+F Repair protein KO
#
DNA Repair and Recombination Proteins - Sodalis praecaptivus
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Sant_2780 phrB; Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E Sant_1086 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Sant_0735 mutY; Adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Sant_2030 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Sant_3343 mutT; Nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Sant_3988 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Sant_4021 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Sant_0565 Methylated-DNA--protein-cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D Sant_P0278 Ethylated-DNA/protein-cysteine methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D Sant_2780 phrB; Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D Sant_P0331 Deoxyribodipyrimidine photolyase-like protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D Sant_2277 alkB; Alkylated DNA repair protein K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E Sant_1086 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Sant_3628 mug; G:T/U mismatch-specific DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E Sant_1495 alkA; Methylated-DNA--protein-cysteine methyltransferase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Sant_0735 mutY; Adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Sant_1503 tag; 3-methyl-adenine DNA glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Sant_4016 mutM; Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Sant_3818 nei; Endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E Sant_2030 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Sant_1824 xthA; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E Sant_1417 nfo; putative endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E Sant_3912 nfi; Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E Sant_0790 recJ; SsDNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Sant_1246 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Sant_4082 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Sant_3861 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E Sant_2730 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E Sant_2559 uvrC; Excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C
E Sant_0982 Nucleotide excision repair endonuclease K05984 cho; excinuclease Cho [EC:3.1.25.-]
E Sant_0334 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Sant_4082 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Sant_1246 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Sant_3923 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Sant_3922 rpoC; DNA-directed RNA polymerase subunit beta K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Sant_0451 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Sant_4063 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Sant_2461 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Sant_3241 mutS; DNA mismatch repair protein K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E Sant_3512 mutL; DNA mismatch repair protein K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E Sant_0851 mutH; DNA mismatch repair endonuclease K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E Sant_1487 sbcB; Exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E Sant_1151 xseA; Exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Sant_3015 xseB; Exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E Sant_1705 exoX; Exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E Sant_0911 dnaE; DNA polymerase III, subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Sant_0078 dnaN; DNA polymerase III beta-subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Sant_3825 holC; DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E Sant_2821 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Sant_2472 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Sant_3157 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Sant_2975 dnaX; DNA polymerase III subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
E Sant_3434 holD; DNA polymerase III subunit psi K02344 holD; DNA polymerase III subunit psi [EC:2.7.7.7]
E Sant_1706 holE; DNA polymerase III subunit theta K02345 holE; DNA polymerase III subunit theta [EC:2.7.7.7]
D DNA ligase
E Sant_1246 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Sant_0334 uvrD; DNA-dependent helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Sant_3860 ssb; Single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E Sant_0386 dam; DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Sant_0862 recB; Exodeoxyribonuclease V beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E Sant_0860 recC; Exonuclease V gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E Sant_0863 recD; DNA helicase/exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Sant_3227 recA; DNA recombinase A K03553 recA; recombination protein RecA
E Sant_1686 ruvA; Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
E Sant_1687 ruvB; Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Sant_1685 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Sant_3966 priA; Primosome assembly protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Sant_3493 priB; Primosomal replication protein N K02686 priB; primosomal replication protein N
E Sant_2977 priC; Primosomal replication protein N K04067 priC; primosomal replication protein N''
E Sant_1487 sbcB; Exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E Sant_3043 sbcC; SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E Sant_3042 sbcD; Exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Sant_3227 recA; DNA recombinase A K03553 recA; recombination protein RecA
E Sant_3421 radA; DNA repair protein K04485 radA; DNA repair protein RadA/Sms
E Sant_0079 recF; DNA replication and repair protein K03629 recF; DNA replication and repair protein RecF
E Sant_4065 recG; ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Sant_0790 recJ; SsDNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Sant_1100 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
E Sant_2973 recR; Recombination protein K06187 recR; recombination protein RecR
E Sant_1083 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
E Sant_3046 rdgC; Recombination associated protein K03554 rdgC; recombination associated protein RdgC
E Sant_1686 ruvA; Holliday junction DNA helicase motor protein K03550 ruvA; holliday junction DNA helicase RuvA
E Sant_1687 ruvB; Holliday junction DNA helicase B K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Sant_1685 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E Sant_1396 Type III restriction protein res subunit K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E Sant_3043 sbcC; SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E Sant_3042 sbcD; Exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Sant_1369 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Sant_0080 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Sant_1866 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Sant_3910 hupA; Transcriptional regulator HU subunit alpha K05787 hupA; DNA-binding protein HU-alpha
F Sant_2997 hupB; Histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Sant_0790 recJ; SsDNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Sant_1100 recO; DNA repair protein K03584 recO; DNA repair protein RecO (recombination protein O)
F Sant_2973 recR; Recombination protein K06187 recR; recombination protein RecR
F Sant_1246 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F Sant_0490 fis; DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F Sant_2074 ihfA; Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F Sant_2630 ihfB; Integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F Sant_1487 sbcB; Exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F Sant_0340 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Sant_3861 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F Sant_2730 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
F Sant_1832 hns; Global DNA-binding transcriptional dual regulator K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Sant_3148 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Sant_1022 umuC; Putative nucleotidyltransferase/DNA polymerase involved in DNA repair K03502 umuC; DNA polymerase V
D Sant_2864 HumD protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D Sant_2868 SOS mutagenesis and repair protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D Sant_1020 SOS mutagenesis and repair protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D Sant_1021 umuD; SOS mutagenesis and repair protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D Sant_1281 Putative phage DNA polymerase K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D Sant_3227 recA; DNA recombinase A K03553 recA; recombination protein RecA
D Sant_3876 lexA; Transcriptional repressor protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D Sant_1083 recN; DNA repair protein K03631 recN; DNA repair protein RecN (Recombination protein N)
D Sant_3378 polB; DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D Sant_3860 ssb; Single-strand DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D Sant_2488 DNA damage-inducible protein I K12149 dinI; DNA-damage-inducible protein I
D Sant_3226 recX; Regulatory protein K03565 recX; regulatory protein
D Sant_P0230 ISNCY family transposase K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
D Sant_P0258 ISNCY family transposase K24087 rpnB; recombination-promoting nuclease RpnB [EC:3.1.21.-]
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Sant_0284 rep; ATP-dependent DNA helicase K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D Sant_2589 helD; DNA helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D Sant_2694 dinG; ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Sant_1791 yoaA; ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Sant_2245 DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D Sant_3343 mutT; Nucleoside triphosphate pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Sant_3988 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Sant_4021 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Sant_1367 nrdA; Ribonucleoside-diphosphate reductase 1 alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Sant_0949 nrdE; Ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Sant_1366 nrdB; Ribonucleoside-diphosphate reductase 1 beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D Sant_0948 nrdF; Ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024