+E	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Messenger RNA Biogenesis - Saprolegnia parasitica</h2>
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A<b>Eukaryotic type</b>
B  mRNA processing factors
C    5' end processing
D      Capping factors
E        SPRG_14888 hypothetical protein	K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] 
E        SPRG_01805 CMGC/CDK/CDK5 protein kinase	K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22] 
E        SPRG_05845 CMGC/CDK protein kinase	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        SPRG_11995 CMGC/CDK/CDK7 protein kinase	K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] 
E        SPRG_13665 hypothetical protein	K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57] 
E        SPRG_15961 hypothetical protein	K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57] 
D      Cap binding complex
E        SPRG_07307 hypothetical protein	K12882 NCBP1; nuclear cap-binding protein subunit 1 
E        SPRG_12196 hypothetical protein	K12883 NCBP2; nuclear cap-binding protein subunit 2 
C    3' end processing
D      Pre-mRNA cleavage factor Im (CFIm)
D      Pre-mRNA cleavage factor IIm (CFIIm)
E        SPRG_08536 hypothetical protein	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        SPRG_17767 hypothetical protein	K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] 
E        SPRG_20790 hypothetical protein	K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 
D      Cleavage and polyadenylation specificity factor (CPSF) complex
E        SPRG_19816 hypothetical protein	K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1 
E        SPRG_07999 hypothetical protein	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        SPRG_12757 hypothetical protein	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        SPRG_16972 hypothetical protein	K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4 
E        SPRG_14839 hypothetical protein	K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 
E        SPRG_14956 hypothetical protein	K15542 PFS2; polyadenylation factor subunit 2 
E        SPRG_09323 hypothetical protein	K14962 WDR82; COMPASS component SWD2 
E        SPRG_00117 serine/threonine-protein phosphatase PP1-beta catalytic subunit	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        SPRG_09807 serine/threonine-protein phosphatase PP1	K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] 
E        SPRG_15877 hypothetical protein	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
E        SPRG_17059 hypothetical protein	K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] 
D      Cleavage stimulation factor (CSTF) complex
E        SPRG_10503 hypothetical protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        SPRG_04212 hypothetical protein	K14408 CSTF3; cleavage stimulation factor subunit 3 
E        SPRG_04950 hypothetical protein	K06100 SYMPK; symplekin 
D      U7-dependent histone pre-mRNA processing factors
E        SPRG_04704 hypothetical protein	K11086 SNRPB; small nuclear ribonucleoprotein B and B' 
E        SPRG_07720 hypothetical protein	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        SPRG_09658 hypothetical protein	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        SPRG_18352 hypothetical protein	K11088 SNRPD3; small nuclear ribonucleoprotein D3 
E        SPRG_03527 small nuclear ribonucleoprotein E	K11097 SNRPE; small nuclear ribonucleoprotein E 
E        SPRG_05695 small nuclear ribonucleoprotein F	K11098 SNRPF; small nuclear ribonucleoprotein F 
E        SPRG_11492 hypothetical protein	K11099 SNRPG; small nuclear ribonucleoprotein G 
E        SPRG_04119 hypothetical protein	K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10 
E        SPRG_06491 hypothetical protein	K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11 
E        SPRG_07999 hypothetical protein	K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2 
E        SPRG_12757 hypothetical protein	K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] 
E        SPRG_10503 hypothetical protein	K14407 CSTF2; cleavage stimulation factor subunit 2 
E        SPRG_04950 hypothetical protein	K06100 SYMPK; symplekin 
E        SPRG_01921 hypothetical protein	K18710 SLBP; histone RNA hairpin-binding protein 
D      DRB sensitivity inducing factor (DSIF) complex
E        SPRG_14342 hypothetical protein	K15171 SUPT4H1; transcription elongation factor SPT4 
E        SPRG_17218 hypothetical protein	K15171 SUPT4H1; transcription elongation factor SPT4 
E        SPRG_14336 hypothetical protein	K15172 SUPT5H; transcription elongation factor SPT5 
D      N6-methyltransferase complex
E        SPRG_03347 hypothetical protein	K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348] 
E        SPRG_10355 hypothetical protein	K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit 
E        SPRG_09490 hypothetical protein	K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346] 
D      Poly(A) addition factors
E        SPRG_01650 hypothetical protein	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
E        SPRG_06753 hypothetical protein	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
E        SPRG_14011 hypothetical protein	K14376 PAP; poly(A) polymerase [EC:2.7.7.19] 
E        SPRG_09053 hypothetical protein	K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19] 
E        SPRG_15135 hypothetical protein	K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19] 
D      Negative regulators of mRNA 3' end processing
E        SPRG_12252 hypothetical protein	K13192 RBM26; RNA-binding protein 26 
C    Other processing factors
D      SPRG_04668 hypothetical protein	K13102 KIN; DNA/RNA-binding protein KIN17 
D      SPRG_01104 hypothetical protein	K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-] 
D      SPRG_05887 hypothetical protein	K27103 SRRT; serrate RNA effector molecule 
B  mRNA surveillance and transport factors
C    Transport factors
D      EJC complex
E        SPRG_04993 hypothetical protein	K12876 RBM8A; RNA-binding protein 8A 
E        SPRG_07065 mago nashi 2	K12877 MAGOH; protein mago nashi 
E        SPRG_10255 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        SPRG_06983 DEAD-box ATP-dependent RNA helicase 15	K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7] 
E        SPRG_09992 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        SPRG_19954 hypothetical protein	K14324 SAP18; histone deacetylase complex subunit SAP18 
E        SPRG_09629 hypothetical protein	K13114 PNN; pinin 
E        SPRG_02277 hypothetical protein	K14325 RNPS1; RNA-binding protein with serine-rich domain 1 
E        SPRG_06043 hypothetical protein	K13171 SRRM1; serine/arginine repetitive matrix protein 1 
D      TREX complex
E        SPRG_04163 hypothetical protein	K12878 THOC1; THO complex subunit 1 
E        SPRG_02986 hypothetical protein	K12879 THOC2; THO complex subunit 2 
E        SPRG_13939 hypothetical protein	K12880 THOC3; THO complex subunit 3 
E        SPRG_10255 hypothetical protein	K12881 THOC4; THO complex subunit 4 
E        SPRG_03012 hypothetical protein	K13174 THOC5; THO complex subunit 5 
E        SPRG_04669 hypothetical protein	K13176 THOC7; THO complex subunit 7 
D      TREX-2 complex
E        SPRG_15096 hypothetical protein	K23801 PCID2; nuclear mRNA export protein PCID2/THP1 
E        SPRG_19533 hypothetical protein	K10881 SHFM1; 26 proteasome complex subunit DSS1 
E        SPRG_15358 hypothetical protein	K11368 ENY2; enhancer of yellow 2 transcription factor 
E        SPRG_17033 hypothetical protein	K11368 ENY2; enhancer of yellow 2 transcription factor 
E        SPRG_07678 hypothetical protein	K16466 CETN3; centrin-3 
D      Nuclear pore complex
E        SPRG_08832 hypothetical protein	K09291 TPR; nucleoprotein TPR 
E        SPRG_06549 hypothetical protein	K14298 RAE1; mRNA export factor 
E        SPRG_03160 hypothetical protein	K14004 SEC13; protein transport protein SEC13 
E        SPRG_11946 hypothetical protein	K14004 SEC13; protein transport protein SEC13 
E        SPRG_07755 hypothetical protein	K14304 NUP85; nuclear pore complex protein Nup85 
E        SPRG_14805 hypothetical protein	K14305 NUP43; nuclear pore complex protein Nup43 
E        SPRG_19970 hypothetical protein	K14308 NUP54; nuclear pore complex protein Nup54 
E        SPRG_05836 hypothetical protein	K14306 NUP62; nuclear pore complex protein Nup62 
E        SPRG_18530 hypothetical protein	K14306 NUP62; nuclear pore complex protein Nup62 
E        SPRG_11231 hypothetical protein	K14309 NUP93; nuclear pore complex protein Nup93 
E        SPRG_08991 hypothetical protein	K14297 NUP98; nuclear pore complex protein Nup98-Nup96 
E        SPRG_13736 hypothetical protein	K14301 NUP107; nuclear pore complex protein Nup107 
E        SPRG_04792 hypothetical protein	K14300 NUP133; nuclear pore complex protein Nup133 
E        SPRG_04860 hypothetical protein	K14296 NUP153; nuclear pore complex protein Nup153 
E        SPRG_04478 hypothetical protein	K14312 NUP155; nuclear pore complex protein Nup155 
E        SPRG_20666 hypothetical protein	K14312 NUP155; nuclear pore complex protein Nup155 
E        SPRG_09643 hypothetical protein	K14313 NUP35; nuclear pore complex protein Nup53 
E        SPRG_19283 hypothetical protein	K14310 NUP205; nuclear pore complex protein Nup205 
E        SPRG_18886 hypothetical protein	K14307 NUPL1; nucleoporin p58/p45 
E        SPRG_05133 hypothetical protein	K14299 SEH1; nucleoporin SEH1 
E        SPRG_15427 hypothetical protein	K18716 NUP42; nucleoporin NUP42 
E        SPRG_03685 hypothetical protein	K18719 NUP82; nucleoporin NUP82 
E        SPRG_05771 hypothetical protein	K18722 NUP2; nucleoporin NUP2 
E        SPRG_07678 hypothetical protein	K16466 CETN3; centrin-3 
E        SPRG_12004 hypothetical protein	K18723 GLE1; nucleoporin GLE1 
D      Ran-mediated transport factors
E        SPRG_01592 GTP-binding nuclear protein Ran	K07936 RAN; GTP-binding nuclear protein Ran 
E        SPRG_11233 hypothetical protein	K07936 RAN; GTP-binding nuclear protein Ran 
E        SPRG_11234 hypothetical protein	K07936 RAN; GTP-binding nuclear protein Ran 
E        SPRG_16874 hypothetical protein	K07936 RAN; GTP-binding nuclear protein Ran 
E        SPRG_19245 hypothetical protein	K18726 FAF2; FAS-associated factor 2 
E        SPRG_00678 cell division cycle protein 48	K13525 VCP; transitional endoplasmic reticulum ATPase 
E        SPRG_01231 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        SPRG_03540 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        SPRG_06326 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        SPRG_08839 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        SPRG_08847 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        SPRG_19800 hypothetical protein	K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-] 
E        SPRG_07880 hypothetical protein	K14290 XPO1; exportin-1 
E        SPRG_19511 hypothetical protein	K18460 XPO7; exportin-7 
E        SPRG_08465 hypothetical protein	K14319 RANGAP1; Ran GTPase-activating protein 1 
D      eIF4F and regulatory proteins
E        SPRG_00815 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_06037 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_10455 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_13708 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_14886 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_16575 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_00922 ATP-dependent RNA helicase eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        SPRG_13388 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        SPRG_20125 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        SPRG_20698 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        SPRG_19104 hypothetical protein	K24086 EIF4H; translation initiation factor 4H 
E        SPRG_01662 hypothetical protein	K18729 ANGEL; protein angel 
E        SPRG_10198 hypothetical protein	K18729 ANGEL; protein angel 
E        SPRG_02350 hypothetical protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        SPRG_17884 hypothetical protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        SPRG_07502 hypothetical protein	K13133 GEMIN5; gem associated protein 5 
E        SPRG_15570 hypothetical protein	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        SPRG_15352 hypothetical protein	K13126 PABPC; polyadenylate-binding protein 
E        SPRG_06913 hypothetical protein	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        SPRG_14378 hypothetical protein	K24272 DENR; density-regulated protein 
D      APOBEC1-ACF complex
D      Other transport factors
E        SPRG_06287 hypothetical protein	K14294 WIBG; partner of Y14 and mago 
E        SPRG_05436 hypothetical protein	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        SPRG_21082 hypothetical protein	K14411 MSI; RNA-binding protein Musashi 
E        SPRG_03004 hypothetical protein	K14416 HBS1; elongation factor 1 alpha-like protein 
E        SPRG_05006 translation factor pelota	K06965 PELO; protein pelota 
E        SPRG_02264 hypothetical protein	K14396 PABPN1; polyadenylate-binding protein 2 
E        SPRG_11246 hypothetical protein	K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7] 
E        SPRG_19174 hypothetical protein	K12867 SYF1; pre-mRNA-splicing factor SYF1 
E        SPRG_19024 hypothetical protein	K18732 SARNP; SAP domain-containing ribonucleoprotein 
E        SPRG_10442 hypothetical protein	K11493 RCC1; regulator of chromosome condensation 
E        SPRG_01973 hypothetical protein	K23802 LENG8; SAC3 family protein LENG8/THP3 
C    Surveillance factors
D      Surveillance complex
E        SPRG_02251 eukaryotic peptide chain release factor subunit 1	K03265 ETF1; peptide chain release factor subunit 1 
E        SPRG_04352 hypothetical protein	K03267 ERF3; peptide chain release factor subunit 3 
E        SPRG_08789 hypothetical protein	K14327 UPF2; regulator of nonsense transcripts 2 
D      Protein phosphatase 2A
E        SPRG_06497 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        SPRG_13555 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] 
E        SPRG_05829 hypothetical protein	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        SPRG_07324 hypothetical protein	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        SPRG_19729 hypothetical protein	K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A 
E        SPRG_07315 hypothetical protein	K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B 
E        SPRG_03354 hypothetical protein	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        SPRG_05536 hypothetical protein	K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B'' 
E        SPRG_01612 hypothetical protein	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        SPRG_07186 hypothetical protein	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        SPRG_14312 hypothetical protein	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
E        SPRG_20630 hypothetical protein	K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B' 
D      Other surveillance factors
E        SPRG_22295 hypothetical protein	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        SPRG_04472 hypothetical protein	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        SPRG_03189 hypothetical protein	K18735 SMG9; protein SMG9 
E        SPRG_13658 hypothetical protein	K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2 
E        SPRG_14646 hypothetical protein	K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2 
E        SPRG_06842 hypothetical protein	K24887 GTPBP1; GTP-binding protein 1 
C    Factors involved in mRNA localization
D      Cargo complex
E        SPRG_08449 hypothetical protein	K14844 PUF6; pumilio homology domain family member 6 
E        SPRG_01581 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_02231 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_02517 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_02722 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03391 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03400 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03401 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03402 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05263 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05311 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05392 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05632 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_08074 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_08351 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_12183 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_14367 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_14408 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_19487 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20560 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20561 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20562 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20600 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20988 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_21053 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_22058 hypothetical protein	K10357 MYO5; myosin V 
D      Factors that have mRNA localization signals
D      Trans-acting binding proteins
E        SPRG_02882 hypothetical protein	K13210 FUBP; far upstream element-binding protein 
E        SPRG_10439 elongation factor 1-alpha 1	K03231 EEF1A; elongation factor 1-alpha 
E        SPRG_00875 hypothetical protein	K03233 EEF1G; elongation factor 1-gamma 
E        SPRG_05433 hypothetical protein	K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1 
E        SPRG_19574 hypothetical protein	K13218 PTBP1; polypyrimidine tract-binding protein 1 
D      Other mRNA localization factors
E        SPRG_02350 hypothetical protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
E        SPRG_17884 hypothetical protein	K05749 CYFIP; cytoplasmic FMR1 interacting protein 
C    mRNA cycle factors
D      Common to processing body (P body) and stress granule
E        SPRG_14369 hypothetical protein	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
E        SPRG_07370 hypothetical protein	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        SPRG_21025 hypothetical protein	K11593 ELF2C; eukaryotic translation initiation factor 2C 
E        SPRG_00815 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_06037 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_10455 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_13708 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_14886 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_16575 hypothetical protein	K03259 EIF4E; translation initiation factor 4E 
E        SPRG_15570 hypothetical protein	K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7] 
E        SPRG_06340 DEAD-box ATP-dependent RNA helicase 8	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
E        SPRG_06980 hypothetical protein	K18749 LSM14; protein LSM14 
E        SPRG_02568 hypothetical protein	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        SPRG_12317 hypothetical protein	K18422 MOV10; helicase MOV-10 [EC:5.6.2.5] 
E        SPRG_07446 hypothetical protein	K18752 TNPO1; transportin-1 
E        SPRG_22295 hypothetical protein	K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1] 
E        SPRG_04472 hypothetical protein	K11124 SMG6; protein SMG6 [EC:3.1.-.-] 
E        SPRG_03462 hypothetical protein	K18753 ZFP36L; butyrate response factor 
E        SPRG_05482 hypothetical protein	K18753 ZFP36L; butyrate response factor 
E        SPRG_14542 hypothetical protein	K18753 ZFP36L; butyrate response factor 
E        SPRG_05436 hypothetical protein	K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3 
E        SPRG_00666 AGC/PKA protein kinase	K04345 PKA; protein kinase A [EC:2.7.11.11] 
E        SPRG_05964 AGC/PKA protein kinase	K04345 PKA; protein kinase A [EC:2.7.11.11] 
D      P-body specific factors
E        SPRG_03036 hypothetical protein	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        SPRG_19997 hypothetical protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        SPRG_02015 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        SPRG_10785 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        SPRG_13150 hypothetical protein	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        SPRG_04072 hypothetical protein	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        SPRG_02970 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        SPRG_15839 hypothetical protein	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        SPRG_11298 hypothetical protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
E        SPRG_01581 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_02231 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_02517 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_02722 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03391 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03400 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03401 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_03402 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05263 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05311 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05392 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_05632 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_08074 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_08351 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_12183 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_14367 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_14408 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_19487 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20560 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20561 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20562 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20600 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_20988 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_21053 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_22058 hypothetical protein	K10357 MYO5; myosin V 
E        SPRG_04481 tubulin alpha chain	K07374 TUBA; tubulin alpha 
E        SPRG_04482 tubulin alpha chain	K07374 TUBA; tubulin alpha 
E        SPRG_07894 tubulin alpha-1 chain	K07374 TUBA; tubulin alpha 
E        SPRG_09503 tubulin alpha chain	K07374 TUBA; tubulin alpha 
E        SPRG_07502 hypothetical protein	K13133 GEMIN5; gem associated protein 5 
E        SPRG_06770 hypothetical protein	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        SPRG_05301 hypothetical protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        SPRG_14773 hypothetical protein	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        SPRG_05320 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        SPRG_12545 hypothetical protein	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        SPRG_12941 hypothetical protein	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        SPRG_00768 hypothetical protein	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        SPRG_16793 hypothetical protein	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        SPRG_00556 hypothetical protein	K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-] 
E        SPRG_00453 hypothetical protein	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        SPRG_11569 hypothetical protein	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
E        SPRG_08789 hypothetical protein	K14327 UPF2; regulator of nonsense transcripts 2 
E        SPRG_15027 hypothetical protein	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
E        SPRG_20943 hypothetical protein	K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7 
E        SPRG_12063 hypothetical protein	K20102 YTHDF; YTH domain-containing family protein 
D      Stress granule specific factors
E        SPRG_15352 hypothetical protein	K13126 PABPC; polyadenylate-binding protein 
E        SPRG_02675 hypothetical protein	K24983 G3BP2; Ras GTPase-activating protein-binding protein 2 
E        SPRG_08669 hypothetical protein	K15026 EIF2A; translation initiation factor 2A 
E        SPRG_00125 hypothetical protein	K03253 EIF3B; translation initiation factor 3 subunit B 
E        SPRG_00922 ATP-dependent RNA helicase eIF4A	K03257 EIF4A; translation initiation factor 4A 
E        SPRG_09992 eukaryotic initiation factor 4A-III	K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7] 
E        SPRG_13388 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        SPRG_20125 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        SPRG_20698 hypothetical protein	K03260 EIF4G; translation initiation factor 4G 
E        SPRG_14266 CAMK protein kinase	K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
E        SPRG_19716 CAMK/CAMKL protein kinase	K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
E        SPRG_15030 guanine nucleotide-binding protein subunit beta-2-like 1	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        SPRG_20942 guanine nucleotide-binding protein subunit beta-2-like 1	K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
E        SPRG_20878 hypothetical protein	K18763 LARP4; la-related protein 4 
B  mRNA degradation factors
C    5'-3' decay
D      Decapping complex
E        SPRG_03036 hypothetical protein	K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-] 
E        SPRG_06340 DEAD-box ATP-dependent RNA helicase 8	K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7] 
D      Lsm complex
E        SPRG_19997 hypothetical protein	K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1 
E        SPRG_02015 U6 snRNA-associated Sm-like protein LSm2	K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2 
E        SPRG_10785 U6 snRNA-associated Sm-like protein LSm3	K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3 
E        SPRG_13150 hypothetical protein	K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4 
E        SPRG_04072 hypothetical protein	K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5 
E        SPRG_02970 U6 snRNA-associated Sm-like protein LSm6	K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6 
E        SPRG_15839 hypothetical protein	K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7 
E        SPRG_11298 hypothetical protein	K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8 
D      5' exonucleases
E        SPRG_14369 hypothetical protein	K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-] 
D      Other 5'-3' decay factors
E        SPRG_07731 hypothetical protein	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
C    3'-5' decay
D      Core exosome factors
E        SPRG_11851 hypothetical protein	K03679 RRP4; exosome complex component RRP4 
E        SPRG_14348 hypothetical protein	K03681 RRP40; exosome complex component RRP40 
E        SPRG_10204 hypothetical protein	K11600 RRP41; exosome complex component RRP41 
E        SPRG_04585 hypothetical protein	K12590 RRP46; exosome complex component RRP46 
E        SPRG_10840 hypothetical protein	K12587 MTR3; exosome complex component MTR3 
E        SPRG_10275 hypothetical protein	K12589 RRP42; exosome complex component RRP42 
E        SPRG_03161 hypothetical protein	K12586 RRP43; exosome complex component RRP43 
E        SPRG_02283 hypothetical protein	K03678 RRP45; exosome complex component RRP45 
D      Exosome cofactors
E        SPRG_19128 hypothetical protein	K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-] 
E        SPRG_00642 hypothetical protein	K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-] 
E        SPRG_00121 hypothetical protein	K12592 C1D; exosome complex protein LRP1 
E        SPRG_07309 hypothetical protein	K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type 
E        SPRG_01312 hypothetical protein	K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7] 
D      TRAMP complex
E        SPRG_00867 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        SPRG_02003 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        SPRG_02834 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        SPRG_03509 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        SPRG_04479 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        SPRG_10005 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        SPRG_13382 hypothetical protein	K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] 
E        SPRG_14450 hypothetical protein	K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6] 
D      Ski complex
E        SPRG_06913 hypothetical protein	K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6] 
E        SPRG_14077 hypothetical protein	K12600 SKI3; superkiller protein 3 
D      Ccr4-NOT complex
E        SPRG_12545 hypothetical protein	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        SPRG_12941 hypothetical protein	K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] 
E        SPRG_06770 hypothetical protein	K12604 CNOT1; CCR4-NOT transcription complex subunit 1 
E        SPRG_05301 hypothetical protein	K12605 CNOT2; CCR4-NOT transcription complex subunit 2 
E        SPRG_14773 hypothetical protein	K12580 CNOT3; CCR4-NOT transcription complex subunit 3 
E        SPRG_05320 hypothetical protein	K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27] 
E        SPRG_00768 hypothetical protein	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        SPRG_16793 hypothetical protein	K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8 
E        SPRG_10235 cell differentiation protein RCD1	K12606 RCD1; CCR4-NOT transcription complex subunit 9 
E        SPRG_02674 hypothetical protein	K12607 CNOT10; CCR4-NOT transcription complex subunit 10 
E        SPRG_09357 hypothetical protein	K12608 CAF16; CCR4-NOT complex subunit CAF16 
D      Pan complex
E        SPRG_00453 hypothetical protein	K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4] 
E        SPRG_11569 hypothetical protein	K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3 
D      Other 3'-5' decay factors
E        SPRG_10440 hypothetical protein	K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4] 
E        SPRG_06558 hypothetical protein	K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6] 
E        SPRG_11328 hypothetical protein	K18764 NOCT; nocturnin [EC:3.1.3.108] 
E        SPRG_19107 hypothetical protein	K18764 NOCT; nocturnin [EC:3.1.3.108] 
E        SPRG_07731 hypothetical protein	K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59] 
E        SPRG_04158 hypothetical protein	K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-] 
C    Other degradation factors
D      RNases
#
A<b>Prokaryotic type</b>
B  Bacterial mRNA degradation factors
C    RNA degradosome components
D      Ribonucreases
E        SPRG_06952 hypothetical protein	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
E        SPRG_16260 hypothetical protein	K03685 rnc; ribonuclease III [EC:3.1.26.3] 
D      Helicases
D      Other RNA degradosome components
E        SPRG_02328 enolase 2	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        SPRG_02908 enolase	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        SPRG_13723 hypothetical protein	K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11] 
E        SPRG_06133 polyribonucleotide nucleotidyltransferase	K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 
E        SPRG_06576 hypothetical protein	K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11] 
C    Other RNA degradation factors
D      Chaperones
E        SPRG_02294 chaperone dnaK	K04043 dnaK; molecular chaperone DnaK 
E        SPRG_02918 chaperonin GroL	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
D      Others
D      Bacterial Small RNA Regulators
B  Archeal mRNA degradation factors
C    Exosome components
D      Core exosome
E        SPRG_11851 hypothetical protein	K03679 RRP4; exosome complex component RRP4 
D      Cofactors
E        SPRG_10204 hypothetical protein	K11600 RRP41; exosome complex component RRP41 
E        SPRG_10275 hypothetical protein	K12589 RRP42; exosome complex component RRP42 
D      Others
!
#<hr>
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#Last updated: August 27, 2025