+E Messenger RNA Biogenesis KO
#
Messenger RNA Biogenesis - Schistosoma haematobium (urinary blood fluke)
%
!
AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E MS3_00010447 hypothetical protein K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
D Cap binding complex
E MS3_00002926 NCBP1; Nuclear cap-binding protein subunit 1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E MS3_00007118 NCBP2; Nuclear cap-binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E MS3_00008761 NUDT21; Nudix hydrolase 21, chloroplastic K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E MS3_00007852 CPSF6_1; Cleavage and polyadenylation specificity factor subunit 6 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E MS3_00001579 CLP1_1; Cleavage polyadenylation factor subunit clp1, variant 2 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E MS3_00005644 PCF11_1; mRNA 3' end processing factor, variant 2 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E MS3_00006705 CPSF1; Cleavage and polyadenylation specificity factor subunit 1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E MS3_00009540 CPSF2_1; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E MS3_00005379 CPSF3_1; Cleavage and polyadenylation specificity factor subunit 3, variant 4 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E MS3_00007503 FIP1L1_1; pre-mRNA 3-end-processing factor fip1l1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E MS3_00001968 WDR33_1; WD repeat-containing protein 33, variant 3 K15542 PFS2; polyadenylation factor subunit 2
E MS3_00004384 WDR82_1; WD repeat-containing protein 82, variant 2 K14962 WDR82; COMPASS component SWD2
E MS3_00005074 PPP1CA_1; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, variant 2 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E MS3_00005275 GSP1_1; GTP-binding nuclear protein gsp1/Ran K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E MS3_00006168 PPP1CA_3; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, variant 4 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E MS3_00006605 CSTF1_1; cleavage stimulation factor, 3' pre-RNA, subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E MS3_00010650 CSTF2; Cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
E MS3_00003651 CSTF3; Cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
D U7-dependent histone pre-mRNA processing factors
E MS3_00006911 SNRPD3; Small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E MS3_00009540 CPSF2_1; cleavage and polyadenylation specificity factor subunit 2 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E MS3_00005379 CPSF3_1; Cleavage and polyadenylation specificity factor subunit 3, variant 4 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E MS3_00010650 CSTF2; Cleavage stimulation factor subunit 2 K14407 CSTF2; cleavage stimulation factor subunit 2
D DRB sensitivity inducing factor (DSIF) complex
E MS3_00008270 SUPT4H1; Transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E MS3_00007154 SUPT5H; Transcription elongation factor SPT5 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E MS3_00009168 METTL3_1; N6-adenosine-methyltransferase subunit mettl3 K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E MS3_00005337 METTL16; Methyltransferase-like protein 16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E MS3_00009173 hypothetical protein K22824 WTAP; pre-mRNA-splicing regulator WTAP
E MS3_00010430 hypothetical protein K22910 VIRMA; protein virilizer
E MS3_00005583 RBM15_1; RNA-binding protein 15 K13190 RBM15; RNA-binding protein 15
E MS3_00007825 RBM15_3; RNA-binding protein 15, variant 2 K13190 RBM15; RNA-binding protein 15
D Poly(A) addition factors
E MS3_00010834 hypothetical protein K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E MS3_00009700 PAPD4_1; Zinc finger, CCHC domain-containing protein K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
E MS3_00007823 BARD1_1; BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1
E MS3_00004487 hypothetical protein K23600 TARDBP; TAR DNA-binding protein 43
E MS3_00010502 hypothetical protein K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D MS3_00006507 hypothetical protein K13102 KIN; DNA/RNA-binding protein KIN17
D MS3_00006816 hypothetical protein K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D MS3_00008822 ARS2_1; Serrate RNA effector molecule K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E MS3_00010643 RBM8A_1; RNA-binding protein 8A, variant 2 K12876 RBM8A; RNA-binding protein 8A
E MS3_00011034 ALYREF2; Aly/REF export factor 2 K12881 THOC4; THO complex subunit 4
E MS3_00002897 EIF4A3; Eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E MS3_00006889 EIF4AIII; Eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E MS3_00011122 hypothetical protein K25178 CCDC174; coiled-coil domain-containing protein 174
E MS3_00003390 CASC3; Cancer susceptibility candidate 3 K14323 CASC3; protein CASC3
E MS3_00004901 hypothetical protein K13114 PNN; pinin
D TREX complex
E MS3_00020002 THOC1_1; THO complex subunit 1 K12878 THOC1; THO complex subunit 1
E MS3_00008099 THOC2_1; THO complex subunit 2 K12879 THOC2; THO complex subunit 2
E MS3_00009151 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E MS3_00011034 ALYREF2; Aly/REF export factor 2 K12881 THOC4; THO complex subunit 4
E MS3_00002012 THOC5_1; THO complex subunit 5 K13174 THOC5; THO complex subunit 5
E MS3_00001992 THOC7_1; THO complex subunit 7 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E MS3_00001019 ENY2; Transcription and mRNA export factor eny2 K11368 ENY2; enhancer of yellow 2 transcription factor
E MS3_00001707 CETN3_1; Centrin-3 K16466 CETN3; centrin-3
D Nuclear pore complex
E MS3_00000413 hypothetical protein K09291 TPR; nucleoprotein TPR
E MS3_00004110 RAE1_1; Poly(A)+ RNA export protein rae1, variant 3 K14298 RAE1; mRNA export factor
E MS3_00001895 SEC13_3; GTPase-activating protein S13, variant 2 K14004 SEC13; protein transport protein SEC13
E MS3_00010926 NUP85; Nucleoporin nup85 K14304 NUP85; nuclear pore complex protein Nup85
E MS3_00010473 NUP43; Nucleoporin Nup43 K14305 NUP43; nuclear pore complex protein Nup43
E MS3_00010710 NUP50; Nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E MS3_00007431 NUP54; Nuclear pore complex protein Nup54 K14308 NUP54; nuclear pore complex protein Nup54
E MS3_00005569 hypothetical protein K14318 NUP88; nuclear pore complex protein Nup88
E MS3_00003580 NUP93; Nucleoporin nup93 K14309 NUP93; nuclear pore complex protein Nup93
E MS3_00010628 NUP98; Nuclear pore complex protein Nup98-Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E MS3_00005915 hypothetical protein K14301 NUP107; nuclear pore complex protein Nup107
E MS3_00008966 hypothetical protein K14312 NUP155; nuclear pore complex protein Nup155
E MS3_00005930 NUP35_1; Nucleoporin nup35 K14313 NUP35; nuclear pore complex protein Nup53
E MS3_00002440 hypothetical protein K14310 NUP205; nuclear pore complex protein Nup205
E MS3_00001763 hypothetical protein K14314 NUP210; nuclear pore complex protein Nup210
E MS3_00010048 NTMT1_1; N-terminal Xaa-Pro-Lys N-methyltransferase 1 K14317 NUP214; nuclear pore complex protein Nup214
E MS3_00004113 SEH1L_1; Nucleoporin SEH1 K14299 SEH1; nucleoporin SEH1
E MS3_00001707 CETN3_1; Centrin-3 K16466 CETN3; centrin-3
D Ran-mediated transport factors
E MS3_00003318 hypothetical protein K07936 RAN; GTP-binding nuclear protein Ran
E MS3_00009501 ANP32A_1; Acidic leucine-rich nuclear phosphoprotein 32 member, variant 4 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E MS3_00003920 hypothetical protein K13525 VCP; transitional endoplasmic reticulum ATPase
E MS3_00001476 XPO1_1; Exportin-1, variant 2 K14290 XPO1; exportin-1
E MS3_00004821 XPO7_1; Exportin 7 K18460 XPO7; exportin-7
D eIF4F and regulatory proteins
E MS3_00006477 EIF4E; translation initiation factor eIF4E, variant 2 K03259 EIF4E; translation initiation factor 4E
E MS3_00004923 EIF4A2; Eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E MS3_00007113 EIF-4A_2; Eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E MS3_00010932 hypothetical protein K03260 EIF4G; translation initiation factor 4G
E MS3_00008703 EIF4B_1; Eukaryotic translation initiation factor 4B, variant 2 K03258 EIF4B; translation initiation factor 4B
E MS3_00007183 EIF4H_1; Eukaryotic translation initiation factor 4H, variant 5 K24086 EIF4H; translation initiation factor 4H
E MS3_00006770 FMR1_3; Synaptic functional regulator fmr1 K15516 FMR; fragile X mental retardation protein
E MS3_00010020 FMR1_4; Synaptic functional regulator fmr1, variant 2 K15516 FMR; fragile X mental retardation protein
E MS3_00005330 hypothetical protein K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E MS3_00006558 MRH4_1; RNA helicase K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E MS3_00006914 DDX3X_1; ATP-dependent RNA helicase ddx3x K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E MS3_00009629 DDX3X_2; ATP-dependent RNA helicase ddx3x K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E MS3_00007024 hypothetical protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E MS3_00003997 PABPC4_1; Polyadenylate-binding protein 4, variant 2 K13126 PABPC; polyadenylate-binding protein
E MS3_00007466 MCTS1_1; Malignant T-cell-amplified sequence 1 K07575 MCTS; malignant T-cell-amplified sequence
E MS3_00004480 hypothetical protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E MS3_00002057 hypothetical protein K14294 WIBG; partner of Y14 and mago
E MS3_00010922 hypothetical protein K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E MS3_00003722 HRB27C; Heteroproteinous nuclear ribonucleoprotein 27C, variant 2 K14411 MSI; RNA-binding protein Musashi
E MS3_00006038 MSI2_3; RNA-binding protein Musashi 2 K14411 MSI; RNA-binding protein Musashi
E MS3_00002602 HBS1L_1; HBS1-like protein, variant 2 K14416 HBS1; elongation factor 1 alpha-like protein
E MS3_00010723 hypothetical protein K06965 PELO; protein pelota
E MS3_00010322 PABPN1; Polyadenylate-binding protein 2 K14396 PABPN1; polyadenylate-binding protein 2
E MS3_00008928 XAB2; Pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E MS3_00009741 hypothetical protein K18732 SARNP; SAP domain-containing ribonucleoprotein
E MS3_00005173 hypothetical protein K21772 PURA; transcriptional activator protein Pur-alpha
E MS3_00007410 hypothetical protein K21772 PURA; transcriptional activator protein Pur-alpha
E MS3_00009094 POLDIP3; polymerase delta-interacting protein 3 K22414 POLDIP3; polymerase delta-interacting protein 3
E MS3_00002646 LENG8_1; Leukocyte receptor cluster (LRC) member 8, variant 3 K23802 LENG8; SAC3 family protein LENG8/THP3
E MS3_00010863 LENG8_4; Leukocyte receptor cluster (LRC) member 8 K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E MS3_00006447 ERF1; translation termination factor eRF1 K03265 ETF1; peptide chain release factor subunit 1
E MS3_00001494 GSPT1_1; Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, variant 2 K03267 ERF3; peptide chain release factor subunit 3
E MS3_00010794 UPF2; Regulator of nonsense transcripts upf2 K14327 UPF2; regulator of nonsense transcripts 2
D Protein phosphatase 2A
E MS3_00009383 PPP2CA; serine threonine-protein phosphatase K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E MS3_00003478 PPP2R1A_1; Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E MS3_00009205 hypothetical protein K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E MS3_00004915 PPP2R2B_1; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E MS3_00004528 PPP2R3C_1; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E MS3_00004551 PPP2R3C_2; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E MS3_00009770 PPP2R3C_3; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E MS3_00005519 PPP2R5A_1; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E MS3_00009073 PPP2R5D_1; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E MS3_00004091 SMG1_1; Serine/threonine-protein kinase smg1, variant 2 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E MS3_00007514 SMG5_1; Protein smg5 K11125 SMG5; protein SMG5
E MS3_00006041 SMG6; Smg-6, nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E MS3_00006850 SMG8; Protein smg8 K18734 SMG8; protein SMG8
E MS3_00007024 hypothetical protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E MS3_00001629 SECISBP2L; Selenocysteine insertion sequence-binding protein 2-like K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E MS3_00006373 DHX34_1; DEAH (Asp-Glu-Ala-His) box polypeptide 34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E MS3_00008976 DGP-1; Short integuments 2, mitochondrial K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E MS3_00008370 PUM3_1; Pumilio 3, variant 2 K14844 PUF6; pumilio homology domain family member 6
E MS3_00001512 BICD2_1; Protein bicaudal D 2 K18739 BICD; protein bicaudal D
D Factors that have mRNA localization signals
E MS3_00004525 ACT1_1; actin, variant 2 K05692 ACTB_G1; actin beta/gamma 1
E MS3_00008660 ACTIN1_1; Actin-1 K05692 ACTB_G1; actin beta/gamma 1
E MS3_00008661 ACTIN1_2; Actin-1 K05692 ACTB_G1; actin beta/gamma 1
E MS3_00008744 ARP1_3; centractin- actin- protein of the dynactin complex K05692 ACTB_G1; actin beta/gamma 1
E MS3_00008746 hypothetical protein K05692 ACTB_G1; actin beta/gamma 1
D Trans-acting binding proteins
E MS3_00010338 FUBP1; Far upstream element-binding protein 1 K13210 FUBP; far upstream element-binding protein
E MS3_00002114 EEF1A1_1; Elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E MS3_00002266 hypothetical protein K17597 STAU; double-stranded RNA-binding protein Staufen
E MS3_00003096 PTBP2_1; Polypyrimidine tract-binding protein 2 K13218 PTBP1; polypyrimidine tract-binding protein 1
E MS3_00010567 PTBP2_2; Polypyrimidine tract-binding protein 2 K13218 PTBP1; polypyrimidine tract-binding protein 1
E MS3_00005330 hypothetical protein K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E MS3_00006770 FMR1_3; Synaptic functional regulator fmr1 K15516 FMR; fragile X mental retardation protein
E MS3_00010020 FMR1_4; Synaptic functional regulator fmr1, variant 2 K15516 FMR; fragile X mental retardation protein
E MS3_00005279 CAPRIN1_1; Caprin1p, variant 2 K18743 CAPRIN1; caprin-1
E MS3_00004812 YBX1_1; Y box binding protein 1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E MS3_00009573 XRN1_1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E MS3_00001643 AGO2_4; Protein argonaute-2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E MS3_00009538 AGO1_1; argonaute 1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E MS3_00006477 EIF4E; translation initiation factor eIF4E, variant 2 K03259 EIF4E; translation initiation factor 4E
E MS3_00006558 MRH4_1; RNA helicase K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E MS3_00006914 DDX3X_1; ATP-dependent RNA helicase ddx3x K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E MS3_00009629 DDX3X_2; ATP-dependent RNA helicase ddx3x K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E MS3_00006414 DDX6_1; putative ATP-dependent RNA helicase ddx6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E MS3_00004812 YBX1_1; Y box binding protein 1 K09276 YBX1; Y-box-binding protein 1
E MS3_00004094 TNPO1; Transportin-1 K18752 TNPO1; transportin-1
E MS3_00004091 SMG1_1; Serine/threonine-protein kinase smg1, variant 2 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E MS3_00007514 SMG5_1; Protein smg5 K11125 SMG5; protein SMG5
E MS3_00006041 SMG6; Smg-6, nonsense mediated mRNA decay factor K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E MS3_00004397 SNAI2_2; Snail 2 K04533 HD; huntingtin
E MS3_00010922 hypothetical protein K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E MS3_00002636 PKA-C1_1; cAMP-dependent protein kinase catalytic subunit 1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E MS3_00003633 hypothetical protein K04345 PKA; protein kinase A [EC:2.7.11.11]
E MS3_00008673 PKA1_5; camp-dependent protein kinase catalytic subunit K04345 PKA; protein kinase A [EC:2.7.11.11]
E MS3_00008682 hypothetical protein K04345 PKA; protein kinase A [EC:2.7.11.11]
E MS3_00006001 LARP1_1; La ribonucleoprotein domain member 1 K18757 LARP1; la-related protein 1
E MS3_00006956 hypothetical protein K18757 LARP1; la-related protein 1
D P-body specific factors
E MS3_00003123 DCP2; mRNA-decapping enzyme subunit 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E MS3_00007529 DCP1B; mRNA-decapping enzyme 1B K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E MS3_00006528 LSM3; U4/U6-U5 snRNP complex subunit lsm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E MS3_00003732 LSM4_1; RNA processing protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E MS3_00001588 hypothetical protein K10407 KLC; kinesin light chain
E MS3_00005438 MEC-12_1; Tubulin K07374 TUBA; tubulin alpha
E MS3_00008342 TUBA3D_3; Tubulin alpha-3C/D chain, variant 2 K07374 TUBA; tubulin alpha
E MS3_00008742 TUBA3D_5; Tubulin alpha-3C/D chain K07374 TUBA; tubulin alpha
E MS3_00005330 hypothetical protein K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E MS3_00007082 CNOT3_1; CCR4-NOT transcription complex, subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E MS3_00003467 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E MS3_00007016 CNOT7_1; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E MS3_00007730 PAN3_1; PAB-dependent poly(A)-specific ribonuclease subunit 3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E MS3_00010794 UPF2; Regulator of nonsense transcripts upf2 K14327 UPF2; regulator of nonsense transcripts 2
E MS3_00002220 YTHDF2; YTH domain-containing protein 2 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E MS3_00003997 PABPC4_1; Polyadenylate-binding protein 4, variant 2 K13126 PABPC; polyadenylate-binding protein
E MS3_00002266 hypothetical protein K17597 STAU; double-stranded RNA-binding protein Staufen
E MS3_00006770 FMR1_3; Synaptic functional regulator fmr1 K15516 FMR; fragile X mental retardation protein
E MS3_00010020 FMR1_4; Synaptic functional regulator fmr1, variant 2 K15516 FMR; fragile X mental retardation protein
E MS3_00010078 EIF2A; Eukaryotic translation initiation factor 2A K15026 EIF2A; translation initiation factor 2A
E MS3_00003828 EIF3B; translation initiation factor eIF-3b like protein K03253 EIF3B; translation initiation factor 3 subunit B
E MS3_00004923 EIF4A2; Eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E MS3_00007113 EIF-4A_2; Eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E MS3_00002897 EIF4A3; Eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E MS3_00006889 EIF4AIII; Eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E MS3_00008703 EIF4B_1; Eukaryotic translation initiation factor 4B, variant 2 K03258 EIF4B; translation initiation factor 4B
E MS3_00010932 hypothetical protein K03260 EIF4G; translation initiation factor 4G
E MS3_00010396 RPS6KA1; Ribosomal protein S6 kinase alpha-1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E MS3_00009270 GNB2L1; Guanine nucleotide-binding protein subunit beta-2-like 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E MS3_00007529 DCP1B; mRNA-decapping enzyme 1B K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E MS3_00003123 DCP2; mRNA-decapping enzyme subunit 2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E MS3_00006414 DDX6_1; putative ATP-dependent RNA helicase ddx6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
D Lsm complex
E MS3_00006528 LSM3; U4/U6-U5 snRNP complex subunit lsm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E MS3_00003732 LSM4_1; RNA processing protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
D 5' exonucleases
E MS3_00009573 XRN1_1; 5'-3' exoribonuclease 1 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D Other 5'-3' decay factors
E MS3_00003873 hypothetical protein K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
C 3'-5' decay
D Core exosome factors
E MS3_00003358 EXOSC4; Exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E MS3_00006233 EXOSC7; Exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E MS3_00002559 EXOSC9_1; Exosome complex component RRP45, variant 2 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E MS3_00003263 DIS3L_1; DIS3 mitotic control K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E MS3_00006116 EXOSC10; Exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E MS3_00006351 C1D; DNA-binding protein c1d K12592 C1D; exosome complex protein LRP1
D TRAMP complex
E MS3_00003317 PAPD5_1; Non-canonical poly(A) RNA polymerase papd5, variant 2 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E MS3_00004207 hypothetical protein K12597 AIR1_2; protein AIR1/2
D Ski complex
D Ccr4-NOT complex
E MS3_00003467 CNOT6L; CCR4-NOT transcription complex subunit 6-like K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E MS3_00007082 CNOT3_1; CCR4-NOT transcription complex, subunit 3 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E MS3_00007016 CNOT7_1; CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
D Pan complex
E MS3_00007730 PAN3_1; PAB-dependent poly(A)-specific ribonuclease subunit 3 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E MS3_00009800 DHX36; ATP-dependent DNA/RNA helicase dhx36 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E MS3_00001426 CCRN4L; Nocturnin K18764 NOCT; nocturnin [EC:3.1.3.108]
E MS3_00003873 hypothetical protein K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E MS3_00003727 hypothetical protein K26109 NRDE2; nuclear exosome regulator NRDE2
C Other degradation factors
D RNases
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E MS3_00006970 hypothetical protein K03685 rnc; ribonuclease III [EC:3.1.26.3]
D Helicases
D Other RNA degradosome components
E MS3_00009179 hypothetical protein K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E MS3_00005263 HSPA9_1; Stress-70 protein, mitochondrial, variant 4 K04043 dnaK; molecular chaperone DnaK
E MS3_00008075 HSPD1_1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
D Cofactors
E MS3_00003358 EXOSC4; Exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E MS3_00006233 EXOSC7; Exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024