+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Shewanella sp. W3-18-1</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    Sputw3181_2191 CRISPR-associated protein, Cas1 family	K15342 cas1; CRISP-associated protein Cas1 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      Sputw3181_2190 CRISPR-associated helicase, Cas3 family	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
D      Sputw3181_2189 CRISPR-associated protein, Csy1 family	K19127 csy1; CRISPR-associated protein Csy1 
D      Sputw3181_2188 CRISPR-associated protein, Csy2 family	K19128 csy2; CRISPR-associated protein Csy2 
D      Sputw3181_2187 CRISPR-associated protein, Csy3 family	K19129 csy3; CRISPR-associated protein Csy3 
D      Sputw3181_2186 CRISPR-associated protein, Csy4 family	K19130 csy4; CRISPR-associated endonuclease Csy4 [EC:3.1.-.-] 
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    Sputw3181_0321 type I site-specific deoxyribonuclease, HsdR family	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    Sputw3181_1090 type III restriction enzyme, res subunit	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    Sputw3181_0318 restriction modification system DNA specificity domain	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    Sputw3181_1088 putative type I site-specific restriction-modification system, S subunit	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    Sputw3181_1087 N-6 DNA methylase	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
C    Sputw3181_0317 type I restriction-modification system, M subunit	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      Sputw3181_3844 DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
D      Sputw3181_2523 C-5 cytosine-specific DNA methylase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
C    Sputw3181_2485 HNH endonuclease	K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-] 
C    Sputw3181_0323 hypothetical protein	K07452 mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-] 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
D      Sputw3181_0309 HipA domain protein	K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1] 
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
D      Sputw3181_2597 phage shock protein C, PspC	K03973 pspC; phage shock protein C 
D      Sputw3181_2598 phage shock B family protein	K03970 pspB; phage shock protein B 
C    CcdB-CcdA
C    ParE-ParD
D      Sputw3181_0282 plasmid stabilization system	K19092 parE1_3_4; toxin ParE1/3/4 
C    Doc-Phd
C    HigB-HigA
D      Sputw3181_2197 protein of unknown function DUF955	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
D      Sputw3181_0313 putative DNA-binding protein	K18831 higA; HTH-type transcriptional regulator / antitoxin HigA 
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      Sputw3181_0394 cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      Sputw3181_3598 rod shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      Sputw3181_3400 DNA topoisomerase IV subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      Sputw3181_3402 DNA topoisomerase IV subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      Sputw3181_1509 glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      Sputw3181_3013 conserved hypothetical protein	K19168 cptA; toxin CptA 
D      Sputw3181_3014 protein of unknown function DUF339	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    Sputw3181_1862 cysteine desulfurase IscS	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023