+F Repair protein KO
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DNA Repair and Recombination Proteins - Solibacillus silvestris StLB046
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SSIL_0166 methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E SSIL_3438 uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SSIL_0647 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SSIL_2684 predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SSIL_0888 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0466 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_3165 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1822 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0745 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_3524 mutT; NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1104 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0317 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_2270 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0887 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1862 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1911 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1926 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_2466 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SSIL_0166 methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SSIL_0799 AraC-type DNA-binding domain-containing protein K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
C BER (base exicision repair)
D DNA glycosylases
E SSIL_3438 uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SSIL_0647 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SSIL_2234 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SSIL_1199 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SSIL_2684 predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SSIL_0390 exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SSIL_2844 endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E SSIL_1493 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SSIL_0494 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SSIL_1198 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SSIL_3258 excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
E SSIL_3259 helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
E SSIL_1257 nuclease subunit of the excinuclease complex K03703 uvrC; excinuclease ABC subunit C
E SSIL_0735 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_3543 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_3482 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_3499 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_0493 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_0817 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_1198 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SSIL_0494 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SSIL_0204 rpoB; DNA-directed RNA polymerase, beta subunit/140 kD subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SSIL_0205 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SSIL_0245 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SSIL_3401 DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F SSIL_3057 DNA-directed RNA polymerase, subunit K/omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SSIL_0027 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SSIL_1542 mutS; mismatch repair ATPase K03555 mutS; DNA mismatch repair protein MutS
E SSIL_1249 mismatch repair ATPase K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E SSIL_1543 mutL; DNA mismatch repair enzyme K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E SSIL_1699 exonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SSIL_1700 exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SSIL_1177 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SSIL_2957 DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E SSIL_0103 dnaN; DNA polymerase sliding clamp subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SSIL_1531 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SSIL_0051 ATPase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SSIL_0945 DNA polymerase III, alpha subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SSIL_0062 DNA polymerase III, gamma/tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SSIL_0494 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SSIL_0735 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_3543 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_3482 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_3499 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_0493 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_0817 superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SSIL_3355 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SSIL_0121 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SSIL_1500 ATP-dependent exoDNAse alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SSIL_2921 recA; RecA/RadA recombinase K03553 recA; recombination protein RecA
E SSIL_1482 holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E SSIL_1483 ruvB; holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SSIL_3055 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SSIL_0610 ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E SSIL_0609 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SSIL_2921 recA; RecA/RadA recombinase K03553 recA; recombination protein RecA
E SSIL_0186 radA; predicted ATP-dependent serine protease K04485 radA; DNA repair protein RadA/Sms
E SSIL_0101 recF; recombinational DNA repair ATPase K03629 recF; DNA replication and repair protein RecF
E SSIL_3039 RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SSIL_1493 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SSIL_2871 recO; recombinational DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
E SSIL_0060 recombinational DNA repair protein K06187 recR; recombination protein RecR
E SSIL_1705 recN; ATPase K03631 recN; DNA repair protein RecN (Recombination protein N)
E SSIL_2681 penicillin-binding protein-related factor A, putative recombinase K03700 recU; recombination protein U
E SSIL_1482 holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA
E SSIL_1483 ruvB; holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E SSIL_3248 ATP-dependent exoDNAse beta subunit K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E SSIL_3249 ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E SSIL_0610 ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E SSIL_0609 DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E SSIL_2189 uncharacterized conserved protein K10979 ku; DNA end-binding protein Ku
E SSIL_2188 predicted eukaryotic-type DNA primase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SSIL_0099 type IIA topoisomerase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SSIL_0100 type IIA topoisomerase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SSIL_3006 topA; topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SSIL_2725 bacterial nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SSIL_1493 single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SSIL_2871 recO; recombinational DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
F SSIL_0060 recombinational DNA repair protein K06187 recR; recombination protein RecR
F SSIL_0494 NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F SSIL_2118 superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SSIL_2741 superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SSIL_0815 superfamily II DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SSIL_3258 excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
F SSIL_3259 helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SSIL_2402 nucleotidyltransferase/DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SSIL_3465 nucleotidyltransferase/DNA polymerase K03502 umuC; DNA polymerase V
C Other SOS response factors
D SSIL_2921 recA; RecA/RadA recombinase K03553 recA; recombination protein RecA
D SSIL_1556 lexA; SOS-response transcriptional repressors K01356 lexA; repressor LexA [EC:3.4.21.88]
D SSIL_1705 recN; ATPase K03631 recN; DNA repair protein RecN (Recombination protein N)
D SSIL_3355 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SSIL_0121 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SSIL_0643 recX; uncharacterized protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D SSIL_1248 DNA polymerase IV K02347 polX; DNA polymerase (family X)
C DNA helicases
D SSIL_2673 Rad3-related DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D SSIL_2688 Rad3-related DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SSIL_0888 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0466 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_3165 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1822 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0745 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_3524 mutT; NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1104 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0317 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_2270 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_0887 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1862 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1911 ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_1926 NTP pyrophosphohydrolase including oxidative damage repair enzyme K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SSIL_2466 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SSIL_1643 ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SSIL_2469 ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SSIL_1641 ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SSIL_2624 ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D SSIL_2470 ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D SSIL_1176 exopolyphosphatase-related protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024