 DegQ family serine endoprotease K04772 degQ; serine protease DegQ [EC:3.4.21.-]
C JM642_03735 degS; (GenBank) outer membrane-stress sensor serine endopeptidase DegS K04691 hhoB; serine protease DegS [EC:3.4.21.-]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C JM642_07220 S8 family serine peptidase K14645 K14645; serine protease [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C JM642_08430 S9 family peptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C JM642_09315 S9 family peptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C JM642_03550 S9 family peptidase K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
C JM642_00620 S9 family peptidase K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C JM642_15405 serine hydrolase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C JM642_16125 pbpG; (GenBank) D-alanyl-D-alanine endopeptidase K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
C JM642_10360 dacB; (GenBank) D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C JM642_12660 clpP; (GenBank) ATP-dependent Clp endopeptidase proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C JM642_11325 brxL; (GenBank) protease Lon-related BREX system protein BrxL K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C JM642_12650 lon; (GenBank) endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C JM642_19430 lexA; (GenBank) repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
C JM642_10670 umuD; (GenBank) translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C JM642_11315 S24 family peptidase K03503 umuD; DNA polymerase V [EC:3.4.21.-]
B Family S26: signal peptidase I family
C JM642_14570 lepB; (GenBank) signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C JM642_01700 alpha/beta fold hydrolase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
B Family S41: C-terminal processing peptidase family
C JM642_00215 S41 family peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C JM642_08925 prc; (GenBank) carboxy terminal-processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C JM642_05840 PDZ domain-containing protein K08676 tri; tricorn protease [EC:3.4.21.-]
B Family S45
B Family S49: protease IV family
C JM642_10480 sppA; (GenBank) signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
C JM642_07630 sohB; (GenBank) protease SohB K04774 sohB; serine protease SohB [EC:3.4.21.-]
B Family S50
B Family S51
C JM642_08570 pepE; (GenBank) dipeptidase PepE K05995 pepE; dipeptidase E [EC:3.4.13.21]
B Family S53
B Family S54: Rhomboid family
C JM642_20060 glpG; (GenBank) rhomboid family intramembrane serine protease GlpG K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]
C JM642_10865 rrtA; (GenBank) rhombosortase K28165 rrtA; rhombosortase
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C JM642_02640 hslV; (GenBank) ATP-dependent protease subunit HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C JM642_11060 isoaspartyl peptidase/L-asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
B Family T3: gamma-glutamyltransferase family
C JM642_11890 ggt; (GenBank) gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C JM642_17160 ggt; (GenBank) gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
C JM642_14965 yegQ; (GenBank) tRNA 5-hydroxyuridine modification protein YegQ K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C JM642_04310 U32 family peptidase K24847 rlhA; 23S rRNA 5-hydroxycytidine C2501 synthase
C JM642_14985 U32 family peptidase K24845 ubiV; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiV [EC:1.97.1.15]
C JM642_14980 U32 family peptidase K24844 ubiU; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiU [EC:1.97.1.15]
B Family U62
C JM642_02960 pmbA; (GenBank) metalloprotease PmbA K03592 pmbA; PmbA protein
C JM642_02920 tldD; (GenBank) metalloprotease TldD K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
C JM642_09860 eco; (GenBank) serine protease inhibitor ecotin K08276 eco; ecotin
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C JM642_17635 hflC; (GenBank) protease modulator HflC K04087 hflC; modulator of FtsH protease HflC
C JM642_17640 hflK; (GenBank) FtsH protease activity modulator HflK K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 18, 2025
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Classification taken and modified from MEROPS