+F Repair protein KO #

  DNA Repair and Recombination Proteins - Streptococcus pneumoniae AP200 (serotype 11A)

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D SPAP_1491 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E SPAP_1045 Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E SPAP_1253 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E SPAP_1304 Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D SPAP_0715 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_0786 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_1046 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_1260 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_1774 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_0073 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D SPAP_1491 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] C BER (base exicision repair) D DNA glycosylases E SPAP_1045 Uracil DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E SPAP_1253 A/G-specific DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E SPAP_0234 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E SPAP_1002 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E SPAP_1304 Predicted EndoIII-related endonuclease K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E SPAP_1838 Exonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] D RecJ E SPAP_0598 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D DNA ligase E SPAP_1076 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E SPAP_0083 DNA polymerase I - 3'-5' exonuclease and polymerase domains K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E SPAP_0239 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A E SPAP_1263 Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B E SPAP_0604 Nuclease subunit of the excinuclease complex K03703 uvrC; excinuclease ABC subunit C E SPAP_1105 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SPAP_0083 DNA polymerase I - 3'-5' exonuclease and polymerase domains K02335 polA; DNA polymerase I [EC:2.7.7.7] E SPAP_1076 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F SPAP_1971 DNA-directed RNA polymerase, beta subunit/140 kD subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F SPAP_1970 DNA-directed RNA polymerase, beta' subunit/160 kD subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F SPAP_0284 DNA-directed RNA polymerase, alpha subunit/40 kD subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F SPAP_0496 DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta F SPAP_1742 DNA-directed RNA polymerase, subunit K/omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F SPAP_0006 Transcription-repair coupling factor (superfamily II helicase) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors E SPAP_2122 Mismatch repair ATPase (MutS family) K03555 mutS; DNA mismatch repair protein MutS E SPAP_0426 Mismatch repair ATPase (MutS family) K07456 mutS2; DNA mismatch repair protein MutS2 D Molecular matchmaker E SPAP_0227 DNA mismatch repair enzyme (predicted ATPase) K03572 mutL; DNA mismatch repair protein MutL D Strand discrimination factor D DNA exonucleases E SPAP_1233 Exonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E SPAP_1232 Exonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E SPAP_0924 DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E SPAP_0321 DNA polymerase III, alpha subunit K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] E SPAP_0002 DNA polymerase sliding clamp subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E SPAP_0738 DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E SPAP_0967 ATPase involved in DNA replication K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E SPAP_1029 DNA polymerase III, epsilon subunit-like 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E SPAP_0836 DNA polymerase III, gamma/tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E SPAP_1076 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E SPAP_1105 Superfamily I DNA and RNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E SPAP_1562 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E SPAP_1929 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E SPAP_1846 Site-specific DNA methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72] B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E SPAP_0421 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E SPAP_1959 RecA/RadA recombinase K03553 recA; recombination protein RecA E SPAP_0233 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA E SPAP_0307 Holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E SPAP_1741 Primosomal protein N' (replication factor Y) - superfamily II helicase K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D RecFOR pathway proteins E SPAP_1959 RecA/RadA recombinase K03553 recA; recombination protein RecA E SPAP_0075 Predicted ATP-dependent serine protease K04485 radA; DNA repair protein RadA/Sms E SPAP_2270 Recombinational DNA repair ATPase (RecF pathway) K03629 recF; DNA replication and repair protein RecF E SPAP_1704 RecG-like helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E SPAP_0598 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E SPAP_0087 Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O) E SPAP_1677 Recombinational DNA repair protein (RecF pathway) K06187 recR; recombination protein RecR E SPAP_1228 ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N) E SPAP_0394 Penicillin-binding protein-related factor A, putative recombinase K03700 recU; recombination protein U E SPAP_0233 Holliday junction resolvasome, DNA-binding subunit K03550 ruvA; holliday junction DNA helicase RuvA E SPAP_0307 Holliday junction resolvasome, helicase subunit K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D AddAB pathway proteins E SPAP_1061 ATP-dependent exoDNAse (exonuclease V) beta subunit K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] E SPAP_1062 ATP-dependent nuclease, subunit B K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D Other HR factor D Archaeal homologous recombinant proteins C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F SPAP_1245 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F SPAP_0782 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F SPAP_1287 Topoisomerase IA K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F SPAP_1080 Bacterial nucleoid DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F SPAP_0598 Single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] F SPAP_0087 Recombinational DNA repair protein (RecF pathway) K03584 recO; DNA repair protein RecO (recombination protein O) F SPAP_1677 Recombinational DNA repair protein (RecF pathway) K06187 recR; recombination protein RecR F SPAP_1076 NAD-dependent DNA ligase (contains BRCT domain type II) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F SPAP_0239 Excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A F SPAP_1263 Helicase subunit of the DNA excision repair complex K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D SPAP_0472 Nucleotidyltransferase/DNA polymerase involved in DNA repair K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D SPAP_1959 RecA/RadA recombinase K03553 recA; recombination protein RecA D SPAP_1228 ATPase involved in DNA repair K03631 recN; DNA repair protein RecN (Recombination protein N) D SPAP_1562 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPAP_1929 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D SPAP_1920 Uncharacterized protein conserved in bacteria K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D SPAP_0778 Rad3-related DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] C Modulation of nucleotide pools D SPAP_0715 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_0786 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_1046 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_1260 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_1774 NTP pyrophosphohydrolase including oxidative damage repair enzymes K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D SPAP_0073 dUTPase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D SPAP_1209 Ribonucleotide reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D SPAP_1210 Ribonucleotide reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D SPAP_1325 hypothetical protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025