+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptomyces parvulus

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS E Spa2297_32540 hypothetical protein K15670 rifA; rifamycin polyketide synthase modules 1, 2 and 3 [EC:6.2.1.74] E Spa2297_32555 beta-ketoacyl synthase K15672 rifC_D; rifamycin polyketide synthase modules 7 and 8 E Spa2297_32560 polyketide synthase K15673 rifE; rifamycin polyketide synthase modules 9 and 10 D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E Spa2297_22465 beta-ACP synthase K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E Spa2297_22460 polyketide beta-ketoacyl synthase K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E Spa2297_22455 curamycin polyketide synthase K14669 whiEV; minimal PKS acyl carrier protein E Spa2297_22450 polyketide cyclase K14670 whiEVI; aromatase E Spa2297_22445 polyketide synthase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E Spa2297_32720 beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Spa2297_32725 beta-ketoacyl synthase K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Spa2297_32730 actinorhodin polyketide synthase K05553 actI3; minimal PKS acyl carrier protein E Spa2297_32765 ketoacyl reductase K12420 actIII; ketoreductase [EC:1.1.1.-] E Spa2297_32770 cyclase K05554 actVII; aromatase [EC:4.2.1.-] E Spa2297_32740 MBL fold metallo-hydrolase K05555 actIV; cyclase [EC:4.-.-.-] D Nonaketide PKS E Spa2297_32720 beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Spa2297_32725 beta-ketoacyl synthase K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Spa2297_32730 actinorhodin polyketide synthase K05553 actI3; minimal PKS acyl carrier protein E Spa2297_32765 ketoacyl reductase K12420 actIII; ketoreductase [EC:1.1.1.-] D Decaketide PKS E Spa2297_32720 beta-ACP synthase K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Spa2297_32725 beta-ketoacyl synthase K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Spa2297_32730 actinorhodin polyketide synthase K05553 actI3; minimal PKS acyl carrier protein E Spa2297_32765 ketoacyl reductase K12420 actIII; ketoreductase [EC:1.1.1.-] B Type III PKS C Plant type C Fungal type C Bacterial type D Spa2297_31515 polyketide synthase K16232 gcs; germicidin synthase D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D Spa2297_00520 protein mbtH K05375 mbtH; MbtH protein D Spa2297_32395 hypothetical protein K05375 mbtH; MbtH protein D Spa2297_32990 protein mbtH K05375 mbtH; MbtH protein D Spa2297_33095 protein mbtH K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D Spa2297_27735 4'-phosphopantetheinyl transferase K02362 entD; enterobactin synthetase component D / holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7] D Spa2297_32945 hypothetical protein K02364 entF; L-serine---[L-seryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.72] C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C Spa2297_32605 3-(3-hydroxyphenyl)propionate hydroxylase K16022 rif19; flavoprotein hydroxylase C Spa2297_01655 cytochrome K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C Spa2297_12320 cytochrome K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C Spa2297_09375 epoxide hydrolase K21159 sgcF; epoxide hydrolase C Spa2297_32735 hypothetical protein K14253 oxyE; 6-methylpretetramide 4-monooxygenase [EC:1.14.13.232] C Spa2297_32760 oxygenase K14252 oxyL; 6-methylpretetramide 4-monooxygenase / 4-hydroxy-6-methylpretetramide 12a-monooxygenase [EC:1.14.13.232 1.14.13.233] C Spa2297_22470 protein in whiE locus K14673 whiEII; putative monooxygenase C Spa2297_22480 polyketide hydroxylase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C Spa2297_01510 methyltransferase K14251 oxyF; C-methyltransferase [EC:2.1.1.-] B Glycosyltransferase B Halogenase C Spa2297_32570 tryptophan halogenase K16033 asm12; FADH2-dependent halogenase C Spa2297_32975 tryptophan halogenase K16431 cepH; FAD-dependent halogenase [EC:1.14.19.-] C Spa2297_04645 halogenase K14257 ctcP; tetracycline 7-halogenase / FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-] C Spa2297_32420 chemotaxis protein CheX K15650 cmaB; non-haem Fe2+, alpha-ketoglutarate-dependent halogenase B beta-Branched incorporating proteins B Others C Spa2297_32565 3-amino-5-hydroxybenzoic acid synthase K15466 rifF; amide synthase C Spa2297_21225 hypothetical protein K14628 actVI2; enoyl reductase # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase C Spa2297_02905 GntR family transcriptional regulator K16423 hpgT; (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103] C Spa2297_26655 GntR family transcriptional regulator K16423 hpgT; (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103] C Spa2297_33005 GntR family transcriptional regulator K16423 hpgT; (S)-3,5-dihydroxyphenylglycine transaminase [EC:2.6.1.103] B Others C Spa2297_02915 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C Spa2297_26610 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C Spa2297_32985 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C Spa2297_02910 alpha-hydroxy-acid oxidizing enzyme K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C Spa2297_26640 alpha-hydroxy-acid oxidizing enzyme K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C Spa2297_32980 alpha-hydroxy-acid oxidizing enzyme K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: June 19, 2024