+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Sarcophilus harrisii (Tasmanian devil)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 100914618 RNMT; mRNA cap guanine-N7 methyltransferase K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 100921795 RNGTT; mRNA-capping enzyme isoform X1 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 100930055 CDK7; cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 100932113 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X6 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 100914522 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 100927120 RAMAC; RNA guanine-N7 methyltransferase activating subunit isoform X2 K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 100934151 NCBP1; nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 100921959 nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 100923162 NCBP2; nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 100915903 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 100933435 CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 100919609 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X1 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 100931522 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 isoform X1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 100924558 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 100925407 CPSF1; cleavage and polyadenylation specificity factor subunit 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E 100923113 CPSF2; cleavage and polyadenylation specificity factor subunit 2 isoform X1 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 100927308 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 100922359 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 100928206 CPSF4L; LOW QUALITY PROTEIN: putative cleavage and polyadenylation specificity factor subunit 4-like protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 100930119 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 100914633 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 111719482 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 100930570 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 100915116 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 100920526 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 100930071 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 100935181 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 100926262 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 100918926 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 100930611 SYMPK; symplekin isoform X1 K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 100925653 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' isoform X1 K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 100924991 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 100930096 SNRPE; small nuclear ribonucleoprotein E K11097 SNRPE; small nuclear ribonucleoprotein E
E 116419220 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 100928509 SNRPG; small nuclear ribonucleoprotein G K11099 SNRPG; small nuclear ribonucleoprotein G
E 100928190 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 100931971 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 100923113 CPSF2; cleavage and polyadenylation specificity factor subunit 2 isoform X1 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 100927308 CPSF3; cleavage and polyadenylation specificity factor subunit 3 isoform X1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 100926262 CSTF2; cleavage stimulation factor subunit 2 isoform X1 K14407 CSTF2; cleavage stimulation factor subunit 2
E 100930611 SYMPK; symplekin isoform X1 K06100 SYMPK; symplekin
E 100934207 SLBP; histone RNA hairpin-binding protein isoform X2 K18710 SLBP; histone RNA hairpin-binding protein
E 111721096 LOW QUALITY PROTEIN: oocyte-specific histone RNA stem-loop-binding protein 2-like K18710 SLBP; histone RNA hairpin-binding protein
E 100923615 CASP8AP2; CASP8-associated protein 2 isoform X1 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 100914988 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 116422849 transcription elongation factor SPT4-A-like K15171 SUPT4H1; transcription elongation factor SPT4
E 100921154 SUPT5H; transcription elongation factor SPT5 isoform X1 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 100917802 METTL3; N6-adenosine-methyltransferase catalytic subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 100917530 METTL14; N6-adenosine-methyltransferase non-catalytic subunit isoform X1 K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 111719076 METTL4; N(6)-adenine-specific DNA methyltransferase METTL4 isoform X1 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 100929591 METTL16; RNA N6-adenosine-methyltransferase METTL16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 100922733 WTAP; pre-mRNA-splicing regulator WTAP K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 100924191 VIRMA; protein virilizer homolog isoform X1 K22910 VIRMA; protein virilizer
E 100914798 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 100931592 RBM15; RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E 100926040 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X4 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 100926768 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X1 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 100932572 PAPOLG; poly(A) polymerase gamma isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 100916855 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 100930839 TENT2; poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 100915540 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 100929064 BARD1; BRCA1-associated RING domain protein 1 isoform X1 K10683 BARD1; BRCA1-associated RING domain protein 1
E 100933137 RBM26; RNA-binding protein 26 isoform X1 K13192 RBM26; RNA-binding protein 26
E 100934225 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X1 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 100924890 ALKBH5; RNA demethylase ALKBH5 K10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 100925778 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 100913682 DHX40; probable ATP-dependent RNA helicase DHX40 isoform X1 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 100920484 KIN; DNA/RNA-binding protein KIN17 K13102 KIN; DNA/RNA-binding protein KIN17
D 100930691 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 100924027 METTL22; methyltransferase-like protein 22 isoform X1 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 100930973 TENT5A; terminal nucleotidyltransferase 5A K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 111720232 TENT5B; LOW QUALITY PROTEIN: terminal nucleotidyltransferase 5B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 100934447 TENT5C; terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 100915636 TENT5D; terminal nucleotidyltransferase 5D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 100934915 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X1 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 100924227 SRRT; serrate RNA effector molecule homolog isoform X1 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 100916037 RBM8A; RNA-binding protein 8A K12876 RBM8A; RNA-binding protein 8A
E 100920727 MAGOH; LOW QUALITY PROTEIN: protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 100925707 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 100924980 THO complex subunit 4-like K12881 THOC4; THO complex subunit 4
E 100921090 DDX39B; spliceosome RNA helicase DDX39B isoform X3 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 100914020 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 100932538 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 100918189 CCDC174; coiled-coil domain-containing protein 174 isoform X2 K25178 CCDC174; coiled-coil domain-containing protein 174
E 100924142 CASC3; protein CASC3 K14323 CASC3; protein CASC3
E 100919408 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 100919300 PNN; pinin K13114 PNN; pinin
E 100933439 ACIN1; LOW QUALITY PROTEIN: apoptotic chromatin condensation inducer in the nucleus K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 100919922 RNPS1; RNA-binding protein with serine-rich domain 1 isoform X1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 100914811 SRRM1; serine/arginine repetitive matrix protein 1 isoform X1 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 100914787 THOC1; THO complex subunit 1 isoform X2 K12878 THOC1; THO complex subunit 1
E 100927976 THOC2; THO complex subunit 2 isoform X1 K12879 THOC2; THO complex subunit 2
E 100932230 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 100925707 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 100924980 THO complex subunit 4-like K12881 THOC4; THO complex subunit 4
E 100913496 THOC5; THO complex subunit 5 homolog isoform X1 K13174 THOC5; THO complex subunit 5
E 100928782 THOC6; THO complex subunit 6 homolog isoform X1 K13175 THOC6; THO complex subunit 6
E 100927404 THOC7; THO complex subunit 7 homolog isoform X1 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 100915765 PCID2; PCI domain-containing protein 2 isoform X1 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 100919883 SEM1; 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 100926019 ENY2; transcription and mRNA export factor ENY2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 105751048 transcription and mRNA export factor ENY2-like K11368 ENY2; enhancer of yellow 2 transcription factor
E 100923233 centrin-1 K10840 CETN2; centrin-2
E 111721592 CETN2; centrin-2 isoform X1 K10840 CETN2; centrin-2
E 100931809 CETN3; centrin-3 K16466 CETN3; centrin-3
E 100934196 MCM3AP; germinal-center associated nuclear protein K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 100926491 TPR; nucleoprotein TPR isoform X1 K09291 TPR; nucleoprotein TPR
E 100915907 RAE1; mRNA export factor K14298 RAE1; mRNA export factor
E 100926116 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 100918043 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 100929584 NUP85; nuclear pore complex protein Nup85 isoform X1 K14304 NUP85; nuclear pore complex protein Nup85
E 100931505 NUP43; nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E 100923791 NUP50; nuclear pore complex protein Nup50 isoform X1 K14295 NUP50; nuclear pore complex protein Nup50
E 100922756 NUP54; nucleoporin p54 isoform X1 K14308 NUP54; nuclear pore complex protein Nup54
E 100932411 NUP62; nuclear pore glycoprotein p62 isoform X3 K14306 NUP62; nuclear pore complex protein Nup62
E 100920717 nuclear pore glycoprotein p62-like K14306 NUP62; nuclear pore complex protein Nup62
E 100923688 NUP88; nuclear pore complex protein Nup88 isoform X1 K14318 NUP88; nuclear pore complex protein Nup88
E 100916424 NUP93; nuclear pore complex protein Nup93 isoform X2 K14309 NUP93; nuclear pore complex protein Nup93
E 100931657 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X1 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 100921710 NUP107; nuclear pore complex protein Nup107 K14301 NUP107; nuclear pore complex protein Nup107
E 100931493 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 100925654 NUP188; nucleoporin NUP188 homolog isoform X2 K14311 NUP188; nuclear pore complex protein Nup188
E 100915566 NUP153; nuclear pore complex protein Nup153 K14296 NUP153; nuclear pore complex protein Nup153
E 100913918 NUP155; nuclear pore complex protein Nup155 isoform X2 K14312 NUP155; nuclear pore complex protein Nup155
E 100919357 NUP160; nuclear pore complex protein Nup160 K14303 NUP160; nuclear pore complex protein Nup160
E 100926992 NUP35; nucleoporin NUP35 isoform X1 K14313 NUP35; nuclear pore complex protein Nup53
E 100921974 NUP205; nuclear pore complex protein Nup205 isoform X2 K14310 NUP205; nuclear pore complex protein Nup205
E 100923610 NUP210L; nuclear pore membrane glycoprotein 210-like isoform X1 K14314 NUP210; nuclear pore complex protein Nup210
E 100930853 NUP210; nuclear pore membrane glycoprotein 210 K14314 NUP210; nuclear pore complex protein Nup210
E 100913204 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 100934794 nuclear envelope pore membrane protein POM 121C K14316 POM121; nuclear pore complex protein Nup121
E 100922457 NUP58; nucleoporin p58/p45 isoform X2 K14307 NUPL1; nucleoporin p58/p45
E 100929677 NUP42; nucleoporin NUP42 isoform X3 K14321 NUPL2; nucleoporin-like protein 2
E 100922833 NDC1; nucleoporin NDC1 isoform X1 K14315 NDC1; nucleoporin NDC1
E 100935281 SEH1L; nucleoporin SEH1 isoform X1 K14299 SEH1; nucleoporin SEH1
E 100934513 E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 100914061 SENP2; sentrin-specific protease 2 isoform X1 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 100921805 AAAS; aladin isoform X1 K14320 AAAS; aladin
E 100931809 CETN3; centrin-3 K16466 CETN3; centrin-3
E 100929024 GLE1; nucleoporin GLE1 K18723 GLE1; nucleoporin GLE1
E 100918153 NXF1; nuclear RNA export factor 1 isoform X1 K14284 NXF; nuclear RNA export factor
E 100914943 NTF2-related export protein 2 K14285 NXT1_2; NTF2-related export protein 1/2
E 100923209 NXT2; LOW QUALITY PROTEIN: NTF2-related export protein 2 K14285 NXT1_2; NTF2-related export protein 1/2
E 105749534 NTF2-related export protein 2 K14285 NXT1_2; NTF2-related export protein 1/2
D Ran-mediated transport factors
E 100916523 GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 100913923 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
E 100925555 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 100920101 acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 100933639 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 100916471 TNFSF13; tumor necrosis factor ligand superfamily member 13 K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13
E 100922443 ELAVL1; ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 100928199 ELAVL4; ELAV-like protein 4 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 100921667 ELAVL3; ELAV-like protein 3 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 100934042 mucin-5AC-like K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 100917566 ELAVL2; ELAV-like protein 2 isoform X4 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 100933964 FAF2; FAS-associated factor 2 isoform X4 K18726 FAF2; FAS-associated factor 2
E 100919484 VCP; transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 100933446 VCPKMT; protein-lysine methyltransferase METTL21D isoform X1 K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 100929125 TNPO2; transportin-2 isoform X1 K18727 TNPO2; transportin-2
E 100928934 XPO1; exportin-1 isoform X1 K14290 XPO1; exportin-1
E 100934660 XPO7; exportin-7 K18460 XPO7; exportin-7
E 100922598 RANBP17; ran-binding protein 17 isoform X1 K24115 RANBP17; Ran-binding protein 17
E 100918662 RANGAP1; ran GTPase-activating protein 1 isoform X2 K14319 RANGAP1; Ran GTPase-activating protein 1
E 100934890 TAF15; TATA-binding protein-associated factor 2N K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 100934653 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 100921545 EIF4E; eukaryotic translation initiation factor 4E isoform X4 K03259 EIF4E; translation initiation factor 4E
E 100928988 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 100921249 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 100916209 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 100927850 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100921634 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 100933156 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100922583 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 100914653 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 100918487 LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 111718631 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 100918495 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 100930495 EIF4ENIF1; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E transporter K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 100929581 ANGEL2; protein angel homolog 2 isoform X1 K18729 ANGEL; protein angel
E 100922255 ANGEL1; protein angel homolog 1 isoform X1 K18729 ANGEL; protein angel
E 100915688 FXR2; fragile X mental retardation syndrome-related protein 2 K15516 FMR; fragile X mental retardation protein
E 100913594 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 100929616 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 100913942 CYFIP1; cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 100928078 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 100926792 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 100914498 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 100934814 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100916666 CPEB2; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100920669 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100925745 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100933296 DDX3X; ATP-dependent RNA helicase DDX3X isoform X3 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 100917185 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 100917256 GIGYF1; GRB10-interacting GYF protein 1 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 100933306 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 100924794 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 100913560 polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 100917652 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 100915293 PABPC1L; polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 100926106 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 100926263 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 100930402 PAIP2B; LOW QUALITY PROTEIN: polyadenylate-binding protein-interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 100923697 SKIV2L; helicase SKI2W isoform X1 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 100918321 DEAF1; deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 100921277 MCTS1; malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E 105749439 DENR; density-regulated protein isoform X1 K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 100932638 APOBEC1; C->U-editing enzyme APOBEC-1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 100927966 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 100920403 PYM1; partner of Y14 and mago isoform X1 K14294 WIBG; partner of Y14 and mago
E 100919352 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 100918877 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 100921430 MSI2; RNA-binding protein Musashi homolog 2 isoform X3 K14411 MSI; RNA-binding protein Musashi
E 100920527 MSI1; RNA-binding protein Musashi homolog 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 100926193 DAZAP1; DAZ-associated protein 1 isoform X6 K14411 MSI; RNA-binding protein Musashi
E 100914313 HBS1L; HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 100929706 PELO; protein pelota homolog K06965 PELO; protein pelota
E 100934313 PABPN1L; embryonic polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 100913313 polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E 100934314 ATP-dependent RNA helicase DDX19B isoform X1 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 100934572 ATP-dependent RNA helicase DDX19B isoform X1 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 100923942 DDX25; ATP-dependent RNA helicase DDX25 isoform X3 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 100930593 XAB2; pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 100921716 SARNP; SAP domain-containing ribonucleoprotein isoform X1 K18732 SARNP; SAP domain-containing ribonucleoprotein
E 100934866 RCC1; regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 100930131 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 100927728 PURA; transcriptional activator protein Pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha
E 116421507 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 100925284 POLDIP3; polymerase delta-interacting protein 3 isoform X3 K22414 POLDIP3; polymerase delta-interacting protein 3
E 100929409 ZC3H11A; zinc finger CCCH domain-containing protein 11A isoform X1 K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 100926298 LENG8; leukocyte receptor cluster member 8 isoform X1 K23802 LENG8; SAC3 family protein LENG8/THP3
E 100930472 PATL2; protein PAT1 homolog 2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 100925220 ETF1; eukaryotic peptide chain release factor subunit 1 isoform X1 K03265 ETF1; peptide chain release factor subunit 1
E 100934762 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1 K03267 ERF3; peptide chain release factor subunit 3
E 100929203 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 100930896 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 100918373 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 100913987 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 100921980 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 100927043 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 100932648 serine/threonine-protein phosphatase 2A catalytic subunit beta isoform-like K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 100922551 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 100927161 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 100931978 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 100935274 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 100922930 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 100933266 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X3 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 100916681 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 100922455 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X3 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 100933047 PPP2R3B; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 100928637 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 100914332 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 100931239 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 100914865 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 100930217 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X7 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 100929642 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 100924141 SMG5; protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 100926541 protein SMG5-like K11125 SMG5; protein SMG5
E 100929081 SMG6; telomerase-binding protein EST1A isoform X2 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 100921787 SMG7; protein SMG7 isoform X4 K14409 SMG7; protein SMG7
E 100913947 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 100918802 SMG9; protein SMG9 K18735 SMG9; protein SMG9
E 100917185 GIGYF2; GRB10-interacting GYF protein 2 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 100917256 GIGYF1; GRB10-interacting GYF protein 1 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 100915484 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 100927721 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 100927598 DHX34; LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 100918915 GTPBP1; LOW QUALITY PROTEIN: GTP-binding protein 1 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 100925419 PUM3; pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 100920694 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 100913898 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
E 100914159 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 100920535 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 100921968 BICD1; protein bicaudal D homolog 1 isoform X1 K18739 BICD; protein bicaudal D
E 100924694 protein bicaudal D homolog 2 isoform X3 K18739 BICD; protein bicaudal D
E 100934217 EXD1; piRNA biogenesis protein EXD1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 100928302 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 100923807 actin, cytoplasmic type 5 K05692 ACTB_G1; actin beta/gamma 1
E 100919051 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 100916712 LOW QUALITY PROTEIN: actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 100925319 MBP; myelin basic protein isoform X1 K17269 MBP; myelin basic protein
E 100932975 VIM; vimentin K07606 VIM; vimentin
E 105751160 metallothionein-1D K14739 MT1_2; metallothionein 1/2
E 105751161 metallothionein-1E K14739 MT1_2; metallothionein 1/2
E 100920166 metallothionein-2B K14739 MT1_2; metallothionein 1/2
E 100921308 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 116420796 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 100916357 TBX6; T-box transcription factor TBX6 K10180 TBX6; T-box protein 6
E 105749208 NANOS1; LOW QUALITY PROTEIN: nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 100932584 KHSRP; far upstream element-binding protein 2 K13210 FUBP; far upstream element-binding protein
E 100918909 FUBP1; far upstream element-binding protein 1 isoform X1 K13210 FUBP; far upstream element-binding protein
E 100934657 FUBP3; far upstream element-binding protein 3 isoform X1 K13210 FUBP; far upstream element-binding protein
E 100927986 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 100919601 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 100915280 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 100924943 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 116423065 heterogeneous nuclear ribonucleoproteins A2/B1-like isoform X1 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 100918638 HAX1; HCLS1-associated protein X-1 isoform X1 K16220 HAX1; HCLS1-associated protein X-1
E 100916554 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 100923120 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X5 K17597 STAU; double-stranded RNA-binding protein Staufen
E 100930752 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 100927703 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X9 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 100934495 PTBP1; polypyrimidine tract-binding protein 1 isoform X1 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 100934814 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100916666 CPEB2; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100920669 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100925745 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 100915688 FXR2; fragile X mental retardation syndrome-related protein 2 K15516 FMR; fragile X mental retardation protein
E 100913594 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 100929616 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 100913942 CYFIP1; cytoplasmic FMR1-interacting protein 1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 100928078 CYFIP2; cytoplasmic FMR1-interacting protein 2 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 100913973 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 100921357 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 100934944 PCBP4; poly(rC)-binding protein 4 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 100920237 CAPRIN1; caprin-1 isoform X1 K18743 CAPRIN1; caprin-1
E 100932130 CAPRIN2; caprin-2 isoform X1 K18744 CAPRIN2; caprin-2
E 100933136 YBX1; Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 100934609 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 100920633 AGO1; protein argonaute-1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 100935023 AGO2; protein argonaute-2 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 100925600 AGO4; protein argonaute-4 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 100926128 AGO3; protein argonaute-3 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 100934653 EIF4E1B; eukaryotic translation initiation factor 4E type 1B K03259 EIF4E; translation initiation factor 4E
E 100921545 EIF4E; eukaryotic translation initiation factor 4E isoform X4 K03259 EIF4E; translation initiation factor 4E
E 100928988 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1 K03259 EIF4E; translation initiation factor 4E
E 100929203 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 100933296 DDX3X; ATP-dependent RNA helicase DDX3X isoform X3 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 100917240 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 100914440 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 100923312 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 100915282 MEX3B; RNA-binding protein MEX3B isoform X1 K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 100922825 MEX3A; LOW QUALITY PROTEIN: RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 100913203 LSM14A; protein LSM14 homolog A isoform X1 K18749 LSM14; protein LSM14
E 100925564 LSM14B; protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 100913973 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 100933136 YBX1; Y-box-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 100934392 WTIP; Wilms tumor protein 1-interacting protein K16682 AJUBA; LIM domain-containing protein
E 116421812 AJUBA; LIM domain-containing protein ajuba K16682 AJUBA; LIM domain-containing protein
E 100932638 APOBEC1; C->U-editing enzyme APOBEC-1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 100914817 single-stranded DNA cytosine deaminase K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 100922657 MOV10; helicase MOV-10 isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 100933819 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 116421266 proline-rich nuclear receptor coactivator 2-like K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 116422527 proline-rich nuclear receptor coactivator 2-like K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 100918257 TNPO1; transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 100929642 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 100924141 SMG5; protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 100926541 protein SMG5-like K11125 SMG5; protein SMG5
E 100929081 SMG6; telomerase-binding protein EST1A isoform X2 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 100921787 SMG7; protein SMG7 isoform X4 K14409 SMG7; protein SMG7
E 100920632 ZFP36; mRNA decay activator protein ZFP36 K15308 TTP; tristetraprolin
E 100927385 ZFP36L2; mRNA decay activator protein ZFP36L2 isoform X1 K18753 ZFP36L; butyrate response factor
E 100924699 ZFP36L1; mRNA decay activator protein ZFP36L1 isoform X4 K18753 ZFP36L; butyrate response factor
E 100922372 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 100933412 LIN28B; protein lin-28 homolog B K18754 LIN28; protein lin-28
E 100930812 HTT; huntingtin isoform X1 K04533 HD; huntingtin
E 100918406 IPO8; importin-8 isoform X1 K18755 IPO8; importin-8
E 100930814 BICC1; protein bicaudal C homolog 1 isoform X1 K18756 BICC1; protein bicaudal C
E 100919352 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 100918877 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 100929360 cAMP-dependent protein kinase catalytic subunit alpha K04345 PKA; protein kinase A [EC:2.7.11.11]
E 100915481 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha K04345 PKA; protein kinase A [EC:2.7.11.11]
E 100934183 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X2 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 100913731 cAMP-dependent protein kinase catalytic subunit alpha-like K04345 PKA; protein kinase A [EC:2.7.11.11]
E 100930726 LARP1B; la-related protein 1B isoform X1 K18757 LARP1; la-related protein 1
E 100925744 LARP1; la-related protein 1 isoform X1 K18757 LARP1; la-related protein 1
E 100918446 ATXN2L; ataxin-2-like protein isoform X2 K23625 ATXN2_2L; ataxin 2/2L
E 100919478 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 100922624 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 100920013 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 100926238 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 100913641 LSM1; U6 snRNA-associated Sm-like protein LSm1 isoform X1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 100929839 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 100924692 LOW QUALITY PROTEIN: U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 100918710 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 100928431 LSM4; U6 snRNA-associated Sm-like protein LSm4 isoform X1 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 100917493 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 100918491 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 100923315 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 100917785 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 100929070 KLC3; kinesin light chain 3 isoform X1 K10407 KLC; kinesin light chain
E 100924072 KLC2; kinesin light chain 2 K10407 KLC; kinesin light chain
E 100924347 KLC1; kinesin light chain 1 isoform X1 K10407 KLC; kinesin light chain
E 100925884 KLC4; kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 100920694 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 100913898 MYO5C; unconventional myosin-Vc isoform X1 K10357 MYO5; myosin V
E 100914159 MYO5A; unconventional myosin-Va isoform X1 K10357 MYO5; myosin V
E 100932522 tubulin alpha-1D chain isoform X2 K07374 TUBA; tubulin alpha
E 100932786 tubulin alpha-4A chain K07374 TUBA; tubulin alpha
E 100920562 tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 100914278 LOW QUALITY PROTEIN: tubulin alpha chain K07374 TUBA; tubulin alpha
E 100923972 TUBA1C; tubulin alpha-1C chain K07374 TUBA; tubulin alpha
E 100927621 TUBA8; tubulin alpha-8 chain isoform X1 K07374 TUBA; tubulin alpha
E 105750812 LOW QUALITY PROTEIN: tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 100920490 tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 100923223 tubulin alpha-1C chain-like K07374 TUBA; tubulin alpha
E 116420883 tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 100934814 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100916666 CPEB2; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100920669 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100925745 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X2 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 100926792 GEMIN5; gem-associated protein 5 K13133 GEMIN5; gem associated protein 5
E 100914498 TACC3; transforming acidic coiled-coil-containing protein 3 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 100930328 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 100915787 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 100919165 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 100935273 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 100920654 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X9 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 100914563 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 100921184 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 100924852 CNOT6L; LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 100917730 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 100930215 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100925032 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100926528 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100929532 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100920088 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 116420259 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100935178 uncharacterized protein KIAA0355 homolog isoform X2 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 100927946 DIS3L2; DIS3-like exonuclease 2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 100932645 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 100930171 PAN3; LOW QUALITY PROTEIN: PAN2-PAN3 deadenylation complex subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 100923528 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 100922495 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 100919144 BTG4; protein BTG4 isoform X3 K14443 TOB; protein Tob/BTG
E 100921611 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 100927519 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 116421506 protein BTG2-like K14443 TOB; protein Tob/BTG
E 100930495 EIF4ENIF1; LOW QUALITY PROTEIN: eukaryotic translation initiation factor 4E transporter K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 100919450 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 100924593 EDC3; enhancer of mRNA-decapping protein 3 isoform X1 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 100915905 EDC4; enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 100923596 NANOS2; nanos homolog 2 K18760 NANOS2; protein nanos 2
E 100923928 NANOS3; nanos homolog 3 K18761 NANOS3; protein nanos 3
E 100930169 nanos homolog 3-like K18761 NANOS3; protein nanos 3
E 100930896 UPF2; regulator of nonsense transcripts 2 isoform X1 K14327 UPF2; regulator of nonsense transcripts 2
E 100918373 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 100913987 UPF3B; regulator of nonsense transcripts 3B K14328 UPF3; regulator of nonsense transcripts 3
E 100931045 probable E3 ubiquitin-protein ligase TRIML1 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
E 100931425 tripartite motif-containing protein 43-like K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
E 100916223 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 100913810 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 100931721 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase isoform X1 K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 100921049 ZAR1L; ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 105750907 ZAR1; zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 100916195 YTHDF2; YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
E 100918850 YTHDF1; YTH domain-containing family protein 1 isoform X2 K20102 YTHDF; YTH domain-containing family protein
E 100921752 YTHDF3; YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 100934734 TIAL1; nucleolysin TIAR isoform X3 K13201 TIA1; nucleolysin TIA-1/TIAR
E 100929282 TIA1; nucleolysin TIA-1 isoform X1 K13201 TIA1; nucleolysin TIA-1/TIAR
E 100933306 PABPC4; polyadenylate-binding protein 4 isoform X1 K13126 PABPC; polyadenylate-binding protein
E 100924794 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like K13126 PABPC; polyadenylate-binding protein
E 100913560 polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 100917652 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 100915293 PABPC1L; polyadenylate-binding protein 1-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 100923120 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X5 K17597 STAU; double-stranded RNA-binding protein Staufen
E 100930752 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 100915688 FXR2; fragile X mental retardation syndrome-related protein 2 K15516 FMR; fragile X mental retardation protein
E 100913594 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 100929616 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 100922443 ELAVL1; ELAV-like protein 1 isoform X1 K13088 ELAVL1; ELAV-like protein 1
E 100922339 G3BP1; ras GTPase-activating protein-binding protein 1 isoform X2 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 100916227 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X1 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 100923864 EIF2A; eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E 100913927 EIF3B; eukaryotic translation initiation factor 3 subunit B K03253 EIF3B; translation initiation factor 3 subunit B
E 100921249 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 100916209 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 100914020 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 100932538 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 100922583 EIF4B; eukaryotic translation initiation factor 4B K03258 EIF4B; translation initiation factor 4B
E 100927850 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100921634 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 K03260 EIF4G; translation initiation factor 4G
E 100933156 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 100923157 LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 100928498 RPS6KA6; ribosomal protein S6 kinase alpha-6 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 100931854 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X2 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 100931566 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X4 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 116422810 RPS6KA1; LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 100921089 RACK1; receptor of activated protein C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 100934749 TRAF2; TNF receptor-associated factor 2 isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 100918153 NXF1; nuclear RNA export factor 1 isoform X1 K14284 NXF; nuclear RNA export factor
E 100930397 HDAC6; histone deacetylase 6 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 100913773 TDRD3; tudor domain-containing protein 3 isoform X1 K18404 TDRD3; tudor domain-containing protein 3
E 100927875 LARP4; la-related protein 4 isoform X1 K18763 LARP4; la-related protein 4
E 100931337 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 100920013 DCP1A; mRNA-decapping enzyme 1A K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 100926238 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 100922624 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 100917240 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 100924593 EDC3; enhancer of mRNA-decapping protein 3 isoform X1 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 100915905 EDC4; enhancer of mRNA-decapping protein 4 isoform X1 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 100919450 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 100913641 LSM1; U6 snRNA-associated Sm-like protein LSm1 isoform X1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 100929839 LSM2; U6 snRNA-associated Sm-like protein LSm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 100924692 LOW QUALITY PROTEIN: U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 100918710 LSM3; U6 snRNA-associated Sm-like protein LSm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 100928431 LSM4; U6 snRNA-associated Sm-like protein LSm4 isoform X1 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 100917493 LSM5; U6 snRNA-associated Sm-like protein LSm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 100918491 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 100923315 LSM7; U6 snRNA-associated Sm-like protein LSm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 100917785 LSM8; LSM8 homolog, U6 small nuclear RNA associated K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 100934609 XRN1; 5'-3' exoribonuclease 1 isoform X1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 100926971 XRN2; 5'-3' exoribonuclease 2 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 100921288 NUDT16; U8 snoRNA-decapping enzyme K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 100935301 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 100913867 HELZ; probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 100930210 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
E 100929624 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 100929981 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 100921225 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 100921118 exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 116421279 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 100933501 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 100921939 EXOSC8; exosome complex component RRP43 K12586 RRP43; exosome complex component RRP43
E 100916940 EXOSC9; exosome complex component RRP45 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 100925695 DIS3; exosome complex exonuclease RRP44 isoform X1 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 100919363 DIS3L; DIS3-like exonuclease 1 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 100931745 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 100919469 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 100919729 MPHOSPH6; M-phase phosphoprotein 6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 100917791 probable ATP-dependent RNA helicase DDX60 isoform X1 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 100921222 TENT4A; terminal nucleotidyltransferase 4A isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 100929023 TENT4B; terminal nucleotidyltransferase 4B isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 100924627 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 100934235 MTREX; exosome RNA helicase MTR4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 100923697 SKIV2L; helicase SKI2W isoform X1 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 100926105 TTC37; tetratricopeptide repeat protein 37 isoform X2 K12600 SKI3; superkiller protein 3
E 100925814 WDR61; WD repeat-containing protein 61 isoform X1 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 100924852 CNOT6L; LOW QUALITY PROTEIN: CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 100917730 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 100935273 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 100920654 CNOT2; CCR4-NOT transcription complex subunit 2 isoform X9 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 100914563 CNOT3; CCR4-NOT transcription complex subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 100921184 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 100930215 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100925032 CNOT7; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100926528 CNOT8; CCR4-NOT transcription complex subunit 8 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100929532 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100920088 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 116420259 CCR4-NOT transcription complex subunit 7-like K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 100919854 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 100934539 CNOT10; CCR4-NOT transcription complex subunit 10 isoform X1 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 100932645 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 100930171 PAN3; LOW QUALITY PROTEIN: PAN2-PAN3 deadenylation complex subunit PAN3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 100915402 PARN; poly(A)-specific ribonuclease PARN K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 100925885 PNLDC1; poly(A)-specific ribonuclease PNLDC1 isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 100920813 DHX36; ATP-dependent DNA/RNA helicase DHX36 isoform X1 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 100923528 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 100922495 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 100919144 BTG4; protein BTG4 isoform X3 K14443 TOB; protein Tob/BTG
E 100921611 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 100927519 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 116421506 protein BTG2-like K14443 TOB; protein Tob/BTG
E 100930989 NOCT; nocturnin isoform X1 K18764 NOCT; nocturnin [EC:3.1.3.108]
E 100927111 ERI1; 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 100933549 ERI2; ERI1 exoribonuclease 2 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 100935301 DCPS; m7GpppX diphosphatase K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 111719426 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 100925290 IREB2; iron-responsive element-binding protein 2 K22416 IREB2; iron-responsive element-binding protein 2
E 100913867 HELZ; probable helicase with zinc finger domain K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 100915383 HELZ2; helicase with zinc finger domain 2 isoform X1 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 100929271 NRDE2; nuclear exosome regulator NRDE2 isoform X2 K26109 NRDE2; nuclear exosome regulator NRDE2
E 100928500 SAMD4A; protein Smaug homolog 1 isoform X5 K27396 SMG; protein Smaug
E 100919850 SAMD4B; protein Smaug homolog 2 K27396 SMG; protein Smaug
E 100917050 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 100931633 ribonuclease pancreatic-like K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 105749827 ribonuclease pancreatic K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 116421537 ribonuclease pancreatic-like K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 105749201 seminal ribonuclease-like K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 100930933 ribonuclease 4 K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 100931898 ribonuclease 8 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 100918838 RNASE8; ribonuclease 8 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 100924644 ZC3H12C; probable ribonuclease ZC3H12C K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 100934086 ZC3H12A; endoribonuclease ZC3H12A K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 100920157 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 100933068 ZC3H12D; probable ribonuclease ZC3H12D K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 100933882 DROSHA; ribonuclease 3 isoform X3 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 100932692 REXO2; oligoribonuclease, mitochondrial isoform X1 K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 100916218 ENO2; gamma-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 100924827 alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 100925341 enolase isoform X1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 100935309 ENO3; beta-enolase isoform X1 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 100933877 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 100929505 PFKL; ATP-dependent 6-phosphofructokinase, liver type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 100926683 PFKM; ATP-dependent 6-phosphofructokinase, muscle type K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 100932898 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 100922082 HSPA9; stress-70 protein, mitochondrial K04043 dnaK; molecular chaperone DnaK
E 100917239 HSPD1; 60 kDa heat shock protein, mitochondrial isoform X2 K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 100929624 EXOSC2; exosome complex component RRP4 K03679 RRP4; exosome complex component RRP4
E 100930210 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 100921225 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 100933501 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024