+F Repair protein KO
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DNA Repair and Recombination Proteins - Streptococcus pneumoniae ATCC 700669 (serotype 23F ST81 lineage)
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPN23F14270 ogt; putative methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E SPN23F10720 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPN23F11240 mutY; putative A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPN23F11730 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SPN23F06640 MutT/NUDIX family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F07390 MutT/NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F10710 mutX; mutator MutX protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F11310 MutT/NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F00390 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPN23F14270 ogt; putative methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E SPN23F10720 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPN23F11240 mutY; putative A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPN23F01770 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SPN23F08950 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SPN23F11730 nth; putative endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SPN23F18600 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E SPN23F05510 putative phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SPN23F10380 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SPN23F00490 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SPN23F01820 uvrA; UvrABC system protein A (UvrA protein) K03701 uvrA; excinuclease ABC subunit A
E SPN23F11340 uvrB; UvrABC system protein B (UvrB protein) K03702 uvrB; excinuclease ABC subunit B
E SPN23F05570 uvrC; UvrABC DNA repair system protein C K03703 uvrC; excinuclease ABC subunit C
E SPN23F10080 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPN23F12470 putative DNA helicase II, UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPN23F00490 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SPN23F10380 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SPN23F19820 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SPN23F19810 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SPN23F02240 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SPN23F04480 rpoE; putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F SPN23F17400 rpoZ; DNA-directed RNA polymerase omega chain K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SPN23F00060 trcF; putative putative transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SPN23F21010 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E SPN23F03830 mutS2; putative DNA mismatch repair protein K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E SPN23F01710 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E SPN23F18640 putative restriction enzyme K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E SPN23F11070 xseA; putative exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SPN23F11060 xseB; putative exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SPN23F08170 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SPN23F02600 polC; DNA polymerase III PolC-type K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E SPN23F00020 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SPN23F06870 putative DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SPN23F08580 holB; putative DNA polymerase III, delta' subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SPN23F09180 putative exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SPN23F07880 dnaH; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SPN23F10380 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SPN23F10080 pcrA; putative ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPN23F12470 putative DNA helicase II, UvrD K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SPN23F15030 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
E SPN23F15680 ssb; putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SPN23F19320 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SPN23F03770 conserved hypothetical protein K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E SPN23F19620 recA; RecA recombinase (recombinase A) K03553 recA; recombination protein RecA
E SPN23F01760 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SPN23F02470 ruvB; Holliday junction DNA helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SPN23F15620 putative phage Holliday junction resolvase K01160 rusA; crossover junction endodeoxyribonuclease RusA [EC:3.1.21.10]
E SPN23F17390 priA; putative primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E SPN23F19620 recA; RecA recombinase (recombinase A) K03553 recA; recombination protein RecA
E SPN23F00410 sms; putative DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E SPN23F22600 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E SPN23F16960 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SPN23F05510 putative phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SPN23F00540 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E SPN23F16730 recR; recombination protein RecR K06187 recR; recombination protein RecR
E SPN23F11020 recN; putative DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E SPN23F03420 recU; putative recombination protein U K03700 recU; recombination protein U
E SPN23F01760 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SPN23F02470 ruvB; Holliday junction DNA helicase, subunit B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E SPN23F10550 addA; putative ATP-dependent exonuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E SPN23F10540 addB; putative ATP-dependent exonuclease subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SPN23F11160 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SPN23F07350 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SPN23F11580 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SPN23F10340 hlpA; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SPN23F05510 putative phosphoesterase K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SPN23F00540 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F SPN23F16730 recR; recombination protein RecR K06187 recR; recombination protein RecR
F SPN23F10380 lig; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F SPN23F01820 uvrA; UvrABC system protein A (UvrA protein) K03701 uvrA; excinuclease ABC subunit A
F SPN23F11340 uvrB; UvrABC system protein B (UvrB protein) K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SPN23F04310 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D SPN23F19620 recA; RecA recombinase (recombinase A) K03553 recA; recombination protein RecA
D SPN23F11020 recN; putative DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D SPN23F15030 ssb; single strand binding protein (SSB) K03111 ssb; single-strand DNA-binding protein
D SPN23F15680 ssb; putative single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPN23F19320 putative single stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SPN23F19240 RecX family protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SPN23F07310 putative exonuclease K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D SPN23F06640 MutT/NUDIX family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F07390 MutT/NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F10710 mutX; mutator MutX protein (7,8-dihydro-8-oxoguanine-triphosphatase) K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F11310 MutT/NUDIX hydrolase family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPN23F00390 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SPN23F10810 putative ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SPN23F10820 putative ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D SPN23F11920 conserved hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024