+F Repair protein KO #

  DNA Repair and Recombination Proteins - Schistosoma haematobium (urinary blood fluke)

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AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D MS3_00009105 ASCC3_3; activating signal cointegrator 1 complex subunit K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4] D MS3_00001871 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D MS3_00009640 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E MS3_00010962 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E MS3_00007248 hypothetical protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29] D AP endonucleases E MS3_00004951 APEX2_1; DNA-(apurinic or apyrimidinic site) lyase 2, variant 2 K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2] D Long Patch-BER factors E DNA polymerase delta complex F MS3_00008164 POLD1_1; DNA polymerase delta catalytic subunit, variant 2 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] F MS3_00004496 POLD2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2 F MS3_00006592 POLD3; DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3 E DNA polymerase epsilon complex F MS3_00003159 hypothetical protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7] F MS3_00002446 POLE2; DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7] F MS3_00009146 POLE3_1; DNA polymerase epsilon subunit 3, variant 2 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7] F MS3_00006376 hypothetical protein K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7] E MS3_00008653 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen D Short Patch-BER factors E MS3_00010581 XRCC1; DNA repair protein xrcc1 K10803 XRCC1; DNA-repair protein XRCC1 D Other BER factors E MS3_00008597 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex F MS3_00002658 MED18; Mediator of RNA polymerase II transcription subunit 18 K10838 XPC; xeroderma pigmentosum group C-complementing protein F MS3_00003893 RAD23B_1; UV excision repair protein RAD23 B, variant 2 K10839 RAD23; UV excision repair protein RAD23 E Cul4-DDB2 complex F MS3_00007295 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1 E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex F MS3_00007736 POLR2A_1; DNA-directed RNA polymerase II subunit RPB1, variant 3 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] F MS3_00002590 POLR2B; DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] F MS3_00011081 POLR2D; DNA-directed RNA polymerase II subunit rpb4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4 F MS3_00003285 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2 F MS3_00001873 POLR2H_1; DNA-directed RNA polymerases I, II, and III subunit RPABC3, variant 2 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3 F MS3_00004111 POLR2I_1; DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 F MS3_00004220 POLR2I_2; DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9 F MS3_00005819 POLR2J_1; DNA-directed RNA polymerase II subunit RPB11-a K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11 E Cul4-CSA complex F MS3_00007295 DDB1; DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1 E Other TCR factor F MS3_00010410 ERCC6; DNA excision repair protein ERCC-6 K10841 ERCC6; DNA excision repair protein ERCC-6 D TFIIH complex E MS3_00003304 ERCC3; TFIIH basal transcription factor complex helicase XPB subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] E MS3_00007033 ERCC2_1; General transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] E MS3_00003347 GTF2H1_1; General transcription factor IIH subunit 1, variant 2 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1 E MS3_00004671 GTF2H2; General transcription factor IIH subunit 2 K03142 TFIIH2; transcription initiation factor TFIIH subunit 2 E MS3_00010812 GTF2H4_1; General transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4 D RPA (replication factor A) E MS3_00004984 RPA1; 60S acidic ribosomal protein P1 K07466 RFA1; replication factor A1 E MS3_00003299 RPA2_1; DNA-directed RNA polymerase I subunit rpa2 K10739 RFA2; replication factor A2 D Other NER factors E MS3_00020013 ERCC1; Excision repair cross-complementation group 1 K10849 ERCC1; DNA excision repair protein ERCC-1 E MS3_00010762 MMS19; mms19 nucleotide excision repair K15075 MET18; DNA repair/transcription protein MET18/MMS19 E MS3_00002896 CUL3; Cullin-3 K03869 CUL3; cullin 3 E MS3_00002720 CUL5_1; Cullin-5, variant 2 K10612 CUL5; cullin 5 E MS3_00008308 TCEB1; Transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) K03872 ELOC; elongin-C E MS3_00002081 TCEB2; Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) K03873 ELOB; elongin-B E MS3_00002322 TCEB3_1; Elongin-A K15076 ELOA; elongin-A C MMR (mismatch excision repair) D Mismatch and loop recognition factors E MS3_00007671 MSH6; DNA mismatch repair protein msh6 K08737 MSH6; DNA mismatch repair protein MSH6 D MutL homologs E MS3_00010790 MLH1; DNA mismatch repair protein K08734 MLH1; DNA mismatch repair protein MLH1 D DNA polymerase delta complex E MS3_00008164 POLD1_1; DNA polymerase delta catalytic subunit, variant 2 K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7] E MS3_00004496 POLD2; DNA polymerase delta subunit 2 K02328 POLD2; DNA polymerase delta subunit 2 E MS3_00006592 POLD3; DNA polymerase delta subunit 3 K03504 POLD3; DNA polymerase delta subunit 3 D RPA (replication factor A) E MS3_00004984 RPA1; 60S acidic ribosomal protein P1 K07466 RFA1; replication factor A1 E MS3_00003299 RPA2_1; DNA-directed RNA polymerase I subunit rpa2 K10739 RFA2; replication factor A2 D RFC (replication factor C) E MS3_00002072 RFC1_1; replication factor C subunit 1, variant 2 K10754 RFC1; replication factor C subunit 1 E MS3_00004502 RFC4_1; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4 E MS3_00006019 RFC5_1; Replication factor C (RF-C) subunit, variant 4 K10756 RFC3_5; replication factor C subunit 3/5 E MS3_00007838 RFC3_1; Subunit of heteropentameric Replication factor C (RF-C), variant 2 K10756 RFC3_5; replication factor C subunit 3/5 D Other MMR factors E MS3_00008653 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen E MS3_00008302 EXO1; Rad2 nuclease K10746 EXO1; exonuclease 1 [EC:3.1.-.-] B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex E MS3_00005494 BRCA1; Breast cancer 1, early onset K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E MS3_00007823 BARD1_1; BRCA1-associated RING domain protein 1 K10683 BARD1; BRCA1-associated RING domain protein 1 D BRCA1-A complex E MS3_00005494 BRCA1; Breast cancer 1, early onset K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] D BRCA1-B complex E MS3_00005494 BRCA1; Breast cancer 1, early onset K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E MS3_00007015 TOPBP1; DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1 D BRCA1-C complex E MS3_00005494 BRCA1; Breast cancer 1, early onset K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] D BRCA complex E MS3_00005494 BRCA1; Breast cancer 1, early onset K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] E MS3_00002292 RAD51_1; recombinase rad51 K04482 RAD51; DNA repair protein RAD51 D RecA family proteins E MS3_00002292 RAD51_1; recombinase rad51 K04482 RAD51; DNA repair protein RAD51 D Rad52 family proteins D Rad54 family proteins E MS3_00004057 RAD54L_1; DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-] E MS3_00000157 hypothetical protein K10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-] E MS3_00008065 RAD54B_3; DNA repair and recombination protein rad54b K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-] D RecQ family DNA helicases E MS3_00007313 hypothetical protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4] E MS3_00000016 RECQL4; ATP-dependent DNA helicase Q4 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4] D Bloom's syndrome complex (BTR) E MS3_00005400 TOP3B_1; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E MS3_00011066 TOP3A; DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] D RPA (replication factor A) E MS3_00004984 RPA1; 60S acidic ribosomal protein P1 K07466 RFA1; replication factor A1 E MS3_00003299 RPA2_1; DNA-directed RNA polymerase I subunit rpa2 K10739 RFA2; replication factor A2 D Protein phosphatase 4 E MS3_00004757 PPP4C_1; Serine/threonine-protein phosphatase 4 catalytic subunit, variant 2 K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] E MS3_00008633 PPP4R2_1; protein phosphatase 4, regulatory subunit 2 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2 D AP-5 complex D SMC5-SMC6 complex D Other HR factors E MS3_00009317 EME1; crossover junction endonuclease eme1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-] E MS3_00007323 MUS81_1; Crossover junction endonuclease mus81 K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-] E MS3_00005273 SLX1A; Structure-specific endonuclease subunit SLX1 K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] E MS3_00005407 GEN1_1; Flap endonuclease GEN 1 K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-] E MS3_00006779 Mortality factor 4-like protein 2 K11339 MORF4L1; mortality factor 4-like protein 1 E MS3_00006381 SAMHD1; SAM domain and HD K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-] E MS3_00005896 MCM9; DNA helicase mcm9 K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4] C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex E MS3_00001971 LIG4_1; DNA ligase (ATP), variant 2 K10777 LIG4; DNA ligase 4 [EC:6.5.1.1] D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) E MS3_00005400 TOP3B_1; DNA topoisomerase 3-beta-1 K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] E MS3_00011066 TOP3A; DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1] D FANCD2-I complex D Downstream FA components E MS3_00005494 BRCA1; Breast cancer 1, early onset K10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27] D Other FA pathway factors E MS3_00005334 FAN1_1; Fanconi-associated nuclease 1 K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] E MS3_00002292 RAD51_1; recombinase rad51 K04482 RAD51; DNA repair protein RAD51 C Other DSBR factors D Protein phosphatase 6 E MS3_00010785 PPP6C; Serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] D Ubiquitin ligases D Others E MS3_00006945 WRAP53; Telomerase Cajal body protein 1 K23314 WRAP53; telomerase Cajal body protein 1 E MS3_00004853 WDR70; WD repeat-containing protein 70 K24752 WDR70; WD repeat-containing protein 70 B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D MS3_00009913 hypothetical protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7] D MS3_00006202 hypothetical protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7] C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group D MS3_00001403 UBE2A_1; Ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D MS3_00008162 UBE2A_2; Ubiquitin-conjugating enzyme E2 A, variant 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23] D MS3_00004990 UBE2N_1; ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23] C Other TLS factors D MS3_00008653 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen D MS3_00001419 hypothetical protein K24051 SPRTN; SprT-like domain-contaning protein Spartan D MS3_00005313 hypothetical protein K26957 GCNA; germ cell nuclear acidic protein B Check point factors C Rad9-Hus1-Rad1 complex D MS3_00005172 RAD1; ssDNA endodeoxyribonuclease K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C HRAD17(Rad24)-RFC complex D MS3_00004409 RAD17_1; Cell cycle checkpoint protein rad17 K06662 HRAD17; cell cycle checkpoint protein D MS3_00004502 RFC4_1; replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4 D MS3_00006019 RFC5_1; Replication factor C (RF-C) subunit, variant 4 K10756 RFC3_5; replication factor C subunit 3/5 D MS3_00007838 RFC3_1; Subunit of heteropentameric Replication factor C (RF-C), variant 2 K10756 RFC3_5; replication factor C subunit 3/5 C Rad17-Mec3-Ddc1 complex D MS3_00005172 RAD1; ssDNA endodeoxyribonuclease K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2] C FPC (fork protection complex) D MS3_00003865 hypothetical protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1 C Triple T complex D MS3_00010825 hypothetical protein K20403 TTI1; TELO2-interacting protein 1 C BAG6-UBL4A-GET4 complex D MS3_00010116 hypothetical protein K23390 BAG6; large proline-rich protein BAG6 D MS3_00004846 UBL4A; Ubiquitin-like protein 4A K23388 UBL4; ubiquitin-like protein 4 D MS3_00010972 GET4_1; Golgi to ER traffic protein 4 K23387 GET4; golgi to ER traffic protein 4 C Other check point factors D MS3_00004189 hypothetical protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1] D MS3_00004470 CHEK1; Serine/threonine-protein kinase Chk1 K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1] D MS3_00007174 CHEK2_2; Checkpoint kinase 2, variant 3 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1] D MS3_00009588 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D MS3_00010172 hypothetical protein K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta D MS3_00006039 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon D MS3_00006801 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon D MS3_00003144 WEE1_1; Mitosis inhibitor protein kinase wee1 K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1] D MS3_00007260 PLS1_1; phospholipid scramblase 1 K17336 PLS3; plastin-3 D MS3_00008214 PLS1_2; phospholipid scramblase 1, variant 2 K17336 PLS3; plastin-3 D MS3_00001622 NEK10; Serine/threonine-protein kinase Nek10 K20879 NEK10; serine/threonine-protein kinase Nek10 [EC:2.7.11.1] D MS3_00004326 KANK1_1; KN motif and ankyrin repeat domain, variant 2 K22808 KANK; KN motif and ankyrin repeat domain-containing protein D MS3_00010408 VPS4; Vacuolar protein sorting-associated protein 4 K12196 VPS4; vacuolar protein-sorting-associated protein 4 D MS3_00003241 SDE2_1; silencing defective protein Sde2, variant 2 K25059 SDE2; replication stress response regulator SDE2 B Other factors with a suspected DNA repair function C DNA polymerases D MS3_00009108 MYBBP1A; Myb-binding protein 1A K02331 POL5; DNA polymerase phi [EC:2.7.7.7] C Nucleases D MS3_00006820 TREX1_1; Three-prime repair exonuclease 1 K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2] C Helicases D MS3_00003264 hypothetical protein K19178 HELQ; POLQ-like helicase [EC:5.6.2.4] C PSO4 complex D MS3_00009054 CDC5L_1; CDC5 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1 D MS3_00001850 BCAS2; Pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27 D MS3_00007854 hypothetical protein K12862 PLRG1; pleiotropic regulator 1 C Modulation of nucleotide pools D MS3_00003307 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D MS3_00004217 RRM2; Ribonucleoside-diphosphate reductase subunit M2 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D MS3_00001871 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D MS3_00009640 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E MS3_00010962 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] D AP endonucleases D RecJ D DNA ligase D DNA polymerase I C NER (nucleotide excision repair) D GGR (global genome repair) factors D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) E TRCF (transcription-repair coupling factor) C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases D DNA polymerase III holoenzyme D DNA ligase D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins D RecFOR pathway proteins D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator E Supressor D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway E Facilitator E Supressor B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C Other SOS response factors B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases C Modulation of nucleotide pools D MS3_00003307 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025