+C Peptidases and inhibitors KO #

  Peptidases and Inhibitors - Streptomyces malaysiensis DSM 4137

% ! AAspartic peptidases B Family A1: pepsin family B Family A2: retropepsin family B Family A5: thermopsin family B Family A8: signal peptidase II family C SMALA_2006 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] B Family A22: presenilin family B Family A24: type IV prepilin peptidase family C SMALA_4867 type IV peptidase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] B Family A25: gpr protease family B Family A26: omptin family B Family A28 B Family A31: HybD endopeptidase family C SMALA_7419 hydrogenase maturation protease K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-] B Family A36 # ACysteine peptidases B Family C1: papain family B Family C2: calpain family B Family C3: picornain family B Family C4: NIa protease family B Family C5 B Family C9 B Family C10: streptopain family B Family C11: clostripain family B Family C12: ubiquitin C-terminal hydrolase family B Family C13: legumain family B Family C14: caspase family C SMALA_6910 peptidase C14, caspase catalytic subunit P20 K22684 MCA1; metacaspase-1 [EC:3.4.22.-] B Family C15: pyroglutamyl peptidase I family C SMALA_0696 pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] B Family C16 B Family C19: ubiquitin-specific protease family B Family C25: gingipain family B Family C26: gamma-glutamyl hydrolase family C SMALA_1667 glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C SMALA_3371 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C SMALA_6370 putative peptidase K07010 K07010; putative glutamine amidotransferase B Family C27 B Family C30 B Family C37 B Family C39 C SMALA_2971 bacteriocin/lantibiotic ABC transporter K20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter B Family C40 C SMALA_2068 NLP/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SMALA_2069 NLP/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SMALA_3354 NLP/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SMALA_3357 NLP/P60-family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SMALA_4214 NLP/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SMALA_4360 NLP/P60-family protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C SMALA_5264 NLP/P60 family secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] B Family C44 C SMALA_4132 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C SMALA_1959 putative ferredoxin-dependent glutamate synthase 1 K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] C SMALA_2814 glucosamine-fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C SMALA_4491 glucosamine--fructose-6-phosphate aminotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C SMALA_5199 glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C SMALA_7550 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] C SMALA_8331 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] B Family C45 C SMALA_6283 hypothetical protein K19200 IAL; isopenicillin-N N-acyltransferase like protein B Family C46: hedgehog family B Family C47: staphopain family B Family C48: Ulp1 endopeptidase family B Family C50: separase family B Family C54: Aut2 peptidase family B Family C55: YopJ protease family B Family C56: PfpI endopeptidase family C SMALA_3092 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124] C SMALA_6128 intracellular protease/amidase K05520 yhbO; deglycase [EC:3.5.1.124] B Family C57: vaccinia virus I7 peptidase family B Family C58 B Family C59 B Family C60 C SMALA_3917 putative sortase K07284 srtA; sortase A [EC:3.4.22.70] C SMALA_3920 integral membrane protein K07284 srtA; sortase A [EC:3.4.22.70] B Family C63 B Family C64 B Family C65 B Family C67 B Family C69 B Family C70 B Family C75 B Family C76 B Family C78 B Family C79 B Family C82 B Family C83 B Family C85 B Family C86 B Family C88 B Family C89 B Family C97 B Family C98 B Family C110 # AGlutamic peptidases B Family G1 B Family G4 B Family G5: prenyl protease 2 family C SMALA_1015 abortive infection protein K07052 K07052; CAAX protease family protein # AMetallo peptidases B Family M1 C SMALA_1947 aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2] C SMALA_2642 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] C SMALA_2646 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] B Family M2 B Family M3 B Family M4: thermolysin family B Family M5: mycolysin family B Family M6: immune inhibitor A family C SMALA_2984 secreted protease K09607 ina; immune inhibitor A [EC:3.4.24.-] B Family M7: snapalysin family C SMALA_5219 putative secreted extracellular small neutral protease K01416 snpA; snapalysin [EC:3.4.24.77] C SMALA_7009 extracellular small neutral protease K01416 snpA; snapalysin [EC:3.4.24.77] B Family M8: leishmanolysin family B Family M9 B Family M10 B Family M12: astacin/adamalysin family B Family M13: neprilysin family B Family M14: carboxypeptidase A family C SMALA_4849 peptidase M14 carboxypeptidase A K05996 cpt; carboxypeptidase T [EC:3.4.17.18] B Family M15: zinc D-Ala-D-Ala carboxypeptidase family C SMALA_8140 muramoyl-pentapeptide carboxypeptidase K08640 E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C SMALA_0671 D-alanyl-D-alanine dipeptidase (putative secreted protein) K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] C SMALA_5061 putative cell-wall-binding dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] B Family M16: pitrilysin family B Family M17: leucyl aminopeptidase family C SMALA_2102 putative cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] B Family M18 B Family M19: membrane dipeptidase family C SMALA_3156 membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] C SMALA_6151 membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] C SMALA_6991 putative dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] B Family M20 C SMALA_5091 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C SMALA_8092 acetylornithine deacetylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C SMALA_0783 hypothetical protein K23980 tpdA; cysteinylglycine-S-conjugate dipeptidase [EC:3.4.13.23] B Family M23 B Family M24 C SMALA_2189 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C SMALA_2836 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C SMALA_4468 methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C SMALA_3804 Xaa-Pro aminopeptidase II K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] B Family M26 B Family M27 B Family M28: aminopeptidase Y family C SMALA_4385 aminopeptidase Y K19702 E3.4.11.24; aminopeptidase S [EC:3.4.11.24] C SMALA_6876 aminopeptidase Y K19702 E3.4.11.24; aminopeptidase S [EC:3.4.11.24] B Family M29: aminopeptidase T family B Family M32: carboxypeptidase Taq family B Family M34: anthrax lethal factor family B Family M35: deuterolysin family B Family M36: fungalysin family B Family M38: beta-aspartyl dipeptidase family B Family M41: FtsH endopeptidase family C SMALA_3583 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] B Family M42: glutamyl aminopeptidase family B Family M43: cytophagalysin family B Family M44 B Family M48: Ste24 endopeptidase family C SMALA_3828 heat shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] C SMALA_4404 heat shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] B Family M49: dipeptidyl-peptidase III family B Family M50: S2P protease family B Family M54 B Family M55: DppA aminopeptidase family C SMALA_6111 D-aminopeptidase K16203 dppA1; D-amino peptidase [EC:3.4.11.-] B Family M56 C SMALA_0826 integral membrane protein K02172 blaR1; bla regulator protein blaR1 C SMALA_7291 putative membrane-bound protease K02172 blaR1; bla regulator protein blaR1 B Family M67 B Family M72 B Family M73 B Family M74 B Family M80 B Family M82 C SMALA_4183 putative integral membrane protein K24131 prsW; protease PrsW [EC:3.4.-.-] B Family M85 B Family M88 B Family M90 B Family M98 # AAsparagine peptide lyases B Family N1 B Family N8 # AMixed peptidases B Family P1: DmpA aminopeptidase family B Family P2 # ASerine peptidases B Family S1: chymotrypsin family C SMALA_3797 putative serine protease K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C SMALA_4250 serine protease K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C SMALA_5102 protease K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C SMALA_0457 serine protease precursor K18545 sprB; streptogrisin B [EC:3.4.21.81] C SMALA_1687 serine protease precursor K18545 sprB; streptogrisin B [EC:3.4.21.81] C SMALA_6171 secreted serine protease K18546 sprC; streptogrisin C [EC:3.4.21.-] C SMALA_7004 putative secreted serine protease K18546 sprC; streptogrisin C [EC:3.4.21.-] C SMALA_0182 protease precursor K18547 sprD; streptogrisin D [EC:3.4.21.-] C SMALA_0192 secreted protease K18547 sprD; streptogrisin D [EC:3.4.21.-] C SMALA_1685 serine protease precursor K18547 sprD; streptogrisin D [EC:3.4.21.-] C SMALA_7191 serine protease precursor K18547 sprD; streptogrisin D [EC:3.4.21.-] B Family S3: togavirin family B Family S6 B Family S7: flavivirin family B Family S8: subtilisin family C SMALA_5635 putative secreted subtilisin-like serine protease K14743 mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-] B Family S9: prolyl oligopeptidase family C SMALA_5076 peptidase S9 prolyl oligopeptidase active site domain protein K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] B Family S10 B Family S11: D-Ala-D-Ala carboxypeptidase A family C SMALA_0563 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SMALA_0887 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SMALA_3308 putative D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SMALA_4309 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C SMALA_4593 D-alanyl-D-alanine carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] B Family S12: D-Ala-D-Ala carboxypeptidase B family B Family S13: D-Ala-D-Ala peptidase C family C SMALA_0890 carboxypeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] C SMALA_3058 penicillin binding protein K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] C SMALA_3587 D-alanyl-D-alanine carboxypeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] B Family S14: ClpP endopeptidase family C SMALA_2323 putative ATP-dependent Clp protease proteolytic subunit 2 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SMALA_2324 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SMALA_2620 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SMALA_2621 endopeptidase Clp K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C SMALA_6874 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] B Family S15 C SMALA_6317 x-prolyl-dipeptidyl aminopeptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11] C SMALA_7261 x-prolyl-dipeptidyl aminopeptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11] B Family S16: lon protease family C SMALA_5254 ATP-dependent protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] C SMALA_2998 secreted protein K07177 K07177; Lon-like protease C SMALA_5155 secreted protein K07177 K07177; Lon-like protease B Family S21: assemblin family B Family S24: LexA family C SMALA_5718 transcriptional repressor, LexA family K01356 lexA; repressor LexA [EC:3.4.21.88] B Family S26: signal peptidase I family C SMALA_5566 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C SMALA_5567 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C SMALA_5568 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C SMALA_5569 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] B Family S28 B Family S31 B Family S32 B Family S33 C SMALA_3008 putative hydrolase K01259 pip; proline iminopeptidase [EC:3.4.11.5] C SMALA_8300 putative proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] C SMALA_4619 epoxide hydrolase K27108 ephA_B; epoxide hydrolase A/B [EC:3.3.2.-] B Family S41: C-terminal processing peptidase family C SMALA_3070 carboxy-terminal processing protease precursor K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] C SMALA_4704 protease K08676 tri; tricorn protease [EC:3.4.21.-] B Family S45 C SMALA_4686 peptidase S45, penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11] B Family S49: protease IV family B Family S50 B Family S51 C SMALA_5414 peptidase E K05995 pepE; dipeptidase E [EC:3.4.13.21] B Family S53 B Family S54: Rhomboid family C SMALA_2072 integral membrane protein K07059 rho2; rhomboid family protease [EC:3.4.21.105] B Family S55: SpoIVB peptidase family B Family S62 B Family S66 B Family S77: phage prohead processing peptidase family B Family S78 # AThreonine peptidases B Family T1: proteasome family C SMALA_1431 20S proteasome alpha-subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] C SMALA_1432 20S proteasome beta-subunit precursor K03433 psmB; proteasome beta subunit [EC:3.4.25.1] B Family T2 B Family T3: gamma-glutamyltransferase family C SMALA_4782 putative gamma-glutamyl transferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] C SMALA_6067 putative gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] # APeptidases of unknown catalytic type B Family U32 B Family U62 C SMALA_1776 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein # APeptidase inhibitors B Family I1: Kazal family B Family I2: Kunitz - BPTI family B Family I4: serpin family B Family I11: ecotin family B Family I17: WAP-type family B Family I25: cystatin family B Family I27: calpastatin family B Family I32: IAP family B Family I34: IA3 family B Family I35: timp family B Family I39: alpha2M family B Family I47: latexin family B Family I49: proSAAS family B Family I51: IC family B Family I57: staphostatin B family B Family I63 B Family I80 B Family I87 B Family I93 ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 20, 2025 #
Classification taken and modified from MEROPS