+C Two-component system KO
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Two-Component System - Shewanella putrefaciens 200
%
!
AOmpR family
B PhoR-PhoB (phosphate starvation response)
C Sput200_1303 PAS/PAC sensor signal transduction histidine kinase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C Sput200_1302 two component transcriptional regulator, winged helix family K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
C Sput200_0109 integral membrane sensor signal transduction histidine kinase K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C Sput200_2279 two component sensor histidine kinase, PhoQ K07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]
C Sput200_0110 two component transcriptional regulator, winged helix family K07660 phoP; two-component system, OmpR family, response regulator PhoP
C Sput200_2278 two component transcriptional regulator, PhoP K07660 phoP; two-component system, OmpR family, response regulator PhoP
B EnvZ-OmpR (osmotic stress response)
C Sput200_0115 periplasmic sensor histidine kinase for osmolarity response, EnvZ K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C Sput200_0116 two component transcriptional regulator for porins, OmpR K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
B CpxA-CpxR (envelope stress response)
C Sput200_0224 periplasmic sensor histidine kinase, CpxA K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
C Sput200_0225 two component transcriptional regulator for periplasmic stress, CpxR K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
C Sput200_1928 integral membrane sensor signal transduction histidine kinase K07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]
C Sput200_1927 two component transcriptional regulator, winged helix family K07666 qseB; two-component system, OmpR family, response regulator QseB
B KdpD-KdpE (potassium transport)
C Sput200_3187 osmosensitive K+ channel signal transduction histidine kinase, KdpD K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C Sput200_3186 KDP operon signal transduction regulator, KdpE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
C Sput200_4214 two component response regulator for KtrAB potassium uptake, KtrE K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
C Sput200_0610 two component transcriptional regulator for aerobic respiration, ArcA K07773 arcA; two-component system, OmpR family, aerobic respiration control protein ArcA
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
C Sput200_4303 integral membrane sensor signal transduction histidine kinase K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
C Sput200_4302 two component transcriptional regulator, winged helix family K18144 adeR; two-component system, OmpR family, response regulator AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C Sput200_1008 integral membrane sensor signal transduction histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C Sput200_0256 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C Sput200_1764 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C Sput200_1009 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C Sput200_0581 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
C Sput200_0215 two component transcriptional regulator, winged helix family K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
C Sput200_0616 sensor histidine kinase for nitrate/nitrite response, NarQ K07674 narQ; two-component system, NarL family, nitrate/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]
C Sput200_0615 two component transcriptional regulator for nitrate/nitrite response, NarP K07685 narP; two-component system, NarL family, nitrate/nitrite response regulator NarP
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C Sput200_2905 hybrid periplasmic sensor histidine kinase, BarA K07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]
C Sput200_1658 two component transcriptional regulator, UvrY K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
C Sput200_4075 two component transcriptional regulator, LuxR family K07690 evgA; two-component system, NarL family, response regulator EvgA
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
C Sput200_0208 signal transduction histidine kinase regulating citrate/malate metabolism K02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C Sput200_1566 signal transduction histidine kinase, LytS K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C Sput200_1565 two component transcriptional regulator, LytTR family K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C Sput200_0230 sensor histidine kinase for nitrogen response, NtrB K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C Sput200_0229 two component, sigma54 specific, transcriptional regulator, Fis family K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C Sput200_2532 C4-dicarboxylate transport sensor protein, DctB K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C Sput200_2533 two component Sigma54 specific transcriptional regulator of C4-dicarboxylate transport, DctD K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C Sput200_0078 integral membrane sensor signal transduction histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
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ACheA family
B CheA-CheYBV (chemotaxis)
C Sput200_2721 CheA signal transduction histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C Sput200_2723 chemotaxis response regulator receiver, CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C Sput200_3451 response regulator receiver protein K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C Sput200_2720 response regulator receiver modulated CheB methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C Sput200_2345 chemotaxis response regulator, CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C Sput200_2517 response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C Sput200_2764 chemotaxis response regulator, CheV K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C Sput200_2936 response regulator receiver modulated CheW protein K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
C Sput200_0596 sensor histidine kinase for the tetrathionate reductase regulon, TtrS K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
C Sput200_0459 sensor histidine kinase for thiosulfate/tetrathionate response, TtrS K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
C Sput200_0597 two component response regulator for tetrathionate reductase regulon, TtrR K13041 ttrR; two-component system, LuxR family, response regulator TtrR
C Sput200_0457 two component transciptional regulator for thiosulfate/tetrathionate response, TtrR K13041 ttrR; two-component system, LuxR family, response regulator TtrR
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C Sput200_2744 sensor histidine kinase with PAS sensory domain for flagellar biosynthesis, FlrB K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C Sput200_2743 flagella biosynthesis regulator, FlrC K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C Sput200_0445 integral membrane sensor signal transduction histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C Sput200_0446 two component transcriptional regulator, Fis family K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C Sput200_3427 sensor histidine kinase for anaerobic respiratory control, ArcS K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023