+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Streptomyces avermitilis</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    SAVERM_7537 cas1; cas1	K15342 cas1; CRISP-associated protein Cas1 
C    SAVERM_7587 cas2; cas2	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
D      SAVERM_7543 cas3; cas3	K07012 cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 5.6.2.4] 
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
D      SAVERM_7542 cse1; cse1	K19123 casA; CRISPR system Cascade subunit CasA 
D      SAVERM_7541 cse2; cse2	K19046 casB; CRISPR system Cascade subunit CasB 
D      SAVERM_7540 cse4; cse4	K19124 casC; CRISPR system Cascade subunit CasC 
D      SAVERM_7539 cas5e; cas5e	K19125 casD; CRISPR system Cascade subunit CasD 
D      SAVERM_7538 cse3; cse3	K19126 casE; CRISPR system Cascade subunit CasE 
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      SAVERM_5536 savM2; putative type II restriction-modification system DNA cytosine-specific methylase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
C    SAVERM_3309 savR1; putative Mrr restriction system protein	K07448 mrr; restriction system protein 
C    SAVERM_1059 savR2; putative Mrr restriction system protein	K07448 mrr; restriction system protein 
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
D      SAVERM_671 hypothetical protein	K07171 mazF; mRNA interferase MazF [EC:3.1.-.-] 
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
D      SAVERM_3205 yoeB; putative txe/YoeB family addiction module toxin	K19158 yoeB; toxin YoeB [EC:3.1.-.-] 
D      SAVERM_3206 yefM; putative PHD family toxin-antitoxin system, antitoxin component	K19159 yefM; antitoxin YefM 
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      SAVERM_6124 ftsZ; putative cell division GTPase FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      SAVERM_5455 mreB1; putative rod shape-determining protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      SAVERM_5720 mreB2; putative rod shape-determining protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      SAVERM_2691 gltS; putative glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    SAVERM_2933 dndA; putative DNA modification (L-cysteine desulfurase: pyridoxal phosphate-dependent	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    SAVERM_2756 putative pyridoxal-phosphate-dependent aminotransferase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    SAVERM_2931 dndC; putative DNA modification (sulfurtransferase)	K19170 dndC; DNA sulfur modification protein DndC 
C    SAVERM_2926 hypothetical protein	K19171 dndD; DNA sulfur modification protein DndD 
C    SAVERM_2930 dndD; putative DNA modification (ATPase)	K19171 dndD; DNA sulfur modification protein DndD 
C    SAVERM_2929 dndE; putative DNA modification (phosphoribosylaminoimidazole carboxylase)	K19172 dndE; DNA sulfur modification protein DndE 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023