+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptomyces violaceus

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS C C7-C14 cyclized polyketide type D Octaketide PKS E RI060_18280 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E RI060_18275 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E RI060_18410 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E RI060_18350 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] D Nonaketide PKS E RI060_18280 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E RI060_18275 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E RI060_18410 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E RI060_18350 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] D Decaketide PKS E RI060_18280 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E RI060_18275 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E RI060_18410 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E RI060_18350 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] B Type III PKS C Plant type C Fungal type C Bacterial type D RI060_03355 type III polyketide synthase K16232 gcs; germicidin synthase D RI060_41770 3-oxoacyl-[acyl-carrier-protein] synthase III C-terminal domain-containing protein K16167 bpsA; alkylresorcinol/alkylpyrone synthase D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D RI060_04720 MbtH family protein K05375 mbtH; MbtH protein D RI060_04995 MbtH family protein K05375 mbtH; MbtH protein D RI060_18620 MbtH family NRPS accessory protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D RI060_06260 4'-phosphopantetheinyl transferase superfamily protein K02362 entD; enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7] C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase C Isonitrile lipopeptide synthase # APolyketide tailoring proteins B Hydrolase B Ketoreductase C RI060_37185 3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein K05556 actVI1; ketoreductase RED1 [EC:1.1.1.-] B Oxygenase C RI060_09015 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C RI060_20750 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C RI060_41370 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C RI060_32725 alpha/beta fold hydrolase K21159 sgcF; epoxide hydrolase C RI060_40830 epoxide hydrolase K21159 sgcF; epoxide hydrolase C RI060_18285 antibiotic biosynthesis monooxygenase family protein K15941 snoaB; deoxynogalonate / 12-deoxyaklanonic acid monooxygenase [EC:1.13.12.22 1.13.12.-] B Methylase C RI060_18400 methyltransferase domain-containing protein K15942 snoaC; O-methyltransferase / aklanonic acid methyltransferase [EC:2.1.1.- 2.1.1.288] C RI060_41775 isoprenylcysteine carboxylmethyltransferase family protein K16168 bpsB; methyltransferase B Glycosyltransferase C RI060_18255 activator-dependent family glycosyltransferase K24529 mycB; protomycinolide IV desosaminyltransferase [EC:2.4.1.-] C RI060_18360 activator-dependent family glycosyltransferase K24529 mycB; protomycinolide IV desosaminyltransferase [EC:2.4.1.-] B Halogenase C RI060_39175 AMP-binding protein K16431 cepH; FAD-dependent halogenase [EC:1.14.19.-] B beta-Branched incorporating proteins B Others C RI060_20875 3-hydroxyacyl-CoA dehydrogenase family protein K16024 asm13; methoxymalonate biosynthesis protein C RI060_20870 acyl carrier protein K16025 asm14; methoxymalonate biosynthesis acyl carrier protein C RI060_20865 acyl-CoA dehydrogenase family protein K16026 asm15; methoxymalonate biosynthesis protein C RI060_14550 hypothetical protein K14628 actVI2; enoyl reductase C RI060_18340 SDR family oxidoreductase K15944 snoaF; nogalaviketone/aklaviketone reductase [EC:1.1.1.- 1.1.1.362] # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase B Others C RI060_39330 amino acid racemase K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2025