+F Repair protein KO
#
DNA Repair and Recombination Proteins - Saprolegnia parasitica
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPRG_02841 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SPRG_05048 hypothetical protein K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D SPRG_03798 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SPRG_03806 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPRG_01482 hypothetical protein K20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]
E SPRG_10979 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPRG_05894 hypothetical protein K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
E SPRG_01561 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E SPRG_03038 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SPRG_10327 hypothetical protein K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
E SPRG_02459 hypothetical protein K10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F SPRG_06266 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F SPRG_21311 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
F SPRG_21507 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
F SPRG_04041 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F SPRG_04353 hypothetical protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F SPRG_09753 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F SPRG_18408 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F SPRG_01401 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
E SPRG_01445 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E SPRG_04596 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D Short Patch-BER factors
E SPRG_19502 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other BER factors
E SPRG_19221 hypothetical protein K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E SPRG_06657 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E SPRG_11939 hypothetical protein K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E SPRG_07053 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E SPRG_04562 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E SPRG_03588 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
E SPRG_20730 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F SPRG_01780 hypothetical protein K10838 XPC; xeroderma pigmentosum group C-complementing protein
F SPRG_00615 UV excision repair protein Rad23 K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F SPRG_11654 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F SPRG_01614 hypothetical protein K10609 CUL4; cullin 4
F SPRG_04038 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
F SPRG_06800 hypothetical protein K15082 RAD7; DNA repair protein RAD7
F SPRG_20587 hypothetical protein K15083 RAD16; DNA repair protein RAD16
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F SPRG_08025 hypothetical protein K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F SPRG_07858 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F SPRG_05447 RNA polymerase Rpb3/Rpb11 dimeriZation domain-containing protein K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F SPRG_03275 hypothetical protein K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F SPRG_05117 hypothetical protein K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F SPRG_05777 hypothetical protein K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F SPRG_15027 hypothetical protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F SPRG_20943 hypothetical protein K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F SPRG_12350 hypothetical protein K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F SPRG_20734 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F SPRG_17154 hypothetical protein K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F SPRG_07688 DNA-directed RNA polymerase I K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F SPRG_01664 hypothetical protein K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F SPRG_01449 hypothetical protein K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F SPRG_11654 hypothetical protein K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F SPRG_01614 hypothetical protein K10609 CUL4; cullin 4
F SPRG_04038 hypothetical protein K10610 DDB1; DNA damage-binding protein 1
F SPRG_12152 hypothetical protein K10570 ERCC8; DNA excision repair protein ERCC-8
E Other TCR factor
F SPRG_05391 hypothetical protein K10841 ERCC6; DNA excision repair protein ERCC-6
F SPRG_04970 hypothetical protein K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E SPRG_11271 hypothetical protein K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E SPRG_05932 hypothetical protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E SPRG_09273 hypothetical protein K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E SPRG_09130 hypothetical protein K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E SPRG_05081 hypothetical protein K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E SPRG_04339 hypothetical protein K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E SPRG_16993 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E SPRG_04362 hypothetical protein K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E SPRG_11995 CMGC/CDK/CDK7 protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E SPRG_05845 CMGC/CDK protein kinase K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E SPRG_00391 hypothetical protein K06634 CCNH; cyclin H
E SPRG_01643 hypothetical protein K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E SPRG_10939 hypothetical protein K07466 RFA1; replication factor A1
E SPRG_10350 hypothetical protein K10739 RFA2; replication factor A2
E SPRG_04105 hypothetical protein K10740 RPA3; replication factor A3
D Other NER factors
E SPRG_05873 hypothetical protein K10847 XPA; DNA-repair protein complementing XP-A cells
E SPRG_03981 hypothetical protein K10849 ERCC1; DNA excision repair protein ERCC-1
E SPRG_05237 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E SPRG_08796 hypothetical protein K10846 ERCC5; DNA excision repair protein ERCC-5
E SPRG_05586 hypothetical protein K15075 MET18; DNA repair/transcription protein MET18/MMS19
E SPRG_08828 hypothetical protein K03869 CUL3; cullin 3
E SPRG_11463 hypothetical protein K03872 ELOC; elongin-C
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SPRG_01049 hypothetical protein K08735 MSH2; DNA mismatch repair protein MSH2
E SPRG_05442 hypothetical protein K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E SPRG_06322 hypothetical protein K08734 MLH1; DNA mismatch repair protein MLH1
E SPRG_04063 hypothetical protein K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E SPRG_06266 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E SPRG_21311 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
E SPRG_21507 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
E SPRG_04041 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E SPRG_10939 hypothetical protein K07466 RFA1; replication factor A1
E SPRG_10350 hypothetical protein K10739 RFA2; replication factor A2
E SPRG_04105 hypothetical protein K10740 RPA3; replication factor A3
D RFC (replication factor C)
E SPRG_11725 hypothetical protein K10754 RFC1; replication factor C subunit 1
E SPRG_21645 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E SPRG_11947 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
E SPRG_04625 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E SPRG_04997 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
E SPRG_07604 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E SPRG_01445 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E SPRG_05104 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E SPRG_03635 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E SPRG_08289 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E SPRG_06794 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E SPRG_10631 hypothetical protein K10867 NBN; nibrin
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
E SPRG_08149 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D BRCA1-C complex
E SPRG_06794 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
E SPRG_10631 hypothetical protein K10867 NBN; nibrin
D BRCA complex
E SPRG_21155 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E SPRG_12333 DNA repair protein RAD51 1 K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E SPRG_21155 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E SPRG_12333 DNA repair protein RAD51 1 K04482 RAD51; DNA repair protein RAD51
E SPRG_01520 hypothetical protein K10869 RAD51L1; RAD51-like protein 1
E SPRG_02496 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E SPRG_16405 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E SPRG_10550 hypothetical protein K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
E SPRG_10635 hypothetical protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
E SPRG_05299 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E SPRG_18051 hypothetical protein K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
D RecQ family DNA helicases
E SPRG_04659 hypothetical protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E SPRG_00320 hypothetical protein K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E SPRG_01798 hypothetical protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E SPRG_13157 hypothetical protein K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E SPRG_01798 hypothetical protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E SPRG_00629 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E SPRG_10359 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E SPRG_10939 hypothetical protein K07466 RFA1; replication factor A1
E SPRG_10350 hypothetical protein K10739 RFA2; replication factor A2
E SPRG_04105 hypothetical protein K10740 RPA3; replication factor A3
D Protein phosphatase 4
E SPRG_07040 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E SPRG_18895 hypothetical protein K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E SPRG_17318 hypothetical protein K17491 SMEK; protein phosphatase 4 regulatory subunit 3
E SPRG_10607 hypothetical protein K15426 PPP4R4; serine/threonine-protein phosphatase 4 regulatory subunit 4
D AP-5 complex
D SMC5-SMC6 complex
E SPRG_01116 hypothetical protein K22803 SMC5; structural maintenance of chromosomes protein 5
E SPRG_16032 hypothetical protein K22804 SMC6; structural maintenance of chromosomes protein 6
E SPRG_10380 hypothetical protein K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E SPRG_15225 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E SPRG_14099 hypothetical protein K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
E SPRG_04712 hypothetical protein K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E SPRG_18588 hypothetical protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E SPRG_08175 hypothetical protein K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E SPRG_19533 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E SPRG_04564 hypothetical protein K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E SPRG_14615 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E SPRG_08160 hypothetical protein K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E SPRG_14094 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E SPRG_07116 hypothetical protein K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E SPRG_07102 hypothetical protein K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
E SPRG_13186 hypothetical protein K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
E SPRG_03281 hypothetical protein K22685 WSS1; DNA-dependent metalloprotease WSS1 [EC:3.4.24.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E SPRG_19108 hypothetical protein K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E SPRG_10445 hypothetical protein K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E SPRG_12566 hypothetical protein K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E SPRG_06794 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D DNA Ligase 4 complex
E SPRG_10651 hypothetical protein K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
D X-family DNA polymerases
E SPRG_07053 hypothetical protein K03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
E SPRG_19502 hypothetical protein K02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]
D Other NHEJ factors
E SPRG_06657 hypothetical protein K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E SPRG_01070 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
E SPRG_16340 hypothetical protein K19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]
C FA (Fanconi anemia) pathway
D FA core complex
E SPRG_03565 hypothetical protein K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D FA core complex binding factors
E SPRG_08618 hypothetical protein K15360 STRA13; centromere protein X
E SPRG_09951 hypothetical protein K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
D Bloom's syndrome complex (BTR)
E SPRG_01798 hypothetical protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E SPRG_00629 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E SPRG_10359 hypothetical protein K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
E SPRG_08268 hypothetical protein K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E SPRG_08149 hypothetical protein K15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]
D Other FA pathway factors
E SPRG_20011 hypothetical protein K15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]
E SPRG_21155 hypothetical protein K04482 RAD51; DNA repair protein RAD51
E SPRG_12333 DNA repair protein RAD51 1 K04482 RAD51; DNA repair protein RAD51
E SPRG_02496 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E SPRG_16405 hypothetical protein K10870 RAD51L2; RAD51-like protein 2
E SPRG_06836 hypothetical protein K11137 TELO2; telomere length regulation protein
C Other DSBR factors
D Protein phosphatase 6
E SPRG_01488 phytochrome-associated serine/threonine protein phosphatase K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
D Ubiquitin ligases
E SPRG_20649 hypothetical protein K20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]
D Others
E SPRG_07126 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
E SPRG_01131 hypothetical protein K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SPRG_19302 hypothetical protein K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D SPRG_09244 hypothetical protein K03511 POLK; DNA polymerase kappa [EC:2.7.7.7]
D SPRG_12184 hypothetical protein K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D SPRG_01120 hypothetical protein K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D SPRG_03371 ubiquitin-conjugating enzyme E2 2 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D SPRG_00931 hypothetical protein K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D SPRG_02199 hypothetical protein K15505 RAD5; DNA repair protein RAD5 [EC:5.6.2.-]
D SPRG_00487 hypothetical protein K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D SPRG_01784 hypothetical protein K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D SPRG_01445 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
B Check point factors
C Rad9-Hus1-Rad1 complex
D SPRG_02075 hypothetical protein K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D SPRG_02867 hypothetical protein K10903 HUS1; HUS1 checkpoint protein
D SPRG_16457 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D SPRG_21645 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D SPRG_11947 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D SPRG_04625 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D SPRG_04997 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D SPRG_07604 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D SPRG_16457 hypothetical protein K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D SPRG_00933 hypothetical protein K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D SPRG_19172 hypothetical protein K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
C Triple T complex
D SPRG_06836 hypothetical protein K11137 TELO2; telomere length regulation protein
D SPRG_15694 hypothetical protein K20403 TTI1; TELO2-interacting protein 1
D SPRG_05558 hypothetical protein K23115 TTI2; TELO2-interacting protein 2
D SPRG_18347 hypothetical protein K23115 TTI2; TELO2-interacting protein 2
C BAG6-UBL4A-GET4 complex
D SPRG_09672 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D SPRG_05293 hypothetical protein K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D SPRG_22315 hypothetical protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D SPRG_09274 hypothetical protein K06630 YWHAE; 14-3-3 protein epsilon
D SPRG_03103 14-3-3-like protein K06630 YWHAE; 14-3-3 protein epsilon
D SPRG_08383 WEE protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D SPRG_01495 NEK/NEK1 protein kinase K08857 NEK1_4_5; serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
D SPRG_10874 hypothetical protein K12196 VPS4; vacuolar protein-sorting-associated protein 4
B Other factors with a suspected DNA repair function
C DNA polymerases
D SPRG_10906 hypothetical protein K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
D SPRG_22272 hypothetical protein K22761 PRIMPOL; DNA-directed primase/polymerase protein [EC:2.7.7.102 2.7.7.7]
C Nucleases
D SPRG_08518 hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D SPRG_18138 hypothetical protein K15340 DCLRE1A; DNA cross-link repair 1A protein
D SPRG_07516 hypothetical protein K21813 ENDOV; endonuclease V [EC:3.1.26.-]
C Helicases
D SPRG_01594 hypothetical protein K20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]
C PSO4 complex
D SPRG_13995 hypothetical protein K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D SPRG_05174 hypothetical protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D SPRG_06610 hypothetical protein K12861 BCAS2; pre-mRNA-splicing factor SPF27
D SPRG_02956 hypothetical protein K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D SPRG_03698 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPRG_02929 hypothetical protein K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D SPRG_02930 hypothetical protein K17816 NUDT1; 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]
D SPRG_01422 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SPRG_04116 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SPRG_02841 hypothetical protein K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SPRG_03798 hypothetical protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SPRG_03806 hypothetical protein K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E SPRG_10979 hypothetical protein K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SPRG_01561 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
E SPRG_03038 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
E SPRG_08136 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SPRG_08136 hypothetical protein K02335 polA; DNA polymerase I [EC:2.7.7.7]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D SPRG_03698 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SPRG_01422 hypothetical protein K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024