+D GENES KO
#
KEGG Orthology (KO) - Sulfolobus islandicus HVE10/4
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:sih00010]
D SiH_0093 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D SiH_2084 Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SiH_1791 conserved hypothetical protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D SiH_2678 Triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D SiH_1548 glyceraldehyde-3-phosphate dehydrogenase, type II K00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]
D SiH_1547 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D SiH_0053 phosphoglycerate mutase K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SiH_1662 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D SiH_1253 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SiH_1187 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SiH_1281 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D SiH_0582 dehydrogenase complex, dihydrolipoamide acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_2425 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SiH_2424 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SiH_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0994 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0298 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0033 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0576 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0727 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0496 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_2388 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0614 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0624 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0646 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0681 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D SiH_2514 Aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_2110 Aldehyde Dehydrogenase K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90]
D SiH_0993 Phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
C 00020 Citrate cycle (TCA cycle) [PATH:sih00020]
D SiH_2681 2-methylcitrate synthase/citrate synthase II K01647 CS; citrate synthase [EC:2.3.3.1]
D SiH_1092 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D SiH_2759 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2425 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SiH_2424 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SiH_0281 ATP-citrate lyase/succinyl-CoA ligase K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SiH_0282 Succinate--CoA ligase (ADP-forming) K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SiH_0159 succinate dehydrogenase or fumarate reductase,flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SiH_0160 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SiH_0161 CoB-CoM heterodisulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SiH_0162 succinate dehydrogenase subunit D (SdhD) K18859 sdhD; succinate dehydrogenase subunit D
D SiH_1107 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D SiH_2685 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SiH_0993 Phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
D SiH_0582 dehydrogenase complex, dihydrolipoamide acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00030 Pentose phosphate pathway [PATH:sih00030]
D SiH_0093 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D SiH_1776 transketolase, N-terminal subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D SiH_1778 transketolase, C-terminal subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D SiH_1189 ribose 5-phosphate isomerase K01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]
D SiH_1876 Orotidine 5'-phosphate decarboxylase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D SiH_1931 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D SiH_0244 PfkB domain protein K00852 rbsK; ribokinase [EC:2.7.1.15]
D SiH_2059 ribokinase K00852 rbsK; ribokinase [EC:2.7.1.15]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_1136 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SiH_2108 dihydrodipicolinate synthetase K11395 kdpgA; 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase [EC:4.1.2.55]
D SiH_2110 Aldehyde Dehydrogenase K18978 gapN; glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+] [EC:1.2.1.90]
D SiH_2256 Alcohol dehydrogenase GroES domain protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359]
D SiH_2295 Alcohol dehydrogenase GroES domain protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359]
D SiH_2102 Alcohol dehydrogenase GroES domain protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359]
D SiH_2107 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D SiH_2603 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D SiH_2109 PfkB domain protein K18126 sskdgK; 2-dehydro-3-deoxygluconokinase / 2-dehydro-3-deoxygalactonokinase [EC:2.7.1.178]
D SiH_2626 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein K18020 cutA; glyceraldehyde dehydrogenase large subunit [EC:1.2.99.8]
D SiH_2628 molybdopterin dehydrogenase FAD-binding protein K18021 cutB; glyceraldehyde dehydrogenase medium subunit [EC:1.2.99.8]
D SiH_2627 (2Fe-2S)-binding domain protein K18022 cutC; glyceraldehyde dehydrogenase small subunit [EC:1.2.99.8]
D SiH_1407 Hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SiH_2084 Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SiH_1791 conserved hypothetical protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
C 00040 Pentose and glucuronate interconversions [PATH:sih00040]
D SiH_2259 Beta-glucuronidase K01195 uidA; beta-glucuronidase [EC:3.2.1.31]
D SiH_0532 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SiH_0475 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SiH_0533 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_0476 nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_2076 Alcohol dehydrogenase GroES domain protein K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14]
D SiH_2188 fumarylacetoacetate (FAA) hydrolase K14259 kdaD; 2-dehydro-3-deoxy-D-arabinonate dehydratase [EC:4.2.1.141]
D SiH_2189 Aldehyde Dehydrogenase K19588 dopDH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
D SiH_0885 class II aldolase/adducin family protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
C 00051 Fructose and mannose metabolism [PATH:sih00051]
D SiH_0093 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_1760 Nucleotidyl transferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
D SiH_0885 class II aldolase/adducin family protein K01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]
D SiH_0793 Mandelate racemase/muconate lactonizing protein K12661 LRA3; L-rhamnonate dehydratase [EC:4.2.1.90]
D SiH_2076 Alcohol dehydrogenase GroES domain protein K00008 SORD; L-iditol 2-dehydrogenase [EC:1.1.1.14]
D SiH_2084 Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SiH_1791 conserved hypothetical protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D SiH_2678 Triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 00052 Galactose metabolism [PATH:sih00052]
D SiH_2514 Aldose 1-epimerase K01785 galM; aldose 1-epimerase [EC:5.1.3.3]
D SiH_1918 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D SiH_0533 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_0476 nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_2277 glycoside hydrolase family 1 K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D SiH_2256 Alcohol dehydrogenase GroES domain protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359]
D SiH_2295 Alcohol dehydrogenase GroES domain protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359]
D SiH_2102 Alcohol dehydrogenase GroES domain protein K18125 ssgdh; aldose 1-dehydrogenase [NAD(P)+] [EC:1.1.1.359]
D SiH_2107 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D SiH_2603 Mandelate racemase/muconate lactonizing protein K05308 gnaD; gluconate/galactonate dehydratase [EC:4.2.1.140]
D SiH_2108 dihydrodipicolinate synthetase K11395 kdpgA; 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase [EC:4.1.2.55]
D SiH_2109 PfkB domain protein K18126 sskdgK; 2-dehydro-3-deoxygluconokinase / 2-dehydro-3-deoxygalactonokinase [EC:2.7.1.178]
D SiH_2248 Alpha-glucosidase K01187 malZ; alpha-glucosidase [EC:3.2.1.20]
C 00053 Ascorbate and aldarate metabolism [PATH:sih00053]
D SiH_0532 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SiH_0475 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SiH_2259 Beta-glucuronidase K01195 uidA; beta-glucuronidase [EC:3.2.1.31]
D SiH_0792 Alcohol dehydrogenase GroES domain protein K19590 araDH; D-arabinose 1-dehydrogenase (NADP+) [EC:1.1.1.427]
D SiH_2184 Mandelate racemase/muconate lactonizing protein K01683 araD; D-arabinonate dehydratase [EC:4.2.1.5]
D SiH_2188 fumarylacetoacetate (FAA) hydrolase K14259 kdaD; 2-dehydro-3-deoxy-D-arabinonate dehydratase [EC:4.2.1.141]
D SiH_2189 Aldehyde Dehydrogenase K19588 dopDH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
C 00500 Starch and sucrose metabolism [PATH:sih00500]
D SiH_2248 Alpha-glucosidase K01187 malZ; alpha-glucosidase [EC:3.2.1.20]
D SiH_0533 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_0476 nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_1183 starch synthase K00703 glgA; starch synthase [EC:2.4.1.21]
D SiH_0992 glycosyl transferase group 1 K00688 PYG; glycogen phosphorylase [EC:2.4.1.1]
D SiH_1182 alpha-amylase K07405 E3.2.1.1A; alpha-amylase [EC:3.2.1.1]
D SiH_0268 glycoside hydrolase 15-related protein K01178 SGA1; glucoamylase [EC:3.2.1.3]
D SiH_0856 glycogen debranching enzyme GlgX K01214 ISA; isoamylase [EC:3.2.1.68]
D SiH_0855 malto-oligosyltrehalose synthase K06044 treY; (1->4)-alpha-D-glucan 1-alpha-D-glucosylmutase [EC:5.4.99.15]
D SiH_0857 malto-oligosyltrehalose trehalohydrolase K01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141]
D SiH_2660 glycosyl transferase group 1 K13057 treT; trehalose synthase [EC:2.4.1.245]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_0093 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
C 00520 Amino sugar and nucleotide sugar metabolism [PATH:sih00520]
D SiH_2594 N-acetylglucosamine-6-phosphate deacetylase K01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]
D SiH_1699 glucosamine-fructose-6-phosphateamino transferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SiH_0946 glutamine amidotransferase class-II K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SiH_1343 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D SiH_2250 oxidoreductase domain protein K13020 wlbA; UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase [EC:1.1.1.335]
D SiH_0531 NAD-dependent epimerase/dehydratase K08678 UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35]
D SiH_0474 NAD-dependent epimerase/dehydratase K08678 UXS1; UDP-glucuronate decarboxylase [EC:4.1.1.35]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_0533 Nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_0476 nucleotidyl transferase K00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]
D SiH_0532 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SiH_0475 nucleotide sugar dehydrogenase K00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]
D SiH_2686 NAD-dependent epimerase/dehydratase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
D SiH_1918 NAD-dependent epimerase/dehydratase K01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]
D SiH_0093 bifunctional phosphoglucose/phosphomannose isomerase K15916 pgi-pmi; glucose/mannose-6-phosphate isomerase [EC:5.3.1.9 5.3.1.8]
D SiH_1760 Nucleotidyl transferase K00966 GMPP; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]
C 00620 Pyruvate metabolism [PATH:sih00620]
D SiH_0033 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0576 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0727 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0496 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_2388 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0614 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0624 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0646 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_2425 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SiH_2424 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SiH_0582 dehydrogenase complex, dihydrolipoamide acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0994 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0298 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_1187 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SiH_1278 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D SiH_0681 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D SiH_2150 FAD linked oxidase domain protein K00102 LDHD; D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4]
D SiH_2382 Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D SiH_2685 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SiH_1107 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D SiH_0069 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SiH_0993 Phosphoenolpyruvate carboxykinase (GTP) K01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]
D SiH_1281 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D SiH_0492 malate synthase K01638 aceB; malate synthase [EC:2.3.3.9]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0206 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D SiH_1944 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D SiH_1190 transcriptional regulator, AsnC family K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:sih00630]
D SiH_0491 isocitrate lyase K01637 E4.1.3.1; isocitrate lyase [EC:4.1.3.1]
D SiH_0033 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0576 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0727 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0496 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_2388 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0614 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0624 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0646 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0492 malate synthase K01638 aceB; malate synthase [EC:2.3.3.9]
D SiH_2685 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SiH_2681 2-methylcitrate synthase/citrate synthase II K01647 CS; citrate synthase [EC:2.3.3.1]
D SiH_1092 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1038 MaoC domain protein dehydratase K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D SiH_0222 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SiH_0261 Carbamoyl-phosphate synthase L chain ATP-binding protein K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
D SiH_0259 carboxyl transferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D SiH_0260 biotin/lipoyl attachment domain-containing protein K15037 K15037; biotin carboxyl carrier protein
D SiH_0076 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D SiH_0221 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D SiH_0416 FAD linked oxidase domain protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D SiH_2151 FAD linked oxidase domain protein K00104 glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14]
D SiH_1976 SPP-like hydrolase K22223 pgp; phosphoglycolate phosphatase [EC:3.1.3.18]
D SiH_0238 glutamine synthetase catalytic region K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1713 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_2707 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1550 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SiH_1248 glycine dehydrogenase (decarboxylating) K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D SiH_1249 glycine dehydrogenase (decarboxylating) K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D SiH_1247 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1246 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D SiH_1119 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein
D SiH_1083 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein
D SiH_1407 Hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SiH_1153 formate dehydrogenase, alpha subunit K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D SiH_2417 formate dehydrogenase, alpha subunit K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D SiH_0580 cyclase family protein K07130 kynB; arylformamidase [EC:3.5.1.9]
D SiH_2232 cyclase family protein K07130 kynB; arylformamidase [EC:3.5.1.9]
D SiH_0975 predicted acetamidase/formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
C 00640 Propanoate metabolism [PATH:sih00640]
D SiH_0033 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0576 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0727 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0496 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_2388 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0614 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0624 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0646 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0681 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_0261 Carbamoyl-phosphate synthase L chain ATP-binding protein K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
D SiH_0259 carboxyl transferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D SiH_0260 biotin/lipoyl attachment domain-containing protein K15037 K15037; biotin carboxyl carrier protein
D SiH_2095 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D SiH_0222 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SiH_0076 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D SiH_0221 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D SiH_0282 Succinate--CoA ligase (ADP-forming) K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SiH_0281 ATP-citrate lyase/succinyl-CoA ligase K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SiH_2684 2-methylcitrate dehydratase K01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79]
D SiH_2683 methylisocitrate lyase K03417 prpB; methylisocitrate lyase [EC:4.1.3.30]
C 00650 Butanoate metabolism [PATH:sih00650]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_1038 MaoC domain protein dehydratase K17865 croR; 3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
D SiH_1102 coenzyme A transferase K01039 gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12]
D SiH_1101 coenzyme A transferase K01040 gctB; glutaconate CoA-transferase, subunit B [EC:2.8.3.12]
D SiH_0159 succinate dehydrogenase or fumarate reductase,flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SiH_0160 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SiH_0161 CoB-CoM heterodisulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SiH_0162 succinate dehydrogenase subunit D (SdhD) K18859 sdhD; succinate dehydrogenase subunit D
D SiH_2095 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D SiH_2522 Vinylacetyl-CoA Delta-isomerase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
D SiH_0300 Vinylacetyl-CoA Delta-isomerase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_2425 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SiH_2424 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SiH_1554 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D SiH_1519 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_0433 thiamine pyrophosphate protein central region K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_2096 thiamine pyrophosphate protein TPP binding domain protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_2541 Alcohol dehydrogenase GroES domain protein K00004 BDH; (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303]
C 00660 C5-Branched dibasic acid metabolism [PATH:sih00660]
D SiH_1519 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_0433 thiamine pyrophosphate protein central region K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_2096 thiamine pyrophosphate protein TPP binding domain protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_0282 Succinate--CoA ligase (ADP-forming) K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SiH_0281 ATP-citrate lyase/succinyl-CoA ligase K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SiH_0266 3-isopropylmalate dehydratase K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SiH_0265 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SiH_1363 isopropylmalate/isohomocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
C 00562 Inositol phosphate metabolism [PATH:sih00562]
D SiH_0216 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D SiH_1279 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D SiH_1746 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D SiH_2678 Triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:sih00190]
D SiH_1755 NADH-ubiquinone/plastoquinone oxidoreductase chain 3 K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D SiH_1406 NADH-quinone oxidoreductase, B subunit K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D SiH_1754 NADH (or F420H2) dehydrogenase, subunit C K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D SiH_1753 NADH dehydrogenase (quinone) K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D SiH_1752 NADH dehydrogenase (quinone) K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D SiH_1751 NADH-quinone oxidoreductase, chain I K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D SiH_1750 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D SiH_1749 NADH-ubiquinone oxidoreductase chain 4L K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D SiH_1748 NADH dehydrogenase (quinone) K15863 nuoLM; NADH-quinone oxidoreductase subunit L/M [EC:7.1.1.2]
D SiH_1747 NADH/Ubiquinone/plastoquinone (complex I) K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D SiH_1166 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D SiH_2162 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]
D SiH_0159 succinate dehydrogenase or fumarate reductase,flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SiH_0160 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SiH_0161 CoB-CoM heterodisulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SiH_0162 succinate dehydrogenase subunit D (SdhD) K18859 sdhD; succinate dehydrogenase subunit D
D SiH_1446 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D SiH_2324 cytochrome c oxidase subunit II K02826 qoxA; cytochrome aa3-600 menaquinol oxidase subunit II [EC:7.1.1.5]
D SiH_2611 Cytochrome b/b6 domain protein K24008 soxC; cytochrome aa3-type oxidase subunit III
D SiH_2610 cytochrome c oxidase subunit I K24009 soxB; cytochrome aa3-type oxidase subunit I [EC:7.1.1.4]
D SiH_2609 cytochrome c oxidase subunit II K24010 soxA; cytochrome aa3-type oxidase subunit II [EC:7.1.1.4]
D SiH_2320 Cytochrome-c oxidase K24011 soxM; cytochrome aa3-type oxidase subunit I/III [EC:7.1.1.4]
D SiH_1532 ATP synthase, A subunit K02117 ATPVA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]
D SiH_1531 ATP synthase, B subunit K02118 ATPVB; V/A-type H+/Na+-transporting ATPase subunit B
D SiH_1530 V-type ATPase, D subunit K02120 ATPVD; V/A-type H+/Na+-transporting ATPase subunit D
D SiH_1533 H+transporting two-sector ATPase E subunit K02121 ATPVE; V/A-type H+/Na+-transporting ATPase subunit E
D SiH_1534 Vacuolar H+transporting two-sector ATPase Fsubunit K02122 ATPVF; V/A-type H+/Na+-transporting ATPase subunit F
D SiH_1535 V-type ATPase 116 kDa subunit K02123 ATPVI; V/A-type H+/Na+-transporting ATPase subunit I
D SiH_1528 H+transporting two-sector ATPase C subunit K02124 ATPVK; V/A-type H+/Na+-transporting ATPase subunit K
D SiH_0189 Inorganic diphosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation in photosynthetic organisms
C 00720 Carbon fixation pathways in prokaryotes [PATH:sih00720]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_1281 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D SiH_0069 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SiH_2685 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SiH_1107 fumarate lyase K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D SiH_0159 succinate dehydrogenase or fumarate reductase,flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D SiH_0160 succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D SiH_0161 CoB-CoM heterodisulfide reductase K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D SiH_0162 succinate dehydrogenase subunit D (SdhD) K18859 sdhD; succinate dehydrogenase subunit D
D SiH_0281 ATP-citrate lyase/succinyl-CoA ligase K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D SiH_0282 Succinate--CoA ligase (ADP-forming) K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D SiH_0568 Aldehyde Dehydrogenase K15038 K15038; succinyl-CoA reductase [EC:1.2.1.76]
D SiH_1606 alcohol dehydrogenase, zinc-binding domain K14465 K14465; succinate semialdehyde reductase (NADPH) [EC:1.1.1.-]
D SiH_0833 medium-chain-fatty-acid--CoA ligase (AlkK-1) K18861 K18861; 4-hydroxybutyrate---CoA ligase (AMP-forming) [EC:6.2.1.40]
D SiH_2522 Vinylacetyl-CoA Delta-isomerase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
D SiH_0300 Vinylacetyl-CoA Delta-isomerase K14534 abfD; 4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase [EC:4.2.1.120 5.3.3.3]
D SiH_0309 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D SiH_2380 3-hydroxybutyryl-CoA dehydrogenase K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D SiH_2299 3-hydroxybutyryl-CoA dehydrogenase K15016 K15016; enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.35]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2425 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00174 korA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]
D SiH_2424 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit K00175 korB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]
D SiH_2759 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D SiH_1092 aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D SiH_0261 Carbamoyl-phosphate synthase L chain ATP-binding protein K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
D SiH_0259 carboxyl transferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D SiH_0260 biotin/lipoyl attachment domain-containing protein K15037 K15037; biotin carboxyl carrier protein
D SiH_2755 aspartate-semialdehyde dehydrogenase K15017 K15017; malonyl-CoA/succinyl-CoA reductase (NADPH) [EC:1.2.1.75 1.2.1.76]
D SiH_1456 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein K15039 K15039; 3-hydroxypropionate dehydrogenase (NADP+) [EC:1.1.1.298]
D SiH_2103 AMP-dependent synthetase and ligase K15018 K15018; 3-hydroxypropionyl-coenzyme A synthetase [EC:6.2.1.36]
D SiH_1448 Enoyl-CoA hydratase/isomerase K15019 K15019; 3-hydroxypropionyl-coenzyme A dehydratase [EC:4.2.1.116]
D SiH_1323 alcohol dehydrogenase GroES domain protein K15020 K15020; acryloyl-coenzyme A reductase [EC:1.3.1.84]
D SiH_0293 Alcohol dehydrogenase GroES domain protein K15020 K15020; acryloyl-coenzyme A reductase [EC:1.3.1.84]
D SiH_0222 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SiH_0221 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D SiH_0076 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D SiH_0033 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0576 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0727 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0496 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_2388 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0614 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0624 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0646 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
C 00680 Methane metabolism [PATH:sih00680]
D SiH_1153 formate dehydrogenase, alpha subunit K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D SiH_2417 formate dehydrogenase, alpha subunit K00123 fdoG; formate dehydrogenase major subunit [EC:1.17.1.9]
D SiH_1550 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SiH_1407 Hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SiH_1253 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SiH_0069 phosphoenolpyruvate carboxylase K01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]
D SiH_2685 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SiH_2084 Fructose-bisphosphate aldolase K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D SiH_1791 conserved hypothetical protein K01622 K01622; fructose 1,6-bisphosphate aldolase/phosphatase [EC:4.1.2.13 3.1.3.11]
D SiH_1931 6-phospho 3-hexuloisomerase K08094 hxlB; 6-phospho-3-hexuloisomerase [EC:5.3.1.27]
D SiH_1876 Orotidine 5'-phosphate decarboxylase K08093 hxlA; 3-hexulose-6-phosphate synthase [EC:4.1.2.43]
D SiH_1060 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K03388 hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D SiH_1057 CoB--CoM heterodisulfide reductase K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D SiH_1061 conserved hypothetical protein K03389 hdrB2; heterodisulfide reductase subunit B2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D SiH_1058 heterodisulfide reductase subunit C (HdrC-2) K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D SiH_1062 heterodisulfide reductase, subunit C (HdrC-1) K03390 hdrC2; heterodisulfide reductase subunit C2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6]
D SiH_0033 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0576 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0727 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0496 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_2388 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0614 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0624 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0646 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_1281 phosphoenolpyruvate synthase K01007 pps; pyruvate, water dikinase [EC:2.7.9.2]
D SiH_0053 phosphoglycerate mutase K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SiH_1662 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D SiH_1261 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00910 Nitrogen metabolism [PATH:sih00910]
D SiH_0975 predicted acetamidase/formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
D SiH_0816 Nitric oxide reductase large subunit-like protein K04561 norB; nitric oxide reductase subunit B [EC:1.7.2.5]
D SiH_0598 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_0642 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_0238 glutamine synthetase catalytic region K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1713 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_2707 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism [PATH:sih00920]
D SiH_2360 sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D SiH_2361 adenylylsulfate reductase, thioredoxin dependent K00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]
D SiH_0072 FAD-dependent pyridine nucleotide-disulphideoxido reductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D SiH_2635 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D SiH_2366 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 sqr; sulfide:quinone oxidoreductase [EC:1.8.5.4]
D SiH_0821 molybdopterin oxidoreductase Fe4S4 region K17219 sreA; sulfur reductase molybdopterin subunit
D SiH_0820 4Fe-4S ferredoxin iron-sulfur binding domain protein K17220 sreB; sulfur reductase FeS subunit
D SiH_0819 Polysulphide reductase NrfD K17221 sreC; sulfur reductase membrane anchor
D SiH_0690 TQO small subunit DoxA domain protein K16936 doxA; thiosulfate dehydrogenase (quinone) small subunit [EC:1.8.5.2]
D SiH_0689 TQO small subunit DoxD K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D SiH_2212 TQO small subunit DoxD K16937 doxD; thiosulfate dehydrogenase (quinone) large subunit [EC:1.8.5.2]
D SiH_2364 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SiH_1163 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SiH_0171 Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D SiH_2390 selenium-binding protein K17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4]
D SiH_0429 Rieske (2Fe-2S) domain protein K15762 tmoC; toluene monooxygenase system ferredoxin subunit
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:sih00061]
D SiH_0087 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0101 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_2193 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_1194 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0297 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_2238 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_1710 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation [PATH:sih00071]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0294 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_2165 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SiH_2238 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_1710 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_0424 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D SiH_0336 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D SiH_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0994 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0298 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:sih00561]
D SiH_1407 Hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SiH_0838 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D SiH_0188 glycosyl transferase family 2 K19003 mgdA; 1,2-diacylglycerol 3-beta-glucosyltransferase [EC:2.4.1.336]
D SiH_2686 NAD-dependent epimerase/dehydratase K06118 SQD1; UDP-sulfoquinovose synthase [EC:3.13.1.1]
C 00564 Glycerophospholipid metabolism [PATH:sih00564]
D SiH_0320 FAD dependent oxidoreductase K00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]
D SiH_2622 conserved hypothetical protein K00113 glpC; glycerol-3-phosphate dehydrogenase subunit C
D SiH_1327 3-dehydroquinate synthase K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
D SiH_1816 geranylgeranylglyceryl phosphate synthase K17104 E2.5.1.41; phosphoglycerol geranylgeranyltransferase [EC:2.5.1.41]
D SiH_1515 UbiA prenyltransferase K17105 E2.5.1.42; geranylgeranylglycerol-phosphate geranylgeranyltransferase [EC:2.5.1.42]
D SiH_1309 conserved hypothetical protein K19664 carS; CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase [EC:2.7.7.67]
D SiH_0155 geranylgeranyl reductase K17830 GGR; digeranylgeranylglycerophospholipid reductase [EC:1.3.1.101 1.3.7.11]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
D SiH_2277 glycoside hydrolase family 1 K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism [PATH:sih00592]
D SiH_0294 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:sih00230]
D SiH_2742 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_1136 ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D SiH_1467 Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SiH_1468 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SiH_1466 phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D SiH_2035 phosphoribosylaminoimidazole carboxylase K08289 purT; phosphoribosylglycinamide formyltransferase 2 [EC:6.3.1.21]
D SiH_1469 phosphoribosylformylglycinamidine synthase II K23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]
D SiH_1471 phosphoribosylformylglycinamidine synthase, purS K23264 purS; phosphoribosylformylglycinamidine synthase subunit PurS [EC:6.3.5.3]
D SiH_1470 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SiH_1465 phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D SiH_1114 phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D SiH_1115 phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D SiH_1472 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D SiH_1835 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D SiH_1834 IMP biosynthesis enzyme PurP domain protein K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D SiH_1836 IMP biosynthesis enzyme PurP domain protein K06863 purP; 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [EC:6.3.4.23]
D SiH_1845 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D SiH_0048 inosine/xanthosine triphosphatase K01529 yjjX; inosine/xanthosine triphosphatase [EC:3.6.1.73]
D SiH_1650 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family K01519 rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]
D SiH_0246 GMP synthase, small subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SiH_2080 GMP synthase domain protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SiH_1238 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SiH_0296 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SiH_0370 Ppx/GppA phosphatase K01524 ppx-gppA; exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]
D SiH_1824 adenylyl cyclase CyaB K05873 cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]
D SiH_1833 Adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D SiH_1390 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D SiH_1618 nucleotide kinase-like protein K18532 AK6; adenylate kinase [EC:2.7.4.3]
D SiH_2746 conserved hypothetical protein K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
D SiH_1828 histidine triad (HIT) protein K19710 E2.7.7.53; ATP adenylyltransferase [EC:2.7.7.53]
D SiH_2360 sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D SiH_0979 urease subunit alpha K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D SiH_0978 bifunctional urease subunit gamma/beta K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5]
C 00240 Pyrimidine metabolism [PATH:sih00240]
D SiH_1459 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SiH_1460 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SiH_1484 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D SiH_1485 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D SiH_1487 amidohydrolase K01465 URA4; dihydroorotase [EC:3.5.2.3]
D SiH_1488 dihydroorotate dehydrogenase family protein K00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]
D SiH_1483 orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D SiH_1482 orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D SiH_1192 uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D SiH_1845 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D SiH_1877 CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D SiH_1393 cytidylate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D SiH_1842 uracil phosphoribosyltransferase K00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]
D SiH_2490 Amidohydrolase 3 K01485 codA; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D SiH_1889 deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D SiH_2338 deoxycytidine triphosphate deaminase (dcD-2) K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D SiH_1238 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SiH_0296 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SiH_0368 thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D SiH_0369 dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D SiH_1305 dTMP kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D SiH_1756 thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D SiH_2538 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:sih00250]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_1172 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D SiH_0151 peptidase T2 asparaginase 2 K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D SiH_2031 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase K13566 NIT2; omega-amidase [EC:3.5.1.3]
D SiH_1462 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D SiH_1461 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D SiH_1833 Adenylosuccinate synthase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D SiH_1835 adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D SiH_1484 aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D SiH_1485 aspartate carbamoyltransferase, regulatory subunit K00610 pyrI; aspartate carbamoyltransferase regulatory subunit
D SiH_2095 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D SiH_0598 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_0642 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_0990 Aldehyde Dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D SiH_0238 glutamine synthetase catalytic region K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1713 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_2707 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1459 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SiH_1460 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SiH_1470 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SiH_1699 glucosamine-fructose-6-phosphateamino transferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SiH_0946 glutamine amidotransferase class-II K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SiH_1467 Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SiH_1468 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:sih00260]
D SiH_1286 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SiH_1287 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SiH_1445 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D SiH_0170 homoserine kinase K00872 thrB; homoserine kinase [EC:2.7.1.39]
D SiH_1591 Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 thrC; threonine synthase [EC:4.2.3.1]
D SiH_1285 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D SiH_1550 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SiH_1407 Hydroxypyruvate reductase K11529 gck; glycerate 2-kinase [EC:2.7.1.165]
D SiH_0053 phosphoglycerate mutase K15634 gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]
D SiH_1662 phosphonopyruvate decarboxylase-related protein K15635 apgM; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D SiH_1261 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D SiH_2646 Amine oxidase (copper-containing) K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
D SiH_1248 glycine dehydrogenase (decarboxylating) K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D SiH_1249 glycine dehydrogenase (decarboxylating) K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D SiH_1247 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1246 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D SiH_1119 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein
D SiH_1083 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein
D SiH_1829 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D SiH_1276 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D SiH_1277 pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D SiH_1048 pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
C 00270 Cysteine and methionine metabolism [PATH:sih00270]
D SiH_1671 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D SiH_1672 Cobalamin-independent synthase MetE domain protein K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D SiH_1880 Methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D SiH_1555 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D SiH_1512 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D SiH_1331 Spermine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D SiH_0144 methylthioadenosine phosphorylase K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
D SiH_2551 purine or other phosphorylase family 1 K00772 mtaP; 5'-methylthioadenosine phosphorylase [EC:2.4.2.28]
D SiH_1419 amidohydrolase K12960 mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]
D SiH_1811 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SiH_1332 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D SiH_1286 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SiH_1287 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SiH_1445 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D SiH_0171 Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_2364 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SiH_1163 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SiH_2685 Lactate/malate dehydrogenase K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D SiH_0940 SAF domain protein K16845 suyA; (2R)-sulfolactate sulfo-lyase subunit alpha [EC:4.4.1.24]
D SiH_0939 D-galactarate dehydratase/Altronate hydrolase domain protein K16846 suyB; (2R)-sulfolactate sulfo-lyase subunit beta [EC:4.4.1.24]
D SiH_1261 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
C 00280 Valine, leucine and isoleucine degradation [PATH:sih00280]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_0373 pyruvate flavodoxin/ferredoxin oxidoreductase, alpha subunit K00186 vorA; 2-oxoisovalerate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.7]
D SiH_2165 acyl-CoA dehydrogenase domain protein K00249 ACADM; acyl-CoA dehydrogenase [EC:1.3.8.7]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_0294 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D SiH_0261 Carbamoyl-phosphate synthase L chain ATP-binding protein K01964 K01964; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3]
D SiH_0259 carboxyl transferase K15036 K15036; acetyl-CoA/propionyl-CoA carboxylase [EC:6.4.1.2 6.4.1.3 2.1.3.15]
D SiH_0260 biotin/lipoyl attachment domain-containing protein K15037 K15037; biotin carboxyl carrier protein
D SiH_0222 methylmalonyl-CoA epimerase K05606 MCEE; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1]
D SiH_0076 cobalamin B12-binding domain protein K01849 E5.4.99.2B; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2]
D SiH_0221 methylmalonyl-CoA mutase, large subunit K01848 E5.4.99.2A; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2]
D SiH_0872 6-phosphogluconate dehydrogenase NAD-binding protein K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D SiH_1195 3-hydroxyisobutyrate dehydrogenase K00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1554 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
C 00290 Valine, leucine and isoleucine biosynthesis [PATH:sih00290]
D SiH_1829 threonine dehydratase K01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]
D SiH_0266 3-isopropylmalate dehydratase K01703 leuC; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
D SiH_0265 3-isopropylmalate dehydratase, small subunit K01704 leuD; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]
D SiH_1363 isopropylmalate/isohomocitrate dehydrogenase K00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]
D SiH_1519 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_0433 thiamine pyrophosphate protein central region K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_2096 thiamine pyrophosphate protein TPP binding domain protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_0593 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D SiH_1521 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D SiH_2201 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D SiH_0206 isopropylmalate/citramalate/homocitrate synthase K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D SiH_1944 2-isopropylmalate synthase/homocitrate synthase family protein K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
D SiH_1190 transcriptional regulator, AsnC family K01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]
C 00300 Lysine biosynthesis [PATH:sih00300]
D SiH_1445 Homoserine dehydrogenase K00003 hom; homoserine dehydrogenase [EC:1.1.1.3]
D SiH_1286 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SiH_1287 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SiH_0085 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D SiH_2231 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D SiH_2261 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D SiH_0511 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D SiH_0785 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D SiH_1966 putative transcriptional regulator, GntR family K05825 LYSN; 2-aminoadipate transaminase [EC:2.6.1.-]
D SiH_1925 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D SiH_1924 lysine biosynthesis enzyme LysX K05827 lysX; [lysine-biosynthesis-protein LysW]---L-2-aminoadipate ligase [EC:6.3.2.43]
D SiH_1927 acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D SiH_1928 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D SiH_1923 acetylornithine and succinylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D SiH_1922 N-acetyl-ornithine/N-acetyl-lysine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00310 Lysine degradation [PATH:sih00310]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00220 Arginine biosynthesis [PATH:sih00220]
D SiH_1290 ornithine carbamoyltransferase K00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]
D SiH_1462 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D SiH_1461 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D SiH_0979 urease subunit alpha K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D SiH_0978 bifunctional urease subunit gamma/beta K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5]
D SiH_1046 amidinotransferase K01478 arcA; arginine deiminase [EC:3.5.3.6]
D SiH_1470 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SiH_0238 glutamine synthetase catalytic region K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1713 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_2707 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1459 carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D SiH_1460 carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D SiH_0598 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_0642 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_1925 lysine biosynthesis protein LysW K05826 lysW; alpha-aminoadipate/glutamate carrier protein LysW
D SiH_1458 lysine biosynthesis enzyme LysX K19412 argX; glutamate---[amino group carrier protein] ligase [EC:6.3.2.60]
D SiH_1927 acetylglutamate kinase K05828 lysZ; [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase [EC:2.7.2.17 2.7.2.19]
D SiH_1928 N-acetyl-gamma-glutamyl-phosphate reductase K05829 lysY; [amino group carrier protein]-6-phospho-L-2-aminoadipate/5-phospho-L-glutamate reductase [EC:1.2.1.103 1.2.1.106]
D SiH_1923 acetylornithine and succinylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D SiH_1922 N-acetyl-ornithine/N-acetyl-lysine deacetylase K05831 lysK; [amino group carrier protein]-lysine/ornithine hydrolase [EC:3.5.1.130 3.5.1.132]
C 00330 Arginine and proline metabolism [PATH:sih00330]
D SiH_2408 Creatininase K01470 E3.5.2.10; creatinine amidohydrolase [EC:3.5.2.10]
D SiH_2490 Amidohydrolase 3 K01485 codA; cytosine/creatinine deaminase [EC:3.5.4.1 3.5.4.21]
D SiH_0802 5-oxoprolinase (ATP-hydrolyzing) K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D SiH_2352 5-oxoprolinase (ATP-hydrolyzing) K01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]
D SiH_0803 5-oxoprolinase (ATP-hydrolyzing) K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D SiH_2354 5-oxoprolinase (ATP-hydrolyzing) K01474 hyuB; N-methylhydantoinase B [EC:3.5.2.14]
D SiH_1636 agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D SiH_2529 agmatinase K01480 speB; agmatinase [EC:3.5.3.11]
D SiH_1331 Spermine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
D SiH_1555 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D SiH_1512 S-adenosylmethionine decarboxylase proenzyme K01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]
D SiH_0352 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SiH_1589 pyrroline-5-carboxylate reductase K00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]
D SiH_0990 Aldehyde Dehydrogenase K00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]
D SiH_2190 proline-specific peptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism [PATH:sih00340]
D SiH_1505 ATP phosphoribosyltransferase K00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]
D SiH_1500 phosphoribosyl-ATP diphosphatase K01523 hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]
D SiH_1498 Phosphoribosyl-AMP cyclohydrolase K01496 hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]
D SiH_1504 histidine biosynthesis protein K01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]
D SiH_1499 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit K02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]
D SiH_1502 imidazoleglycerol phosphate synthase, cyclase subunit K02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]
D SiH_1631 aminotransferase class I and II K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1506 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1501 Histidinol dehydrogenase K00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]
C 00350 Tyrosine metabolism [PATH:sih00350]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_1631 aminotransferase class I and II K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1506 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_0767 homogentisate 12-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]
D SiH_2646 Amine oxidase (copper-containing) K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
D SiH_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0994 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0298 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0629 4-hydroxyphenylacetate 3-hydroxylase K00483 hpaB; 4-hydroxyphenylacetate 3-monooxygenase [EC:1.14.14.9]
C 00360 Phenylalanine metabolism [PATH:sih00360]
D SiH_2646 Amine oxidase (copper-containing) K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
D SiH_2638 phenylacetate-CoA ligase K01912 paaK; phenylacetate-CoA ligase [EC:6.2.1.30]
D SiH_2643 thioesterase superfamily protein K02614 paaI; acyl-CoA thioesterase [EC:3.1.2.-]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_1631 aminotransferase class I and II K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1506 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_0352 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SiH_0424 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
D SiH_0336 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00529 hcaD; 3-phenylpropionate/trans-cinnamate dioxygenase ferredoxin reductase component [EC:1.18.1.3]
C 00380 Tryptophan metabolism [PATH:sih00380]
D SiH_0580 cyclase family protein K07130 kynB; arylformamidase [EC:3.5.1.9]
D SiH_2232 cyclase family protein K07130 kynB; arylformamidase [EC:3.5.1.9]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0352 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:sih00400]
D SiH_1774 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]
D SiH_1773 3-dehydroquinate synthase K01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]
D SiH_1768 3-dehydroquinate dehydratase, putative (AroD) K03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]
D SiH_1770 shikimate kinase K00891 aroK; shikimate kinase [EC:2.7.1.71]
D SiH_1769 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D SiH_1771 Chorismate synthase K01736 aroC; chorismate synthase [EC:4.2.3.5]
D SiH_1273 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D SiH_1272 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D SiH_1275 anthranilate phosphoribosyltransferase K00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]
D SiH_1274 N-(5'phosphoribosyl)anthranilate isomerase (PRAI) K01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]
D SiH_1271 Indole-3-glycerol-phosphate synthase K01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]
D SiH_1276 tryptophan synthase, alpha subunit K01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]
D SiH_1277 pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D SiH_1048 pyridoxal-phosphate dependent TrpB-like enzyme K06001 trpB; tryptophan synthase beta chain [EC:4.2.1.20]
D SiH_1775 chorismate mutase K14187 tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12]
D SiH_1830 Prephenate dehydratase K04518 pheA2; prephenate dehydratase [EC:4.2.1.51]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_1631 aminotransferase class I and II K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1506 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism [PATH:sih00410]
D SiH_2095 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D SiH_0735 aminotransferase K15372 toa; taurine---2-oxoglutarate transaminase [EC:2.6.1.55]
D SiH_2537 aminotransferase class-III K15372 toa; taurine---2-oxoglutarate transaminase [EC:2.6.1.55]
D SiH_2646 Amine oxidase (copper-containing) K00276 AOC3; primary-amine oxidase [EC:1.4.3.21]
D SiH_0196 Protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D SiH_2538 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
C 00430 Taurine and hypotaurine metabolism [PATH:sih00430]
D SiH_2089 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SiH_0735 aminotransferase K15372 toa; taurine---2-oxoglutarate transaminase [EC:2.6.1.55]
D SiH_2537 aminotransferase class-III K15372 toa; taurine---2-oxoglutarate transaminase [EC:2.6.1.55]
C 00440 Phosphonate and phosphinate metabolism
C 00450 Selenocompound metabolism [PATH:sih00450]
D SiH_0171 Cystathionine gamma-synthase K01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]
D SiH_1671 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D SiH_1672 Cobalamin-independent synthase MetE domain protein K00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]
D SiH_0032 aminotransferase class V K11717 sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]
D SiH_0215 thioredoxin reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D SiH_2495 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D SiH_2360 sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D SiH_1536 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism [PATH:sih00460]
D SiH_2089 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SiH_0151 peptidase T2 asparaginase 2 K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D SiH_1550 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SiH_0975 predicted acetamidase/formamidase K01455 E3.5.1.49; formamidase [EC:3.5.1.49]
C 00470 D-Amino acid metabolism [PATH:sih00470]
D SiH_1470 phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D SiH_2189 Aldehyde Dehydrogenase K19588 dopDH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
C 00480 Glutathione metabolism [PATH:sih00480]
D SiH_2089 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SiH_2759 isocitrate dehydrogenase, NADP-dependent K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D SiH_1331 Spermine synthase K00797 speE; spermidine synthase [EC:2.5.1.16]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation [PATH:sih00511]
D SiH_2277 glycoside hydrolase family 1 K01190 lacZ; beta-galactosidase [EC:3.2.1.23]
D SiH_2291 glycosyl hydrolase 38 domain protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D SiH_2241 Alpha-L-fucosidase K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis
C 00552 Teichoic acid biosynthesis [PATH:sih00552]
D SiH_0693 hypothetical protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SiH_0695 hypothetical protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:sih00730]
D SiH_0191 phosphomethylpyrimidine kinase K21219 thiDN; hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]
D SiH_1745 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D SiH_1645 thiazole biosynthesis enzyme K22699 thi4; sulfide-dependent adenosine diphosphate thiazole synthase [EC:2.4.2.59]
D SiH_2021 phosphomethylpyrimidine kinase K21220 thiN; thiamine-phosphate diphosphorylase [EC:2.5.1.3]
D SiH_1837 thiamine monophosphate kinase, putative (ThiL) K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D SiH_2746 conserved hypothetical protein K06928 NTPCR; nucleoside-triphosphatase [EC:3.6.1.15]
D SiH_1390 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D SiH_2671 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D SiH_0023 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
C 00740 Riboflavin metabolism [PATH:sih00740]
D SiH_1679 GTP cyclohydrolase IIa K08096 gch3; GTP cyclohydrolase IIa [EC:3.5.4.29]
D SiH_0852 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino) pyrimidine1-reductase K14654 RIB7; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase [EC:1.1.1.302]
D SiH_1676 34-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D SiH_1678 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D SiH_1677 riboflavin synthase K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D SiH_1216 conserved hypothetical protein K07732 rfk; riboflavin kinase, archaea type [EC:2.7.1.161]
D SiH_1217 cytidyltransferase-related domain protein K14656 ribL; FAD synthetase [EC:2.7.7.2]
D SiH_2702 cob(II)yrinic acid a,c-diamide reductase K04719 bluB; 5,6-dimethylbenzimidazole synthase [EC:1.13.11.79]
D SiH_2742 NUDIX hydrolase K01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]
D SiH_1643 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:sih00750]
D SiH_1591 Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 thrC; threonine synthase [EC:4.2.3.1]
D SiH_1285 threonine synthase K01733 thrC; threonine synthase [EC:4.2.3.1]
D SiH_1525 Vitamin B6 biosynthesis protein K06215 pdxS; pyridoxal 5'-phosphate synthase pdxS subunit [EC:4.3.3.6]
D SiH_1524 SNO glutamine amidotransferase K08681 pdxT; pyridoxal 5'-phosphate synthase pdxT subunit [EC:4.3.3.6]
C 00760 Nicotinate and nicotinamide metabolism [PATH:sih00760]
D SiH_1172 L-aspartate oxidase K00278 nadB; L-aspartate oxidase [EC:1.4.3.16]
D SiH_1171 quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D SiH_1175 nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D SiH_1725 Quinolinate phosphoribosyl transferase K00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]
D SiH_1822 nicotinamide-nucleotide adenylyltransferase K00952 nadM; nicotinamide-nucleotide adenylyltransferase [EC:2.7.7.1]
D SiH_2747 NAD+ synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D SiH_0274 Silent information regulator protein Sir2 K12410 cobB; NAD-dependent protein deacetylase/lipoamidase [EC:2.3.1.286 2.3.1.313]
D SiH_0035 NAD(+) kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:sih00770]
D SiH_1519 acetolactate synthase, large subunit, biosynthetic type K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_0433 thiamine pyrophosphate protein central region K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_2096 thiamine pyrophosphate protein TPP binding domain protein K01652 E2.2.1.6L; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]
D SiH_0593 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D SiH_1521 ketol-acid reductoisomerase K00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]
D SiH_2201 dihydroxy-acid dehydratase K01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]
D SiH_0197 3-methyl-2-oxobutanoate hydroxymethyltransferase K00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]
D SiH_0195 GHMP kinase K06982 pok; pantoate kinase [EC:2.7.1.169]
D SiH_0196 Protein of unknown function DUF137 K09722 K09722; 4-phosphopantoate---beta-alanine ligase [EC:6.3.2.36]
D SiH_1864 phosphopantothenoyl cysteine decarboxylase/phosphopantothenate/cysteine ligase K13038 coaBC; phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]
D SiH_1663 Protein of unknown function DUF359 K09735 dpck; GTP-dependent dephospho-CoA kinase [EC:2.7.1.237]
D SiH_2538 amidase, hydantoinase/carbamoylase family K06016 pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]
C 00780 Biotin metabolism [PATH:sih00780]
D SiH_0087 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0101 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_2193 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_1194 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0297 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_1404 biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:sih00785]
D SiH_2154 lipoic acid synthetase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D SiH_1074 radical SAM domain protein K09711 lipS1; lipoyl synthase
D SiH_1073 radical SAM domain protein K24689 lipS2; lipoyl synthase
D SiH_1120 biotin/lipoate A/B protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D SiH_1075 biotin/lipoate A/B protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D SiH_2155 biotin/lipoate A/B protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D SiH_2153 biotin/lipoate A/B protein ligase K03800 lplA; lipoate---protein ligase [EC:6.3.1.20]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_0582 dehydrogenase complex, dihydrolipoamide acyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D SiH_1248 glycine dehydrogenase (decarboxylating) K00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]
D SiH_1249 glycine dehydrogenase (decarboxylating) K00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]
D SiH_1247 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SiH_1246 glycine cleavage system H protein K02437 gcvH; glycine cleavage system H protein
D SiH_1119 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein
D SiH_1083 glycine cleavage H-protein K02437 gcvH; glycine cleavage system H protein
C 00790 Folate biosynthesis [PATH:sih00790]
D SiH_1715 GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D SiH_0005 transcriptional coactivator/pterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D SiH_1475 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D SiH_2586 ExsB family protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D SiH_2046 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D SiH_0207 conserved hypothetical protein K07142 mptE; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D SiH_1709 beta-ribofuranosylaminobenzene 5'-phosphate synthase family K06984 K06984; beta-ribofuranosylaminobenzene 5'-phosphate synthase [EC:2.4.2.54]
D SiH_0147 alpha-L-glutamate ligase, RimK family K15740 mptN; tetrahydromethanopterin:alpha-L-glutamate ligase [EC:6.3.2.33]
D SiH_1717 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D SiH_1317 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D SiH_0192 MoaD family protein K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12]
D SiH_2042 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D SiH_1416 molybdenum cofactor synthesis domain protein K03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]
D SiH_0228 4-diphosphocytidyl-2C-methyl-D-erythritol synthase K07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]
D SiH_1417 molybdopterin-guanine dinucleotide biosynthesisprotein A (MobA) K03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]
C 00670 One carbon pool by folate [PATH:sih00670]
D SiH_1550 Glycine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D SiH_1247 glycine cleavage system T protein K00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]
D SiH_1756 thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D SiH_1622 5-formyltetrahydrofolate cyclo-ligase K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:sih00860]
D SiH_1977 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SiH_1900 glutamyl-tRNA reductase K02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]
D SiH_1898 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
D SiH_1899 porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D SiH_1897 porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D SiH_1896 uroporphyrinogen III synthase HEM4 K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D SiH_0232 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D SiH_2363 uroporphyrin-III C-methyltransferase K02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]
D SiH_1901 siroheme synthase K24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]
D SiH_0566 Radical SAM domain protein K22226 ahbC; Fe-coproporphyrin III synthase
D SiH_0567 Radical SAM domain protein K22227 ahbD; AdoMet-dependent heme synthase [EC:1.3.98.6]
D SiH_1446 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D SiH_1669 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 cbiX; sirohydrochlorin cobaltochelatase [EC:4.99.1.3]
D SiH_0110 precorrin-2 C20-methyltransferase K03394 cobI-cbiL; precorrin-2/cobalt-factor-2 C20-methyltransferase [EC:2.1.1.130 2.1.1.151]
D SiH_0113 precorrin-3B C17-methyltransferase K05934 cobJ; precorrin-3B C17-methyltransferase / cobalt-factor III methyltransferase [EC:2.1.1.131 2.1.1.272]
D SiH_0109 precorrin-4 C11-methyltransferase K05936 cobM; precorrin-4/cobalt-precorrin-4 C11-methyltransferase [EC:2.1.1.133 2.1.1.271]
D SiH_0108 cobalamin (vitamin B12) biosynthesis CbiG protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D SiH_1941 cobalamin (vitamin B12) biosynthesis CbiG protein K02189 cbiG; cobalt-precorrin 5A hydrolase [EC:3.7.1.12]
D SiH_0112 cobalamin biosynthesis protein CbiD K02188 cbiD; cobalt-precorrin-5B (C1)-methyltransferase [EC:2.1.1.195]
D SiH_0111 precorrin-6Y C5,15-methyltransferase(decarboxylating), CbiT subunit K02191 cbiT; cobalt-precorrin-6B (C15)-methyltransferase [EC:2.1.1.196]
D SiH_0107 precorrin-6y C5,15-methyltransferase(decarboxylating), CbiE subunit K03399 cbiE; cobalt-precorrin-7 (C5)-methyltransferase [EC:2.1.1.289]
D SiH_0114 Precorrin-8X methylmutase CbiC/CobH K06042 cobH-cbiC; precorrin-8X/cobalt-precorrin-8 methylmutase [EC:5.4.99.61 5.4.99.60]
D SiH_1674 cobyrinic acid a,c-diamide synthase K02224 cobB-cbiA; cobyrinic acid a,c-diamide synthase [EC:6.3.5.9 6.3.5.11]
D SiH_1703 ATP-cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D SiH_1509 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D SiH_2079 cobyric acid synthase CobQ K02232 cobQ; adenosylcobyric acid synthase [EC:6.3.5.10]
D SiH_2077 cobalamin biosynthesis protein CobD K02227 cbiB; adenosylcobinamide-phosphate synthase [EC:6.3.1.10]
D SiH_0832 conserved hypothetical protein K08260 cbiZ; adenosylcobinamide hydrolase [EC:3.5.1.90]
D SiH_2008 GTP adenosylcobinamide-phosphate guanylyltransferase-like protein K19712 cobY; adenosylcobinamide-phosphate guanylyltransferase [EC:2.7.7.62]
D SiH_2078 cobalamin 5'-phosphate synthase K02233 E2.7.8.26; adenosylcobinamide-GDP ribazoletransferase [EC:2.7.8.26]
D SiH_2259 Beta-glucuronidase K01195 uidA; beta-glucuronidase [EC:3.2.1.31]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:sih00130]
D SiH_1945 4-hydroxybenzoate polyprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D SiH_1284 UbiD family decarboxylase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D SiH_1643 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D SiH_0685 UbiE/COQ5 methyltransferase K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D SiH_2157 flavoprotein WrbA K03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:sih00900]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1554 hydroxymethylglutaryl-CoA synthase K01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]
D SiH_1551 3-hydroxy-3-methylglutaryl Coenzyme A reductase K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34]
D SiH_1698 mevalonate kinase K00869 MVK; mevalonate kinase [EC:2.7.1.36]
D SiH_2305 GHMP kinase K00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2]
D SiH_2304 diphosphomevalonate decarboxylase K01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33]
D SiH_2002 aspartate/glutamate/uridylate kinase K06981 ipk; isopentenyl phosphate kinase [EC:2.7.4.26]
D SiH_1643 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D SiH_2003 isopentenyl-diphosphate delta-isomerase, type 2 K01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]
D SiH_2004 Farnesyltranstransferase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D SiH_0146 Polyprenyl synthetase K21268 gdS-2; hexaprenyl diphosphate synthase [EC:2.5.1.82]
D SiH_1921 undecaprenyl diphosphate synthase K15888 uppS; tritrans,polycis-undecaprenyl-diphosphate synthase [geranylgeranyl-diphosphate specific] [EC:2.5.1.89]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation [PATH:sih00907]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_0294 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D SiH_1776 transketolase, N-terminal subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D SiH_1778 transketolase, C-terminal subunit K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
D SiH_0314 beta-lactamase domain protein K05555 actIV; cyclase [EC:4.-.-.-]
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis [PATH:sih00523]
D SiH_1700 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SiH_0444 glucose-1-phosphate thymidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SiH_1343 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D SiH_0443 NAD-dependent epimerase/dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D SiH_0601 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D SiH_0445 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D SiH_2735 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
D SiH_0443 NAD-dependent epimerase/dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids [PATH:sih00946]
D SiH_2270 alpha-L-rhamnosidase K05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40]
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
D SiH_1007 peptidase S45 penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11]
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis [PATH:sih00261]
D SiH_2360 sulfate adenylyltransferase K00958 sat; sulfate adenylyltransferase [EC:2.7.7.4]
D SiH_1286 aspartate kinase K00928 lysC; aspartate kinase [EC:2.7.2.4]
D SiH_1287 aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D SiH_0085 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D SiH_2231 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
D SiH_2261 dihydrodipicolinate synthetase K01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis [PATH:sih00521]
D SiH_1872 Phosphoglucosamine mutase K15778 pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]
D SiH_1279 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D SiH_1746 Myo-inositol-1-phosphate synthase K01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]
D SiH_0216 inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D SiH_1700 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SiH_0444 glucose-1-phosphate thymidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SiH_1343 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D SiH_0443 NAD-dependent epimerase/dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
D SiH_0601 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]
D SiH_0445 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
D SiH_2735 dTDP-4-dehydrorhamnose reductase K00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis [PATH:sih00525]
D SiH_1700 Nucleotidyl transferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SiH_0444 glucose-1-phosphate thymidyltransferase K00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
D SiH_1343 Nucleotidyl transferase K23144 K23144; UDP-N-acetylglucosamine diphosphorylase / glucose-1-phosphate thymidylyltransferase / UDP-N-acetylgalactosamine diphosphorylase / glucosamine-1-phosphate N-acetyltransferase / galactosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.7.7.24 2.7.7.83 2.3.1.157 2.3.1.276]
D SiH_0443 NAD-dependent epimerase/dehydratase K01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
C 00401 Novobiocin biosynthesis [PATH:sih00401]
D SiH_1775 chorismate mutase K14187 tyrA; chorismate mutase / prephenate dehydrogenase [EC:5.4.99.5 1.3.1.12]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_1631 aminotransferase class I and II K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1506 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
D SiH_1273 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D SiH_1272 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
C 00333 Prodigiosin biosynthesis
D SiH_0087 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0101 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_2193 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_1194 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0297 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
C 00999 Biosynthesis of various plant secondary metabolites
D SiH_1880 Methionine adenosyltransferase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation [PATH:sih00362]
D SiH_1968 alpha/beta hydrolase fold protein K01055 pcaD; 3-oxoadipate enol-lactonase [EC:3.1.1.24]
D SiH_0294 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
D SiH_0289 iron-containing alcohol dehydrogenase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]
D SiH_2371 Carboxymuconolactone decarboxylase K01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
C 00627 Aminobenzoate degradation [PATH:sih00627]
D SiH_0352 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SiH_1278 acylphosphatase K01512 acyP; acylphosphatase [EC:3.6.1.7]
D SiH_1643 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
C 00364 Fluorobenzoate degradation [PATH:sih00364]
D SiH_0862 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
D SiH_0289 iron-containing alcohol dehydrogenase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]
C 00625 Chloroalkane and chloroalkene degradation [PATH:sih00625]
D SiH_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0994 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0298 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_1029 haloacid dehalogenase, type II K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]
C 00361 Chlorocyclohexane and chlorobenzene degradation [PATH:sih00361]
D SiH_0862 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
D SiH_0289 iron-containing alcohol dehydrogenase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]
D SiH_1029 haloacid dehalogenase, type II K01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]
C 00623 Toluene degradation [PATH:sih00623]
D SiH_0427 YHS domain protein K15760 tmoA; toluene monooxygenase system protein A [EC:1.14.13.236 1.14.13.-]
D SiH_0426 methane/phenol/toluene hydroxylase K15760 tmoA; toluene monooxygenase system protein A [EC:1.14.13.236 1.14.13.-]
D SiH_0429 Rieske (2Fe-2S) domain protein K15762 tmoC; toluene monooxygenase system ferredoxin subunit
D SiH_0430 monooxygenase component MmoB/DmpM K15763 tmoD; toluene monooxygenase system protein D [EC:1.14.13.236 1.14.13.-]
D SiH_0431 methane/phenol/toluene hydroxylase K15764 tmoE; toluene monooxygenase system protein E [EC:1.14.13.236 1.14.13.-]
D SiH_0862 Carboxymethylenebutenolidase K01061 E3.1.1.45; carboxymethylenebutenolidase [EC:3.1.1.45]
D SiH_0289 iron-containing alcohol dehydrogenase K00217 E1.3.1.32; maleylacetate reductase [EC:1.3.1.32]
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation [PATH:sih00633]
D SiH_0892 [NiFe] hydrogenase large subunit, HyaB K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D SiH_0921 Ni Fe-hydrogenase I large subunit-like protein K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D SiH_0891 hydrogenase (NiFe) small subunit HydA K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D SiH_0920 nickel-dependent hydrogenase small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D SiH_0915 coenzyme F420-reducing hydrogenase alpha subunit-like protein K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D SiH_0910 nickel-dependent hydrogenase, large subunit K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D SiH_0909 NADH ubiquinone oxidoreductase, 20 kDa subunit K23548 hupU; uptake hydrogenase small subunit [EC:1.12.99.6]
D SiH_0346 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_2505 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein K00169 porA; pyruvate ferredoxin oxidoreductase alpha subunit [EC:1.2.7.1]
D SiH_0372 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0345 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_2506 thiamine pyrophosphate protein domain protein TPP-binding protein K00170 porB; pyruvate ferredoxin oxidoreductase beta subunit [EC:1.2.7.1]
D SiH_0375 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2503 pyruvate/ketoisovalerate oxidoreductase, gamma subunit K00172 porC; pyruvate ferredoxin oxidoreductase gamma subunit [EC:1.2.7.1]
D SiH_2504 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0347 pyruvate ferredoxin, flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
D SiH_0374 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit K00171 porD; pyruvate ferredoxin oxidoreductase delta subunit [EC:1.2.7.1]
C 00642 Ethylbenzene degradation
D SiH_0294 acetyl-CoA acetyltransferase K00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]
C 00643 Styrene degradation [PATH:sih00643]
D SiH_0767 homogentisate 12-dioxygenase K00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]
D SiH_0352 Amidase K01426 E3.5.1.4; amidase [EC:3.5.1.4]
D SiH_1102 coenzyme A transferase K01039 gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12]
D SiH_1101 coenzyme A transferase K01040 gctB; glutaconate CoA-transferase, subunit B [EC:2.8.3.12]
C 00791 Atrazine degradation
D SiH_0979 urease subunit alpha K01428 ureC; urease subunit alpha [EC:3.5.1.5]
D SiH_0978 bifunctional urease subunit gamma/beta K14048 ureAB; urease subunit gamma/beta [EC:3.5.1.5]
C 00930 Caprolactam degradation
D SiH_2641 enoyl-CoA hydratase/isomerase K01692 paaF; enoyl-CoA hydratase [EC:4.2.1.17]
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation [PATH:sih00626]
D SiH_0730 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0994 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
D SiH_0298 Alcohol dehydrogenase GroES domain protein K13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:sih03020]
D SiH_1848 RNA polymerase Rpb2 domain 6 K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
D SiH_1849 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D SiH_1850 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D SiH_1994 RNA polymerase, subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D SiH_1785 RNA polymerase dimerization K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D SiH_1665 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D SiH_1801 DNA-directed RNA polymerase, subunit G (RpoG) K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
D SiH_1847 RNA polymerase Rpb5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D SiH_1259 RNA polymerase Rpb6 K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D SiH_1998 RNA polymerase, subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D SiH_1635 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D SiH_1682 conserved hypothetical protein K00960 rpo13; DNA-directed RNA polymerase subunit 13 [EC:2.7.7.6]
C 03022 Basal transcription factors [PATH:sih03022]
D SiH_1633 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D SiH_1226 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D SiH_1220 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D SiH_1810 Transcription factor TFIIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D SiH_1765 XPD repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:sih03010]
D SiH_1999 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D SiH_1372 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D SiH_1992 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D SiH_1386 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D SiH_1855 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D SiH_1381 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D SiH_1997 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D SiH_1857 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D SiH_1993 ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D SiH_1853 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12
D SiH_1991 ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D SiH_1380 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SiH_1670 Ribosomal S13S15 domain protein K02956 RP-S15; small subunit ribosomal protein S15
D SiH_1375 ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D SiH_1370 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D SiH_1342 ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D SiH_1378 Ribosomal protein S4E, central domain protein K02987 RP-S4e; small subunit ribosomal protein S4e
D SiH_1668 Ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D SiH_1920 ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D SiH_1792 ribosomal protein S17E (rps17E) K02962 RP-S17e; small subunit ribosomal protein S17e
D SiH_1726 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D SiH_1646 ribosomal protein S24E (rps24E) K02974 RP-S24e; small subunit ribosomal protein S24e
D SiH_1658 ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e
D SiH_1526 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e
D SiH_1130 Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D SiH_1647 ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D SiH_1843 Ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D SiH_1233 ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e
D SiH_1737 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D SiH_1369 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D SiH_1366 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D SiH_1379 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D SiH_1382 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D SiH_1738 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D SiH_1736 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D SiH_1739 ribosomal protein 60S K02869 RP-L12; large subunit ribosomal protein L12
D SiH_1996 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D SiH_1376 ribosomal protein L14b K02874 RP-L14; large subunit ribosomal protein L14
D SiH_1388 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D SiH_1385 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18
D SiH_1371 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D SiH_1368 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23
D SiH_1377 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D SiH_1373 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D SiH_1387 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30
D SiH_1367 ribosomal protein L4/L1e K02930 RP-L4e; large subunit ribosomal protein L4e
D SiH_1978 ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D SiH_1782 ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D SiH_1685 ribosomal protein L14 K02875 RP-L14e; large subunit ribosomal protein L14e
D SiH_1345 Ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D SiH_1995 ribosomal protein L15 K02883 RP-L18e; large subunit ribosomal protein L18e
D SiH_1384 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D SiH_1336 ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D SiH_1844 Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D SiH_1851 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02908 RP-L30e; large subunit ribosomal protein L30e
D SiH_1729 ribosomal protein L31E (rpl31E) K02910 RP-L31e; large subunit ribosomal protein L31e
D SiH_1383 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D SiH_1392 Ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e
D SiH_1330 Ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D SiH_1354 50S ribosomal protein L37 K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D SiH_1728 Ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D SiH_1911 Ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D SiH_1131 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D SiH_1731 ribosomal LX protein K02944 RP-LX; large subunit ribosomal protein LX
D SiH_r0002 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D SiH_r0001 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D SiH_r0003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:sih00970]
D SiH_t0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SiH_t0033 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SiH_t0027 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SiH_t0008 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0031 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0020 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0030 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0029 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0045 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D SiH_t0037 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D SiH_t0006 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SiH_t0024 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SiH_t0010 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D SiH_t0022 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D SiH_t0019 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SiH_t0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SiH_t0023 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SiH_t0038 tRNA-His K14226 tRNA-His; tRNA His
D SiH_t0003 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D SiH_t0005 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0016 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0001 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0009 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0015 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0040 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SiH_t0041 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SiH_t0014 tRNA-Met K14230 tRNA-Met; tRNA Met
D SiH_t0021 tRNA-Met K14230 tRNA-Met; tRNA Met
D SiH_t0036 tRNA-Met K14230 tRNA-Met; tRNA Met
D SiH_t0017 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D SiH_t0004 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SiH_t0028 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SiH_t0046 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SiH_t0044 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0013 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0025 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0035 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0007 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SiH_t0034 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SiH_t0047 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SiH_t0043 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D SiH_t0012 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D SiH_t0011 tRNA-Val K14237 tRNA-Val; tRNA Val
D SiH_t0032 tRNA-Val K14237 tRNA-Val; tRNA Val
D SiH_t0042 tRNA-Val K14237 tRNA-Val; tRNA Val
D SiH_1977 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SiH_1322 amidase K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SiH_1214 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SiH_1841 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D SiH_1213 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D SiH_1234 glutamyl-tRNA(Gln) amidotransferase, subunit D K09482 gatD; glutamyl-tRNA(Gln) amidotransferase subunit D [EC:6.3.5.7]
D SiH_1235 aspartyl-tRNA(Asn) amidotransferase, B subunit K03330 gatE; glutamyl-tRNA(Gln) amidotransferase subunit E [EC:6.3.5.7]
D SiH_1740 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SiH_0949 alanyl-tRNA synthetase-like protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SiH_1909 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D SiH_1637 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D SiH_0285 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SiH_1496 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SiH_0092 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SiH_1536 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SiH_1268 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SiH_1579 tRNA synthetase valyl/leucyl anticodon-binding protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1508 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1364 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SiH_1979 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D SiH_1302 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SiH_1527 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SiH_1799 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SiH_1970 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SiH_1969 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SiH_1988 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SiH_1626 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:sih03060]
D SiH_1389 SecY protein K03076 secY; preprotein translocase subunit SecY
D SiH_1197 GTP-binding signal recognition particle SRP54, G-domain K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SiH_r0004 7S ribosomal RNA K01983 ffs; SRP RNA
D SiH_1733 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SiH_1919 conserved hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19
D SiH_1597 sec-independent translocation protein mttA/Hcf106 K03116 tatA; sec-independent protein translocase protein TatA
D SiH_1598 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D SiH_2200 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D SiH_1596 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC
D SiH_2199 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
D SiH_1250 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D SiH_0483 membrane protein K13280 SEC11; signal peptidase I [EC:3.4.21.89]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:sih04122]
D SiH_2364 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SiH_1163 Rhodanese domain protein K01011 TST; thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]
D SiH_0674 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D SiH_1063 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D SiH_2217 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D SiH_1717 molybdenum cofactor biosynthesis protein A K03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]
D SiH_0192 MoaD family protein K21142 moaX; MoaE-MoaD fusion protein [EC:2.8.1.12]
D SiH_1777 UBA/THIF-type NAD/FAD binding protein K21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]
D SiH_1317 molybdenum cofactor biosynthesis protein C K03637 moaC; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]
D SiH_2042 molybdenum cofactor synthesis domain protein K03638 moaB; molybdopterin adenylyltransferase [EC:2.7.7.75]
D SiH_1745 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
C 03050 Proteasome [PATH:sih03050]
D SiH_1806 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
D SiH_1349 Proteasome endopeptidase complex K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D SiH_1321 proteasome endopeptidase complex K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D SiH_1800 Proteasome endopeptidase complex K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
C 03018 RNA degradation [PATH:sih03018]
D SiH_1784 RNA binding S1 domain protein K07573 CSL4; exosome complex component CSL4
D SiH_1351 KH type 1 domain protein K03679 RRP4; exosome complex component RRP4
D SiH_1353 3' exoribonuclease K12589 RRP42; exosome complex component RRP42
D SiH_1352 exosome complex exonuclease 1 K11600 RRP41; exosome complex component RRP41
D SiH_1253 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:sih03030]
D SiH_1987 TOPRIM domain protein K02316 dnaG; DNA primase [EC:2.7.7.101]
D SiH_0184 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D SiH_1986 DNA polymerase B exonuclease K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D SiH_0714 DNA polymerase elongation subunit (family B) K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D SiH_1542 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D SiH_1312 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D SiH_1133 DNA primase small subunit, PriSL K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D SiH_1537 DNA primase, large subunit K18882 priL; DNA primase large subunit
D SiH_1134 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1673 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D SiH_1319 Replication factor C K04801 rfcS; replication factor C small subunit
D SiH_1318 AAA ATPase central domain protein K04800 rfcL; replication factor C large subunit
D SiH_1902 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D SiH_1890 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03410 Base excision repair [PATH:sih03410]
D SiH_1956 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SiH_1134 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1673 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D SiH_1902 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D SiH_1890 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D SiH_0086 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SiH_2528 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SiH_0102 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SiH_2730 Xylose isomerase domain protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
C 03420 Nucleotide excision repair [PATH:sih03420]
D SiH_1765 XPD repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D SiH_1358 nucleotide excision repair nuclease, Xpf K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D SiH_1134 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1673 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D SiH_1890 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03430 Mismatch repair [PATH:sih03430]
D SiH_1134 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1673 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D SiH_1890 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
C 03440 Homologous recombination
C 03450 Non-homologous end-joining
D SiH_1902 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1 [PATH:sih03250]
D SiH_1664 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4
D SiH_1735 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5
D SiH_1257 AAA ATPase central domain protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus and Lyssavirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:sih02010]
D SiH_1151 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D SiH_1150 ABC-type sulfate transport system, permease, CysU K15496 wtpB; molybdate/tungstate transport system permease protein
D SiH_1712 ABC transporter related protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D SiH_2545 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D SiH_1024 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D SiH_1021 extracellular solute-binding protein family 1 K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D SiH_1022 ABC-type sugar transport system, permease, UgpA K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SiH_1023 ABC-type maltose transport system, permease, MalG K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SiH_1170 trehalose binding protein K17311 treS; trehalose transport system substrate-binding protein
D SiH_1169 ABC-type sugar transport systems, permease, UgpA K17312 treT; trehalose transport system permease protein
D SiH_1168 ABC-type sugar transport system, permease, UgpE K17313 treU; trehalose transport system permease protein
D SiH_1167 ABC transporter related protein K17314 treV; trehalose transport system ATP-binding protein
D SiH_2399 glucose binding protein K10196 glcS; glucose/arabinose transport system substrate-binding protein
D SiH_2237 arabinose binding protein K10196 glcS; glucose/arabinose transport system substrate-binding protein
D SiH_2398 ABC-type sugar transport system, permease, UgpA K10197 glcT; glucose/arabinose transport system permease protein
D SiH_2236 ABC-type sugar transport systems, permease, UgpA K10197 glcT; glucose/arabinose transport system permease protein
D SiH_2235 ABC-type sugar transport system, permease, UgpE K10198 glcU; glucose/arabinose transport system permease protein
D SiH_2397 ABC-type sugar transport system, permease, UgpE K10198 glcU; glucose/arabinose transport system permease protein
D SiH_2396 ABC transporter related protein K10199 glcV; glucose/arabinose transport system ATP-binding protein
D SiH_2234 ABC transporter related protein K10199 glcV; glucose/arabinose transport system ATP-binding protein
D SiH_1592 ABC transporter related protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SiH_2400 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D SiH_2403 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D SiH_2404 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D SiH_2401 ABC transporter related protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D SiH_2402 ABC transporter related protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D SiH_0655 cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:sih03070]
D SiH_1389 SecY protein K03076 secY; preprotein translocase subunit SecY
D SiH_1733 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SiH_1197 GTP-binding signal recognition particle SRP54, G-domain K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SiH_1597 sec-independent translocation protein mttA/Hcf106 K03116 tatA; sec-independent protein translocase protein TatA
D SiH_1598 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D SiH_2200 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D SiH_1596 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC
D SiH_2199 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:sih02020]
D SiH_0934 Citryl-CoA lyase K01644 citE; citrate lyase subunit beta / citryl-CoA lyase [EC:4.1.3.34]
D SiH_1862 triphosphoribosyl-dephospho-CoA protein K05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]
D SiH_2382 Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) K00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
D SiH_0238 glutamine synthetase catalytic region K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1713 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_2707 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0909 NADH ubiquinone oxidoreductase, 20 kDa subunit K23548 hupU; uptake hydrogenase small subunit [EC:1.12.99.6]
D SiH_0915 coenzyme F420-reducing hydrogenase alpha subunit-like protein K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D SiH_0910 nickel-dependent hydrogenase, large subunit K23549 hupV; uptake hydrogenase large subunit [EC:1.12.99.6]
D SiH_0891 hydrogenase (NiFe) small subunit HydA K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D SiH_0920 nickel-dependent hydrogenase small subunit K06282 hyaA; hydrogenase small subunit [EC:1.12.99.6]
D SiH_0892 [NiFe] hydrogenase large subunit, HyaB K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
D SiH_0921 Ni Fe-hydrogenase I large subunit-like protein K06281 hyaB; hydrogenase large subunit [EC:1.12.99.6]
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:sih02024]
D SiH_1273 anthranilate synthase component I K01657 trpE; anthranilate synthase component I [EC:4.1.3.27]
D SiH_1272 glutamine amidotransferase of anthranilate synthase K01658 trpG; anthranilate synthase component II [EC:4.1.3.27]
D SiH_2400 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D SiH_2403 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D SiH_2404 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D SiH_2401 ABC transporter related protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D SiH_2402 ABC transporter related protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D SiH_0769 beta-lactamase domain protein K13075 ahlD; N-acyl homoserine lactone hydrolase [EC:3.1.1.81]
D SiH_2238 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_1710 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_2332 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_0903 extracellular solute-binding protein, family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_0951 conserved hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_2246 maltose binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_2255 oligopeptide binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_2598 cellobiose binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_0902 peptide ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_0952 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2243 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2251 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2333 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2599 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2651 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_0901 ABC-type dipeptide/oligopeptide/nickel transport systems, permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_0953 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2242 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2252 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2334 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2597 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2652 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_0900 oligo/dipeptide transport, ATP binding protein (dppD-1) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2244 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2653 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2253 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2596 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2335 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_0954 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2654 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_2595 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_2254 ABC transporter related protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_2336 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_0955 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_1389 SecY protein K03076 secY; preprotein translocase subunit SecY
D SiH_1733 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SiH_1197 GTP-binding signal recognition particle SRP54, G-domain K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D SiH_1253 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism [PATH:sih04980]
D SiH_1703 ATP-cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D SiH_1509 ATP/cobalamin adenosyltransferase K00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]
D SiH_0075 LAO/AO transport system ATPase K07588 MMAA; GTPase [EC:3.6.5.-]
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:sih01000]
C 01001 Protein kinases [BR:sih01001]
D SiH_1649 Kae1-associated kinase, Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D SiH_0177 Non-specific serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D SiH_1882 conserved hypothetical protein K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
C 01009 Protein phosphatases and associated proteins [BR:sih01009]
D SiH_0181 translation initiation factor IF2/IF5 K03238 EIF2S2; translation initiation factor 2 subunit 2
D SiH_1332 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
C 01002 Peptidases and inhibitors [BR:sih01002]
D SiH_1940 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D SiH_0883 [NiFe] hydrogenase-specific C-terminal protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D SiH_0896 hypothetical protein K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D SiH_0928 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
D SiH_0842 Pyroglutamyl-peptidase I K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
D SiH_0246 GMP synthase, small subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SiH_2080 GMP synthase domain protein K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D SiH_1467 Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SiH_1468 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D SiH_1699 glucosamine-fructose-6-phosphateamino transferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SiH_0946 glutamine amidotransferase class-II K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
D SiH_1112 intracellular protease, PfpI family K26818 pfpI; archaeal arginyl aminopeptidase [EC:3.4.11.27]
D SiH_0890 abortive infection protein K07052 K07052; CAAX protease family protein
D SiH_2728 Peptidase M1 membrane alanine aminopeptidase K13722 trf2_3; tricorn protease interacting factor F2/3 [EC:3.4.11.-]
D SiH_2593 Peptidase M1 membrane alanine aminopeptidase K13722 trf2_3; tricorn protease interacting factor F2/3 [EC:3.4.11.-]
D SiH_0698 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D SiH_0511 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D SiH_0785 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
D SiH_0386 amidohydrolase K13048 cps; carboxypeptidase Ss1 [EC:3.4.17.-]
D SiH_1972 methionine aminopeptidase, type II K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D SiH_1716 peptidase M24 K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
D SiH_2054 peptidase M24 K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
D SiH_2202 Carboxypeptidase Taq K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D SiH_0692 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D SiH_2563 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D SiH_2081 peptidase M48 Ste24p K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
D SiH_1398 peptidase zinc-dependent K06974 amzA; archaemetzincin [EC:3.4.-.-]
D SiH_1250 peptidase S26B, signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D SiH_0483 membrane protein K13280 SEC11; signal peptidase I [EC:3.4.21.89]
D SiH_2190 proline-specific peptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
D SiH_0853 peptidase S41 K08676 tri; tricorn protease [EC:3.4.21.-]
D SiH_1007 peptidase S45 penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11]
D SiH_1349 Proteasome endopeptidase complex K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D SiH_1321 proteasome endopeptidase complex K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D SiH_1800 Proteasome endopeptidase complex K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D SiH_0151 peptidase T2 asparaginase 2 K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
D SiH_2089 Gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
D SiH_1441 Zn-dependent protease K03592 pmbA; PmbA protein
D SiH_1040 peptidase U62 modulator of DNA gyrase K03592 pmbA; PmbA protein
D SiH_1442 Zn-dependent protease K03568 tldD; TldD protein
D SiH_1041 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein
C 01003 Glycosyltransferases [BR:sih01003]
D SiH_2005 glycosyl transferase family 4 K01001 ALG7; UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15]
D SiH_1127 oligosaccharyl transferase STT3 subunit K07151 STT3; dolichyl-diphosphooligosaccharide---protein glycosyltransferase [EC:2.4.99.18]
D SiH_2072 glycosyl transferase family 2 K00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]
D SiH_0188 glycosyl transferase family 2 K19003 mgdA; 1,2-diacylglycerol 3-beta-glucosyltransferase [EC:2.4.1.336]
D SiH_1183 starch synthase K00703 glgA; starch synthase [EC:2.4.1.21]
C 01005 Lipopolysaccharide biosynthesis proteins [BR:sih01005]
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:sih01011]
D SiH_0693 hypothetical protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
D SiH_0695 hypothetical protein K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]
C 01004 Lipid biosynthesis proteins [BR:sih01004]
D SiH_0087 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0101 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_2193 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_1194 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0297 short-chain dehydrogenase/reductase SDR K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D SiH_0033 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0576 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0727 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0496 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_2388 acetate--CoA ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0614 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0624 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0646 AMP-dependent synthetase and ligase K01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]
D SiH_0681 acetyl coenzyme A synthetase (ADP forming), alpha domain protein K24012 acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]
D SiH_2238 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_1710 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_0318 AMP-dependent synthetase and ligase K00666 K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]
C 01008 Polyketide biosynthesis proteins [BR:sih01008]
D SiH_0314 beta-lactamase domain protein K05555 actIV; cyclase [EC:4.-.-.-]
C 01006 Prenyltransferases [BR:sih01006]
D SiH_2004 Farnesyltranstransferase K13787 idsA; geranylgeranyl diphosphate synthase, type I [EC:2.5.1.1 2.5.1.10 2.5.1.29]
D SiH_1945 4-hydroxybenzoate polyprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D SiH_1446 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:sih01007]
D SiH_1977 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SiH_1988 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SiH_1626 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D SiH_0092 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SiH_1302 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SiH_1536 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SiH_1364 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SiH_1268 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SiH_1579 tRNA synthetase valyl/leucyl anticodon-binding protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1508 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1979 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D SiH_1909 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D SiH_1799 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SiH_1637 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D SiH_1496 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SiH_1527 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SiH_0285 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SiH_1740 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SiH_0949 alanyl-tRNA synthetase-like protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SiH_1970 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SiH_1969 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SiH_1270 aminotransferase class I and II K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D SiH_1631 aminotransferase class I and II K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1506 histidinol-phosphate aminotransferase K00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]
D SiH_1923 acetylornithine and succinylornithine aminotransferase K05830 lysJ; [amino-group carrier protein]-gamma-(L-lysyl/L-ornithyl)-L-glutamate aminotransferase [EC:2.6.1.118 2.6.1.124]
D SiH_2095 aminotransferase class-III K00823 puuE; 4-aminobutyrate aminotransferase [EC:2.6.1.19]
D SiH_1898 glutamate-1-semialdehyde-2,1-aminomutase K01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:sih03000]
D SiH_1811 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SiH_1220 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D SiH_0148 transcriptional regulator, AsnC family K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D SiH_1926 transcriptional regulator, AsnC family K06154 lysM; Lrp/AsnC family transcriptional regulator, involved in the regulation of lysine biosynthesis
D SiH_0058 ferric uptake regulator, Fur family K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
D SiH_1878 transcriptional regulator, ArsR family K22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor
D SiH_1611 transcriptional regulator K22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator
D SiH_1177 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator
D SiH_1409 iron (metal) dependent repressor, DtxR family K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D SiH_0084 iron dependent repressor K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator
D SiH_1404 biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D SiH_1657 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D SiH_0611 transcriptional regulator, TrmB K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D SiH_1113 molybdenum transport protein ModA related protein (ModA) K02019 modE; molybdate transport system regulatory protein
D SiH_0869 CRISPR-associated DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D SiH_0408 CRISPR-associated Csa3, DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D SiH_0760 CRISPR-associated, Csa3, DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D SiH_0413 CRISPR-asscoiated, Csa3, putative transcriptional regulator K07725 csa3; CRISPR-associated protein Csa3
D SiH_1229 transcriptional regulator, XRE family K07728 K07728; putative transcriptional regulator
D SiH_1694 transcriptional regulator, XRE family K07731 K07731; putative transcriptional regulator
D SiH_1443 putative transcriptional regulator, CopG family K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
D SiH_2671 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D SiH_0023 transcriptional activator, TenA family K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D SiH_0668 transcriptional regulator, PaaX family K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
C 03021 Transcription machinery [BR:sih03021]
D SiH_1633 transcription factor TFIIB K03124 TFIIB; transcription initiation factor TFIIB
D SiH_1226 Zinc finger TFIIB-type domain protein K03124 TFIIB; transcription initiation factor TFIIB
D SiH_1220 TATA-box binding family protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D SiH_1810 Transcription factor TFIIE, alpha subunit K03136 TFIIE1; transcription initiation factor TFIIE subunit alpha
D SiH_1765 XPD repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D SiH_1664 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4
D SiH_1735 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5
D SiH_1135 conserved hypothetical protein K24104 GPN; GPN-loop GTPase
D SiH_1852 KH type 2 domain protein K02600 nusA; transcription termination/antitermination protein NusA
D SiH_1849 DNA-directed RNA polymerase subunit A' K03041 rpoA1; DNA-directed RNA polymerase subunit A' [EC:2.7.7.6]
D SiH_1850 DNA-directed RNA polymerase, subunit A'' K03042 rpoA2; DNA-directed RNA polymerase subunit A" [EC:2.7.7.6]
D SiH_1848 RNA polymerase Rpb2 domain 6 K13798 rpoB; DNA-directed RNA polymerase subunit B [EC:2.7.7.6]
D SiH_1994 RNA polymerase, subunit D K03047 rpoD; DNA-directed RNA polymerase subunit D [EC:2.7.7.6]
D SiH_1665 DNA-directed RNA polymerase K03049 rpoE1; DNA-directed RNA polymerase subunit E' [EC:2.7.7.6]
D SiH_1801 DNA-directed RNA polymerase, subunit G (RpoG) K03052 rpoG; DNA-directed RNA polymerase subunit G [EC:2.7.7.6]
D SiH_1847 RNA polymerase Rpb5 K03053 rpoH; DNA-directed RNA polymerase subunit H [EC:2.7.7.6]
D SiH_1259 RNA polymerase Rpb6 K03055 rpoK; DNA-directed RNA polymerase subunit K [EC:2.7.7.6]
D SiH_1785 RNA polymerase dimerization K03056 rpoL; DNA-directed RNA polymerase subunit L [EC:2.7.7.6]
D SiH_1998 RNA polymerase, subunit N K03058 rpoN; DNA-directed RNA polymerase subunit N [EC:2.7.7.6]
D SiH_1635 RNA polymerase Rbp10 K03059 rpoP; DNA-directed RNA polymerase subunit P [EC:2.7.7.6]
D SiH_1682 conserved hypothetical protein K00960 rpo13; DNA-directed RNA polymerase subunit 13 [EC:2.7.7.6]
D SiH_1786 DNA-directed RNA polymerase, putative subunit M (RpoM-like) K03057 tfs; transcription factor S
D SiH_1787 transcription termination factor Tfs K03057 tfs; transcription factor S
D SiH_1493 DNA-directed RNA polymerase, M/15 kDa subunit K03057 tfs; transcription factor S
C 03019 Messenger RNA biogenesis [BR:sih03019]
D SiH_1664 DNA-directed RNA polymerase subunit E, RpoE2 K15171 SUPT4H1; transcription elongation factor SPT4
D SiH_1735 NusG antitermination factor K15172 SUPT5H; transcription elongation factor SPT5
D SiH_1661 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_1904 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_1984 translation factor pelota K06965 PELO; protein pelota
D SiH_0142 eRF1 domain 2 protein K03265 ETF1; peptide chain release factor subunit 1
D SiH_0225 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D SiH_1856 elongation factor EF-1, alpha subunit K03231 EEF1A; elongation factor 1-alpha
D SiH_1784 RNA binding S1 domain protein K07573 CSL4; exosome complex component CSL4
D SiH_1351 KH type 1 domain protein K03679 RRP4; exosome complex component RRP4
D SiH_1352 exosome complex exonuclease 1 K11600 RRP41; exosome complex component RRP41
D SiH_1353 3' exoribonuclease K12589 RRP42; exosome complex component RRP42
D SiH_1253 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 03041 Spliceosome [BR:sih03041]
D SiH_0224 ZPR1-related zinc finger protein K06874 ZPR1; zinc finger protein ZPR1
C 03011 Ribosome [BR:sih03011]
D SiH_1342 ribosomal protein S3Ae K02984 RP-S3Ae; small subunit ribosomal protein S3Ae
D SiH_1378 Ribosomal protein S4E, central domain protein K02987 RP-S4e; small subunit ribosomal protein S4e
D SiH_1668 Ribosomal protein S6e K02991 RP-S6e; small subunit ribosomal protein S6e
D SiH_1920 ribosomal protein S8e K02995 RP-S8e; small subunit ribosomal protein S8e
D SiH_1792 ribosomal protein S17E (rps17E) K02962 RP-S17e; small subunit ribosomal protein S17e
D SiH_1726 Ribosomal protein S19e K02966 RP-S19e; small subunit ribosomal protein S19e
D SiH_1646 ribosomal protein S24E (rps24E) K02974 RP-S24e; small subunit ribosomal protein S24e
D SiH_1658 ribosomal protein S25e K02975 RP-S25e; small subunit ribosomal protein S25e
D SiH_1526 30S ribosomal protein S26e K02976 RP-S26e; small subunit ribosomal protein S26e
D SiH_1130 Ribosomal protein S27E K02978 RP-S27e; small subunit ribosomal protein S27e
D SiH_1647 ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D SiH_1843 Ribosomal protein S28e K02979 RP-S28e; small subunit ribosomal protein S28e
D SiH_1233 ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e
D SiH_1367 ribosomal protein L4/L1e K02930 RP-L4e; large subunit ribosomal protein L4e
D SiH_1978 ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D SiH_1782 ribosomal protein L16 K02866 RP-L10e; large subunit ribosomal protein L10e
D SiH_1685 ribosomal protein L14 K02875 RP-L14e; large subunit ribosomal protein L14e
D SiH_1345 Ribosomal protein L15e K02877 RP-L15e; large subunit ribosomal protein L15e
D SiH_1995 ribosomal protein L15 K02883 RP-L18e; large subunit ribosomal protein L18e
D SiH_1384 Ribosomal protein L19e K02885 RP-L19e; large subunit ribosomal protein L19e
D SiH_1336 ribosomal protein L21e K02889 RP-L21e; large subunit ribosomal protein L21e
D SiH_1844 Ribosomal protein L24E K02896 RP-L24e; large subunit ribosomal protein L24e
D SiH_1851 ribosomal protein L7Ae/L30e/S12e/Gadd45 K02908 RP-L30e; large subunit ribosomal protein L30e
D SiH_1729 ribosomal protein L31E (rpl31E) K02910 RP-L31e; large subunit ribosomal protein L31e
D SiH_1383 Ribosomal protein L32e K02912 RP-L32e; large subunit ribosomal protein L32e
D SiH_1392 Ribosomal protein L34e K02915 RP-L34e; large subunit ribosomal protein L34e
D SiH_1330 Ribosomal protein L37e K02922 RP-L37e; large subunit ribosomal protein L37e
D SiH_1354 50S ribosomal protein L37 K02921 RP-L37Ae; large subunit ribosomal protein L37Ae
D SiH_1728 Ribosomal protein L39e K02924 RP-L39e; large subunit ribosomal protein L39e
D SiH_1911 Ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D SiH_1131 Ribosomal protein L44E K02929 RP-L44e; large subunit ribosomal protein L44e
D SiH_1999 ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D SiH_1372 ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D SiH_1992 ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D SiH_1386 ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D SiH_1855 ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D SiH_1381 ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D SiH_1997 ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D SiH_1857 ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D SiH_1993 ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D SiH_1853 ribosomal protein S23 (S12) K02950 RP-S12; small subunit ribosomal protein S12
D SiH_1991 ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D SiH_1380 ribosomal protein S14 K02954 RP-S14; small subunit ribosomal protein S14
D SiH_1670 Ribosomal S13S15 domain protein K02956 RP-S15; small subunit ribosomal protein S15
D SiH_1375 ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D SiH_1370 ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D SiH_1737 ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D SiH_1369 ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D SiH_1366 ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D SiH_1379 ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D SiH_1382 ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D SiH_1738 ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D SiH_1736 ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D SiH_1996 ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D SiH_1376 ribosomal protein L14b K02874 RP-L14; large subunit ribosomal protein L14
D SiH_1388 ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D SiH_1385 ribosomal protein L18P/L5E K02881 RP-L18; large subunit ribosomal protein L18
D SiH_1371 ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D SiH_1368 Ribosomal protein L25/L23 K02892 RP-L23; large subunit ribosomal protein L23
D SiH_1377 ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D SiH_1373 ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D SiH_1387 ribosomal protein L30P K02907 RP-L30; large subunit ribosomal protein L30
D SiH_1739 ribosomal protein 60S K02869 RP-L12; large subunit ribosomal protein L12
D SiH_1731 ribosomal LX protein K02944 RP-LX; large subunit ribosomal protein LX
D SiH_r0003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D SiH_r0002 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D SiH_r0001 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:sih03009]
D SiH_1232 Pre-mRNA processing ribonucleoprotein, binding domain protein K14564 NOP56; nucleolar protein 56
D SiH_1128 RNA-binding protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D SiH_1355 Brix domain-containing protein K14561 IMP4; U3 small nucleolar ribonucleoprotein protein IMP4
D SiH_0043 Suppressor Mra1 family protein K14568 EMG1; rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260]
D SiH_0176 KH type 1 domain protein K06961 KRR1; ribosomal RNA assembly protein
D SiH_0177 Non-specific serine/threonine protein kinase K07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]
D SiH_1882 conserved hypothetical protein K07179 RIOK2; RIO kinase 2 [EC:2.7.11.1]
D SiH_1618 nucleotide kinase-like protein K18532 AK6; adenylate kinase [EC:2.7.4.3]
D SiH_1543 Protein of unknown function DUF367 K09140 TSR3; rRNA small subunit aminocarboxypropyltransferase [EC:2.5.1.157]
D SiH_1790 ABC transporter related protein K06174 ABCE1; ATP-binding cassette, sub-family E, member 1
D SiH_1474 small GTP-binding protein K06943 NOG1; nucleolar GTP-binding protein
D SiH_1374 archaeal RNase P subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D SiH_1348 archaeal RNase P subunit p14 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D SiH_1347 archaeal RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D SiH_1306 GTPase or GTP-binding protein K06947 GRC3; polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-]
D SiH_1730 translation initiation factor eIF-6 K03264 EIF6; translation initiation factor 6
D SiH_0183 NMD3 family protein K07562 NMD3; 60S ribosomal export protein NMD3
D SiH_1350 putative RNA-associated protein K14574 SDO1; ribosome maturation protein SDO1
D SiH_1661 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_1904 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_1231 Non-specific serine/threonine protein kinase K04795 flpA; fibrillarin-like pre-rRNA processing protein
D SiH_1978 ribosomal protein L7Ae K02936 RP-L7Ae; large subunit ribosomal protein L7Ae
D SiH_1852 KH type 2 domain protein K02600 nusA; transcription termination/antitermination protein NusA
D SiH_1339 ribosomal RNA adenine methylase transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D SiH_1949 Fmu (Sun) domain protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D SiH_1708 Fmu (Sun) domain protein K03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]
D SiH_1865 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D SiH_1985 ribosomal-protein-alanine acetyltransferase K03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]
D SiH_1808 GTP-binding proten HflX K03665 hflX; GTPase
D SiH_1405 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D SiH_0041 RNA-binding protein, KH domain K07574 yhbY; RNA-binding protein
D SiH_1344 GTPase of unknown function K06942 ychF; ribosome-binding ATPase
D SiH_1093 conserved hypothetical protein K22469 fau-1; probable ribonuclease FAU-1 [EC:3.1.26.-]
C 03016 Transfer RNA biogenesis [BR:sih03016]
D SiH_1374 archaeal RNase P subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D SiH_1348 archaeal RNase P subunit p14 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D SiH_1347 archaeal RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D SiH_0042 archaeal RNase P subunit p21 K03540 RPR2; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]
D SiH_1138 ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D SiH_1202 archaeal RNA splicing ligase K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D SiH_1397 conserved hypothetical protein K24956 ZBTB8OS; protein archease
D SiH_0225 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D SiH_1856 elongation factor EF-1, alpha subunit K03231 EEF1A; elongation factor 1-alpha
D SiH_1977 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SiH_1527 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D SiH_1364 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D SiH_1579 tRNA synthetase valyl/leucyl anticodon-binding protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1508 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1536 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D SiH_1302 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SiH_1979 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D SiH_1740 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SiH_0949 alanyl-tRNA synthetase-like protein K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D SiH_1637 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D SiH_0285 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D SiH_1496 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D SiH_0092 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D SiH_1268 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D SiH_1799 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D SiH_1970 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D SiH_1969 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D SiH_1988 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SiH_1626 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D SiH_0052 tRNA deacylase K09716 dtdA; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D SiH_1629 Threonyl/alanyl tRNA synthetase SAD K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
D SiH_2737 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D SiH_0180 RNA modification enzyme, MiaB family K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
D SiH_1228 N2,N2-dimethylguanosine tRNA methyltransferase K00555 TRMT1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]
D SiH_0237 conserved hypothetical protein K15429 TRM5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D SiH_1655 tRNA methyltransferase complex GCD14 subunit K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D SiH_1601 Methyltransferase type 11 K15444 TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]
D SiH_2142 conserved hypothetical protein K22900 TRMO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]
D SiH_1215 Wyosine base formation domain protein K15449 TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]
D SiH_0039 putative methyltransferase K07055 TRM12; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]
D SiH_1477 Protein of unknown function DUF207 K15450 TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]
D SiH_1687 H/ACA RNA-protein complex component, Cbf5p K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D SiH_1686 H/ACA RNA-protein complex component, Cbf5p K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D SiH_1908 tRNA pseudouridine synthase, TruD family, aPus7 K06176 truD; tRNA pseudouridine13 synthase [EC:5.4.99.27]
D SiH_1649 Kae1-associated kinase, Bud32 K08851 TP53RK; TP53 regulating kinase and related kinases [EC:2.7.11.1]
D SiH_1648 O-sialoglycoprotein endopeptidase/protein kinase, archaeal protein Kae1 K01409 OSGEP; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]
D SiH_1600 histone acetyltransferase, ELP3 family K07739 ELP3; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]
D SiH_1405 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D SiH_1314 THUMP domain protein K06963 TAN1; tRNA acetyltransferase TAN1
D SiH_mr0001 RNase P RNA K01978 rnpB; M1 RNA
D SiH_1142 tRNA cytidylyltransferase K07558 K07558; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]
D SiH_1798 archaeal intron splicing enzyme, beta subunit K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D SiH_1641 archaeal intron splicing enzyme, alpha subunit K01170 endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]
D SiH_1141 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D SiH_1909 aspartyl-tRNA synthetase K09759 aspC; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]
D SiH_1825 RNA methylase, NOL1/NOP2/sun family K22901 trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]
D SiH_1099 tRNA (guanine-N1-)-methyltransferase K15566 trm10; tRNA (adenine9-N1/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221]
D SiH_1137 putative RNA methylase K07446 trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]
D SiH_1809 conserved hypothetical protein K07254 atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]
D SiH_0674 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D SiH_1063 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D SiH_2217 SirA family protein K04085 tusA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]
D SiH_2586 ExsB family protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D SiH_2046 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D SiH_1475 Radical SAM domain protein K10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]
D SiH_1803 tRNA-guanine transglycosylase, various specificities K18779 tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]
D SiH_1745 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D SiH_1819 domain of unknown function DUF1743 K06932 tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]
D SiH_1689 ATPase of unknown function K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
D SiH_2092 conserved hypothetical protein K06957 tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]
C 03012 Translation factors [BR:sih03012]
D SiH_0178 translation initiation factor eIF-1A K03236 EIF1A; translation initiation factor 1A
D SiH_1634 translation initiation factor SUI1 K03113 EIF1; translation initiation factor 1
D SiH_1129 translation initiation factor 2, alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
D SiH_0181 translation initiation factor IF2/IF5 K03238 EIF2S2; translation initiation factor 2 subunit 2
D SiH_1667 translation initiation factor IF-2 subunit gamma K03242 EIF2S3; translation initiation factor 2 subunit 3
D SiH_2315 translation initiation factor, aIF-2BI family K03239 EIF2B1; translation initiation factor eIF-2B subunit alpha
D SiH_1198 translation initiation factor eIF-5A K03263 EIF5A; translation initiation factor 5A
D SiH_1846 translation initiation factor aIF-2 K03243 EIF5B; translation initiation factor 5B
D SiH_1730 translation initiation factor eIF-6 K03264 EIF6; translation initiation factor 6
D SiH_0225 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D SiH_1856 elongation factor EF-1, alpha subunit K03231 EEF1A; elongation factor 1-alpha
D SiH_1905 translation elongation factor aEF-1 beta K03232 EEF1B; elongation factor 1-beta
D SiH_1359 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D SiH_1783 diphthamide biosynthesis protein K07561 DPH1; 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108]
D SiH_1418 ATP binding protein K06927 DPH6; diphthine-ammonia ligase [EC:6.3.1.14]
D SiH_0142 eRF1 domain 2 protein K03265 ETF1; peptide chain release factor subunit 1
D SiH_1340 methylase K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D SiH_1907 Aminoacyl-tRNA hydrolase K04794 PTH2; peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29]
C 03110 Chaperones and folding catalysts [BR:sih03110]
D SiH_1796 thermosome K22447 cct; archaeal chaperonin
D SiH_1297 thermosome K22447 cct; archaeal chaperonin
D SiH_2297 thermosome K22447 cct; archaeal chaperonin
D SiH_0223 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D SiH_2665 heat shock protein Hsp20 K13993 HSP20; HSP20 family protein
D SiH_1732 prefoldin, alpha subunit K04797 pfdA; prefoldin alpha subunit
D SiH_1357 prefoldin, beta subunit K04798 pfdB; prefoldin beta subunit
D SiH_0930 hydrogenase expression/synthesis HypA K04651 hypA; hydrogenase nickel incorporation protein HypA/HybF
D SiH_0817 cytoplasmic chaperone TorD family protein K23349 dmsD; putative dimethyl sulfoxide reductase chaperone
D SiH_1328 peptidylprolyl isomerase FKBP-type K03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]
D SiH_0050 thioredoxin K03671 TXN; thioredoxin
D SiH_1711 thioredoxin K03671 TXN; thioredoxin
C 04131 Membrane trafficking [BR:sih04131]
D SiH_1845 Nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D SiH_1661 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_1904 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_1257 AAA ATPase central domain protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D SiH_2291 glycosyl hydrolase 38 domain protein K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D SiH_1187 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SiH_0225 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D SiH_1856 elongation factor EF-1, alpha subunit K03231 EEF1A; elongation factor 1-alpha
C 04121 Ubiquitin system [BR:sih04121]
D SiH_1911 Ribosomal protein L40e K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
D SiH_1647 ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D SiH_1233 ribosomal protein S30e K02983 RP-S30e; small subunit ribosomal protein S30e
C 03051 Proteasome [BR:sih03051]
D SiH_1349 Proteasome endopeptidase complex K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
D SiH_1321 proteasome endopeptidase complex K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D SiH_1800 Proteasome endopeptidase complex K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
D SiH_1806 26S proteasome subunit P45 family K03420 psmR; proteasome regulatory subunit
C 03032 DNA replication proteins [BR:sih03032]
D SiH_1134 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1673 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D SiH_1902 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D SiH_1890 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D SiH_1811 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SiH_1128 RNA-binding protein Nop10p K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
D SiH_1358 nucleotide excision repair nuclease, Xpf K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D SiH_1987 TOPRIM domain protein K02316 dnaG; DNA primase [EC:2.7.7.101]
D SiH_0002 oriC2 Cdc6-3 K10725 cdc6A; archaeal cell division control protein 6
D SiH_1315 oriC3 Cdc6-2 K10725 cdc6A; archaeal cell division control protein 6
D SiH_1820 oriC1 Cdc6-1 K10725 cdc6A; archaeal cell division control protein 6
D SiH_1312 MCM family protein K10726 mcm; replicative DNA helicase Mcm [EC:5.6.2.3]
D SiH_1133 DNA primase small subunit, PriSL K02683 priS; DNA primase small subunit [EC:2.7.7.102]
D SiH_1537 DNA primase, large subunit K18882 priL; DNA primase large subunit
D SiH_1313 conserved hypothetical protein K09723 ginS; DNA replication factor GINS
D SiH_0184 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D SiH_1986 DNA polymerase B exonuclease K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D SiH_0714 DNA polymerase elongation subunit (family B) K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D SiH_1542 DNA polymerase B region K02319 pol; DNA polymerase, archaea type [EC:2.7.7.7]
D SiH_1318 AAA ATPase central domain protein K04800 rfcL; replication factor C large subunit
D SiH_1319 Replication factor C K04801 rfcS; replication factor C small subunit
D SiH_1199 DNA topoisomerase (ATP-hydrolyzing) K03166 top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]
D SiH_1200 DNA topoisomerase VI, B subunit K03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]
D SiH_1258 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D SiH_1660 reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-]
D SiH_1206 reverse gyrase K03170 topG; reverse gyrase [EC:5.6.2.2 5.6.2.-]
C 03036 Chromosome and associated proteins [BR:sih03036]
D SiH_1811 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SiH_1365 Protein of unknown function DUF171 K09142 SPOUT1; methyltransferase [EC:2.1.1.-]
D SiH_0136 conserved hypothetical protein K03609 minD; septum site-determining protein MinD
D SiH_2028 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
D SiH_1705 XerC/D integrase-recombinase protein K04763 xerD; integrase/recombinase XerD
D SiH_1619 MRP protein-like protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D SiH_0929 conserved hypothetical protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
C 03400 DNA repair and recombination proteins [BR:sih03400]
D SiH_0286 methylated DNA-protein cysteine methyltransferase, Ada K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SiH_0267 Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SiH_1956 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D SiH_1134 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1673 proliferating cell nuclear antigen PcnA K04802 PCNA; proliferating cell nuclear antigen
D SiH_1681 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D SiH_1902 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D SiH_1890 DNA ligase I, ATP-dependent Dnl1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D SiH_1765 XPD repair helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D SiH_1358 nucleotide excision repair nuclease, Xpf K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D SiH_1257 AAA ATPase central domain protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
D SiH_0090 Nudix hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SiH_0086 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SiH_2528 Uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D SiH_0102 exodeoxyribonuclease III Xth K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D SiH_2730 Xylose isomerase domain protein TIM barrel K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D SiH_0249 Deoxyribonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D SiH_0063 Rad50 recombination repair enzyme like protein K03546 sbcC; DNA repair protein SbcC/Rad50
D SiH_0064 Mre11 recombination repair enzyme like protein K03547 sbcD; DNA repair protein SbcD/Mre11
D SiH_0410 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D SiH_0762 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D SiH_1827 DNA repair and recombination protein RadA K04483 radA; DNA repair protein RadA
D SiH_1016 resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D SiH_1522 Resolvase, Holliday junction-type K03552 hjr; holliday junction resolvase [EC:3.1.21.10]
D SiH_0065 HerA recombination helicase like protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
D SiH_0062 NurA 5'-3' nuclease K25510 nurA; DNA double-strand break repair nuclease NurA [EC:3.1.-.-]
D SiH_0257 DEAD/DEAH box helicase domain protein K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
D SiH_1258 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D SiH_0243 DNA-directed DNA polymerase K04479 dbh; DNA polymerase IV (archaeal DinB-like DNA polymerase) [EC:2.7.7.7]
D SiH_1959 DEAD/H associated domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D SiH_1684 DEAD/DEAH box helicase domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D SiH_1204 DEAD/DEAH box helicase domain protein K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D SiH_1238 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SiH_0296 ribonucleotide reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SiH_1289 Protein of unknown function DUF650 K22585 nreA; DNA repair protein NreA
D SiH_2518 Protein of unknown function DUF650 K22585 nreA; DNA repair protein NreA
C 03029 Mitochondrial biogenesis [BR:sih03029]
D SiH_1374 archaeal RNase P subunit p29 K03538 POP4; ribonuclease P protein subunit POP4 [EC:3.1.26.5]
D SiH_1348 archaeal RNase P subunit p14 K03537 POP5; ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5]
D SiH_1347 archaeal RNase P subunit p30 K03539 RPP1; ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5]
D SiH_1988 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D SiH_1579 tRNA synthetase valyl/leucyl anticodon-binding protein K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1508 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D SiH_1637 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D SiH_1302 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D SiH_1322 amidase K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SiH_1214 glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D SiH_1841 glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D SiH_1213 glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D SiH_1619 MRP protein-like protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D SiH_0929 conserved hypothetical protein K03593 mrp; ATP-binding protein involved in chromosome partitioning
D SiH_1446 protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:sih02000]
D SiH_2284 Domain of unknown function DUF1854 K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D SiH_1151 extracellular solute-binding protein family 1 K15495 wtpA; molybdate/tungstate transport system substrate-binding protein
D SiH_1150 ABC-type sulfate transport system, permease, CysU K15496 wtpB; molybdate/tungstate transport system permease protein
D SiH_1712 ABC transporter related protein K15497 wtpC; molybdate/tungstate transport system ATP-binding protein [EC:7.3.2.5 7.3.2.6]
D SiH_0262 ABC-type anion transport system, duplicated permease K02050 ABC.SN.P; NitT/TauT family transport system permease protein
D SiH_0263 ABC transporter related protein K02049 ABC.SN.A; NitT/TauT family transport system ATP-binding protein
D SiH_2545 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D SiH_1024 ABC transporter related protein K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
D SiH_1021 extracellular solute-binding protein family 1 K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D SiH_1022 ABC-type sugar transport system, permease, UgpA K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SiH_1023 ABC-type maltose transport system, permease, MalG K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SiH_2399 glucose binding protein K10196 glcS; glucose/arabinose transport system substrate-binding protein
D SiH_2237 arabinose binding protein K10196 glcS; glucose/arabinose transport system substrate-binding protein
D SiH_2398 ABC-type sugar transport system, permease, UgpA K10197 glcT; glucose/arabinose transport system permease protein
D SiH_2236 ABC-type sugar transport systems, permease, UgpA K10197 glcT; glucose/arabinose transport system permease protein
D SiH_2235 ABC-type sugar transport system, permease, UgpE K10198 glcU; glucose/arabinose transport system permease protein
D SiH_2397 ABC-type sugar transport system, permease, UgpE K10198 glcU; glucose/arabinose transport system permease protein
D SiH_2396 ABC transporter related protein K10199 glcV; glucose/arabinose transport system ATP-binding protein
D SiH_2234 ABC transporter related protein K10199 glcV; glucose/arabinose transport system ATP-binding protein
D SiH_1170 trehalose binding protein K17311 treS; trehalose transport system substrate-binding protein
D SiH_1169 ABC-type sugar transport systems, permease, UgpA K17312 treT; trehalose transport system permease protein
D SiH_1168 ABC-type sugar transport system, permease, UgpE K17313 treU; trehalose transport system permease protein
D SiH_1167 ABC transporter related protein K17314 treV; trehalose transport system ATP-binding protein
D SiH_2546 extracellular solute-binding protein family 1 K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D SiH_0581 hypothetical protein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D SiH_2544 ABC-type sugar transport system, permease, UgpA K02025 ABC.MS.P; multiple sugar transport system permease protein
D SiH_1592 ABC transporter related protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SiH_2400 Extracellular ligand-binding receptor K01999 livK; branched-chain amino acid transport system substrate-binding protein
D SiH_2403 inner-membrane translocator K01997 livH; branched-chain amino acid transport system permease protein
D SiH_2404 inner-membrane translocator K01998 livM; branched-chain amino acid transport system permease protein
D SiH_2401 ABC transporter related protein K01995 livG; branched-chain amino acid transport system ATP-binding protein
D SiH_2402 ABC transporter related protein K01996 livF; branched-chain amino acid transport system ATP-binding protein
D SiH_2332 extracellular solute-binding protein family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_0903 extracellular solute-binding protein, family 5 K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_0951 conserved hypothetical protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_2246 maltose binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_2255 oligopeptide binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_2598 cellobiose binding protein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SiH_0902 peptide ABC transporter, permease protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_0952 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2243 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2251 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2333 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2599 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_2651 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SiH_0901 ABC-type dipeptide/oligopeptide/nickel transport systems, permease K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_0953 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2242 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2252 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2334 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppB K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2597 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_2652 ABC-type dipeptide/oligopeptide/nickel transport system, permease, DppC K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SiH_0900 oligo/dipeptide transport, ATP binding protein (dppD-1) K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2244 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2653 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2253 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2596 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2335 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_0954 oligopeptide/dipeptide ABC transporter, ATPase subunit K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SiH_2654 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_2595 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_2254 ABC transporter related protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_2336 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_0955 oligopeptide/dipeptide ABC transporter, ATPase subunit K02032 ddpF; peptide/nickel transport system ATP-binding protein
D SiH_1595 periplasmic binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D SiH_1942 periplasmic binding protein K02016 ABC.FEV.S; iron complex transport system substrate-binding protein
D SiH_1594 transport system permease protein K02015 ABC.FEV.P; iron complex transport system permease protein
D SiH_1593 ABC transporter related protein K02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]
D SiH_0655 cobalt transport protein K16785 ecfT; energy-coupling factor transport system permease protein
D SiH_0656 ABC transporter related protein K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SiH_0200 ABC-type Na+ efflux pump permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_0749 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_0505 putative ABC-2 type transport permease K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_1050 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_2144 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_0323 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_0960 conserved hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_2011 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_2619 ABC-2 type transporter K01992 ABC-2.P; ABC-2 type transport system permease protein
D SiH_0198 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_0748 ABC transporter ATP-binding protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_0506 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_1049 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_0945 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_2143 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_2669 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_0324 daunorubicin resistance ABC transporter ATP-binding subunit, DrrA K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_0959 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_2010 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_2618 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_1148 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_2210 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_2221 ABC transporter related protein K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SiH_1424 conserved hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SiH_1104 conserved hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SiH_1106 ABC transporter related protein K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SiH_1242 FeS assembly ATPase SufC K09013 sufC; Fe-S cluster assembly ATP-binding protein
D SiH_0794 major facilitator superfamily MFS_1 K06610 iolF; MFS transporter, SP family, inositol transporter
D SiH_0648 major facilitator superfamily MFS_1 K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D SiH_0348 Oxalate/Formate Antiporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
D SiH_2540 major facilitator superfamily MFS_1 K08194 dgoT; MFS transporter, ACS family, D-galactonate transporter
D SiH_1013 phosphate:H+ symporter K08176 PHO84; MFS transporter, PHS family, inorganic phosphate transporter
D SiH_2127 General substrate transporter K08176 PHO84; MFS transporter, PHS family, inorganic phosphate transporter
D SiH_0036 major facilitator superfamily MFS_1 K08221 yitG; MFS transporter, ACDE family, multidrug resistance protein
D SiH_0996 major facilitator superfamily MFS_1 K08369 ydjE; MFS transporter, putative metabolite:H+ symporter
D SiH_1095 von Willebrand factor type A K07114 yfbK; Ca-activated chloride channel homolog
D SiH_1098 von Willebrand factor type A K07114 yfbK; Ca-activated chloride channel homolog
D SiH_1545 MscS Mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel
D SiH_2491 MscS Mechanosensitive ion channel K03442 mscS; small conductance mechanosensitive channel
D SiH_0602 Mg2 transporter protein CorA family protein K03284 corA; magnesium transporter
D SiH_0061 Co/Zn/Cd efflux system component, CzcD K16264 czcD; cobalt-zinc-cadmium efflux system protein
D SiH_2230 ZIP family zinc transporter K07238 TC.ZIP; zinc transporter, ZIP family
D SiH_0710 conserved hypothetical protein K15268 eamA; O-acetylserine/cysteine efflux transporter
D SiH_0349 L-lactate transport K03303 lutP; lactate permease
D SiH_1018 sodium/calcium exchanger membrane region K07301 yrbG; cation:H+ antiporter
D SiH_2111 sodium/calcium exchanger membrane region K07301 yrbG; cation:H+ antiporter
D SiH_1054 sodium/hydrogen exchanger K26730 napA; Na+:H+ antiporter
D SiH_0800 permease for cytosine/purines uracil thiamine allantoin K10974 codB; cytosine permease
D SiH_2104 Chloride channel core K03281 clcA; chloride channel protein, CIC family
D SiH_1164 high-affinity nickel-transporter K07241 hoxN; nickel/cobalt transporter (NiCoT) family protein
D SiH_0936 high-affinity nickel-transporter K07241 hoxN; nickel/cobalt transporter (NiCoT) family protein
D SiH_2300 manganese transporter, putative K03322 mntH; manganese transport protein
D SiH_0459 polysaccharide biosynthesis protein K06409 spoVB; stage V sporulation protein B
D SiH_2065 transmembrane protein, unknown function DUF125 K22736 VIT; vacuolar iron transporter family protein
D SiH_2699 conserved hypothetical protein K22736 VIT; vacuolar iron transporter family protein
D SiH_1491 multiple antibiotic resistance (MarC)-related protein K05595 marC; multiple antibiotic resistance protein
D SiH_1930 AAA ATPase K25503 cedB; DNA import protein CedB
D SiH_1395 conserved hypothetical protein K25504 cedA; DNA import protein CedA
D SiH_1394 conserved hypothetical protein K25505 cedA1; DNA import protein CedA1
D SiH_1396 hypothetical protein K25506 cedA2; DNA import protein CedA2
C 02044 Secretion system [BR:sih02044]
D SiH_0128 flagellin K07325 flaB; archaeal flagellin FlaB
D SiH_0125 flagellar protein F K07329 flaF; archaeal flagellar protein FlaF
D SiH_0126 putative flagellar protein FlaG K07330 flaG; archaeal flagellar protein FlaG
D SiH_0124 flagellar accessory protein FlaH K07331 flaH; archaeal flagellar protein FlaH
D SiH_0123 ATPase involved in archaeal flagella biosynthesis K07332 flaI; archaeal flagellar protein FlaI
D SiH_0187 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D SiH_2576 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D SiH_1951 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D SiH_0122 archaeal flagella assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_0186 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_2577 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_1952 conserved hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_1940 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
D SiH_1389 SecY protein K03076 secY; preprotein translocase subunit SecY
D SiH_1197 GTP-binding signal recognition particle SRP54, G-domain K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D SiH_1733 signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D SiH_1919 conserved hypothetical protein K03105 SRP19; signal recognition particle subunit SRP19
D SiH_1597 sec-independent translocation protein mttA/Hcf106 K03116 tatA; sec-independent protein translocase protein TatA
D SiH_1598 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D SiH_2200 twin-arginine translocation protein, TatA/E family subunit K03116 tatA; sec-independent protein translocase protein TatA
D SiH_1596 Sec-independent protein translocase, TatC subunit K03118 tatC; sec-independent protein translocase protein TatC
D SiH_2199 Sec-independent periplasmic protein translocase K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:sih02042]
C 02022 Two-component system
C 02035 Bacterial motility proteins [BR:sih02035]
D SiH_0128 flagellin K07325 flaB; archaeal flagellin FlaB
D SiH_0125 flagellar protein F K07329 flaF; archaeal flagellar protein FlaF
D SiH_0126 putative flagellar protein FlaG K07330 flaG; archaeal flagellar protein FlaG
D SiH_0124 flagellar accessory protein FlaH K07331 flaH; archaeal flagellar protein FlaH
D SiH_0123 ATPase involved in archaeal flagella biosynthesis K07332 flaI; archaeal flagellar protein FlaI
D SiH_0187 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D SiH_2576 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D SiH_1951 type II secretion system protein E K07332 flaI; archaeal flagellar protein FlaI
D SiH_0122 archaeal flagella assembly protein J K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_0186 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_2577 type II secretion system protein K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_1952 conserved hypothetical protein K07333 flaJ; archaeal flagellar protein FlaJ
D SiH_1940 Peptidase A24B, FlaK domain protein K07991 flaK; archaeal preflagellin peptidase FlaK [EC:3.4.23.52]
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:sih04812]
D SiH_2000 conserved hypothetical protein K06990 MEMO1; MEMO1 family protein
D SiH_0136 conserved hypothetical protein K03609 minD; septum site-determining protein MinD
D SiH_2028 Cobyrinic acid ac-diamide synthase K03496 parA; chromosome partitioning protein
C 04147 Exosome [BR:sih04147]
D SiH_1253 Phosphopyruvate hydratase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D SiH_1547 phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D SiH_1187 pyruvate kinase K00873 PK; pyruvate kinase [EC:2.7.1.40]
D SiH_0698 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
D SiH_0353 peroxiredoxin (PRX) family K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D SiH_0225 protein synthesis factor GTP-binding protein K03231 EEF1A; elongation factor 1-alpha
D SiH_1856 elongation factor EF-1, alpha subunit K03231 EEF1A; elongation factor 1-alpha
D SiH_1359 translation elongation factor aEF-2 K03234 EEF2; elongation factor 2
D SiH_1902 XPG I domain protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D SiH_1647 ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
D SiH_1661 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_1904 AAA family ATPase, CDC48 subfamily K13525 VCP; transitional endoplasmic reticulum ATPase
D SiH_2737 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D SiH_2238 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_1710 AMP-dependent synthetase and ligase K01897 ACSL; long-chain acyl-CoA synthetase [EC:6.2.1.3]
D SiH_2390 selenium-binding protein K17285 SELENBP1; methanethiol oxidase [EC:1.8.3.4]
D SiH_0179 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0621 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_0622 acetyl-CoA acetyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2378 Thiolase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2640 propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1553 acetyl-CoA C-acetyltransferase (acetoacetyl-CoAthiolase) (AcaB-1) K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_2561 Propanoyl-CoA C-acyltransferase K00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]
D SiH_1332 adenosylhomocysteinase K01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]
D SiH_1390 adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D SiH_1461 argininosuccinate lyase K01755 argH; argininosuccinate lyase [EC:4.3.2.1]
D SiH_1462 Argininosuccinate synthase K01940 argG; argininosuccinate synthase [EC:6.3.4.5]
D SiH_2241 Alpha-L-fucosidase K01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]
D SiH_0838 glycerol kinase K00864 glpK; glycerol kinase [EC:2.7.1.30]
D SiH_0238 glutamine synthetase catalytic region K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1713 glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_2707 Glutamate--ammonia ligase K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D SiH_1899 porphobilinogen synthase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D SiH_0005 transcriptional coactivator/pterin dehydratase K01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]
D SiH_1261 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein K00058 serA; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]
D SiH_0586 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_1066 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2703 FAD-dependent pyridine nucleotide-disulphideoxido reductase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D SiH_2498 Electron transfer flavoprotein alpha subunit K03522 fixB; electron transfer flavoprotein alpha subunit
D SiH_0598 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_0642 Glu/Leu/Phe/Val dehydrogenase K00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]
D SiH_2678 Triose-phosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:sih02048]
D SiH_0410 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D SiH_0762 CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D SiH_0411 CRISPR-associated protein Cas2 K09951 cas2; CRISPR-associated protein Cas2
D SiH_0756 CRISPR-associated, Cas3, DEAD-like helicase K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D SiH_0404 CRISPR-associated helicase Cas3 K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4]
D SiH_0403 CRISPR-associated HD domain protein K07475 cas3; CRISPR-associated endonuclease Cas3-HD [EC:3.1.-.-]
D SiH_0409 CRISPR-associated protein, Csa1 K19085 csa1; CRISPR-associated protein Csa1
D SiH_0406 CRISPR-associated Csa2, autoregulator DevR family K19074 csa2; CRISPR-associated protein Csa2
D SiH_0869 CRISPR-associated DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D SiH_0408 CRISPR-associated Csa3, DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D SiH_0760 CRISPR-associated, Csa3, DNA-binding protein K07725 csa3; CRISPR-associated protein Csa3
D SiH_0413 CRISPR-asscoiated, Csa3, putative transcriptional regulator K07725 csa3; CRISPR-associated protein Csa3
D SiH_0412 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D SiH_0772 conserved hypothetical protein K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D SiH_2061 CRISPR-associated protein Cas4 K07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]
D SiH_0405 CRISPR-associated protein Cas5 family K19089 cas5a_b_c; CRISPR-associated protein Cas5a/b/c
D SiH_0757 CRISPR-associated, crenarchaeal family 3 protein K19120 csc1; CRISPR-associated protein Csc1
D SiH_0758 CRISPR-associated, crenarchaeal family 3 protein K19121 csc2; CRISPR-associated protein Csc2
D SiH_0759 CRISPR-associated protein, crenarchaeal family 3 protein K19122 csc3; CRISPR-associated protein Csc3
D SiH_0557 CRISPR-associated protein, Cmr2 family K19076 cmr2; CRISPR-associated protein Cmr2
D SiH_0558 CRISPR-associatedprotein, Cmr3 K09127 cmr3; CRISPR-associated protein Cmr3
D SiH_0553 CRISPR-associated RAMP protein, Cmr4 family K09000 cmr4; CRISPR-associated protein Cmr4
D SiH_0556 CRISPR-associated RAMP protein, Cmr6 family K19142 cmr6; CRISPR-associated protein Cmr6
D SiH_0402 CRISPR-associated Casx protein K19146 csaX; CRISPR-associated protein CsaX
D SiH_1435 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
D SiH_1436 type I restriction-modification system specificity subunit K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
D SiH_1437 type 1 restriction modification enzyme, subunit m K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
D SiH_0775 hypothetical protein K07317 K07317; adenine-specific DNA-methyltransferase [EC:2.1.1.72]
D SiH_1811 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D SiH_2174 VapB-type antitoxin K07172 mazE; antitoxin MazE
D SiH_2135 VapB-like antitoxin K19156 prlF; antitoxin PrlF
D SiH_0509 conserved hypothetical protein K06218 relE; mRNA interferase RelE/StbE
D SiH_1568 conserved hypothetical protein K06218 relE; mRNA interferase RelE/StbE
D SiH_1868 conserved hypothetical protein K06218 relE; mRNA interferase RelE/StbE
D SiH_0750 VapB-type antitoxin K19164 ccdA; antitoxin CcdA
D SiH_1656 putative transcriptional regulator, CopG/Arc/MetJ family K07746 parD1_3_4; antitoxin ParD1/3/4
D SiH_0639 conserved hypothetical protein K07341 doc; death on curing protein
D SiH_1977 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D SiH_0034 Nucleotide binding protein PINc K07060 nob1; endoribonuclease Nob1 [EC:3.1.-.-]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules [BR:sih04090]
C 01504 Antimicrobial resistance genes
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:sih00537]
D SiH_0698 peptidase M19 renal dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:sih03100]
D SiH_t0002 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SiH_t0033 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SiH_t0027 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D SiH_t0008 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0031 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0020 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0030 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0029 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D SiH_t0045 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D SiH_t0037 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D SiH_t0006 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SiH_t0024 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D SiH_t0010 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D SiH_t0022 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D SiH_t0019 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SiH_t0026 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SiH_t0023 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D SiH_t0038 tRNA-His K14226 tRNA-His; tRNA His
D SiH_t0003 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D SiH_t0005 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0016 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0001 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0009 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0015 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D SiH_t0040 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SiH_t0041 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D SiH_t0014 tRNA-Met K14230 tRNA-Met; tRNA Met
D SiH_t0021 tRNA-Met K14230 tRNA-Met; tRNA Met
D SiH_t0036 tRNA-Met K14230 tRNA-Met; tRNA Met
D SiH_t0017 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D SiH_t0004 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SiH_t0028 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SiH_t0046 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D SiH_t0044 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0013 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0025 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0035 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D SiH_t0007 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SiH_t0034 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SiH_t0047 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D SiH_t0043 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D SiH_t0012 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D SiH_t0011 tRNA-Val K14237 tRNA-Val; tRNA Val
D SiH_t0032 tRNA-Val K14237 tRNA-Val; tRNA Val
D SiH_t0042 tRNA-Val K14237 tRNA-Val; tRNA Val
D SiH_r0002 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D SiH_r0001 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D SiH_r0003 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D SiH_r0004 7S ribosomal RNA K01983 ffs; SRP RNA
D SiH_mr0001 RNase P RNA K01978 rnpB; M1 RNA
#
A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D SiH_0585 dehydrogenase E1 component K21416 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-]
D SiH_2480 Pyruvate dehydrogenase (acetyl-transferring) K21416 acoA; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha [EC:1.1.1.-]
D SiH_2479 Transketolase central region K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-]
D SiH_0584 Transketolase central region K21417 acoB; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta [EC:1.1.1.-]
D SiH_2245 aldo/keto reductase K23107 yajO; 1-deoxyxylulose-5-phosphate synthase [EC:1.1.-.-]
D SiH_0229 (2Fe-2S)-binding domain protein K03518 coxS; aerobic carbon-monoxide dehydrogenase small subunit [EC:1.2.5.3]
D SiH_0230 molybdopterin dehydrogenase FAD-binding protein K03519 coxM; aerobic carbon-monoxide dehydrogenase medium subunit [EC:1.2.5.3]
D SiH_2725 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3]
D SiH_0859 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3]
D SiH_2350 aldehyde oxidase and xanthine dehydrogenasemolybdopterin binding protein K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3]
D SiH_2500 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3]
D SiH_2074 Carbon-monoxide dehydrogenase (acceptor) K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3]
D SiH_2288 aldehyde oxidase and xanthine dehydrogenase molybdopterin binding protein K03520 coxL; aerobic carbon-monoxide dehydrogenase large subunit [EC:1.2.5.3]
D SiH_0616 thiamine pyrophosphate domain, TPP-binding protein K00179 iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8]
D SiH_0615 pyruvate ferredoxin/flavodoxin oxidoreductase K00180 iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8]
D SiH_2558 TENA/THI-4 domain protein K06137 pqqC; pyrroloquinoline-quinone synthase [EC:1.3.3.11]
D SiH_2422 FAD dependent oxidoreductase K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D SiH_2484 FAD dependent oxidoreductase K00313 fixC; electron transfer flavoprotein-quinone oxidoreductase [EC:1.5.5.-]
D SiH_0095 CoA-disulfide reductase K18367 CoADR; CoA-dependent NAD(P)H sulfur oxidoreductase [EC:1.8.1.18]
D SiH_0396 methionine sulfoxide reductase A K07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]
D SiH_0068 peroxiredoxin family, PRX K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D SiH_0613 peroxiredoxin (PRX) family K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D SiH_2656 peroxiredoxin (PRX) family, AhpE-like subfamily K24129 K24129; glutaredoxin-dependent peroxiredoxin [EC:1.11.1.25]
D SiH_0998 Pirin domain protein K06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]
D SiH_2567 mercuric reductase K00520 merA; mercuric reductase [EC:1.16.1.1]
D SiH_0038 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K21567 fnr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]
D SiH_1838 Radical SAM domain protein K06937 E1.21.98.5; tetraether lipid synthase [EC:1.21.98.5]
D SiH_1449 Radical SAM domain protein K04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]
D SiH_1157 hydrogenase 4 membrane component (E)-like protein K12140 hyfE; hydrogenase-4 component E [EC:1.-.-.-]
D SiH_1158 NADH dehydrogenase (quinone) K12141 hyfF; hydrogenase-4 component F [EC:1.-.-.-]
D SiH_2670 Protein-L-isoaspartate (D-aspartate)O-methyltransferase K00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]
D SiH_1218 diphthine synthase K20215 dph5; diphthine synthase [EC:2.1.1.98]
D SiH_1201 deoxyhypusine synthase K00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]
D SiH_1538 CDP-alcohol phosphatidyltransferase K17884 E2.7.8.39; archaetidylinositol phosphate synthase [EC:2.7.8.39]
D SiH_0971 Appr-1-p processing domain protein K23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]
D SiH_0106 thioesterase superfamily protein K07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]
D SiH_0371 phosphohistidine phosphatase SixA K08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]
D SiH_1154 TatD-related deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D SiH_2016 TatD-related deoxyribonuclease K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D SiH_0663 DNA-binding 7 kDa protein K16640 ssh7; DNA-binding protein 7 [EC:3.1.27.-]
D SiH_2711 DNA-binding 7 kDa protein K16640 ssh7; DNA-binding protein 7 [EC:3.1.27.-]
D SiH_0025 conserved hypothetical protein K07503 nucS; endonuclease [EC:3.1.-.-]
D SiH_2275 Alpha-glucosidase K01811 xylS; alpha-D-xyloside xylohydrolase [EC:3.2.1.177]
D SiH_1262 DNA-(apurinic or apyrimidinic site) lyase K03653 K03653; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D SiH_2100 endoribonuclease L-PSP K09022 ridA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]
D SiH_0164 MoxR-like ATPase K03924 moxR; MoxR-like ATPase [EC:3.6.3.-]
D SiH_0575 carbonic anhydrase K20499 csh; carbon disulfide hydrolase [EC:3.13.1.5]
D SiH_1823 conserved hypothetical protein K22205 E3.13.2.3; S-adenosyl-L-methionine hydrolase (adenosine-forming) [EC:3.13.2.3]
D SiH_0067 carbohydrate kinase, YjeF related protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D SiH_0241 RNA 3'-phosphate cyclase K01974 RTCA; RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4]
C 99981 Carbohydrate metabolism
D SiH_2696 sugar fermentation stimulation protein K06206 sfsA; sugar fermentation stimulation protein A
D SiH_2033 histone deacetylase superfamily K04768 acuC; acetoin utilization protein AcuC
D SiH_1071 histone deacetylase superfamily K04768 acuC; acetoin utilization protein AcuC
D SiH_2179 conserved hypothetical protein K00782 lldG; L-lactate dehydrogenase complex protein LldG
C 99982 Energy metabolism
D SiH_2419 formate dehydrogenase family accessory protein FdhD K02379 fdhD; FdhD protein
D SiH_2020 cytochrome c oxidase subunit I K16933 doxB; heme bearing subunit I of the terminal oxidase
D SiH_2019 terminal oxidase, subunit (DoxC) K16934 doxC; terminal oxidase subunit
D SiH_2018 terminal oxidase, small hydrophobic subunit (DoxE) K16935 doxE; terminal oxidase small hydrophobic subunit
D SiH_2497 Electron transfer flavoprotein alpha/beta-subunit K03521 fixA; electron transfer flavoprotein beta subunit
D SiH_2421 4Fe-4S ferredoxin iron-sulfur binding domain protein K03855 fixX; ferredoxin like protein
D SiH_2485 4Fe-4S ferredoxin iron-sulfur binding domain protein K03855 fixX; ferredoxin like protein
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
D SiH_1415 molybdopterin-guanine dinucleotide biosynthesis protein B K03753 mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein
C 99988 Secondary metabolism
C 99999 Others
D SiH_2550 DoxX family protein K15977 K15977; putative oxidoreductase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D SiH_1807 transcriptional regulator, XRE family K03627 MBF1; putative transcription factor
D SiH_1207 DNA/RNA-binding protein Alba K03622 ssh10b; archaea-specific DNA-binding protein
D SiH_1205 Alba, DNA/RNA-binding protein K03622 ssh10b; archaea-specific DNA-binding protein
D SiH_1329 Sm ribonucleoprotein core-like protein K04796 RUXX; small nuclear ribonucleoprotein
D SiH_1879 Like-Sm ribonucleoprotein core K04796 RUXX; small nuclear ribonucleoprotein
D SiH_2734 transcriptional regulator-like protein K07743 K07743; transcriptional regulator
D SiH_1961 putative signal transduction protein with CBS domains K07744 K07744; transcriptional regulator
C 99974 Translation
D SiH_1338 Protein of unknown function DUF655 K07572 K07572; putative nucleotide binding protein
D SiH_1695 beta-lactamase domain protein K07577 K07577; putative mRNA 3-end processing factor
D SiH_1891 exonuclease, beta-lactamase fold, RNA processing K07577 K07577; putative mRNA 3-end processing factor
D SiH_2732 methyltransferase type 11 K07579 K07579; putative methylase
D SiH_1906 Protein of unknown function DUF1610 K07580 K07580; Zn-ribbon RNA-binding protein
D SiH_1346 Protein of unknown function DUF54 K07581 K07581; RNA-binding protein
C 99975 Protein processing
D SiH_0980 conserved hypothetical protein K03187 ureE; urease accessory protein
D SiH_0981 urease accessory protein UreF K03188 ureF; urease accessory protein
D SiH_0982 urease accessory protein UreG K03189 ureG; urease accessory protein
D SiH_0884 hydrogenase expression/formation protein (HUPF/HYPC) K04653 hypC; hydrogenase expression/formation protein HypC
D SiH_0887 hydrogenase assembly chaperone hypC/hupF K04653 hypC; hydrogenase expression/formation protein HypC
D SiH_0886 hydrogenase formation HypD protein K04654 hypD; hydrogenase expression/formation protein HypD
D SiH_0889 hydrogenase expression/formation protein HypE K04655 hypE; hydrogenase expression/formation protein HypE
D SiH_2549 AIR synthase related protein domain protein K04655 hypE; hydrogenase expression/formation protein HypE
D SiH_2009 AIR synthase-like protein domain K04655 hypE; hydrogenase expression/formation protein HypE
D SiH_0913 (NiFe) hydrogenase maturation protein HypF K04656 hypF; hydrogenase maturation protein HypF
D SiH_1990 AIR synthase related protein K07388 K07388; hydrogenase expression/formation protein
D SiH_1805 PUA domain containing protein K07398 K07398; conserved protein with predicted RNA binding PUA domain
D SiH_0573 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family K07402 xdhC; xanthine dehydrogenase accessory factor
D SiH_0720 xanthine and Co dehydrogenase maturation factor K07402 xdhC; xanthine dehydrogenase accessory factor
D SiH_2374 xanthine dehydrogenase accessory factor K07402 xdhC; xanthine dehydrogenase accessory factor
C 99976 Replication and repair
D SiH_2346 IS607 family transposase K07450 K07450; putative resolvase
D SiH_0283 HhH-GPD family protein K07457 K07457; endonuclease III related protein
D SiH_0245 TIP49 domain protein K07472 TIP49; TBP-interacting protein
D SiH_1457 Translin K07477 K07477; translin
D SiH_1440 IS110 family transposase K07486 K07486; transposase
D SiH_0329 hypothetical protein K07486 K07486; transposase
D SiH_2581 IS110 family transposase K07486 K07486; transposase
D SiH_0764 IS110 family transposase K07486 K07486; transposase
D SiH_2580 IS110 family transposase K07486 K07486; transposase
D SiH_2266 IS110 family transposase K07486 K07486; transposase
D SiH_0490 IS110 family transposase K07486 K07486; transposase
D SiH_0117 IS110 family transposase K07486 K07486; transposase
D SiH_0530 IS110 family transposase K07486 K07486; transposase
D SiH_0739 IS110 family transposase K07486 K07486; transposase
D SiH_0747 IS110 family transposase K07486 K07486; transposase
D SiH_1932 transposase IS116/IS110/IS902 family protein K07486 K07486; transposase
D SiH_2588 IS110 family transposase K07486 K07486; transposase
D SiH_2590 IS6 family transposase K07489 K07489; transposase
D SiH_0606 IS6 family transposase K07489 K07489; transposase
D SiH_0589 IS200/IS605 family OrfA transposase K07491 rayT; REP-associated tyrosine transposase
D SiH_0605 IS200/IS605 family OrfA transposase K07491 rayT; REP-associated tyrosine transposase
D SiH_0871 IS200/IS605 family OrfA transposase K07491 rayT; REP-associated tyrosine transposase
D SiH_2675 IS200/IS605 family OrfA transposase K07491 rayT; REP-associated tyrosine transposase
D SiH_0494 ISH3 family transposase K07495 K07495; putative transposase
D SiH_0520 ISH3 family transposase K07495 K07495; putative transposase
D SiH_2330 ISH3 family transposase K07495 K07495; putative transposase
D SiH_1427 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0493 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0526 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0700 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0590 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0604 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0989 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0999 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0438 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0645 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0870 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_1030 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_1036 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_2676 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_2716 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_2286 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_2056 IS200/IS605 family OrfB-related protein K07496 K07496; putative transposase
D SiH_0694 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0839 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
D SiH_0363 IS200/IS605 family OrfB protein K07496 K07496; putative transposase
C 99979 Viral proteins
C 99998 Others
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D SiH_0273 Na+/solute symporter K03307 TC.SSS; solute:Na+ symporter, SSS family
D SiH_0644 permease for cytosine/purines uracil thiamine allantoin K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
D SiH_0738 permease for cytosine/purine, uracil, thiamine, allantoin K03457 TC.NCS1; nucleobase:cation symporter-1, NCS1 family
C 99978 Cell growth
D SiH_0905 cobyrinic acid ac-diamide synthase K07321 cooC; CO dehydrogenase maturation factor
C 99993 Cell motility
C 99995 Signaling proteins
D SiH_1143 Ser/Thr kinase-like protein K07176 K07176; putative serine/threonine protein kinase
D SiH_1727 DNA-binding TFAR19-related protein K06875 PDCD5; programmed cell death protein 5
C 99992 Structural proteins
C 99994 Others
B
B 09194 Poorly characterized
C 99996 General function prediction only
D SiH_1523 Nucleotide binding protein PINc K06865 K06865; ATPase
D SiH_2044 DEAD/DEAH box helicase domain protein K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D SiH_1432 helicase domain protein K06877 K06877; DEAD/DEAH box helicase domain-containing protein
D SiH_1473 methionyl-tRNA synthetase, beta subunit K06878 K06878; tRNA-binding protein
D SiH_1613 integral membrane protein, putative K06994 K06994; putative drug exporter of the RND superfamily
D SiH_0836 conserved prokaryal membrane protein K06994 K06994; putative drug exporter of the RND superfamily
D SiH_1360 HAD-superfamily hydrolase, subfamily IA, variant1 K07025 K07025; putative hydrolase of the HAD superfamily
D SiH_2733 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 K07025; putative hydrolase of the HAD superfamily
D SiH_1241 FeS assembly protein SufB K09014 sufB; Fe-S cluster assembly protein SufB
D SiH_0317 Aryldialkylphosphatase K07048 PTER; phosphotriesterase-related protein
D SiH_1304 uncharacterized Zn finger-containing protein K07143 K07143; UPF0148 protein
D SiH_1188 conserved hypothetical protein K00389 yidH; putative membrane protein
D SiH_1223 Protein of unknown function DUF373 K08975 K08975; putative membrane protein
D SiH_0156 membrane protein K08979 K08979; putative membrane protein
D SiH_0683 conserved hypothetical protein K08980 K08980; putative membrane protein
D SiH_2159 conserved hypothetical protein K08980 K08980; putative membrane protein
C 99997 Function unknown
D SiH_1804 conserved hypothetical protein K06869 K06869; uncharacterized protein
D SiH_1245 conserved hypothetical protein K06869 K06869; uncharacterized protein
D SiH_0811 Radical SAM domain protein K06871 K06871; uncharacterized protein
D SiH_2341 radical SAM domain protein K06871 K06871; uncharacterized protein
D SiH_2183 metal dependent phosphohydrolase K06885 K06885; uncharacterized protein
D SiH_1975 metal dependent phosphohydrolase K06885 K06885; uncharacterized protein
D SiH_0021 conserved hypothetical protein K06888 K06888; uncharacterized protein
D SiH_0569 ATPase K06921 K06921; uncharacterized protein
D SiH_0969 archaeal ATPase (AAA+ superfamily) K06921 K06921; uncharacterized protein
D SiH_0867 ATPase K06921 K06921; uncharacterized protein
D SiH_0771 ATPase-like protein K06921 K06921; uncharacterized protein
D SiH_0932 hypothetical protein K06921 K06921; uncharacterized protein
D SiH_1076 CoA-binding domain protein K06929 K06929; uncharacterized protein
D SiH_2547 conserved hypothetical protein K06940 K06940; uncharacterized protein
D SiH_1219 phosphoesterase K06953 K06953; uncharacterized protein
D SiH_0737 photosystem I assembly BtpA K06971 K06971; uncharacterized protein
D SiH_2064 beta-lactamase domain protein K07022 K07022; uncharacterized protein
D SiH_1240 FeS assembly protein SufD K07033 K07033; uncharacterized protein
D SiH_2387 GPR1/FUN34/yaaH family protein K07034 K07034; uncharacterized protein
D SiH_1326 beta-lactamase domain protein K07041 K07041; uncharacterized protein
D SiH_0359 amidohydrolase 2 K07045 K07045; uncharacterized protein
D SiH_2708 amidohydrolase 2 K07045 K07045; uncharacterized protein
D SiH_0366 amidohydrolase 2 K07045 K07045; uncharacterized protein
D SiH_2279 amidohydrolase 2 K07045 K07045; uncharacterized protein
D SiH_0400 VapC-type toxin K07064 K07064; uncharacterized protein
D SiH_0743 VapC-type toxin K07064 K07064; uncharacterized protein
D SiH_2227 VapC-type toxin K07064 K07064; uncharacterized protein
D SiH_2689 VapC-type toxin K07064 K07064; uncharacterized protein
D SiH_2195 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_0306 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_2379 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_1552 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_0620 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_2639 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_0619 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_2560 conserved hypothetical protein K07068 K07068; uncharacterized protein
D SiH_1980 DNA polymerase beta domain protein K07073 K07073; uncharacterized protein
D SiH_0083 conserved hypothetical protein K07090 K07090; uncharacterized protein
D SiH_2358 conserved hypothetical protein K07090 K07090; uncharacterized protein
D SiH_2047 conserved hypothetical protein K07090 K07090; uncharacterized protein
D SiH_2220 peroxiredoxins-like protein K07092 K07092; uncharacterized protein
D SiH_1722 peroxiredoxins-like protein K07092 K07092; uncharacterized protein
D SiH_1065 DsrE family protein K07092 K07092; uncharacterized protein
D SiH_0840 metallophosphoesterase K07095 K07095; uncharacterized protein
D SiH_0863 phosphoesterase K07096 K07096; uncharacterized protein
D SiH_0054 metallophosphoesterase K07096 K07096; uncharacterized protein
D SiH_2536 metallophosphoesterase K07096 K07096; uncharacterized protein
D SiH_0251 phosphoesterase DHHA1 K07097 K07097; uncharacterized protein
D SiH_0143 phosphoribosyltransferase K07101 K07101; uncharacterized protein
D SiH_0220 phosphoribosyltransferase K07101 K07101; uncharacterized protein
D SiH_1237 transcriptional regulator-like protein K07108 K07108; uncharacterized protein
D SiH_2218 conserved hypothetical protein K07112 K07112; uncharacterized protein
D SiH_1152 short-chain dehydrogenase/reductase SDR K07124 K07124; uncharacterized protein
D SiH_1983 Radical SAM domain protein K07129 K07129; uncharacterized protein
D SiH_0398 AAA ATPase K07133 K07133; uncharacterized protein
D SiH_0559 DEXX-box ATPase K07133 K07133; uncharacterized protein
D SiH_0545 universally conserved protein K07133 K07133; uncharacterized protein
D SiH_0878 ATPase-like protein K07133 K07133; uncharacterized protein
D SiH_1031 putative ATP-binding protein K07133 K07133; uncharacterized protein
D SiH_0810 AAA ATPase K07133 K07133; uncharacterized protein
D SiH_2474 ATPase-like protein K07133 K07133; uncharacterized protein
D SiH_1832 FAD dependent oxidoreductase K07137 K07137; uncharacterized protein
D SiH_1666 PIN domain protein K07158 K07158; uncharacterized protein
D SiH_0253 conserved hypothetical protein K09003 K09003; uncharacterized protein
D SiH_1821 conserved hypothetical protein K09120 K09120; uncharacterized protein
D SiH_1885 conserved hypothetical protein K09122 K09122; uncharacterized protein
D SiH_1451 conserved hypothetical protein K09129 K09129; uncharacterized protein
D SiH_1886 AMMECR1 domain protein K09141 K09141; uncharacterized protein
D SiH_2679 Protein of unknown function DUF429 K09147 K09147; uncharacterized protein
D SiH_0182 Protein of unknown function DUF424 K09148 K09148; uncharacterized protein
D SiH_1881 Protein of unknown function DUF460 K09150 K09150; uncharacterized protein
D SiH_1723 conserved hypothetical protein K09157 K09157; uncharacterized protein
D SiH_1428 ATP/GTP binding protein K09384 K09384; uncharacterized protein
D SiH_0227 carbon monoxide dehydrogenase subunit G K09386 K09386; uncharacterized protein
D SiH_0319 carbon monoxide dehydrogenase subunit G K09386 K09386; uncharacterized protein
D SiH_0798 conserved hypothetical protein K09703 K09703; uncharacterized protein
D SiH_2571 Protein of unknown function DUF504 K09715 K09715; uncharacterized protein
D SiH_1861 DNA polymerase beta domain protein region K09717 K09717; uncharacterized protein
D SiH_1303 Protein of unknown function UPF0147 K09721 K09721; uncharacterized protein
D SiH_1511 conserved hypothetical protein K09732 K09732; uncharacterized protein
D SiH_1139 Protein of unknown function DUF54 K09736 K09736; uncharacterized protein
D SiH_1230 conserved hypothetical protein K09737 K09737; uncharacterized protein
D SiH_0040 conserved archaeal protein K09738 K09738; uncharacterized protein
D SiH_1604 conserved hypothetical protein K09744 K09744; uncharacterized protein
D SiH_0950 conserved hypothetical protein K09963 K09963; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024