+D	Protein	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Membrane Trafficking - Schizosaccharomyces osmophilus (fission yeast)</h2>
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A<b>Exocytosis</b>
B  Calcium ion-dependent exocytosis
C    Synaptotagmins
D      SOMG_00219 tcb3; tricalbin, C2 domain protein (phospholipid binding) ER-plasma membrane tethering protein Tcb3	K28063 ESYT; extended synaptotagmin 
D      SOMG_04278 tcb2; tricalbin, C2 domain protein (phospholipid binding) ER-plasma membrane tethering protein Tcb2	K28063 ESYT; extended synaptotagmin 
D      SOMG_04281 tcb1; tricalbin, C2 domain protein (phospholipid binding) ER-plasma membrane tethering protein Tcb1	K28063 ESYT; extended synaptotagmin 
C    Septins
D      SOMG_03601 spn1; mitotic septin Spn1	K16944 SEPT7; septin 7 
C    DOC-2 proteins
C    Acrosomal exocytosis proteins
D      SOMG_04866 ksg1; serine/threonine protein kinase Ksg1	K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] 
C    Phospholipases
D      SOMG_03825 plc1; phosphoinositide phospholipase C Plc1	K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] 
D      SOMG_01584 pld1; phospholipase D, Pld1	K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4] 
C    Kinases and associated proteins
D      SOMG_04672 its3; 1-phosphatidylinositol-4-phosphate 5-kinase Its3	K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] 
D      SOMG_00537 shk1; PAK-related kinase Shk1	K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1] 
D      SOMG_02639 sid1; PAK-related GC kinase Sid1	K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] 
D      SOMG_02935 ppk11; PAK-related GC kinase Ppk11	K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] 
D      SOMG_03406 ndk1; nucleoside diphosphate kinase Ndk1	K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6] 
D      SOMG_01169 kin1; microtubule affinity-regulating kinase Kin1	K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1] 
C    Others
D      SOMG_03421 ncs1; neuronal calcium sensor related protein Ncs1	K19932 NCS1; neuronal calcium sensor 
B  Small GTPases and associated proteins
C    Rab GTPases
D      SOMG_02875 ypt2; GTPase Ypt2	K07901 RAB8A; Ras-related protein Rab-8A 
C    Rab associated proteins
D      SOMG_01949 cam1; calmodulin Cam1	K02183 CALM; calmodulin 
D      SOMG_03959 cam2; myosin I light chain Cam2	K02183 CALM; calmodulin 
D      SOMG_01781 sec2; Rab GEF Sec2	K19940 SEC2; Rab guanine nucleotide exchange factor SEC2 
D      SOMG_04805 sec1; SNARE binding protein Sec1	K15292 STXBP1; syntaxin-binding protein 1 
D      SOMG_01565 sro7; Lgl family protein Sro7	K08518 STXBP5; syntaxin-binding protein 5 
D      SOMG_01047 dss4; guanyl-nucleotide exchange factor, meiosis specific	K19952 RABIF; guanine nucleotide exchange factor 
D      SOMG_04246 gyp3; Rab GAP Gyp3	K19953 GRTP1; TBC1 domain family member 6 
D      SOMG_00475 Rab GAP	K19951 TBC1D8_9; TBC1 domain family member 8/9 
D      SOMG_01325 pex5; peroxisomal targeting signal receptor Pex5	K13342 PEX5; peroxin-5 
D      SOMG_02234 mrs6; Rab geranylgeranyltransferase escort protein Mrs6	K23460 CHM; Rab proteins geranylgeranyltransferase component A 
D      SOMG_04846 bet4; Rab geranylgeranyltransferase alpha subunit Bet4	K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60] 
D      SOMG_01990 ptb1; geranylgeranyltransferase II beta subunit Ptb1	K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] 
D      SOMG_00690 rav1; RAVE complex subunit Rav1	K24155 DMXL; rabconnectin-3a 
C    Rho GTPases
D      SOMG_03260 cdc42; Rho family GTPase Cdc42	K04393 CDC42; cell division control protein 42 
C    Other small GTPases and associated proteins
B  Tethering complex
C    Exocyst complex
D      SOMG_04150 sec6; exocyst complex subunit Sec6	K06110 EXOC3; exocyst complex component 3 
D      SOMG_04262 sec8; exocyst complex subunit Sec8	K06111 EXOC4; exocyst complex component 4 
D      SOMG_02728 sec10; exocyst complex subunit Sec10	K19984 EXOC5; exocyst complex component 5 
D      SOMG_04300 sec15; exocyst complex subunit Sec15	K19985 EXOC6; exocyst complex component 6 
D      SOMG_05041 exo70; exocyst complex subunit Exo70	K07195 EXOC7; exocyst complex component 7 
C    Exocyst complex assembly proteins
D      SOMG_02417 rpn15; multifunctional proteasome assembly, lid subcomplex subunit Rpn15/Dss1	K10881 SHFM1; 26 proteasome complex subunit DSS1 
D      SOMG_02922 tropomyosin	K17945 TPM1_2; tropomyosin, fungi type 
B  Others
C    Exomer complex
D      SOMG_00796 chs five like protein Cfr1	K19877 CHS5; chitin biosynthesis protein CHS5 
D      SOMG_00585 bch1; exomer complex ChAPs family (Chs5p-Arf1p-binding) protein Bch1	K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1 
C    Others
D      SOMG_03291 pep7; prevacuole/endosomal FYVE tethering component Pep7	K12481 RBSN; rabenosyn-5 
#
A<b>SNARE</b>
B  Syntaxin (Qa)
C    Stx-PM
D      SOMG_03027 psy1; plasma membrane SNARE Psy1	K08486 STX1B_2_3; syntaxin 1B/2/3 
C    Stx-Endo
C    Stx-TGN / EE
D      SOMG_03667 tlg2; SNARE Tlg2	K08489 STX16; syntaxin 16 
C    Stx-cisGolgi
D      SOMG_01252 sed5; SNARE Sed5	K08490 STX5; syntaxin 5 
C    Stx-sER
C    Stx-rER
D      SOMG_03019 ufe1; SNARE Ufe1	K08492 STX18; syntaxin 18 
B  SNAP-25[N] (Qb)
C    Vti1
D      SOMG_00486 vti1; SNARE Vti1	K08493 VTI1; vesicle transport through interaction with t-SNAREs 1 
C    NPSN
C    Gos1 (Gos28)
D      SOMG_01671 gos1; SNARE Gos1	K08495 GOSR1; golgi SNAP receptor complex member 1 
C    Bos1 / Membrin
D      SOMG_03257 bos1; SNARE Bos1	K08496 GOSR2; golgi SNAP receptor complex member 2 
C    Sec20
D      SOMG_04687 sec20; SNARE Sec20	K08497 SEC20; protein transport protein SEC20 
B  SNAP-25[C] (Qc)
C    STX6
D      SOMG_03212 tlg1; SNARE Tlg1	K08499 TLG1; member of the syntaxin family of t-SNAREs 
C    STX8
D      SOMG_01894 fsv1; SNARE Stx8	K08501 STX8; syntaxin 8 
D      SOMG_04208 vsl1; vacuolar SNARE Vsl1/Vam7	K08502 VAM7; regulator of vacuolar morphogenesis 
C    STX10
C    Bet1
D      SOMG_01784 bet1; SNARE Bet1	K08504 BET1; blocked early in transport 1 
C    Sft1
D      SOMG_02053 sft1; SNARE Sft1	K08505 SFT1; protein transport protein SFT1 
C    Syp7
C    Use1
B  SNAP-25 (Qb,c)
C    SNAP-23
C    SNAP-25
D      SOMG_00516 sec9; SNAP-25-like proteinue	K19950 SEC9; protein transport protein SEC9 
C    SNAP-29
C    SNAP-47
B  VAMP, Ykt6, Sec22 (R)
C    VAMP
D      SOMG_00797 syb1; SNAP receptor, synaptobrevin family	K08513 VAMP4; vesicle-associated membrane protein 4 
C    Ykt6
D      SOMG_00603 ykt6; SNARE Ykt6	K08516 YKT6; synaptobrevin homolog YKT6 
C    Sec22
D      SOMG_01132 sec22; SNARE Sec22	K08517 SEC22; vesicle transport protein SEC22 
C    Tomosyn
D      SOMG_01565 sro7; Lgl family protein Sro7	K08518 STXBP5; syntaxin-binding protein 5 
C    Putative SNAREs
B  SNARE associated proteins
C    Syntaxin-binding proteins
D      SOMG_04805 sec1; SNARE binding protein Sec1	K15292 STXBP1; syntaxin-binding protein 1 
D      SOMG_04940 sly1; SNARE binding protein Sly1	K19998 SCFD1; sec1 family domain-containing protein 1 
C    Palmitoyltransferases
D      SOMG_00607 swf1; palmitoyltransferase Swf1	K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225] 
D      SOMG_01589 akr1; palmitoyltransferase Akr1	K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225] 
C    Others
D      SOMG_03891 sec18; secretory pathway ATPase Sec18	K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6] 
D      SOMG_00748 sec17; alpha SNAP	K15296 NAPA; alpha-soluble NSF attachment protein 
D      SOMG_02370 atg24; autophagy associated PX/BAR domain sorting nexin Atg24	K17919 SNX4; sorting nexin-4 
D      SOMG_03803 snx41; PX domain sorting nexin Snx41	K21996 SNX41_42; sorting nexin-41/42 
D      SOMG_01965 gpp74; Golgi phosphoprotein 3 family Vps74	K15620 GOLPH3; golgi phosphoprotein 3 
D      SOMG_01892 cdc48; AAA family ATPase involved in ubiquitin-mediated protein degradation Cdc48	K13525 VCP; transitional endoplasmic reticulum ATPase 
D      SOMG_02032 ubx3; UBX domain protein Ubx3, Cdc48 cofactor	K14012 NSFL1C; UBX domain-containing protein 1 
D      SOMG_01090 vts1; Smaug family RNA-binding protein Vts1	K27407 VTS1; RNA-binding protein VTS1 
#
A<b>Endocytosis</b>
B  Clathrin-mediated endocytosis
C    Clathrin
D      SOMG_00767 chc1; clathrin heavy chain Chc1	K04646 CLTC; clathrin heavy chain 
C    Dynamin
D      SOMG_03238 dnm1; mitochondrial dynamin family scission GTPase Dnm1	K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5] 
C    AP-2 complex
D      SOMG_00933 apl3; AP-2 adaptor complex alpha subunit Alp3	K11824 AP2A; AP-2 complex subunit alpha 
D      SOMG_00401 apm4; AP-2 adaptor complex mu subunit Apm4	K11826 AP2M1; AP-2 complex subunit mu-1 
D      SOMG_05002 aps2; AP-2 adaptor complex sigma subunit Aps2	K11827 AP2S1; AP-2 complex subunit sigma-1 
C    Other core components
D      SOMG_01050 syp1; F-BAR domain protein Syp1	K20042 FCHO; F-BAR domain only protein 
D      SOMG_04176 ent3; ENTH/VHS domain protein Ent3	K12471 EPN; epsin 
D      SOMG_04793 ent1; epsin	K12471 EPN; epsin 
D      SOMG_02460 ede1; EPS15 repeat family actin cortical patch component Ede1	K12472 EPS15; epidermal growth factor receptor substrate 15 
D      SOMG_01005 yap18; ENTH/VHS domain protein	K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein 
D      SOMG_03224 hob1; BAR adaptor protein Hob1	K12562 AMPH; amphiphysin 
D      SOMG_03329 shd1; cytoskeletal protein binding protein Sla1 family, Shd1	K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1 
D      SOMG_02923 pan1; actin cortical patch component, with EF hand and WH2 motif Panl	K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1 
D      SOMG_03124 end3; actin cortical patch component End3	K20048 END3; actin cytoskeleton-regulatory complex protein END3 
D      SOMG_01376 sks2; heat shock protein, Hsp70 family, ribosome associated Sks2	K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
D      SOMG_02777 ssa1; Hsp70 family heat shock protein Ssa1	K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
D      SOMG_04935 ssa2; Hsp70 family heat shock protein Ssa2	K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
C    Low-density lipoprotein receptor (LDLR) family proteins
C    LDLR adaptor proteins
D      SOMG_04672 its3; 1-phosphatidylinositol-4-phosphate 5-kinase Its3	K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] 
C    GPCR adaptor proteins
D      SOMG_03147 any1; arrestin-related substrate adaptor Any1	K20059 LDB19; arrestin-related trafficking adapter 1 
D      SOMG_04572 any2; arrestin-related substrate adaptor Any2	K20059 LDB19; arrestin-related trafficking adapter 1 
D      SOMG_01126 aly2; arrestin-related endocytic ubiquitin ligase substrate adaptor Aly2	K20061 ALY1_2; arrestin-related trafficking adapter 3/6 
D      SOMG_02320 aly1; arrestin-related substrate adaptor Aly1	K20061 ALY1_2; arrestin-related trafficking adapter 3/6 
D      SOMG_02052 rod1; arrestin-related substrate adaptor Rod1	K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7 
D      SOMG_04810 aly3; arrestin-related substrate adaptor Aly3	K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7 
C    Receptor tyrosine kinase (RTK) adaptor proteins
C    Inositol 5-phosphatases
D      SOMG_00124 syj1; inositol-polyphosphate 5-phosphatase	K20279 SYNJ; synaptojanin [EC:3.1.3.36] 
D      SOMG_02256 syj2; inositol-polyphosphate 5-phosphatase	K20279 SYNJ; synaptojanin [EC:3.1.3.36] 
C    Kinases
D      SOMG_01197 ppk30; Ark1/Prk1 family protein kinase Ppk30	K08853 AAK; AP2-associated kinase [EC:2.7.11.1] 
D      SOMG_04118 ppk38; Ark1/Prk1 family protein kinase Ppk38	K08853 AAK; AP2-associated kinase [EC:2.7.11.1] 
D      SOMG_01611 ppk32; serine/threonine protein kinase Ppk32	K17541 SCYL2; SCY1-like protein 2 
C    Ubiquitin E3 ligases
D      SOMG_01527 pub3; HECT-type ubiquitin-protein ligase E3 Pub3	K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] 
D      SOMG_02349 pub2; HECT-type ubiquitin-protein ligase E3 Pub2	K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] 
D      SOMG_04637 pub1; HECT-type ubiquitin-protein ligase E3 Pub1	K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26] 
C    Others
D      SOMG_00312 end4; Clathrin adaptor End4	K20040 HIP1R; huntingtin-interacting protein 1-related protein 
D      SOMG_02694 cnx1; calnexin Cnx1	K08054 CANX; calnexin 
B  Lipid raft mediated endocytosis
C    Caveolin-mediated endocytosis
D      SOMG_03238 dnm1; mitochondrial dynamin family scission GTPase Dnm1	K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5] 
D      SOMG_02811 pck1; protein kinase C (PKC)-like Pck1	K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13] 
C    Flotillin-dependent endocytosis
C    GRAF1-dependent endocytosis
D      SOMG_03260 cdc42; Rho family GTPase Cdc42	K04393 CDC42; cell division control protein 42 
D      SOMG_01153 arf1; ADP-ribosylation factor, Arf family Arf1	K07937 ARF1_2; ADP-ribosylation factor 1/2 
C    Arf6-dependent endocytosis
D      SOMG_03546 arf6; ADP-ribosylation factor, Arf family Arf6	K07941 ARF6; ADP-ribosylation factor 6 
C    RhoA-dependent endocytosis
D      SOMG_02705 rho5; Rho family GTPase Rho5	K04513 RHOA; Ras homolog gene family, member A 
D      SOMG_04732 rho1; Rho family GTPase Rho1	K04513 RHOA; Ras homolog gene family, member A 
D      SOMG_03238 dnm1; mitochondrial dynamin family scission GTPase Dnm1	K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5] 
B  Phagocytosis
C    Fc receptors
C    Integrins (complement receptors)
C    Opsonins
C    Toll-like receptors
C    C-lectin receptors
C    Scavenger receptors
C    Coronins
C    Others
D      SOMG_01411 myo1; myosin type I	K10356 MYO1; myosin I 
B  Macropinocytosis
C    Ras GTPases
D      SOMG_02653 ras1; GTPase Ras1	K07827 KRAS; GTPase KRas 
D      SOMG_03260 cdc42; Rho family GTPase Cdc42	K04393 CDC42; cell division control protein 42 
C    Kinases
D      SOMG_03860 pik3; phosphatidylinositol 3-kinase Pik3	K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137] 
D      SOMG_01185 fab1; 1-phosphatidylinositol-3-phosphate 5-kinase Fab1	K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150] 
D      SOMG_00537 shk1; PAK-related kinase Shk1	K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1] 
C    Phospholipase C
D      SOMG_03825 plc1; phosphoinositide phospholipase C Plc1	K05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] 
C    Sorting nexins
D      SOMG_04346 vps5; retromer complex subunit Vps5	K17917 SNX1_2; sorting nexin-1/2 
C    Others
B  Bin/Amphiphysin/Rvs (BAR) family proteins
C    N-BAR proteins
D      SOMG_03224 hob1; BAR adaptor protein Hob1	K12562 AMPH; amphiphysin 
D      SOMG_01323 hob3; BAR adaptor protein Hob3	K20120 BIN3; bridging integrator 3 
C    F-BAR proteins
D      SOMG_02630 bzz1; F-BAR domain protein Bzz1	K20121 FNBP1; formin-binding protein 1 
D      SOMG_01050 syp1; F-BAR domain protein Syp1	K20042 FCHO; F-BAR domain only protein 
D      SOMG_02134 rga7; RhoGAP Rga7	K20643 RGD1; Rho GTPase-activating protein RGD1 
C    I-BAR proteins
B  Rab GTPases and associated proteins
C    Rab GTPases
D      SOMG_02367 ypt5; GTPase Ypt5	K07888 RAB5B; Ras-related protein Rab-5B 
C    Rab associated proteins
D      SOMG_01165 vps901; GEF Vps901	K20131 RABGEF1; Rab5 GDP/GTP exchange factor 
D      SOMG_03291 pep7; prevacuole/endosomal FYVE tethering component Pep7	K12481 RBSN; rabenosyn-5 
D      SOMG_03860 pik3; phosphatidylinositol 3-kinase Pik3	K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137] 
D      SOMG_02282 vps15; serine/threonine protein kinase Vps15	K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] 
D      SOMG_01683 vps45; vacuolar sorting protein Vps45	K12479 VPS45; vacuolar protein sorting-associated protein 45 
B  Arf GTPases and associated proteins
C    Arf GTPases
D      SOMG_01153 arf1; ADP-ribosylation factor, Arf family Arf1	K07937 ARF1_2; ADP-ribosylation factor 1/2 
D      SOMG_03546 arf6; ADP-ribosylation factor, Arf family Arf6	K07941 ARF6; ADP-ribosylation factor 6 
C    Arf associated proteins
D      SOMG_00400 GTPase activating protein	K12486 SMAP; stromal membrane-associated protein 
B  Others
C    Fucosyltransferase
C    EFR3-PI4KIII alpha complex and associated proteins
D      SOMG_02266 stt4; 1-phosphatidylinositol 4-kinase Stt4	K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67] 
D      SOMG_04172 efr3; phosphatidylinositol-4 kinase plasma membrane scaffold Efr3	K21842 EFR3; protein EFR3 
C    Insulin-like growth factor-binding proteins
C    Others
#
A<b>Endosome - Lysosome transport</b>
B  Rab GTPases and associated proteins
C    Rab GTPases
D      SOMG_02367 ypt5; GTPase Ypt5	K07888 RAB5B; Ras-related protein Rab-5B 
D      SOMG_01042 ypt7; GTPase Ypt7	K07897 RAB7A; Ras-related protein Rab-7A 
D      SOMG_03273 ypt71; GTPase Ypt71	K07897 RAB7A; Ras-related protein Rab-7A 
C    Retromer subcomplex
D      SOMG_04786 vps35; retromer complex subunit Vps35	K18468 VPS35; vacuolar protein sorting-associated protein 35 
D      SOMG_03054 vps29; retromer complex subunit Vps29	K18467 VPS29; vacuolar protein sorting-associated protein 29 
D      SOMG_02769 vps26; retromer complex arrestin related endocytic adaptor ubunit Vps26	K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B 
C    FTS/Hook/FHIP (FHF) complex
C    FERRY complex
C    Rab associated proteins
D      SOMG_00946 bop1; ubiquitin-protein ligase E3, RNF126-like protein	K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27] 
D      SOMG_03860 pik3; phosphatidylinositol 3-kinase Pik3	K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137] 
D      SOMG_05045 pre6; 20S proteasome complex subunit alpha 4 Pre6	K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1] 
D      SOMG_03814 gyp7; Rab GAP Gyp7	K20168 TBC1D15; TBC1 domain family member 15 
D      SOMG_02234 mrs6; Rab geranylgeranyltransferase escort protein Mrs6	K23460 CHM; Rab proteins geranylgeranyltransferase component A 
D      SOMG_04846 bet4; Rab geranylgeranyltransferase alpha subunit Bet4	K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60] 
D      SOMG_01990 ptb1; geranylgeranyltransferase II beta subunit Ptb1	K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] 
D      SOMG_01664 Rab GAP	K20176 SGSM3; small G protein signaling modulator 3 
D      SOMG_01965 gpp74; Golgi phosphoprotein 3 family Vps74	K15620 GOLPH3; golgi phosphoprotein 3 
B  Arf GTPases and associated proteins
C    Arf GTPases
C    BLOC-one-related complex (BORC)
C    N-acetyl transferase complex C (NatC)
D      SOMG_01102 naa30; NatC N-acetyltransferase complex catalytic subunit Naa30	K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256] 
D      SOMG_00429 naa35; NatC N-acetyltransferase complex subunit Naa35	K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit 
D      SOMG_04878 naa38; NatC N-acetyltransferase non-catalytic Sm-like domain subunit Naa38	K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit 
C    Other Arf associated proteins
B  Endosomal sorting complexes required for transport (ESCRT)
C    ESCRT-0 complex
D      SOMG_03717 sst4; sorting receptor for ubiquitinated membrane protein, ESCRT 0 complex subunit Sst4	K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate 
D      SOMG_01389 hse1; ESCRT 0 complex subunit, sorting receptor for ubiquitinated membrane protein, Hse1	K04705 STAM; signal transducing adaptor molecule 
C    ESCRT-I complex
D      SOMG_03511 vps28; ESCRT I complex subunit Vps28	K12184 VPS28; ESCRT-I complex subunit VPS28 
C    ESCRT-II complex
D      SOMG_01309 dot2; ESCRT II complex subunit Dot2	K12188 SNF8; ESCRT-II complex subunit VPS22 
D      SOMG_00116 vps25; ESCRT II complex subunit Vps25	K12189 VPS25; ESCRT-II complex subunit VPS25 
D      SOMG_00487 vps36; ESCRT II complex subunit Vps36	K12190 VPS36; ESCRT-II complex subunit VPS36 
C    ESCRT-III complex
D      SOMG_00601 did2; ESCRT III complex subunit Did2	K12197 CHMP1; charged multivesicular body protein 1 
D      SOMG_03627 did4; ESCRT III complex subunit Did4	K12191 CHMP2A; charged multivesicular body protein 2A 
D      SOMG_02870 vps24; ESCRT III complex subunit Vps24	K12193 VPS24; charged multivesicular body protein 3 
D      SOMG_03092 vps32; ESCRT III complex subunit Vps32	K12194 CHMP4A_B; charged multivesicular body protein 4A/B 
D      SOMG_04792 vps60; vacuolar sorting protein Vps60	K12198 CHMP5; charged multivesicular body protein 5 
D      SOMG_00464 vps20; ESCRT III complex subunit Vps20	K12195 CHMP6; charged multivesicular body protein 6 
D      SOMG_00541 cmp7; ESCRT III complex subunit Cmp7	K15053 CHMP7; charged multivesicular body protein 7 
D      SOMG_01686 vps4; AAA family ATPase Vps4	K12196 VPS4; vacuolar protein-sorting-associated protein 4 
C    ESCRT associated proteins
D      SOMG_01685 alx1; ESCRT-III adaptor Alx1	K12200 PDCD6IP; programmed cell death 6-interacting protein 
B  Tethering complex
C    CORVET complex
D      SOMG_04256 vps3; CORVET complex WD repeat subunit Vps3	K20177 VPS3; vacuolar protein sorting-associated protein 3 
D      SOMG_03303 vps8; CORVET complex WD repeat subunit Vps8	K20178 VPS8; vacuolar protein sorting-associated protein 8 
D      SOMG_03658 vps11; HOPs/CORVET complex ubiquitin protein ligase E3 subunit Vps11	K20179 VPS11; vacuolar protein sorting-associated protein 11 
D      SOMG_02048 vps16; HOPS/CORVET complex subunit Vps16	K20180 VPS16; vacuolar protein sorting-associated protein 16 
D      SOMG_04965 pep3; HOPS/CORVET complex subunit, ubiquitin-protein ligase E3 Pep3/Vps18	K20181 VPS18; vacuolar protein sorting-associated protein 18 
D      SOMG_01139 vps33; HOPS/CORVET complex subunit, vacuolar sorting protein Vps33	K20182 VPS33A; vacuolar protein sorting-associated protein 33A 
C    Hops complex
D      SOMG_03658 vps11; HOPs/CORVET complex ubiquitin protein ligase E3 subunit Vps11	K20179 VPS11; vacuolar protein sorting-associated protein 11 
D      SOMG_02048 vps16; HOPS/CORVET complex subunit Vps16	K20180 VPS16; vacuolar protein sorting-associated protein 16 
D      SOMG_04965 pep3; HOPS/CORVET complex subunit, ubiquitin-protein ligase E3 Pep3/Vps18	K20181 VPS18; vacuolar protein sorting-associated protein 18 
D      SOMG_01139 vps33; HOPS/CORVET complex subunit, vacuolar sorting protein Vps33	K20182 VPS33A; vacuolar protein sorting-associated protein 33A 
D      SOMG_01998 vam6; HOPS complex Rab GEF subunit Vam6	K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39 
D      SOMG_02015 vps41; HOPS complex subunit Vps41	K20184 VPS41; vacuolar protein sorting-associated protein 41 
B  Acidification regulators
C    Rabconnectin-3 complex
D      SOMG_00690 rav1; RAVE complex subunit Rav1	K24155 DMXL; rabconnectin-3a 
C    RAVE complex
D      SOMG_00690 rav1; RAVE complex subunit Rav1	K24155 DMXL; rabconnectin-3a 
D      SOMG_01359 skp1; SCF ubiquitin ligase complex subunit Skp1	K03094 SKP1; S-phase kinase-associated protein 1 
B  Others
C    AP-3 complex
D      SOMG_03868 apl5; AP-3 adaptor complex subunit Apl5	K12396 AP3D; AP-3 complex subunit delta 
D      SOMG_03707 apl6; AP-3 adaptor complex subunit Apl6	K12397 AP3B; AP-3 complex subunit beta 
D      SOMG_01303 apm3; AP-3 adaptor complex subunit Apm3	K12398 AP3M; AP-3 complex subunit mu 
D      SOMG_01817 aps3; AP-3 adaptor complex subunit Aps3	K12399 AP3S; AP-3 complex subunit sigma 
C    BLOC-1 complex
C    BLOC-1 complex (yeast)
C    BLOC-2 complex
C    BLOC-3 complex
C    Ferlins
C    Lysosomal membrane proteins
C    Others
D      SOMG_01556 aut12; autophagy associated protein Aut12	K20195 MON1; vacuolar fusion protein MON1 
D      SOMG_03136 ubp4; ubiquitin C-terminal hydrolase Ubp4	K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12] 
D      SOMG_03622 sst2; AMSH/STAMBP protein-like protein, ubiquitin specific-protease	K11866 STAMBP; STAM-binding protein [EC:3.4.19.12] 
D      SOMG_00417 vps55; vacuolar sorting protein Vps55	K28212 LEPROT; OB-RGRP/VPS55 family protein 
D      SOMG_02644 vps1; dynamin family protein Vps1	K23481 VPS1; vacuolar protein sorting-associated protein 1 
D      SOMG_03164 lvs1; beige protein-like protein Lvs1	K24781 BPH1; beige protein homolog 1 
D      SOMG_04766 ear1; SPRY domain membrane protein, specificity factor required for ubiquitination Ear1	K28544 SSH4; SSH4 family protein 
D      SOMG_01213 rcr1; plasma membrane adaptor for ubiquitin ligase Rcr1	K28545 RCR; protein RCR 
#
A<b>Protein recycling</b>
B  Rab GTPases and associated proteins
C    Rab GTPases
D      SOMG_03505 ypt4; GTPase Ypt4	K07880 RAB4B; Ras-related protein Rab-4B 
D      SOMG_02741 ypt3; Rab11 family GTPase Ypt3	K07904 RAB11A; Ras-related protein Rab-11A 
C    Rab4 associated proteins
D      SOMG_03291 pep7; prevacuole/endosomal FYVE tethering component Pep7	K12481 RBSN; rabenosyn-5 
D      SOMG_02370 atg24; autophagy associated PX/BAR domain sorting nexin Atg24	K17919 SNX4; sorting nexin-4 
C    Rab11 associated proteins
D      SOMG_00087 wdr44; WDR44 family, WD repeat protein	K20241 WDR44; WD repeat-containing protein 44 
D      SOMG_00463 sec13; GATOR2-SEACAT complex/COPII-coated vesicle component/nuclear pore outer ring WD repeat protein Sec13	K14004 SEC13; protein transport protein SEC13 
D      SOMG_04300 sec15; exocyst complex subunit Sec15	K19985 EXOC6; exocyst complex component 6 
D      SOMG_01965 gpp74; Golgi phosphoprotein 3 family Vps74	K15620 GOLPH3; golgi phosphoprotein 3 
C    Other Rab GTPase associated proteins
D      SOMG_01165 vps901; GEF Vps901	K20131 RABGEF1; Rab5 GDP/GTP exchange factor 
D      SOMG_03530 rad51; RecA family recombinase Rad51/Rhp51	K04482 RAD51; DNA repair protein RAD51 
B  Others
C    Glutamate receptor-interacting proteins (GRIPs)
C    GRIP associated proteins
C    EARP complex
D      SOMG_00706 vps52; GARP complex subunit Vps52	K20298 VPS52; vacuolar protein sorting-associated protein 52 
D      SOMG_01950 vps53; GARP complex subunit Vps53	K20299 VPS53; vacuolar protein sorting-associated protein 53 
C    WASH complex
D      SOMG_03761 acp1; F-actin capping protein alpha subunit	K10364 CAPZA; F-actin-capping protein subunit alpha 
D      SOMG_02671 acp2; F-actin capping protein beta subunit Acp2	K10365 CAPZB; F-actin-capping protein subunit beta 
C    Retriever complex
D      SOMG_03054 vps29; retromer complex subunit Vps29	K18467 VPS29; vacuolar protein sorting-associated protein 29 
C    Others
#
A<b>Endosome - Golgi transport</b>
B  Rab GTPases and associated proteins
C    Rab GTPases
C    Rab associated proteins
D      SOMG_01965 gpp74; Golgi phosphoprotein 3 family Vps74	K15620 GOLPH3; golgi phosphoprotein 3 
D      SOMG_00475 Rab GAP	K19951 TBC1D8_9; TBC1 domain family member 8/9 
D      SOMG_00584 vps1301; intermembrane lipid transfer protein, chorein family Vps13a	K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C 
B  Arf GTPases and associated proteins
C    Arf GTPases
D      SOMG_01153 arf1; ADP-ribosylation factor, Arf family Arf1	K07937 ARF1_2; ADP-ribosylation factor 1/2 
C    Arf GTPase associated proteins
D      SOMG_04464 GTPase activating protein	K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 
D      SOMG_03456 glo3; Arf GAP, GTPase activating protein	K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3 
D      SOMG_00400 GTPase activating protein	K12486 SMAP; stromal membrane-associated protein 
D      SOMG_02204 cnt5; Centaurin Cnt5	K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 
D      SOMG_02401 sec71; Arf GEF	K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein 
D      SOMG_02897 sec72; Arf GEF Sec72	K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein 
D      SOMG_00551 gea1; Arf GEF	K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 
B  Tethering complex
C    Conserved oligomeric Golgi (COG) complex
D      SOMG_03549 cog3; Golgi transport complex subunit Cog3	K20290 COG3; conserved oligomeric Golgi complex subunit 3 
D      SOMG_04488 cog4; Golgi transport complex subunit Cog4	K20291 COG4; conserved oligomeric Golgi complex subunit 4 
D      SOMG_01024 cog6; Golgi transport complex peripheral subunit Cog6	K20293 COG6; conserved oligomeric Golgi complex subunit 6 
D      SOMG_00906 cog8; Golgi transport complex subunit Cog8	K20295 COG8; conserved oligomeric Golgi complex subunit 8 
C    GARP complex
D      SOMG_00706 vps52; GARP complex subunit Vps52	K20298 VPS52; vacuolar protein sorting-associated protein 52 
D      SOMG_01950 vps53; GARP complex subunit Vps53	K20299 VPS53; vacuolar protein sorting-associated protein 53 
D      SOMG_04630 vps54; GARP complex subunit Vps54	K17600 VPS54; vacuolar protein sorting-associated protein 54 
C    TRAPP complex II
D      SOMG_00317 bet5; TRAPP I, II and III complex Rab GEF subunit Bet5	K20300 TRAPPC1; trafficking protein particle complex subunit 1 
D      SOMG_03062 tca17; TRAPP complex subunit 2-like Tca17	K20301 TRAPPC2; trafficking protein particle complex subunit 2 
D      SOMG_03126 trs20; TRAPP I,II and III complex subunit Trs20	K20301 TRAPPC2; trafficking protein particle complex subunit 2 
D      SOMG_03534 bet3; TRAPP I, II and III complex Rab GEF subunit Bet3	K20302 TRAPPC3; trafficking protein particle complex subunit 3 
D      SOMG_00483 trs23; TRAPP I, II, and III complex subunit Trs23	K20303 TRAPPC4; trafficking protein particle complex subunit 4 
D      SOMG_00677 trs31; TRAPP I, II and III complex subunit Trs31	K20280 TRAPPC5; trafficking protein particle complex subunit 5 
D      SOMG_03376 trs33; TRAPPI,II,III complex subunit Trs33	K20304 TRAPPC6; trafficking protein particle complex subunit 6 
D      SOMG_00542 trs8501; TRAPP III complex subunit Trs85a	K20305 TRAPPC8; trafficking protein particle complex subunit 8 
D      SOMG_01390 trs8502; TRAPP III complex subunit Trs85b	K20305 TRAPPC8; trafficking protein particle complex subunit 8 
D      SOMG_00814 trs120; TRAPP II complex subunit Trs120	K20306 TRAPPC9; trafficking protein particle complex subunit 9 
D      SOMG_04762 trs130; TRAPP II complex subunit Trs130	K20307 TRAPPC10; trafficking protein particle complex subunit 10 
B  Others
C    AP-1 complex
D      SOMG_04990 apl4; AP-1 adaptor complex gamma subunit Apl4	K12391 AP1G1; AP-1 complex subunit gamma-1 
D      SOMG_01520 apm1; AP-1 adaptor complex mu subunit Apm1	K12393 AP1M; AP-1 complex subunit mu 
C    AP-3 complex
D      SOMG_03868 apl5; AP-3 adaptor complex subunit Apl5	K12396 AP3D; AP-3 complex subunit delta 
D      SOMG_03707 apl6; AP-3 adaptor complex subunit Apl6	K12397 AP3B; AP-3 complex subunit beta 
D      SOMG_01303 apm3; AP-3 adaptor complex subunit Apm3	K12398 AP3M; AP-3 complex subunit mu 
D      SOMG_01817 aps3; AP-3 adaptor complex subunit Aps3	K12399 AP3S; AP-3 complex subunit sigma 
C    AP-4 complex
C    GGA
D      SOMG_00999 gga22; Golgi localized Arf binding gamma-adaptin-like protein Gga22	K12404 GGA; ADP-ribosylation factor-binding protein GGA 
C    Aftiphilin/p200/gamma-synergin complex
C    Others
D      SOMG_01584 pld1; phospholipase D, Pld1	K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4] 
D      SOMG_02266 stt4; 1-phosphatidylinositol 4-kinase Stt4	K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67] 
D      SOMG_04672 its3; 1-phosphatidylinositol-4-phosphate 5-kinase Its3	K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] 
D      SOMG_01185 fab1; 1-phosphatidylinositol-3-phosphate 5-kinase Fab1	K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150] 
D      SOMG_02805 gdt2; Golgi Ca(2+)/H(+) antiporter Gdt2	K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family 
D      SOMG_03276 sphingolipid biosynthesis protein	K23544 SERINC1; serine incorporator 1 
D      SOMG_05007 snx3; sorting nexin Snx3	K17918 SNX3_12; sorting nexin-3/12 
D      SOMG_03345 mvp1; sorting nexin Mvp1	K17922 SNX8; sorting nexin-8 
D      SOMG_02902 GEF	K26678 MON2; protein MON2 
D      SOMG_02080 dop1; Dopey family protein Dop1	K26680 DOP1; protein dopey 
D      SOMG_00361 ftp105; Golgi localized protein, HID1-like protein 3, implicated in vesicle-mediated transport	K27894 HID1; protein HID1 
D      SOMG_02021 HID1-like protein 1, possible Golgi protein (by similarity)	K27894 HID1; protein HID1 
D      SOMG_02644 vps1; dynamin family protein Vps1	K23481 VPS1; vacuolar protein sorting-associated protein 1 
#
A<b>Endoplasmic reticulum (ER) - Golgi transport</b>
B  Forward pathways
C    Coat protein complex II (COP-II)
D      SOMG_00595 sar1; ADP-ribosylation factor Sar1	K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-] 
D      SOMG_00463 sec13; GATOR2-SEACAT complex/COPII-coated vesicle component/nuclear pore outer ring WD repeat protein Sec13	K14004 SEC13; protein transport protein SEC13 
D      SOMG_01246 sec31; COPII-coated vesicle component Sec31	K14005 SEC31; protein transport protein SEC31 
D      SOMG_01030 sec2302; COPII cargo receptor subunit Sec23b	K14006 SEC23; protein transport protein SEC23 
D      SOMG_04317 sec231; COPII cargo receptor subunit Sec23a	K14006 SEC23; protein transport protein SEC23 
D      SOMG_01337 sfb3; COPII-coated vesicle component Sfb3	K14007 SEC24; protein transport protein SEC24 
D      SOMG_02159 zinc finger, Sec23/Sec24-type	K14007 SEC24; protein transport protein SEC24 
D      SOMG_03828 sec24; coincidence detector Sec24/Sfb2 subunit	K14007 SEC24; protein transport protein SEC24 
D      SOMG_01514 spo14; WD repeat protein Spo14	K14003 PREB; prolactin regulatory element-binding protein 
D      SOMG_02433 sec16; multidomain vesicle coat component Sec16	K20353 SEC16; COPII coat assembly protein SEC16 
C    TRAPP complex I
D      SOMG_00317 bet5; TRAPP I, II and III complex Rab GEF subunit Bet5	K20300 TRAPPC1; trafficking protein particle complex subunit 1 
D      SOMG_03062 tca17; TRAPP complex subunit 2-like Tca17	K20301 TRAPPC2; trafficking protein particle complex subunit 2 
D      SOMG_03126 trs20; TRAPP I,II and III complex subunit Trs20	K20301 TRAPPC2; trafficking protein particle complex subunit 2 
D      SOMG_03534 bet3; TRAPP I, II and III complex Rab GEF subunit Bet3	K20302 TRAPPC3; trafficking protein particle complex subunit 3 
D      SOMG_00483 trs23; TRAPP I, II, and III complex subunit Trs23	K20303 TRAPPC4; trafficking protein particle complex subunit 4 
D      SOMG_00677 trs31; TRAPP I, II and III complex subunit Trs31	K20280 TRAPPC5; trafficking protein particle complex subunit 5 
D      SOMG_03376 trs33; TRAPPI,II,III complex subunit Trs33	K20304 TRAPPC6; trafficking protein particle complex subunit 6 
C    p24 family proteins
D      SOMG_01529 erp5; COPII vesicle coat component Erp5/Erp6/Erp1	K20346 TMED4_9_11; p24 family protein alpha 
D      SOMG_04437 emp24; COPII-coated vesicle component Emp24	K20347 TMED2; p24 family protein beta-1 
D      SOMG_02009 erv25; COPII-coated vesicle component Erv25	K20352 TMED10; p24 family protein delta-1 
C    PDI family proteins
D      SOMG_03414 pdi1; ER protein disulfide isomerase	K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1] 
D      SOMG_02659 pdi2; ER protein disulfide isomerase Pdi2	K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1] 
D      SOMG_02727 mpd1; thioredoxin family protein Mpd1	K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1] 
C    Rab GTPases
D      SOMG_01145 ypt1; GTPase Ypt1	K07874 RAB1A; Ras-related protein Rab-1A 
C    Rab associated proteins
D      SOMG_04224 yip3; Rab GTPase binding involved in ER to Golgi vesicle transport Yip3	K20359 RABAC1; PRA1 family protein 1 
D      SOMG_01312 gyp10; Rab GAP Gyp10	K20372 TBC1D20; TBC1 domain family member 20 
D      SOMG_02253 gyp1; Rab GAP Gyp1	K20360 TBC1D22; TBC1 domain family member 2 
D      SOMG_00987 hrf1; COPII-coated vesicle component Hrf1	K20362 YIF1; protein transport protein YIF1 
D      SOMG_02856 yos1; ER to Golgi transport protein Yos1	K22939 IER3IP1; immediate early response 3-interacting protein 1 
D      SOMG_02892 uso1; ER to Golgi tether Uso1	K20361 USO1; intracellular protein transport protein USO1 
C    ER-Golgi intermediate compartment (ERGIC) proteins
D      SOMG_04857 lectin family glycoprotein receptor	K10082 LMAN2; lectin, mannose-binding 2 
D      SOMG_00776 mns1; mannosyl-oligosaccharide 1,2-alpha-mannosidase	K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209] 
D      SOMG_02580 erv41; COPII-coated vesicle component Erv41	K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2 
D      SOMG_03389 erv46; COPII-coated vesicle component Erv46	K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3 
D      SOMG_02943 cor1; cornichon family protein	K20368 CNIH; protein cornichon 
D      SOMG_03787 erv14; cornichon family protein Erv14	K20368 CNIH; protein cornichon 
D      SOMG_04265 erv29; COPII adaptor Erv29	K20369 ERV29; ER-derived vesicles protein 
D      SOMG_01839 bip1; ER heat shock protein BiP	K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10] 
B  Retrieval pathways
C    Coat protein complex I (COP-I)
D      SOMG_02289 cop1; coatomer alpha subunit Cop1	K05236 COPA; coatomer subunit alpha 
D      SOMG_01410 sec26; coatomer beta subunit	K17301 COPB1; coatomer subunit beta 
D      SOMG_03558 sec27; coatomer beta' subunit	K17302 COPB2; coatomer subunit beta' 
D      SOMG_01978 sec21; coatomer gamma subunit Sec21	K17267 COPG; coatomer subunit gamma 
D      SOMG_03182 sec28; coatomer epsilon subunit	K17268 COPE; coatomer subunit epsilon 
D      SOMG_04874 ret3; coatomer zeta subunit	K20472 COPZ; coatomer subunit zeta 
C    NRZ (DSL1) complex
D      SOMG_00934 drp1; RINT1 family protein	K20474 RINT1; RAD50-interacting protein 1 
D      SOMG_03649 sec39; secretory pathway protein Sec39	K20475 SEC39; protein transport protein SEC39 
C    Golgi to ER traffic proteins (GET)
D      SOMG_03429 get1; GET complex (ER membrane insertion) subunit Get1	K22384 GET1; tail-anchored protein insertion receptor 
D      SOMG_03093 get3; GET complex (ER membrane insertion) ATPase subunit Get3	K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-] 
D      SOMG_04299 get4; TRC complex (ER membrane insertion) subunit Get4	K23387 GET4; golgi to ER traffic protein 4 
C    Rab GTPases
C    Rab associated proteins
D      SOMG_03728 ric1; Rab-specific(Ryh1/Ypt6) Ric1-Rgp1 guanyl-nucleotide exchange factor subunit Ric1/Sat4	K20476 RIC1; RAB6A-GEF complex partner protein 1 
D      SOMG_00635 erd2; HDEL receptor	K10949 KDELR; ER lumen protein retaining receptor 
D      SOMG_03291 pep7; prevacuole/endosomal FYVE tethering component Pep7	K12481 RBSN; rabenosyn-5 
D      SOMG_02253 gyp1; Rab GAP Gyp1	K20360 TBC1D22; TBC1 domain family member 2 
B  Others
C    Oxysterol-binding proteins
D      SOMG_03114 osh2; sterol transfer protein Osh2	K20456 OSBP; oxysterol-binding protein 1 
D      SOMG_02011 osh3; sterol transfer protein Osh3	K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7 
D      SOMG_04509 osh6; sterol transfer protein Osh6	K22285 OSBPL8; oxysterol-binding protein-related protein 8 
D      SOMG_00183 osh42; sterol transfer protein Osh42	K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11 
D      SOMG_01448 oss1; sterol transfer protein Oss1	K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11 
D      SOMG_02442 osh41; sterol transfer protein Osh41	K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11 
C    FXYD proteins
C    YIPF proteins
D      SOMG_02088 yip5; Rab GTPase binding Yip5	K22940 YIPF1_2; protein YIPF1/2 
D      SOMG_04455 Rab GTPase binding	K20363 YIPF5_7; protein YIPF5/7 
D      SOMG_03529 Rab GTPase binding	K22943 YIPF6; protein YIPF6 
C    ER membrane protein complex
D      SOMG_03687 emc1; ER membrane protein complex subunit Emc1	K23562 EMC1; ER membrane protein complex subunit 1 
D      SOMG_02232 oca3; ER membrane protein complex subunit Emc2/TPR repeat protein Oca3	K23563 EMC2; ER membrane protein complex subunit 2 
D      SOMG_02470 emc3; ER membrane protein complex subunit Emc3	K23564 EMC3; ER membrane protein complex subunit 3 
D      SOMG_04475 emc4; ER membrane protein complex subunit Emc4	K23565 EMC4; ER membrane protein complex subunit 4 
D      SOMG_04365 emc6; ER membrane protein complex subunit Emc6	K23567 EMC6; ER membrane protein complex subunit 6 
C    SEC61 complex
D      SOMG_00178 sec61; translocon alpha subunit Sec61	K10956 SEC61A; protein transport protein SEC61 subunit alpha 
D      SOMG_03206 sec6102; translocon subunit Sec61-like protein	K10956 SEC61A; protein transport protein SEC61 subunit alpha 
D      SOMG_00125 sbh1; translocon beta subunit Sbh1	K09481 SEC61B; protein transport protein SEC61 subunit beta 
D      SOMG_01662 sss1; translocon gamma subunit Sss1	K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins 
C    TRAP complex
C    Multi-pass translocon (MPT) complex
D      SOMG_02583 ER membrane chaperone for multipass membrane protein	K24962 CCDC47; PAT complex subunit CCDC47 
C    Post-GPI attachment to proteins factors (PGAP)
D      SOMG_02043 bst1; GPI inositol deacylase Bst1	K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-] 
D      SOMG_03663 pga3; GPI-phospholipase A2 activity regulator Pga3	K23553 PGAP3; post-GPI attachment to proteins factor 3 
D      SOMG_00416 GPI-remodelling mannose-ethanolamine phosphate phosphodiesterase	K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-] 
D      SOMG_04675 ted1; GPI-remodelling mannose-ethanolamine phosphate phosphodiesterase Ted1	K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-] 
C    Others
D      SOMG_04940 sly1; SNARE binding protein Sly1	K19998 SCFD1; sec1 family domain-containing protein 1 
D      SOMG_03550 tts1; tetra spanning protein 1, Tts1	K20724 TMEM33; transmembrane protein 33 
D      SOMG_03267 arv1; Arv1-like family protein Arv1	K21848 ARV1; lipid intermediate transporter 
D      SOMG_03702 plasma membrane beta-glucan biosynthesis protein	K21850 KRE6; beta-glucan synthesis-associated protein KRE6 
D      SOMG_01965 gpp74; Golgi phosphoprotein 3 family Vps74	K15620 GOLPH3; golgi phosphoprotein 3 
D      SOMG_04221 ins1; INSIG domain protein	K26681 INSIG; insulin-induced protein 
D      SOMG_01754 sey1; ER fusion GTPase, atlastin Sey1	K22698 SEY1; protein SEY1 [EC:3.6.5.-] 
#
A<b>Autophagy</b>
B  Autophagosome formation proteins
C    ULK complex
D      SOMG_03598 atg13; autophagy associated protein Atg13	K08331 ATG13; autophagy-related protein 13 
D      SOMG_03693 atg101; autophagy associated HORMA domain protein Atg101	K19730 ATG101; autophagy-related protein 101 
C    Atg1 complex
D      SOMG_04399 atg1; autophagy serine/threonine protein kinase Atg1	K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1] 
D      SOMG_03598 atg13; autophagy associated protein Atg13	K08331 ATG13; autophagy-related protein 13 
D      SOMG_01855 atg17; autophagy associated protein kinase activator Atg17	K08329 ATG17; autophagy-related protein 17 
C    PI3K complex
D      SOMG_03860 pik3; phosphatidylinositol 3-kinase Pik3	K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137] 
D      SOMG_02282 vps15; serine/threonine protein kinase Vps15	K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] 
D      SOMG_01934 atg6; autophagy associated beclin family protein Atg6	K08334 BECN; beclin 
C    ATG9 transmembrane protein
D      SOMG_01101 atg9; autophagy associated phospholipid scramblase Atg9	K17907 ATG9; autophagy-related protein 9 
C    Atg18-Atg2 complex
D      SOMG_00298 atg1801; autophagy associated WD repeat protein Atg18a	K17908 WIPI1_2; autophagy-related protein 18 
D      SOMG_02182 atg2; autophagy associated intermembrane lipid transfer protein Atg2	K17906 ATG2; autophagy-related protein 2 
C    Atg12 conjugation proteins
D      SOMG_02735 atg12; autophagy associated ubiquitin-like protein modifier Atg12	K08336 ATG12; ubiquitin-like protein ATG12 
D      SOMG_01194 atg7; E1 Atg8 and Atg12 E1 activating enzyme Atg7	K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7 
D      SOMG_02086 atg10; Atg12 conjugating enzyme Atg10	K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10 
D      SOMG_00120 atg5; autophagy associated protein Atg5	K08339 ATG5; autophagy-related protein 5 
C    Atg8 conjugation proteins
D      SOMG_00632 atg8; autophagy associated protein Atg8	K08341 GABARAP; GABA(A) receptor-associated protein 
D      SOMG_03620 atg4; Atg8 deconjugator Atg4	K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-] 
D      SOMG_01194 atg7; E1 Atg8 and Atg12 E1 activating enzyme Atg7	K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7 
D      SOMG_00490 atg3; autophagy associated protein Atg3	K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3 
B  Cytoplasm to vacuolar targeting (CVT) pathway
C    Selective cargos
D      SOMG_00235 ams1; Class II alpha-mannosidase, subtype C, Ams1	K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24] 
D      SOMG_03815 ape4; aspartyl metalloaminopeptidase Ape4	K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21] 
C    Cargo receptors
C    Scaffold protein
C    Other Cvt associated proteins
D      SOMG_03803 snx41; PX domain sorting nexin Snx41	K21996 SNX41_42; sorting nexin-41/42 
D      SOMG_02370 atg24; autophagy associated PX/BAR domain sorting nexin Atg24	K17919 SNX4; sorting nexin-4 
D      SOMG_01787 atg15; autophagy associated lysophospholipase Atg15	K17900 ATG15; lipase ATG15 [EC:3.1.1.3] 
D      SOMG_02324 vac8; vacuolar protein-membrane adaptor Vac8	K08332 VAC8; vacuolar protein 8 
B  Mitophagy
C    Cargo receptors
C    Scaffold proteins
C    PINK1-Parkin associated proteins
D      SOMG_02321 fzo1; mitochondrial dynamin family fusion GTPase (mitofusin) Fzo1	K06030 MFN2; mitofusin 2 [EC:3.6.5.-] 
C    Other mitophagy associated  proteins
D      SOMG_02076 hxk1; hexokinase 1	K00844 HK; hexokinase [EC:2.7.1.1] 
D      SOMG_03633 hxk2; hexokinase 2	K00844 HK; hexokinase [EC:2.7.1.1] 
D      SOMG_04089 inh1; mitochondrial proton-transporting ATP synthase inhibitor Inh1	K22255 ATPIF1; ATPase inhibitor, mitochondrial 
D      SOMG_01270 tom7; mitochondrial TOM complex subunit Tom7	K17771 TOM7; mitochondrial import receptor subunit TOM7 
B  Pexophagy
C    Selective cargos
D      SOMG_03950 pex3; peroxin-3 peroxisome-plasma membrane adaptor Pex3	K13336 PEX3; peroxin-3 
C    Cargo receptors
C    Other pexophagy associated proteins
D      SOMG_00380 pex6; peroxin-6 ATPase subunit	K13339 PEX6; peroxin-6 
B  Aggrephagy
C    Cargo receptors
C    Scaffold proteins
C    Other aggrephagy associated proteins
D      SOMG_01892 cdc48; AAA family ATPase involved in ubiquitin-mediated protein degradation Cdc48	K13525 VCP; transitional endoplasmic reticulum ATPase 
D      SOMG_02175 clr3; histone deacetylase (class II) Clr3	K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
B  Xenophagy
C    Cargo receptors
C    Other xenophagy associated proteins
B  ER-phagy
C    ER-phagy recepters
D      SOMG_03290 sec62; ER protein translocation subcomplex subunit Sec62	K12275 SEC62; translocation protein SEC62 
C    Other ER-phagy associated proteins
D      SOMG_02694 cnx1; calnexin Cnx1	K08054 CANX; calnexin 
D      SOMG_04704 dap1; cytochrome P450 regulator Dap1	K17278 PGRMC1_2; membrane-associated progesterone receptor component 
C    ER stress-related proteins
D      SOMG_01839 bip1; ER heat shock protein BiP	K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10] 
D      SOMG_00325 tif211; translation initiation factor eIF2 alpha subunit	K03237 EIF2S1; translation initiation factor 2 subunit 1 
B  Chaperone mediated autophagy (CMA)
C    Selective cargos
D      SOMG_01857 caa1; cytoplasmic aspartate aminotransferase Caa1	K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] 
D      SOMG_02326 gpd3; glyceraldehyde 3-phosphate dehydrogenase Gpd3	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 
D      SOMG_02570 tdh1; glyceraldehyde-3-phosphate dehydrogenase Tdh1	K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 
D      SOMG_03971 gpm1; monomeric 2,3-bisphosphoglycerate (BPG)-dependent phosphoglycerate mutase (PGAM), Gpm1	K01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] 
D      SOMG_04586 pyk1; pyruvate kinase	K00873 PK; pyruvate kinase [EC:2.7.1.40] 
D      SOMG_00757 dsk2; UBA domain protein Dph1/Dsk2	K04523 UBQLN; ubiquilin 
C    Cargo receptors
C    Chaperones
D      SOMG_01376 sks2; heat shock protein, Hsp70 family, ribosome associated Sks2	K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
D      SOMG_02777 ssa1; Hsp70 family heat shock protein Ssa1	K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
D      SOMG_04935 ssa2; Hsp70 family heat shock protein Ssa2	K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8 
D      SOMG_04605 hsp90; Hsp90 chaperone	K04079 HSP90A; molecular chaperone HtpG 
C    Co-chaperones
C    Other CMA associated proteins
D      SOMG_02306 tef103; translation elongation factor EF-1 alpha Ef1a-c	K03231 EEF1A; elongation factor 1-alpha 
D      SOMG_04173 tef101; translation elongation factor EF-1 alpha Ef1a-a	K03231 EEF1A; elongation factor 1-alpha 
D      SOMG_04683 tef102; translation elongation factor EF-1 alpha Ef1a-b	K03231 EEF1A; elongation factor 1-alpha 
D      SOMG_04667 cpy1; vacuolar carboxypeptidase Y	K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5] 
B  Other autophagy associated proteins
C    RNautophagy/DNautophagy
C    Micronucleophagy
D      SOMG_02324 vac8; vacuolar protein-membrane adaptor Vac8	K08332 VAC8; vacuolar protein 8 
C    Midbophagy
C    Glycophagy
C    TRIM-directed selective autophagy
C    ER-mitochondria tethering complex
D      SOMG_02321 fzo1; mitochondrial dynamin family fusion GTPase (mitofusin) Fzo1	K06030 MFN2; mitofusin 2 [EC:3.6.5.-] 
C    mTORC1 complex
D      SOMG_01073 tor1; TORC2 serine/threonine protein kinase Tor1	K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1] 
D      SOMG_01455 tor2; TORC1 serine/threonine protein kinase Tor2	K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1] 
D      SOMG_00851 pop3; TORC1/2 complex WD repeat protein Pop3/Wat1/Lst8	K08266 MLST8; target of rapamycin complex subunit LST8 
D      SOMG_01977 mip1; TORC1 substrate adaptor	K07204 RAPTOR; regulatory associated protein of mTOR 
C    mTORC2 complex
D      SOMG_01073 tor1; TORC2 serine/threonine protein kinase Tor1	K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1] 
D      SOMG_01455 tor2; TORC1 serine/threonine protein kinase Tor2	K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1] 
D      SOMG_00851 pop3; TORC1/2 complex WD repeat protein Pop3/Wat1/Lst8	K08266 MLST8; target of rapamycin complex subunit LST8 
D      SOMG_03857 sin1; MAP kinase and TOR substrate adaptor Sin1	K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1 
D      SOMG_02627 ste20; Rictor-like protein	K08267 RICTOR; rapamycin-insensitive companion of mTOR 
D      SOMG_04780 bit61; Protor-like protein	K25577 BIT61_2; target of rapamycin complex 2 subunit BIT61/BIT2 
C    SEACIT/GATOR1 complex
D      SOMG_00514 iml1; GATOR1-SEACIT GTPase complex subunit Iml1	K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5 
D      SOMG_03710 npr2; GATOR1-SEACIT GTPase complex subunit Npr2	K20405 NPRL2; nitrogen permease regulator 2 
D      SOMG_03435 npr3; GATOR1-SEACIT GTPase complex subunit Npr3	K20406 NPRL3; nitrogen permease regulator 3 
C    SEACAT/GATOR2 complex
D      SOMG_03636 sea2; GATOR2-SEACAT complex WD repeat subunit Sea2	K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24 
D      SOMG_04012 sea3; GATOR2-SEACAT complex/GATOR1-SEACIT GTPase complex ubiquitin-protein ligase E3 subunit Sea3	K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59 
D      SOMG_03591 sea4; GATOR2-SEACAT complex ubiquitin-protein ligase E3 subunit Sea4	K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS 
D      SOMG_02823 seh1; GATOR2-SEACAT complex WD repeat subunit Seh1	K14299 SEH1; nucleoporin SEH1 
D      SOMG_00463 sec13; GATOR2-SEACAT complex/COPII-coated vesicle component/nuclear pore outer ring WD repeat protein Sec13	K14004 SEC13; protein transport protein SEC13 
C    KICSTOR complex
C    Rab GTPases
D      SOMG_01145 ypt1; GTPase Ypt1	K07874 RAB1A; Ras-related protein Rab-1A 
D      SOMG_02875 ypt2; GTPase Ypt2	K07901 RAB8A; Ras-related protein Rab-8A 
C    Rab associated proteins
C    Others
D      SOMG_01494 ppa2; serine/threonine protein phosphatase PP2A catalytic subunit Ppa2	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
D      SOMG_03655 ppa1; serine/threonine protein phosphatase PP2A catalytic subunit Ppa1	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
D      SOMG_04396 tap42; TAP42 family TORC1 signaling protein Tap42	K17606 IGBP1; immunoglobulin-binding protein 1 
D      SOMG_03146 vps38; phophatidylinositol 3-kinase complex subunit Vps38	K21249 UVRAG; UV radiation resistance-associated gene protein 
D      SOMG_01693 atg22; vacuolar amino acid transmembrane transporter Atg22	K06902 UMF1; MFS transporter, UMF1 family 
D      SOMG_03252 avt3; vacuolar amino acid transmembrane transporter Avt3	K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter) 
D      SOMG_04146 vma21; ER membrane V-ATPase assembly factor Vma21	K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21 
#
A<b>Others</b>
B  NADPH oxidases (Nox) and associated proteins
C    NADPH oxidases
C    Nox associated proteins
B  Actin-binding proteins
C    Myosins
D      SOMG_01411 myo1; myosin type I	K10356 MYO1; myosin I 
D      SOMG_01115 myo51; myosin type V	K10357 MYO5; myosin V 
D      SOMG_04971 myo52; myosin type V	K10357 MYO5; myosin V 
C    Arp2/3 complex
D      SOMG_02220 arc1; ARP2/3 actin-organizing complex subunit Sop2	K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B 
D      SOMG_02372 arc2; ARP2/3 actin-organizing complex subunit Arc34	K05758 ARPC2; actin related protein 2/3 complex, subunit 2 
D      SOMG_01057 arc3; ARP2/3 actin-organizing complex subunit Arc21	K05756 ARPC3; actin related protein 2/3 complex, subunit 3 
D      SOMG_00801 arc4; ARP2/3 actin-organizing complex subunit Arc4	K05755 ARPC4; actin related protein 2/3 complex, subunit 4 
D      SOMG_02801 arc5; ARP2/3 actin-organizing complex subunit Arc5	K05754 ARPC5; actin related protein 2/3 complex, subunit 5 
D      SOMG_03844 arp2; ARP2/3 actin-organizing complex subunit Arp2	K17260 ACTR2; actin-related protein 2 
D      SOMG_03592 arp3; Arp2/3 protein complex, actin-like protein subunit Arp3	K18584 ACTR3; actin-related protein 3 
C    Nucleation-promoting factors (NPFs)
D      SOMG_03606 wsp1; WASp-like protein	K23612 WASL; neural Wiskott-Aldrich syndrome protein 
D      SOMG_04003 abp1; cofilin/tropomyosin family	K20520 DBNL; drebrin-like protein 
D      SOMG_02923 pan1; actin cortical patch component, with EF hand and WH2 motif Panl	K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1 
D      SOMG_03224 hob1; BAR adaptor protein Hob1	K12562 AMPH; amphiphysin 
D      SOMG_03329 shd1; cytoskeletal protein binding protein Sla1 family, Shd1	K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1 
D      SOMG_00520 lsb1; Wiskott-Aldrich syndrome-like protein binding protein Lsb1	K20522 LSB1_2; LAS seventeen-binding protein 1/2 
D      SOMG_01651 lsb4; actin cortical patch component Lsb4	K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1 
D      SOMG_00594 lsb5; actin cortical patch component Lsb5	K20524 LSB5; LAS seventeen-binding protein 5 
D      SOMG_02042 lsb6; 1-phosphatidylinositol 4-kinase Lsb6	K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67] 
C    Others
D      SOMG_03671 cdc3; profilin	K05759 PFN; profilin 
D      SOMG_03818 adf1; actin depolymerizing factor, cofilin	K05765 CFL; cofilin 
D      SOMG_04217 cap1; adenylyl cyclase-associated protein Cap1	K17261 CAP1_2; adenylyl cyclase-associated protein 
D      SOMG_03635 stg1; SM22/transgelin-like actin modulating protein Stg1	K20526 TAGLN; transgelin 
B  Mucins
C    Membrane bound mucins
C    Secretory mucins
B  MARVEL domain-containing proteins
B  Specific organelles associated proteins
C    Melanosome
C    Auto phagosome
C    Lipid droplets
D      SOMG_03431 fit1; ER membrane CoA pyrophosphatase (FIT) family lipid storage protein Fit1	K28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-] 
C    Mitochondrion
B  Rho GTPase associated proteins
C    Rho GTPase-activating proteins
D      SOMG_02134 rga7; RhoGAP Rga7	K20643 RGD1; Rho GTPase-activating protein RGD1 
D      SOMG_00763 rga2; RhoGAP Rga2	K08773 RALBP1; RalA-binding protein 1 
C    Rho guanine nucleotide exchange factors (GEFs)
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#Last updated: October 3, 2025