+F Repair protein KO #

  DNA Repair and Recombination Proteins - Streptomyces mirabilis

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AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D SMIR_03695 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D SMIR_29325 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D SMIR_38030 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E SMIR_33280 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E SMIR_35000 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E SMIR_30420 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E SMIR_15955 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E SMIR_16520 nth; (GenBank) endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E SMIR_20725 DEAD/DEAH box helicase K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D SMIR_04990 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_12295 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_19920 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_26935 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_07980 dut; (GenBank) dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D SMIR_03695 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D SMIR_29325 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D SMIR_38030 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D SMIR_35660 alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33] C BER (base exicision repair) D DNA glycosylases E SMIR_33280 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E SMIR_35000 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E SMIR_33865 mug; (GenBank) G/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28] E SMIR_29165 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E SMIR_03700 DNA-3-methyladenine glycosylase 2 family protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E SMIR_06370 helix-turn-helix domain-containing protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E SMIR_30420 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E SMIR_15955 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E SMIR_12070 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E SMIR_09585 mutM; (GenBank) bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E SMIR_08630 Fpg/Nei family DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E SMIR_25230 Fpg/Nei family DNA glycosylase K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E SMIR_16520 nth; (GenBank) endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E SMIR_04290 xth; (GenBank) exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] E SMIR_21955 xth; (GenBank) exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] E SMIR_28390 deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] E SMIR_01085 endonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7] D RecJ D DNA ligase E SMIR_10125 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E SMIR_34925 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E SMIR_41660 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E SMIR_29075 polA; (GenBank) DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E SMIR_02065 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A E SMIR_29400 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A E SMIR_29340 uvrB; (GenBank) excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B E SMIR_29425 uvrC; (GenBank) excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C E SMIR_11825 ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SMIR_11845 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SMIR_14025 pcrA; (GenBank) DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SMIR_29075 polA; (GenBank) DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E SMIR_10125 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E SMIR_34925 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E SMIR_41660 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F SMIR_14755 rpoB; (GenBank) DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F SMIR_14750 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F SMIR_14485 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F SMIR_32570 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F SMIR_22360 mfd; (GenBank) transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases E SMIR_12415 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E SMIR_12420 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E SMIR_28645 dnaE; (GenBank) DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E SMIR_36850 dnaE; (GenBank) DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E SMIR_13355 dnaN; (GenBank) DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E SMIR_18565 dnaN; (GenBank) DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E SMIR_25645 holA; (GenBank) DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E SMIR_16375 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E SMIR_07015 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E SMIR_30195 DEDDh family exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E SMIR_19470 DNA polymerase III subunit gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E SMIR_10125 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E SMIR_34925 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E SMIR_41660 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E SMIR_11825 ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SMIR_11845 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SMIR_14025 pcrA; (GenBank) DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SMIR_18710 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E SMIR_24755 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E SMIR_23815 very short patch repair endonuclease K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-] B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E SMIR_24580 ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E SMIR_33530 ATP-dependent RecD-like DNA helicase K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E SMIR_08585 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA E SMIR_32355 ruvA; (GenBank) Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA E SMIR_32360 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E SMIR_32350 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E SMIR_32585 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E SMIR_33760 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 E SMIR_33755 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 D RecFOR pathway proteins E SMIR_08585 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA E SMIR_15940 radA; (GenBank) DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms E SMIR_18555 recF; (GenBank) DNA replication/repair protein RecF K03629 recF; DNA replication and repair protein RecF E SMIR_09620 recG; (GenBank) ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E SMIR_25990 recO; (GenBank) DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E SMIR_16845 recR; (GenBank) recombination mediator RecR K06187 recR; recombination protein RecR E SMIR_30495 recN; (GenBank) DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) E SMIR_32355 ruvA; (GenBank) Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA E SMIR_32360 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E SMIR_32350 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins E SMIR_33760 SMC family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 E SMIR_33755 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 E SMIR_19390 DUF853 family protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex E SMIR_11175 Ku protein K10979 ku; DNA end-binding protein Ku E SMIR_11180 ligD; (GenBank) non-homologous end-joining DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F SMIR_08105 DNA topoisomerase IV subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F SMIR_18540 gyrA; (GenBank) DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F SMIR_08195 type IIA DNA topoisomerase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F SMIR_18545 gyrB; (GenBank) DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F SMIR_16385 topA; (GenBank) type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F SMIR_09695 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta F SMIR_23355 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta F SMIR_42870 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F SMIR_25990 recO; (GenBank) DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F SMIR_16845 recR; (GenBank) recombination mediator RecR K06187 recR; recombination protein RecR F SMIR_10125 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] F SMIR_34925 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] F SMIR_41660 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F SMIR_08240 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F SMIR_15130 recQ; (GenBank) DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F SMIR_02065 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A F SMIR_29400 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A F SMIR_29340 uvrB; (GenBank) excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D SMIR_33150 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D SMIR_08585 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA D SMIR_08300 lexA; (GenBank) transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D SMIR_43015 lexA; (GenBank) transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D SMIR_30495 recN; (GenBank) DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D SMIR_30780 DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D SMIR_41820 DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D SMIR_18710 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SMIR_24755 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SMIR_08580 recX; (GenBank) recombination regulator RecX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D SMIR_42995 ATP-dependent helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4] D SMIR_08305 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D SMIR_05025 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] D SMIR_08625 ATP-dependent helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D SMIR_04990 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_12295 (deoxy)nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_19920 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_26935 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SMIR_30525 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D SMIR_07980 dut; (GenBank) dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D SMIR_08290 vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SMIR_11600 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SMIR_11605 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025