+E Messenger RNA Biogenesis KO #

  Messenger RNA Biogenesis - Schizosaccharomyces osmophilus (fission yeast)

% ! AEukaryotic type B mRNA processing factors C 5' end processing D Capping factors E SOMG_04123 pcm1; P-TEFb-cap methyltransferase Pcm1 K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] E SOMG_00900 cdc2; cyclin-dependent protein kinase Cdk1/Cdc2 K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22] E SOMG_01001 mcs6; transcription factor TFIIH associated cyclin-dependent protein kinase Mcs6 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] E SOMG_03112 ceg1; mRNA guanylyltransferase Ceg1 K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50] E SOMG_03625 pct1; RNA 5'-triphosphatase K01098 CET1; polynucleotide 5'-triphosphatase [EC:3.6.1.74] D Cap binding complex E SOMG_00812 cbc1; nuclear cap-binding complex large subunit K12882 NCBP1; nuclear cap-binding protein subunit 1 E SOMG_00107 cbc2; nuclear cap-binding complex small subunit K12883 NCBP2; nuclear cap-binding protein subunit 2 C 3' end processing D Pre-mRNA cleavage factor Im (CFIm) D Pre-mRNA cleavage factor IIm (CFIIm) E SOMG_02815 mRNA cleavage and polyadenylation specificity factor complex subunit K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] E SOMG_02760 pcf11; mRNA cleavage and polyadenylation factor complex RNA-binding subunit Pcf11 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 D Cleavage and polyadenylation specificity factor (CPSF) complex E SOMG_01372 cft1; mRNA cleavage and polyadenylation specificity factor complex, WD repeat protein Cft1 K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 E SOMG_01365 cft2; mRNA cleavage and polyadenylation specificity factor complex K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 E SOMG_03282 ysh1; mRNA cleavage and polyadenylation specificity factor complex endoribonuclease subunit Ysh1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] E SOMG_02090 yth1; mRNA cleavage and polyadenylation specificity factor complex zinc finger subunit Yth1 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 E SOMG_01660 iss1; mRNA cleavage and polyadenylation specificity factor complex subunit Iss1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 E SOMG_00643 mpe1; mRNA cleavage ubiquitin-protein ligase E3 Mpe1 K15541 MPE1; protein MPE1 E SOMG_03425 pfs2; mRNA cleavage and polyadenylation specificity factor complex, WD repeat protein Pfs2 K15542 PFS2; polyadenylation factor subunit 2 E SOMG_03134 swd2; Set1C complex subunit Swd2.1 K14962 WDR82; COMPASS component SWD2 E SOMG_01032 dis2; serine/threonine protein phosphatase PP1 catalytic subunit Dis2 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] E SOMG_01980 pzh1; serine/threonine protein phosphatase Pzh1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] E SOMG_04315 sds21; serine/threonine protein phosphatase PP1 catalytic subunit Sds21 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] E SOMG_00330 ssu72; RNA polymerase II CTD phosphatase Ssu72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] D Cleavage stimulation factor (CSTF) complex E SOMG_03532 rna15; RNA-binding protein Rna15 K14407 CSTF2; cleavage stimulation factor subunit 2 E SOMG_01908 rna14; mRNA cleavage and polyadenylation specificity factor complex subunit Rna14 K14408 CSTF3; cleavage stimulation factor subunit 3 E SOMG_04590 pta1; mRNA cleavage and polyadenylation specificity factor complex subunit Pta1 K06100 SYMPK; symplekin D U7-dependent histone pre-mRNA processing factors E SOMG_00764 smb1; Sm snRNP core protein Smb1 K11086 SNRPB; small nuclear ribonucleoprotein B and B' E SOMG_00833 smd3; Sm snRNP core protein Smd3 K11088 SNRPD3; small nuclear ribonucleoprotein D3 E SOMG_03128 sme1; Sm snRNP core protein Sme1 K11097 SNRPE; small nuclear ribonucleoprotein E E SOMG_01174 smf1; Sm snRNP core protein Smf1 K11098 SNRPF; small nuclear ribonucleoprotein F E SOMG_00115 smg1; Sm snRNP core protein Smg1 K11099 SNRPG; small nuclear ribonucleoprotein G E SOMG_01365 cft2; mRNA cleavage and polyadenylation specificity factor complex K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 E SOMG_03282 ysh1; mRNA cleavage and polyadenylation specificity factor complex endoribonuclease subunit Ysh1 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] E SOMG_03532 rna15; RNA-binding protein Rna15 K14407 CSTF2; cleavage stimulation factor subunit 2 E SOMG_04590 pta1; mRNA cleavage and polyadenylation specificity factor complex subunit Pta1 K06100 SYMPK; symplekin D DRB sensitivity inducing factor (DSIF) complex E SOMG_00568 spt4; DSIF transcription elongation factor complex subunit Spt4 K15171 SUPT4H1; transcription elongation factor SPT4 E SOMG_01790 spt5; DSIF transcription elongation factor complex subunit Spt5 K15172 SUPT5H; transcription elongation factor SPT5 D N6-methyltransferase complex E SOMG_03735 mtl16; 23S rRNA/U6 snRNA (adenine-N(6))-methyltransferase Mtl16 K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] D Poly(A) addition factors E SOMG_01452 pla1; mRNA cleavage and polyadenylation specificity factor poly(A) polymerase Pla1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19] D Negative regulators of mRNA 3' end processing C Other processing factors D SOMG_02607 kin17; KIN-like protein K13102 KIN; DNA/RNA-binding protein KIN17 B mRNA surveillance and transport factors C Transport factors D EJC complex E SOMG_04682 rbm8; exon junction complex subunit, RNA-binding protein Rbm8 K12876 RBM8A; RNA-binding protein 8A E SOMG_00488 mnh1; exon junction complex subunit K12877 MAGOH; protein mago nashi E SOMG_03119 mlo3; RNA binding protein Mlo3 K12881 THOC4; THO complex subunit 4 E SOMG_05050 tho4; THO complex subunit Tho4 K12881 THOC4; THO complex subunit 4 E SOMG_03284 uap56; TREX complex subunit, ATP-dependent RNA helicase Uap56 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] E SOMG_03400 fal1; exon junction complex subunit, ATP-dependent RNA helicase, Fal1-like K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] E SOMG_04862 sap18; histone deacetylase complex subunit Sap18 K14324 SAP18; histone deacetylase complex subunit SAP18 E SOMG_03974 pnn1; splicing factor K13114 PNN; pinin E SOMG_00614 rns1; exon junction complex subunit, RNA-binding protein Rns1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1 E SOMG_03029 pwi1; splicing coactivator Srm160 K13171 SRRM1; serine/arginine repetitive matrix protein 1 D TREX complex E SOMG_04541 tho1; THO complex subunit Tho1 K12878 THOC1; THO complex subunit 1 E SOMG_01533 tho2; THO complex subunit Tho2 K12879 THOC2; THO complex subunit 2 E SOMG_04356 tho3; THO complex subunit Tho3 K12880 THOC3; THO complex subunit 3 E SOMG_03119 mlo3; RNA binding protein Mlo3 K12881 THOC4; THO complex subunit 4 E SOMG_05050 tho4; THO complex subunit Tho4 K12881 THOC4; THO complex subunit 4 D TREX-2 complex E SOMG_00687 pci2; TREX/TREX2 complex subunit Pci2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1 E SOMG_02417 rpn15; multifunctional proteasome assembly, lid subcomplex subunit Rpn15/Dss1 K10881 SHFM1; 26 proteasome complex subunit DSS1 E SOMG_01190 sus1; SAGA complex deubiquitinating submodule subunit, TREX complex subunit Sus1 K11368 ENY2; enhancer of yellow 2 transcription factor E SOMG_04213 cdc31; spindle pole body half bridge protein, centrin Cdc31 K16466 CETN3; centrin-3 E SOMG_04102 sac32; nuclear export factor Sac32 K23719 SAC3; nuclear mRNA export protein SAC3 D Nuclear pore complex E SOMG_00337 alm1; nucleoporin Alm1 K09291 TPR; nucleoprotein TPR E SOMG_04794 nup211; nucleoporin nup211 K09291 TPR; nucleoprotein TPR E SOMG_03444 rae1; RNA export factor, nucleoporin Rae1 K14298 RAE1; mRNA export factor E SOMG_00463 sec13; GATOR2-SEACAT complex/COPII-coated vesicle component/nuclear pore outer ring WD repeat protein Sec13 K14004 SEC13; protein transport protein SEC13 E SOMG_02202 nup85; nucleoporin Nup85 K14304 NUP85; nuclear pore complex protein Nup85 E SOMG_00758 nucleoporin Nsp1 K14306 NUP62; nuclear pore complex protein Nup62 E SOMG_04840 nup97; nucleoporin Nic96-like protein K14309 NUP93; nuclear pore complex protein Nup93 E SOMG_00338 nup189; nucleoporin Nup98 and Nup96 K14297 NUP98; nuclear pore complex protein Nup98-Nup96 E SOMG_05032 nup107; nucleoporin Nup107 K14301 NUP107; nuclear pore complex protein Nup107 E SOMG_02361 nup132; nucleoporin, WD repeat Nup132 K14300 NUP133; nuclear pore complex protein Nup133 E SOMG_02020 nup184; nucleoporin Nup184 K14311 NUP188; nuclear pore complex protein Nup188 E SOMG_03476 nup155; nucleoporin, WD repeat Nup155 K14312 NUP155; nuclear pore complex protein Nup155 E SOMG_04908 nup186; nucleoporin Nup186 K14310 NUP205; nuclear pore complex protein Nup205 E SOMG_01659 nup45; nucleoporin Nup45 K14307 NUPL1; nucleoporin p58/p45 E SOMG_01098 amo1; nuclear rim protein Amo1 K14321 NUPL2; nucleoporin-like protein 2 E SOMG_00266 cut11; spindle pole body docking protein Cut11 K14315 NDC1; nucleoporin NDC1 E SOMG_02823 seh1; GATOR2-SEACAT complex WD repeat subunit Seh1 K14299 SEH1; nucleoporin SEH1 E SOMG_00108 nup82; nucleoporin, WD repeat Nup82 K18719 NUP82; nucleoporin NUP82 E SOMG_04353 nup61; nucleoporin Nup61 K18722 NUP2; nucleoporin NUP2 E SOMG_04213 cdc31; spindle pole body half bridge protein, centrin Cdc31 K16466 CETN3; centrin-3 E SOMG_02178 gle1; RNA export factor, cytoplasmic nucleoporin Gle1 K18723 GLE1; nucleoporin GLE1 E SOMG_03219 mex67; mRNA export receptor, Tap, nucleoporin Mex67 K14284 NXF; nuclear RNA export factor E SOMG_03099 nxt1; mRNA export receptor Nxt1 K14285 NXT1_2; NTF2-related export protein 1/2 E SOMG_02594 pom152; nucleoporin, transmembrane ring glycoprotein subunit Pom152 K18725 POM152; nucleoporin POM152 D Ran-mediated transport factors E SOMG_04025 spi1; Ran GTPase Spi1 K07936 RAN; GTP-binding nuclear protein Ran E SOMG_04765 dsc5; UBX domain Sre1 cleavage protein K18726 FAF2; FAS-associated factor 2 E SOMG_01892 cdc48; AAA family ATPase involved in ubiquitin-mediated protein degradation Cdc48 K13525 VCP; transitional endoplasmic reticulum ATPase E SOMG_02347 crm1; karyopherin/importin beta family nuclear export signal receptor Crm1 K14290 XPO1; exportin-1 E SOMG_03464 rna1; Ran GAP GTPase activating protein Rna1 K14319 RANGAP1; Ran GTPase-activating protein 1 D eIF4F and regulatory proteins E SOMG_01363 tif452; translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor K03259 EIF4E; translation initiation factor 4E E SOMG_03316 tif45; translation initiation factor eIF4E, 4F complex subunit K03259 EIF4E; translation initiation factor 4E E SOMG_03935 tif1; translation initiation factor eIF4A tif1 K03257 EIF4A; translation initiation factor 4A E SOMG_03723 tif471; translation initiation factor eIF4G K03260 EIF4G; translation initiation factor 4G E SOMG_03132 sce3; translation initiation factor K03258 EIF4B; translation initiation factor 4B E SOMG_03007 sum3; translation initiation RNA helicase Sum3 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] E SOMG_03603 mpd2; GYF domain protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein E SOMG_01984 pabP; major poly(A) binding protein Pabp/Pab1 K13126 PABPC; polyadenylate-binding protein E SOMG_04537 ski2; Ski complex RNA helicase Ski2 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] E SOMG_00604 slh1; ATP-dependent RNA helicase Slh1, ASCC3-like protein K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6] E SOMG_00589 tma20; RNA-binding protein Tma20 K07575 MCTS; malignant T-cell-amplified sequence E SOMG_03567 tma22; translation machinery associated protein-like protein Tma22 K24272 DENR; density-regulated protein D APOBEC1-ACF complex D Other transport factors E SOMG_02573 mago binding protein K14294 WIBG; partner of Y14 and mago E SOMG_02166 msi2; mRNA cleavage factor complex subunit Msi2 K14411 MSI; RNA-binding protein Musashi E SOMG_04352 dom34; Dom34-Hbs1 translation release factor complex subunit K06965 PELO; protein pelota E SOMG_01526 pab2; poly(A) binding protein Pab2 K14396 PABPN1; polyadenylate-binding protein 2 E SOMG_02631 dbp5; cytoplasmic ATP-dependent RNA helicase Dbp5 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] E SOMG_00552 cwf3; Prp19 complex subunit Cwf3 K12867 SYF1; pre-mRNA-splicing factor SYF1 E SOMG_04313 mlo1; RNA binding protein K18732 SARNP; SAP domain-containing ribonucleoprotein E SOMG_02621 pim1; RCC1 family Ran GEF K11493 RCC1; regulator of chromosome condensation E SOMG_01129 iss9; SAC3/GANP/THP3 family protein, LENG8-like protein K23802 LENG8; SAC3 family protein LENG8/THP3 E SOMG_03336 hrb1; RNA-binding protein involved in export of mRNAs Hrb1 K28506 GBP2; serine/arginine (SR)-type shuttling mRNA binding protein C Surveillance factors D Surveillance complex E SOMG_03883 erf1; cytoplasmic translation release factor class I eRF1 K03265 ETF1; peptide chain release factor subunit 1 E SOMG_04806 sup35; cytoplasmic translation release factor class II, GTPase eRF3 K03267 ERF3; peptide chain release factor subunit 3 E SOMG_01680 upf1; ATP-dependent RNA helicase Upf1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] E SOMG_02857 upf2; nonsense-mediated decay protein Upf2 K14327 UPF2; regulator of nonsense transcripts 2 E SOMG_02778 upf3; up-frameshift suppressor 3 family protein K14328 UPF3; regulator of nonsense transcripts 3 D Protein phosphatase 2A E SOMG_01494 ppa2; serine/threonine protein phosphatase PP2A catalytic subunit Ppa2 K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] E SOMG_03655 ppa1; serine/threonine protein phosphatase PP2A catalytic subunit Ppa1 K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] E SOMG_02395 paa1; serine/threonine protein phosphatase PP2A scaffold subunit Paa1 K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A E SOMG_02089 pab1; serine/threonine protein phosphatase PP2A regulatory subunit B-55 Pab1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B E SOMG_01903 par2; serine/threonine protein phosphatase PP2A regulatory subunit B-56 Par2 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' E SOMG_04821 par1; serine/threonine protein phosphatase PP2A regulatory subunit B-56 Par1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' D Other surveillance factors E SOMG_03603 mpd2; GYF domain protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein C Factors involved in mRNA localization D Cargo complex E SOMG_04985 puf6; pumilio family RNA-binding protein Puf6 K14844 PUF6; pumilio homology domain family member 6 E SOMG_02529 rnc1; KH domain RNA-binding protein Rnc1 K18738 HEK; heterogeneous nuclear rnp K-like protein E SOMG_01115 myo51; myosin type V K10357 MYO5; myosin V E SOMG_04971 myo52; myosin type V K10357 MYO5; myosin V D Factors that have mRNA localization signals D Trans-acting binding proteins E SOMG_01332 KH domain RNA-binding protein K13210 FUBP; far upstream element-binding protein E SOMG_02306 tef103; translation elongation factor EF-1 alpha Ef1a-c K03231 EEF1A; elongation factor 1-alpha E SOMG_04173 tef101; translation elongation factor EF-1 alpha Ef1a-a K03231 EEF1A; elongation factor 1-alpha E SOMG_04683 tef102; translation elongation factor EF-1 alpha Ef1a-b K03231 EEF1A; elongation factor 1-alpha E SOMG_03962 translation elongation factor EF-1 gamma subunit K03233 EEF1G; elongation factor 1-gamma E SOMG_04301 glutathione S-transferase, translational elongation factor eEF1 K03233 EEF1G; elongation factor 1-gamma D Other mRNA localization factors E SOMG_01038 cytoplasmic P body 3'-5'-exoribonuclease, Dis3L2-related K18748 SSD1; protein SSD1 E SOMG_04335 sts5; cytoplasmic P body 3'-5'-exoribonuclease, Dis3L2-related K18748 SSD1; protein SSD1 C mRNA cycle factors D Common to processing body (P body) and stress granule E SOMG_00363 exo2; exonuclease II Exo2 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] E SOMG_04199 ago1; argonaute K11593 ELF2C; eukaryotic translation initiation factor 2C E SOMG_01363 tif452; translation initiation factor eIF4E, 4F complex E subunit isoform 2, stress response factor K03259 EIF4E; translation initiation factor 4E E SOMG_03316 tif45; translation initiation factor eIF4E, 4F complex subunit K03259 EIF4E; translation initiation factor 4E E SOMG_01680 upf1; ATP-dependent RNA helicase Upf1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3] E SOMG_03007 sum3; translation initiation RNA helicase Sum3 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] E SOMG_01025 ste13; ATP-dependent RNA helicase Ste13/Dhh1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] E SOMG_02188 sum2; translation initiation inhibitor K18749 LSM14; protein LSM14 E SOMG_04625 kap104; karyopherin/importin beta family nuclear import signal receptor Kap104 K18752 TNPO1; transportin-1 E SOMG_05052 pka1; cAMP-dependent protein kinase catalytic subunit Pka1 K04345 PKA; protein kinase A [EC:2.7.11.11] D P-body specific factors E SOMG_02853 dcp2; mRNA decapping complex catalytic subunit Dcp2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] E SOMG_01293 lsm1; mRNA decapping complex subunit K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 E SOMG_04865 lsm2; Lsm2-8 complex subunit Lsm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 E SOMG_03150 lsm3; Lsm2-8 complex subunit Lsm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 E SOMG_01069 lsm4; Lsm2-8 complex subunit Lsm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 E SOMG_00974 lsm5; Lsm2-8 complex subunit Lsm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 E SOMG_04620 lsm6; Lsm2-8 complex subunit Lsm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 E SOMG_04764 lsm7; Lsm2-8 complex Lsm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 E SOMG_04945 lsm8; Lsm2-8 complex Lsm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 E SOMG_01115 myo51; myosin type V K10357 MYO5; myosin V E SOMG_04971 myo52; myosin type V K10357 MYO5; myosin V E SOMG_02184 atb2; tubulin alpha 2 K07374 TUBA; tubulin alpha E SOMG_03452 nda2; tubulin alpha 1 K07374 TUBA; tubulin alpha E SOMG_01929 not1; CCR4-Not complex scaffold subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1 E SOMG_04237 not2; CCR4-Not complex NOT box subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2 E SOMG_03512 not3; CCR4-Not complex NOT box subunit 3/5 K12580 CNOT3; CCR4-NOT transcription complex subunit 3 E SOMG_01678 mot2; CCR4-Not complex ubiquitin-protein ligase E3 subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] E SOMG_04319 ccr4; CCR4-Not complex 3'-5'-exoribonuclease subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] E SOMG_04895 caf1; CCR4-Not complex CAF1 family ribonuclease subunit 7/8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 E SOMG_02942 dis32; 3'-5'-exoribonuclease activity Dis3L2 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] E SOMG_01654 pan2; PAN complex (poly(A)-specific ribonuclease) ubiquitin C-terminal hydrolase subunit Pan2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] E SOMG_00703 ppk26; PAN complex protein phosphotransferase subunit Ppk26 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 E SOMG_03199 pdc2; topoisomerase II-associated deadenylation-dependent mRNA-decapping factor Pdc2 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 E SOMG_02126 edc3; enhancer of mRNA decapping Edc3 K12615 EDC3; enhancer of mRNA-decapping protein 3 E SOMG_02857 upf2; nonsense-mediated decay protein Upf2 K14327 UPF2; regulator of nonsense transcripts 2 E SOMG_02778 upf3; up-frameshift suppressor 3 family protein K14328 UPF3; regulator of nonsense transcripts 3 E SOMG_00218 rpb7; DNA-directed RNA polymerase complex II subunit Rpb7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 D Stress granule specific factors E SOMG_01984 pabP; major poly(A) binding protein Pabp/Pab1 K13126 PABPC; polyadenylate-binding protein E SOMG_00647 nxt3; ubiquitin protease cofactor Nxt3 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 E SOMG_00114 eif21; translation initiation factor eIF2A K15026 EIF2A; translation initiation factor 2A E SOMG_02924 tif302; translation initiation factor eIF3b (p84) K03253 EIF3B; translation initiation factor 3 subunit B E SOMG_03935 tif1; translation initiation factor eIF4A tif1 K03257 EIF4A; translation initiation factor 4A E SOMG_03400 fal1; exon junction complex subunit, ATP-dependent RNA helicase, Fal1-like K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] E SOMG_03132 sce3; translation initiation factor K03258 EIF4B; translation initiation factor 4B E SOMG_03723 tif471; translation initiation factor eIF4G K03260 EIF4G; translation initiation factor 4G E SOMG_02843 cpc2; ribosome-associated signaling scaffold K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein E SOMG_03219 mex67; mRNA export receptor, Tap, nucleoporin Mex67 K14284 NXF; nuclear RNA export factor E SOMG_02175 clr3; histone deacetylase (class II) Clr3 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] B mRNA degradation factors C 5'-3' decay D Decapping complex E SOMG_02853 dcp2; mRNA decapping complex catalytic subunit Dcp2 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] E SOMG_01025 ste13; ATP-dependent RNA helicase Ste13/Dhh1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] E SOMG_02126 edc3; enhancer of mRNA decapping Edc3 K12615 EDC3; enhancer of mRNA-decapping protein 3 E SOMG_03199 pdc2; topoisomerase II-associated deadenylation-dependent mRNA-decapping factor Pdc2 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1 D Lsm complex E SOMG_01293 lsm1; mRNA decapping complex subunit K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 E SOMG_04865 lsm2; Lsm2-8 complex subunit Lsm2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 E SOMG_03150 lsm3; Lsm2-8 complex subunit Lsm3 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 E SOMG_01069 lsm4; Lsm2-8 complex subunit Lsm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 E SOMG_00974 lsm5; Lsm2-8 complex subunit Lsm5 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 E SOMG_04620 lsm6; Lsm2-8 complex subunit Lsm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 E SOMG_04764 lsm7; Lsm2-8 complex Lsm7 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 E SOMG_04945 lsm8; Lsm2-8 complex Lsm8 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 D 5' exonucleases E SOMG_00363 exo2; exonuclease II Exo2 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] E SOMG_00760 dhp1; 5'-3' exoribonuclease Dhp1 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-] D Other 5'-3' decay factors E SOMG_00721 nhm1; m7G(5')PppN diphosphatase Nhm1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] C 3'-5' decay D Core exosome factors E SOMG_04946 csl4; exosome subunit Csl4 K07573 CSL4; exosome complex component CSL4 E SOMG_01586 rrp4; exosome subunit Rrp4 K03679 RRP4; exosome complex component RRP4 E SOMG_01836 rrp40; exosome subunit Rrp40 K03681 RRP40; exosome complex component RRP40 E SOMG_00323 rrp41; exosome subunit Rrp41 K11600 RRP41; exosome complex component RRP41 E SOMG_02302 rrp46; exosome subunit Rrp46 K12590 RRP46; exosome complex component RRP46 E SOMG_00546 mtr3; exosome subunit Mtr3 K12587 MTR3; exosome complex component MTR3 E SOMG_03912 rrp42; exosome subunit Rrp42 K12589 RRP42; exosome complex component RRP42 E SOMG_00962 rrp43; exosome subunit Rrp43 K12586 RRP43; exosome complex component RRP43 E SOMG_02528 rrp45; exosome subunit Rrp45 K03678 RRP45; exosome complex component RRP45 D Exosome cofactors E SOMG_00502 dis3; exosome 3'-5' exoribonuclease subunit Dis3 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] E SOMG_01567 rrp6; exosome 3'-5' exoribonuclease subunit Rrp6 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] E SOMG_04929 cti1; exosome C1D family subunit Cti1 K12592 C1D; exosome complex protein LRP1 E SOMG_00213 mpp6; nuclear exosome-associated RNA binding protein Mpp6 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type E SOMG_04723 DEAD/DEAH box helicase, DDL60 and DDL60L-like protein, implicated in mRNA degradation K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7] D TRAMP complex E SOMG_03426 cid14; TRAMP complex poly(A) polymerase subunit Cid14 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] E SOMG_01430 air1; TRAMP complex zinc knuckle subunit Air1 K12597 AIR1_2; protein AIR1/2 E SOMG_01907 mtr4; TRAMP complex ATP-dependent RNA helicase subunit Mtr4 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] E SOMG_02646 mtl1; MTREC (exosome adaptor) complex RNA helicase subunit Mtl1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] D Ski complex E SOMG_04537 ski2; Ski complex RNA helicase Ski2 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] E SOMG_04941 ski3; Ski complex TPR repeat subunit Ski3 K12600 SKI3; superkiller protein 3 E SOMG_04994 rec14; Ski complex subunit Rec14 K12601 SKI8; superkiller protein 8 D Ccr4-NOT complex E SOMG_04319 ccr4; CCR4-Not complex 3'-5'-exoribonuclease subunit 6 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] E SOMG_01929 not1; CCR4-Not complex scaffold subunit 1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1 E SOMG_04237 not2; CCR4-Not complex NOT box subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2 E SOMG_03512 not3; CCR4-Not complex NOT box subunit 3/5 K12580 CNOT3; CCR4-NOT transcription complex subunit 3 E SOMG_01678 mot2; CCR4-Not complex ubiquitin-protein ligase E3 subunit 4 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] E SOMG_04895 caf1; CCR4-Not complex CAF1 family ribonuclease subunit 7/8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 E SOMG_02432 rcd1; CCR4-Not complex RNA-binding protein subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9 E SOMG_03823 caf16; CCR4-Not complex ATPase subunit Caf16 K12608 CAF16; CCR4-NOT complex subunit CAF16 D Pan complex E SOMG_01654 pan2; PAN complex (poly(A)-specific ribonuclease) ubiquitin C-terminal hydrolase subunit Pan2 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] E SOMG_00703 ppk26; PAN complex protein phosphotransferase subunit Ppk26 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 D Other 3'-5' decay factors E SOMG_01279 eri1; double-strand siRNA ribonuclease Eri1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-] E SOMG_00721 nhm1; m7G(5')PppN diphosphatase Nhm1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] E SOMG_00978 nrl1; RNAi-mediated silencing protein, NRDE2-like protein Nrl1-like K26109 NRDE2; nuclear exosome regulator NRDE2 E SOMG_01090 vts1; Smaug family RNA-binding protein Vts1 K27407 VTS1; RNA-binding protein VTS1 C Other degradation factors D RNases # AProkaryotic type B Bacterial mRNA degradation factors C RNA degradosome components D Ribonucreases E SOMG_02278 pac1; double-strand-specific ribonuclease Pac1 K03685 rnc; ribonuclease III [EC:3.1.26.3] E SOMG_00456 rex2; RNA exonuclease K13288 orn; oligoribonuclease [EC:3.1.-.-] D Helicases D Other RNA degradosome components E SOMG_00049 eno102; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] E SOMG_02214 eno101; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] E SOMG_01500 pfk1; 6-phosphofructokinase pfk1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] C Other RNA degradation factors D Chaperones E SOMG_00389 ssc1; mitochondrial (2Fe-2S) cluster assembly chaperone Ssc1 K04043 dnaK; molecular chaperone DnaK E SOMG_03588 mcp60; mitochondrial heat shock protein Hsp60/Mcp60 K04077 groEL; chaperonin GroEL [EC:5.6.1.7] D Others D Bacterial Small RNA Regulators B Archeal mRNA degradation factors C Exosome components D Core exosome E SOMG_01586 rrp4; exosome subunit Rrp4 K03679 RRP4; exosome complex component RRP4 E SOMG_04946 csl4; exosome subunit Csl4 K07573 CSL4; exosome complex component CSL4 D Cofactors E SOMG_00323 rrp41; exosome subunit Rrp41 K11600 RRP41; exosome complex component RRP41 E SOMG_03912 rrp42; exosome subunit Rrp42 K12589 RRP42; exosome complex component RRP42 D Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 27, 2025