+D Transcription factors KO #

  Transcription Factors - Schistosoma mansoni

% ! AEukaryotic type B Basic leucine zipper (bZIP) C AP-1(-like) components, Jun D Smp_044770 hypothetical protein K09027 XBP1; X box-binding protein 1 C AP-1(-like) components, Fos C AP-1(-like) components, Maf C AP-1(-like) components, NF-E2 D Smp_011860 putative transcription factor LCR-F1 K09040 NFE2L1_3; nuclear factor erythroid 2-related factor 1/3 C AP-1(-like) components, Fungal regulators C AP-1(-like) components, CRE-BP/ATF D Smp_080420 hypothetical protein K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2 C CREB D Smp_151280.1 camp-response element binding protein-related K09048 CREB3; cyclic AMP-responsive element-binding protein 3 C C/EBP-like factors C bZIP/PAR C Plant bZIP factors C ZIP only B Basic helix-loop-helix (bHLH) C Ubiquitous (class A) factors D Smp_142270 basic helix-loop-helix transcription factor,putative K15603 TCF4_12; transcription factor 4/12 C Myogenic transcription factors C Achaete-Scute D Smp_142120 achaete-scute transcription factor-related K09067 ASCL; achaete-scute complex protein C Tal/Twist/Atonal/Hen, Lymphoid factors C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors D Smp_062490 putative dhand K18486 HAND2; heart-and neural crest derivatives-expressed protein 2 D Smp_136120 putative n-twist K09073 PTF1A; pancreas-specific transcription factor 1a C Tal/Twist/Atonal/Hen, HEN C Tal/Twist/Atonal/Hen, Mesp C Tal/Twist/Atonal/Hen, Atonal D Smp_072470 neurogenic differentiation factor K08033 NEUROD1; neurogenic differentiation factor 1 D Smp_125400 neurogenin K08033 NEUROD1; neurogenic differentiation factor 1 D Smp_067430 basic helix-loop-helix protein, putative K09085 BHLHB1_6_7; class B basic helix-loop-helix protein 1/6/7 C Tal/Twist/Atonal/Hen, Pancreatic factors D Smp_000620 hypothetical protein K09086 BHLHB4_5; class B basic helix-loop-helix protein 4/5 C Hairy, Hairy/E(SPL) D Smp_152190 basic helix-loop-helix transcription factor,hes-related K09090 HESN; hairy and enhancer of split, invertebrate C Hairy, Fungal regulators C Factors with PAS domain D Smp_123420 aryl hydrocarbon receptor nuclear translocator homolog (darnt), putative K09097 ARNT; aryl hydrocarbon receptor nuclear translocator D Smp_178780 meso-ectoderm gene expression control protein K09100 SIM; single-minded C Yabby C INO C HLH domain only D Smp_155360 putative dna-binding protein inhibitor K17696 EMC; DNA-binding protein inhibitor ID, other D Smp_194660 hypothetical protein K09103 EBF; early B-cell factor D Smp_194670 hypothetical protein K09103 EBF; early B-cell factor B Basic helix-loop-helix/leucine zipper (bHLH-ZIP) C Ubiquitous bHLH-ZIP factors D Smp_160710 putative upstream stimulatory factor K09455 MITF; microphthalmia-associated transcription factor D Smp_103540.1 activator protein 4 (ap4), putative K09108 TFAP4; transcription factor AP-4 C Cell cycle controlling factors, Myc C Cell cycle controlling factors, Mad/Max D Smp_142400.1 putative bhlhzip transcription factor bigmax K09113 MLX; MAX-like protein X D Smp_162080 hypothetical protein K09113 MLX; MAX-like protein X D Smp_021340.1 Mxi neural development protein K09114 MXD; MAX dimerization protein C Other bHLH-ZIP factors B Other basic domains C NF-1 C RF-X D Smp_170910 putative rfx transcription factor K09173 RFX1_2_3; regulatory factor X 1/2/3 D Smp_040350 putative rfx5 K09175 RFX7; DNA-binding protein RFX7 C AP-2 (bHSH) B Zinc finger C Cys4 thyroid hormone receptor-like D Smp_000340 nuclear hormone receptor superfamily protein-related K08701 NR1D3; nuclear receptor subfamily 1 group D member 3 D Smp_144170 RAR-like nuclear receptor K08532 NR1F1; RAR-related orphan receptor alpha C Cys4 hepatocyte nuclear factor 4-like D Smp_174700 putative hepatocyte nuclear factor 4-alpha (hnf-4-alpha) K08704 NR2A4; hepatocyte nuclear factor 4 D Smp_097700 retinoic acid receptor RXR K08524 RXRA; retinoid X receptor alpha D Smp_155250 putative zinc finger protein K08545 NR2E1; nuclear receptor subfamily 2 group E member 1 D Smp_167770 photoreceptor-specific nuclear receptor related K08546 NR2E3; nuclear receptor subfamily 2 group E member 3 C Cys4 estrogen receptor-like C Cys4 nerve growth factor IB-like D Smp_139200 nuclear hormone receptor nor-1/nor-2, putative K08558 NR4A2; nuclear receptor subfamily 4 group A member 2 C Cys4 Fushi tarazu-F1-like D Smp_068780 FTZ-F1 nuclear receptor-like protein K08705 NR5A3; nuclear receptor subfamily 5 group A member 3 C Cys4 germ cell nuclear factor C Cys4 Knirps/DAX1-like C Cys4 GATA-factors D Smp_159560 putative gata binding factor K09182 GATA1; GATA-binding protein 1 D Smp_018590 putative gata binding factor K17895 GATA3; GATA-binding protein 3 D Smp_175500 putative gata binding factor K09184 GATAF; GATA-binding protein, other eukaryote D Smp_049730.1 putative metastasis-associated protein 1 (mta1) K11660 MTA; metastasis-associated protein MTA D Smp_168850.1 metastasis-associated protein 1 (mta1),putative K11660 MTA; metastasis-associated protein MTA D Smp_153820 putative transcriptional regulator atrx homolog (X-linked nuclear protein-1) K10779 ATRX; transcriptional regulator ATRX C Cys2His2 SP/KLF family and related proteins D Smp_018170 putative zinc finger protein K09207 KLF6_7; krueppel-like factor 6/7 D Smp_172460 hypothetical protein K09209 KLF10_11; krueppel-like factor 10/11 D Smp_026270 putative early growth response protein K09203 EGR1; early growth response protein 1 D Smp_094930 early growth response protein, putative K09203 EGR1; early growth response protein 1 D Smp_134870 putative early growth response protein K09203 EGR1; early growth response protein 1 C Cys2His2 GLI-like D Smp_000530 zinc finger transcription factor gli2 K16799 CI; transcriptional activator cubitus interruptus C Cys2His2 Snail D Smp_068240 putative zinc finger protein K05706 SNAI2; snail 2 D Smp_155070 putative zinc finger protein K05706 SNAI2; snail 2 D Smp_054430 putative zinc finger protein K09219 SCRT; scratch D Smp_172430 insulinoma-associated protein (ia-1)-related K25795 INSM; insulinoma-associated protein C Cys2His2 BTB-ZF factors C Cys2His2 BED C Cys2His2 PRDM D Smp_128350 hypothetical protein K24501 PRDM1; PR domain zinc finger protein 1 [EC:2.1.1.-] D Smp_005520.1 zinc finger protein, putative K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-] C Cys2His2 metabolic regulators in fungi C Cys2His2 others D Smp_175410 zinc-finger domain containing protein K09223 GFI1; growth factor independent 1 D Smp_066430 ae-1 binding protein aebp2, putative K17452 AEBP2; zinc finger protein AEBP2 D Smp_124090 putative b-cell lymphoma/leukemia K22046 BCL11B; B-cell lymphoma/leukemia 11B D Smp_138350 hypothetical protein K24146 BNC; zinc finger protein basonuclin D Smp_023990 putative transcriptional repressor protein yy (yin and yang) (delta transcription factor) K09201 YY; transcription factor YY D Smp_121800 putative replication factor A 1, rfa1 K07466 RFA1; replication factor A1 D Smp_169260 putative zinc finger protein K23480 ZNF362_384; zinc finger protein 362/384 D Smp_160440 putative zinc finger protein K09228 KRAB; KRAB domain-containing zinc finger protein D Smp_160730 putative zinc finger protein K09228 KRAB; KRAB domain-containing zinc finger protein D Smp_174800 putative zinc finger protein K09228 KRAB; KRAB domain-containing zinc finger protein D Smp_144540 putative c2h2 zinc finger protein K24502 FEZF; Fez family zinc finger protein D Smp_101310 Mizf protein, putative K25794 HINFP; histone H4 transcription factor D Smp_128060 hypothetical protein K19871 SALL; sal-like protein D Smp_135380 putative hunchback protein K09213 HB; hunchback C Cys2HisCys zinc factors D Smp_194520 putative myst histone acetyltransferase K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48] D Smp_198670 putative myst histone acetyltransferase K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48] D Smp_053140 tip60, putative K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48] D Smp_150840.1 hypothetical protein K15263 LYER; cell growth-regulating nucleolar protein C Cys3His zinc factors D Smp_204730 unnamed protein product K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] C Cys2CysHis zinc factors C CXXC CpG-binding proteins D Smp_022020.1 putative cpg binding protein K14960 CXXC1; COMPASS component SPP1 D Smp_152520 putative cpg binding protein K14960 CXXC1; COMPASS component SPP1 D Smp_127230 phd/f-box containing protein, putative K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] C Cys6 metabolic regulators in fungi C Other zinc fingers D Smp_156020 putative glucose transporter K12236 NFX1; transcriptional repressor NF-X1 D Smp_179300.1 putative cellular nucleic acid binding protein K09250 CNBP; cellular nucleic acid-binding protein D Smp_012150 hypothetical protein K24369 ZC4H2; zinc finger C4H2 domain-contaning protein D Smp_123810 hypothetical protein K22383 IRF2BP; interferon regulatory factor 2-binding protein B Helix-turn-helix C Homeo domain ANTP: HOXL D Smp_081620 gsx family homeobox protein K09304 HOX_4; homeobox protein HoxA/B/C/D4 D Smp_126190 homeobix protein hb9 mnx2, putative K08025 HLXB9; homeobox protein HB9 C Homeo domain ANTP: NKL D Smp_137140 putative nk homeobox protein K09309 NKX1; homeobox protein Nkx-1 D Smp_013600 putative nk homeobox protein K09349 NKX5; homeobox protein Nkx-5 D Smp_126870 putative nk-6 homeobox protein K08030 NKX6-1; homeobox protein Nkx-6.1 D Smp_134690 putative emx homeobox protein K09317 EMX; homeobox protein EMX D Smp_145200 putative engrailed K09319 EN; homeobox protein engrailed D Smp_144380 msx family homeobox protein K09341 MSX; homeobox protein MSX C Homeo domain Paired-related D Smp_035650 homeobox protein aristaless-related K09326 OTX1; homeobox protein OTX1 D Smp_175710 homeobox protein aristaless-related K09328 UNC4; homeobox protein Unc-4 D Smp_000830 homeobox protein smox-3 K09330 PHOX2; paired mesoderm homeobox protein 2 D Smp_091160 putative retinal homeobox protein K09332 RAX; retina and anterior neural fold homeobox protein D Smp_140350 omeobox protein aristaless-related K09332 RAX; retina and anterior neural fold homeobox protein D Smp_017020 homeobox protein vsx-1-related K09336 VSX2; visual system homeobox protein 2 D Smp_126560 putative orthopedia homeobox protein K24901 OTP; homeobox protein orthopedia D Smp_142940 putative paired box protein pax-6 K15608 PAX2; paired box protein 2 D Smp_170750 putative paired box protein pax-6 K08031 PAX6; paired box protein 6 C Homeo domain LIM D Smp_148570 lim homeobox protein,putative K09371 LMX1; LIM homeobox transcription factor 1 D Smp_129480 putative lim homeobox protein K09372 LHX1; LIM homeobox protein 1 D Smp_079260 putative lim homeobox protein K09373 LHX2_9; LIM homeobox protein 2/9 D Smp_165410 putative lhx3 K09374 LHX3_4; LIM homeobox protein 3/4 D Smp_144120 putative lim/homeobox protein Awh (Protein arrowhead) K09375 LHX6_8; LIM homeobox protein 6/8 D Smp_087250 putative crp1/csrp1/crip1 K09377 CSRP; cysteine and glycine-rich protein D Smp_162190 crp-related K09377 CSRP; cysteine and glycine-rich protein C Homeo domain POU D Smp_122920 putative pou Transcription factor K09364 POU2F; POU domain transcription factor, class 2 D Smp_000690 pou4/brn-3, putative K09366 POU4F; POU domain transcription factor, class 4 D Smp_009040 putative pou4/brn-3 K09366 POU4F; POU domain transcription factor, class 4 D Smp_139940 putative pou6f1/brn-5 K09368 POU6F; POU domain transcription factor, class 6 C Homeo domain SINE C Homeo domain ZF D Smp_166560 transcription factor, putative K23560 ZEB2; zinc finger homeobox protein 2 C Homeo domain CUT D Smp_049990 casp, putative K09313 CUTL; homeobox protein cut-like D Smp_013070 putative one cut domain family member K08026 ONECUT1; one cut domain, family member 1 (hepatocyte nuclear factor 6) C Homeo domain PROS D Smp_045470 homeobox protein prospero/prox-1/ceh-26,putative K20211 PROX1; prospero homeobox 1 D Smp_162760 prospero-like protein K20211 PROX1; prospero homeobox 1 C Homeo domain TALE D Smp_126030 putative pre-B-cell leukemia transcription factor 1, 2,3, 4 (pbx) K09355 PBX1; pre-B-cell leukemia transcription factor 1 D Smp_149230 iroquois homeobox family transcription factor K24889 IRX; iroquois-class homeodomain protein IRX C Homeo domain other C Fork head/winged helix developmental regulators D Smp_158750 putative forkhead protein/ forkhead protein domain K09396 FOXC; forkhead box protein C D Smp_150430 putative forkhead protein/ forkhead protein domain K09385 FOXG; forkhead box protein G C Fork head/winged helix tissue-specific regulators C Fork head/winged helix cell cycle-controlling factors, E2F D Smp_093310 E2F/DP family, putative K04682 E2F4_5; transcription factor E2F4/5 C Fork head/winged helix cell cycle-controlling factors, DP D Smp_210520 putative tyrosyl-DNA phosphodiesterase K04683 TFDP1; transcription factor Dp-1 C Fork head/winged helix other regulators D Smp_054350 putative forkhead protein/ forkhead protein domain K09397 FOXD; forkhead box protein D D Smp_155010 forkhead protein/ forkhead protein domain,putative K09403 FOXJ2_3; forkhead box protein J2/3 D Smp_135710 putative forkhead protein/ forkhead protein domain K09404 FOXK; forkhead box protein K D Smp_145650 hypothetical protein K09404 FOXK; forkhead box protein K D Smp_012010 hypothetical protein K09408 FOXO3; forkhead box protein O3 C Heat shock factors D Smp_068270.1 putative heat shock transcription factor K09414 HSF1; heat shock transcription factor 1 C Tryptophan clusters Myb, Myb-factors C Tryptophan clusters Myb, Myb-like factors D Smp_101370.1 mesoderm induction early response 1 related K28169 MIER1; mesoderm induction early response protein 1 C Tryptophan clusters Ets-type D Smp_127020 putative ets K09431 ETV1; ets translocation variant 1 D Smp_126530 putative ets K21932 ETS2; C-ets-2 D Smp_051130 ets-related K09436 FLI1; friend leukemia integration 1 transcription factor D Smp_128330 ets-related K09436 FLI1; friend leukemia integration 1 transcription factor D Smp_168810 ets, putative K09441 GABPA; GA-binding protein transcription factor, alpha C Tryptophan clusters interferon-regulating factors D Smp_071470 hypothetical protein K09445 IRF4; interferon regulatory factor 4 C TEA domain D Smp_066050 transcriptional enhancer factor (tef) related K09448 TEAD; transcriptional enhancer factor D Smp_141830 transcriptional enhancer factor (tef) related K09448 TEAD; transcriptional enhancer factor C ARID D Smp_156170 hypothetical protein K11653 ARID1; AT-rich interactive domain-containing protein 1 D Smp_157150 hypothetical protein K11765 ARID2; AT-rich interactive domain-containing protein 2 D Smp_135110 putative at-rich interactive domain 3, arid3 K25856 ARID3; AT-rich interactive domain-containing protein 3 B beta-Scaffold factors with minor groove contacts C RHR (Rel homology region) Rel/Ankyrin C RHR (Rel homology region) Ankyrin only D Smp_160500 nalp (nacht, leucine rich repeat and pyrin domain containing)-related K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2 D Smp_079700 putative ga binding protein beta chain (transcription factor e4tf1-47) K09454 GABPB; GA-binding protein transcription factor, beta C RHR (Rel homology region) NF-AT C STAT C p53 D Smp_139530 cellular tumor antigen P53, putative K10149 TP63; tumor protein p63 C MADS-box regulators of differentiation, MEF-2 D Smp_129430 putative myocyte-specific enhancer factor 2a K09260 MEF2A; MADS-box transcription enhancer factor 2A C MADS-box regulators of differentiation, Homeotic genes C MADS-box regulators of differentiation, Yeast regulators C MADS-box responders to external signals D Smp_097730 srf homolog, putative K04378 SRF; serum response factor C SAND domain-containing proteins C TATA-binding proteins D Smp_073680.1 putative tata-box binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Smp_087520 TATA-binding protein-related K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein D Smp_098950 TATA-box binding protein, putative K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein C HMG SOX D Smp_155690 sox transcription factor K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B) D Smp_161600 sox transcription factor K09269 SOX5_6_13; transcription factor SOX5/6/13 (SOX group D) D Smp_142600 putative capicua protein K20225 CIC; capicua transcriptional repressor C HMG TCF-1 D Smp_125630 pangolin, putative K04491 TCF7L2; transcription factor 7-like 2 D Smp_148190 putative t-cell specific transcription factor, tcf K04491 TCF7L2; transcription factor 7-like 2 C HMG2-related D Smp_148930 structure specific recognition protein,putative K09272 SSRP1; FACT complex subunit SSRP1/POB3 C UBF C Other HMG box factors C Heteromeric CCAAT factors D Smp_030250 NF-YA subunit K08064 NFYA; nuclear transcription factor Y, alpha D Smp_154340 putative nuclear factor Y transcription factor subunit B homolog K08065 NFYB; nuclear transcription Y subunit beta D Smp_176340 CCAAT-binding transcription factor, putative K08066 NFYC; nuclear transcription factor Y, gamma C Grainyhead D Smp_019040 putative transcription factor lbp1,cp2 K09275 TFCP2; transcription factor CP2 and related proteins C Cold-shock domain factors, DbpA-like C Cold-shock domain factors, YB-1/DbpB-like D Smp_097750 cold shock domain protein A, putative K09276 YBX1; Y-box-binding protein 1 D Smp_097800.1 Y box binding protein, putative K09276 YBX1; Y-box-binding protein 1 C Cold-shock domain factors, FRG Y2-like C Runt C MYRF B Other transcription factors C HMGI(Y) C NUPR C Pocket domain Rb D Smp_024900 putative retinoblastoma-like protein K16332 RBL2; retinoblastoma-like protein 2 C Pocket domain CBP D Smp_105910 CREB-binding protein 1 (SmCBP1) K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48] D Smp_127010 putative creb-binding protein 2 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48] C T-box D Smp_163240 putative T-box transcription factor tbx2 K10176 TBX2; T-box protein 2 D Smp_145230 putative t-box protein K10177 TBX3; T-box protein 3 C DMRT D Smp_132060 doublesex and mab-3 related transcription factor K19489 DMRT2; doublesex- and mab-3-related transcription factor 2 C LRRFIP D Smp_175460 hypothetical protein K26434 LRRFIP; leucine-rich repeat flightless-interacting protein C TCP C AP2/ERF C WRKY C LOB C GRAS C Copper-fist proteins fungal regulators C Others D Smp_148400 putative calmodulin-binding transcription activator (camta) K21596 CAMTA; calmodulin-binding transcription activator D Smp_152660 glial cells missing related K21598 GCM; chorion-specific transcription factor GCM D Smp_171130 glial cells missing related K21598 GCM; chorion-specific transcription factor GCM D Smp_104000.1 hypothetical protein K22145 TMEM18; transmembrane protein 18 D Smp_014270 hypothetical protein K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2 D Smp_145970 putative recombining binding protein suppressor of hairless K06053 RBPSUH; recombining binding protein suppressor of hairless D Smp_065810 hypothetical protein K23804 GON4L; GON-4-like protein D Smp_042300.1 PUR-alpha-like protein K21772 PURA; transcriptional activator protein Pur-alpha D Smp_075120 putative pur-alpha K21772 PURA; transcriptional activator protein Pur-alpha D Smp_041480.1 rna recognition motif (rrm) domain containing protein, putative K24992 MYEF2; myelin expression factor 2 D Smp_163180 hypothetical protein K28083 ECD; protein ecdysoneless D Smp_196410 putative dachshund homolog K28157 DACH; dachshund # AProkaryotic type B Helix-turn-helix C AraC family C LysR family C DeoR family C LacI family C GntR family C TetR/AcrR family C Lrp/AsnC family C LuxR family C MarR family C MerR family C Fur family C IclR family C CRP/FNR family C Rrf2 family C ArsR family C XRE family C PadR family C Other families B Ribbon-helix-helix C CopG family C Other families B Other transcription factors C BglG family C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 18, 2025 #
Classification taken and modified from TRANSFAC 7.0