+D Transcription factors KO
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Transcription Factors - Shewanella khirikhana
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
C AP-1(-like) components, Fos
C AP-1(-like) components, Maf
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
C CREB
C C/EBP-like factors
C bZIP/PAR
C Plant bZIP factors
C ZIP only
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
C Myogenic transcription factors
C Achaete-Scute
C Tal/Twist/Atonal/Hen, Lymphoid factors
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C Tal/Twist/Atonal/Hen, HEN
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
C Hairy, Fungal regulators
C Factors with PAS domain
C Yabby
C INO
C HLH domain only
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
C RF-X
C AP-2 (bHSH)
B Zinc finger
C Cys4 thyroid hormone receptor-like
C Cys4 hepatocyte nuclear factor 4-like
C Cys4 estrogen receptor-like
C Cys4 nerve growth factor IB-like
C Cys4 Fushi tarazu-F1-like
C Cys4 germ cell nuclear factor
C Cys4 Knirps/DAX1-like
C Cys4 GATA-factors
C Cys2His2 SP/KLF family and related proteins
C Cys2His2 GLI-like
C Cys2His2 Snail
C Cys2His2 BTB-ZF factors
C Cys2His2 BED
C Cys2His2 PRDM
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
C Cys2HisCys zinc factors
C Cys3His zinc factors
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D STH12_03993 bspRIM_1; Modification methylase BspRI K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D STH12_04082 bspRIM_2; Modification methylase BspRI K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
B Helix-turn-helix
C Homeo domain ANTP: HOXL
C Homeo domain ANTP: NKL
C Homeo domain Paired-related
C Homeo domain LIM
C Homeo domain POU
C Homeo domain SINE
C Homeo domain ZF
C Homeo domain CUT
C Homeo domain PROS
C Homeo domain TALE
C Homeo domain other
C Fork head/winged helix developmental regulators
C Fork head/winged helix tissue-specific regulators
C Fork head/winged helix cell cycle-controlling factors, E2F
C Fork head/winged helix cell cycle-controlling factors, DP
C Fork head/winged helix other regulators
C Stork head/winged helix factors
C Heat shock factors
C Tryptophan clusters Myb, Myb-factors
C Tryptophan clusters Myb, Myb-like factors
C Tryptophan clusters Ets-type
C Tryptophan clusters interferon-regulating factors
C TEA domain
C ARID
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
C RHR (Rel homology region) Ankyrin only
C RHR (Rel homology region) NF-AT
C STAT
C p53
C MADS-box regulators of differentiation, MEF-2
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
C SAND domain-containing proteins
C TATA-binding proteins
C HMG SOX
C HMG TCF-1
C HMG2-related
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
C Grainyhead
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
C Cold-shock domain factors, FRG Y2-like
C Runt
C MYRF
B Other transcription factors
C HMGI(Y)
C NUPR
C Pocket domain Rb
C Pocket domain CBP
C T-box
C DMRT
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
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AProkaryotic type
B Helix-turn-helix
C AraC family
D STH12_02745 rhaR; HTH-type transcriptional activator RhaR K18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA
D STH12_02787 melR; Melibiose operon regulatory protein K23237 melR; AraC family transcriptional regulator, melibiose operon regulatory protein
D STH12_03732 rob; Right origin-binding protein K13652 K13652; AraC family transcriptional regulator
D STH12_03588 tetD; Transposon Tn10 TetD protein K13653 K13653; AraC family transcriptional regulator
D STH12_01944 alkA; DNA-3-methyladenine glycosylase 2 K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D STH12_00311 cdhR_1; HTH-type transcriptional regulator CdhR K13633 ftrA; AraC family transcriptional regulator, transcriptional activator FtrA
C LysR family
D STH12_02208 gcvA_1; Glycine cleavage system transcriptional activator K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D STH12_03277 gcvA_3; Glycine cleavage system transcriptional activator K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D STH12_03292 gcvA_4; Glycine cleavage system transcriptional activator K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D STH12_03492 gcvA_5; Glycine cleavage system transcriptional activator K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D STH12_03210 cmpR_2; HTH-type transcriptional activator CmpR K02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC
D STH12_02518 hcaR_1; Hca operon transcriptional activator K03576 metR; LysR family transcriptional regulator, regulator for metE and metH
D STH12_00400 nhaR; Transcriptional activator protein NhaR K03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA
D STH12_00390 oxyR_1; Hydrogen peroxide-inducible genes activator K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator
D STH12_02895 iciA; Chromosome initiation inhibitor K05596 argP; LysR family transcriptional regulator, arginine and lysine transport system/DNA replication regulator
D STH12_00894 cysB; HTH-type transcriptional regulator CysB K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator
D STH12_00567 dmlR_3; HTH-type transcriptional regulator DmlR K18927 lldR; LysR family transcriptional regulator, L-lactate utilization regulator
D STH12_01294 catM; HTH-type transcriptional regulator CatM K21699 bauR; LysR family transcriptional regulator, transcriptional activator for bauABCD operon
D STH12_00230 cmpR_1; HTH-type transcriptional activator CmpR K21703 cbbR; LysR family transcriptional regulator, low CO2-responsive transcriptional regulator
D STH12_01687 yofA; HTH-type transcriptional regulator YofA K23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator
C DeoR family
D STH12_00755 srlR_1; Glucitol operon repressor K02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor
C LacI family
D STH12_00096 malI; Maltose regulon regulatory protein MalI K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D STH12_00465 exuR; putative HTH-type transcriptional repressor ExuR K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D STH12_00972 galR; HTH-type transcriptional regulator GalR K02529 galR; LacI family transcriptional regulator, galactose operon repressor
C GntR family
D STH12_03750 yvoA; HTH-type transcriptional repressor YvoA K05836 hutC; GntR family transcriptional regulator, histidine utilization repressor
D STH12_01613 fadR; Fatty acid metabolism regulator protein K03603 fadR; GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA
D STH12_04072 pdhR; Pyruvate dehydrogenase complex repressor K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
C TetR/AcrR family
D STH12_03194 putative HTH-type transcriptional regulator K18136 acrR; TetR/AcrR family transcriptional regulator, multidrug resistance operon repressor
D STH12_04012 slmA; Nucleoid occlusion factor SlmA K05501 slmA; TetR/AcrR family transcriptional regulator
D STH12_00316 DNA-binding transcriptional repressor AcrR K19736 aefR; TetR/AcrR family transcriptional regulator, regulator of autoinduction and epiphytic fitness
D STH12_00637 bdcR; HTH-type transcriptional repressor BdcR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D STH12_02183 comR; HTH-type transcriptional repressor ComR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D STH12_03095 nemR; HTH-type transcriptional repressor NemR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D STH12_03832 acuR; Transcriptional regulator AcuR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D STH12_02119 ttgW; putative HTH-type transcriptional regulator TtgW K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
D STH12_03880 fabR; HTH-type transcriptional repressor FabR K22105 fabR; TetR/AcrR family transcriptional regulator, fatty acid biosynthesis regulator
C Lrp/AsnC family
D STH12_00137 asnC_1; Regulatory protein AsnC K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D STH12_01454 lrp_1; Leucine-responsive regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D STH12_03355 lrp_2; Leucine-responsive regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D STH12_03400 lrp_3; Leucine-responsive regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
C LuxR family
D STH12_00237 nreC_1; Oxygen regulatory protein NreC K20918 vpsT; LuxR family transcriptional regulator, positive regulator of biofilm formation
D STH12_01083 csgD_1; CsgBAC operon transcriptional regulatory protein K20918 vpsT; LuxR family transcriptional regulator, positive regulator of biofilm formation
C MarR family
D STH12_00161 ohrR_1; Organic hydroperoxide resistance transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
D STH12_03591 ohrR_2; Organic hydroperoxide resistance transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
C MerR family
D STH12_00956 hmrR; HTH-type transcriptional regulator HmrR K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D STH12_04097 zntR_2; HTH-type transcriptional regulator ZntR K13638 zntR; MerR family transcriptional regulator, Zn(II)-responsive regulator of zntA
C Fur family
D STH12_01065 fur; Ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
C IclR family
C CRP/FNR family
D STH12_02916 crp; cAMP-activated global transcriptional regulator CRP K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D STH12_01479 fnr_1; Fumarate and nitrate reduction regulatory protein K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
D STH12_02577 fnr_2; Anaerobic regulatory protein K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
C Rrf2 family
D STH12_00861 iscR; HTH-type transcriptional regulator IscR K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
D STH12_03711 nsrR; HTH-type transcriptional repressor NsrR K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor
C ArsR family
D STH12_03077 aseR; HTH-type transcriptional repressor AseR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D STH12_00447 ygaV_1; putative HTH-type transcriptional regulator YgaV K22042 hlyU; ArsR family transcriptional regulator, virulence genes transcriptional regulator
D STH12_03689 ygaV_2; putative HTH-type transcriptional regulator YgaV K22042 hlyU; ArsR family transcriptional regulator, virulence genes transcriptional regulator
C XRE family
C PadR family
D STH12_03747 lineage-specific thermal regulator protein K10947 K10947; PadR family transcriptional regulator
C Other families
D STH12_01495 ybbH; putative HTH-type transcriptional regulator YbbH K19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator
D STH12_03271 blaI; Penicillinase repressor K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
D STH12_03892 birA; Bifunctional ligase/repressor BirA K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D STH12_03146 fis; DNA-binding protein Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D STH12_00430 trpR; Trp operon repressor K03720 trpR; TrpR family transcriptional regulator, trp operon repressor
D STH12_00980 DNA-binding transcriptional regulator Nlp K07724 ner; Ner family transcriptional regulator
D STH12_04255 higA; Antitoxin HigA K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D STH12_02067 ntrC_2; Nitrogen assimilation regulatory protein K10941 flrA; sigma-54 dependent transcriptional regulator, flagellar regulatory protein
D STH12_03372 acoR; Acetoin catabolism regulatory protein K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR
D STH12_01763 ntrC_1; Nitrogen assimilation regulatory protein K11908 vasH; sigma-54 dependent transcriptional regulator
D STH12_02437 ntrC_3; Nitrogen assimilation regulatory protein K11908 vasH; sigma-54 dependent transcriptional regulator
D STH12_00252 norR; Anaerobic nitric oxide reductase transcription regulator NorR K12266 norR; anaerobic nitric oxide reductase transcription regulator
D STH12_02713 fhlA; Formate hydrogenlyase transcriptional activator K15836 fhlA; formate hydrogenlyase transcriptional activator
D STH12_03152 cdaR; Carbohydrate diacid regulator K02647 cdaR; carbohydrate diacid regulator
D STH12_02409 helix-turn-helix protein K07727 K07727; putative transcriptional regulator
B Ribbon-helix-helix
C CopG family
C Other families
D STH12_04230 metJ; Met repressor K03764 metJ; MetJ family transcriptional regulator, methionine regulon repressor
D STH12_02568 putA; Bifunctional protein PutA K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
B Other transcription factors
C BglG family
C Others
D STH12_02339 transcriptional regulator BolA K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D STH12_03643 parB; putative chromosome-partitioning protein ParB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D STH12_02031 rfaH; Transcription antitermination protein RfaH K05785 rfaH; transcriptional antiterminator RfaH
D STH12_00202 argR; Arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D STH12_01970 tyrR; Transcriptional regulatory protein TyrR K03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport
D STH12_01599 gcvR; Glycine cleavage system transcriptional repressor K03567 gcvR; glycine cleavage system transcriptional repressor
D STH12_00803 pspF; Psp operon transcriptional activator K03974 pspF; psp operon transcriptional activator
D STH12_00806 pspC; Phage shock protein C K03973 pspC; phage shock protein C
D STH12_01064 rnk; Regulator of nucleoside diphosphate kinase K06140 rnk; regulator of nucleoside diphosphate kinase
D STH12_01333 paiB; Protease synthase and sporulation protein PAI 2 K07734 paiB; transcriptional regulator
D STH12_02254 hypothetical protein K07735 algH; putative transcriptional regulator
D STH12_00301 dksA_1; RNA polymerase-binding transcription factor DksA K06204 dksA; RNA polymerase-binding transcription factor
D STH12_00556 nrdR; Transcriptional repressor NrdR K07738 nrdR; transcriptional repressor NrdR
D STH12_04035 cell division protein MraZ K03925 mraZ; transcriptional regulator MraZ
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 3, 2025
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Classification taken and modified from TRANSFAC 7.0