+C Peptidases and inhibitors KO #

  Peptidases and Inhibitors - Serratia proteamaculans

% ! AAspartic peptidases B Family A1: pepsin family B Family A2: retropepsin family B Family A5: thermopsin family B Family A8: signal peptidase II family C Spro_0699 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36] B Family A22: presenilin family B Family A24: type IV prepilin peptidase family C Spro_4241 Prepilin peptidase K02464 gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-] B Family A25: gpr protease family B Family A26: omptin family B Family A28 B Family A31: HybD endopeptidase family C Spro_2426 hydrogenase maturation protease HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] B Family A36 # ACysteine peptidases B Family C1: papain family B Family C2: calpain family B Family C3: picornain family B Family C4: NIa protease family B Family C5 B Family C9 B Family C10: streptopain family B Family C11: clostripain family B Family C12: ubiquitin C-terminal hydrolase family B Family C13: legumain family B Family C14: caspase family B Family C15: pyroglutamyl peptidase I family C Spro_1260 pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] C Spro_2993 pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] B Family C16 B Family C19: ubiquitin-specific protease family B Family C25: gingipain family B Family C26: gamma-glutamyl hydrolase family C Spro_2565 glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C Spro_3595 GMP synthase, large subunit K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C Spro_4317 glutamine amidotransferase class-I K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C Spro_2067 peptidase C26 K09473 puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94] B Family C27 B Family C30 B Family C37 B Family C39 C Spro_2317 ABC transporter-related protein K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB B Family C40 C Spro_3244 NLP/P60 protein K13694 mepS; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13] C Spro_2197 NLP/P60 protein K19303 mepH; murein DD-endopeptidase [EC:3.4.-.-] C Spro_2161 NLP/P60 protein K13695 nlpC; probable lipoprotein NlpC B Family C44 C Spro_3328 amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C Spro_4344 Glutamate synthase (ferredoxin) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] C Spro_0011 glucosamine--fructose-6-phosphate aminotransferase, isomerizing K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C Spro_1222 asparagine synthase (glutamine-hydrolyzing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] B Family C45 B Family C46: hedgehog family B Family C47: staphopain family B Family C48: Ulp1 endopeptidase family B Family C50: separase family B Family C54: Aut2 peptidase family B Family C55: YopJ protease family B Family C56: PfpI endopeptidase family C Spro_2475 intracellular protease, PfpI family K05520 yhbO; deglycase [EC:3.5.1.124] C Spro_1082 DJ-1 family protein K03152 thiJ; protein deglycase [EC:3.5.1.124] B Family C57: vaccinia virus I7 peptidase family B Family C58 B Family C59 B Family C60 B Family C63 B Family C64 B Family C65 B Family C67 B Family C69 B Family C70 B Family C75 B Family C76 B Family C78 B Family C79 B Family C82 C Spro_0598 ErfK/YbiS/YcfS/YnhG family protein K19235 ybiS; L,D-transpeptidase YbiS C Spro_2185 ErfK/YbiS/YcfS/YnhG family protein K19236 ycfS; L,D-transpeptidase YcfS C Spro_1726 Peptidoglycan-binding domain 1 protein K21470 ycbB; L,D-transpeptidase YcbB B Family C83 B Family C85 B Family C86 B Family C88 B Family C89 B Family C97 B Family C98 B Family C110 # AGlutamic peptidases B Family G1 B Family G4 B Family G5: prenyl protease 2 family C Spro_1293 Abortive infection protein K07052 K07052; CAAX protease family protein # AMetallo peptidases B Family M1 C Spro_1734 aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] B Family M2 B Family M3 C Spro_4701 Oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70] C Spro_2306 Peptidyl-dipeptidase Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5] B Family M4: thermolysin family B Family M5: mycolysin family B Family M6: immune inhibitor A family B Family M7: snapalysin family B Family M8: leishmanolysin family B Family M9 B Family M10 C Spro_0210 Serralysin K01406 prtC; serralysin [EC:3.4.24.40] C Spro_2387 Serralysin K01406 prtC; serralysin [EC:3.4.24.40] B Family M12: astacin/adamalysin family B Family M13: neprilysin family B Family M14: carboxypeptidase A family B Family M15: zinc D-Ala-D-Ala carboxypeptidase family C Spro_2346 peptidase M15D vanX D-ala-D-ala dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] C Spro_3474 putative phagelysin K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-] C Spro_4929 hypothetical protein K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-] B Family M16: pitrilysin family C Spro_3815 peptidase M16 domain protein K01407 ptrA; protease III [EC:3.4.24.55] B Family M17: leucyl aminopeptidase family C Spro_0562 Leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] C Spro_2848 Leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] C Spro_3620 PepB aminopeptidase K07751 pepB; PepB aminopeptidase [EC:3.4.11.23] B Family M18 B Family M19: membrane dipeptidase family B Family M20 C Spro_3501 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C Spro_2009 peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] C Spro_3359 peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4] C Spro_0963 aminoacyl-histidine dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-] C Spro_3206 amidohydrolase K01451 hipO; hippurate hydrolase [EC:3.5.1.32] C Spro_4200 amidohydrolase K12940 abgA; aminobenzoyl-glutamate utilization protein A C Spro_4201 amidohydrolase K12941 abgB; aminobenzoyl-glutamate utilization protein B C Spro_0937 amidase, hydantoinase/carbamoylase family K02083 allC; allantoate deiminase [EC:3.5.3.9] B Family M23 C Spro_2772 peptidase M23B K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] B Family M24 C Spro_1365 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C Spro_3791 methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C Spro_0263 peptidase M24 K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9] C Spro_3919 peptidase M24 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] B Family M26 B Family M27 B Family M28: aminopeptidase Y family C Spro_0815 peptidase M28 K09612 iap; alkaline phosphatase isozyme conversion protein [EC:3.4.11.-] B Family M29: aminopeptidase T family B Family M32: carboxypeptidase Taq family C Spro_2592 Carboxypeptidase Taq K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19] B Family M34: anthrax lethal factor family B Family M35: deuterolysin family B Family M36: fungalysin family B Family M38: beta-aspartyl dipeptidase family B Family M41: FtsH endopeptidase family C Spro_0483 ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] B Family M42: glutamyl aminopeptidase family B Family M43: cytophagalysin family B Family M44 B Family M48: Ste24 endopeptidase family C Spro_2120 HtpX domain protein K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] C Spro_3955 peptidase M48 Ste24p K07387 K07387; metalloprotease [EC:3.4.24.-] C Spro_3517 peptidase M48 Ste24p K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-] B Family M49: dipeptidyl-peptidase III family B Family M50: S2P protease family C Spro_3783 putative membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] B Family M54 B Family M55: DppA aminopeptidase family B Family M56 B Family M67 B Family M72 B Family M73 B Family M74 C Spro_3373 peptidase U6 penicillin-insensitive murein endopeptidase K07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-] B Family M80 B Family M82 B Family M85 B Family M88 B Family M90 C Spro_3110 protein of unknown function DUF980 K09933 mtfA; MtfA peptidase B Family M98 # AAsparagine peptide lyases B Family N1 B Family N8 # AMixed peptidases B Family P1: DmpA aminopeptidase family B Family P2 # ASerine peptidases B Family S1: chymotrypsin family C Spro_2594 peptidase S1 and S6 chymotrypsin/Hap K04775 ydgD; protease YdgD [EC:3.4.21.-] C Spro_0789 protease Do K04771 degP; serine protease Do [EC:3.4.21.107] C Spro_4352 protease Do K04772 degQ; serine protease DegQ [EC:3.4.21.-] C Spro_4353 periplasmic serine protease DegS K04691 hhoB; serine protease DegS [EC:3.4.21.-] B Family S3: togavirin family B Family S6 B Family S7: flavivirin family B Family S8: subtilisin family B Family S9: prolyl oligopeptidase family C Spro_2232 Prolyl oligopeptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26] C Spro_1937 Oligopeptidase B K01354 ptrB; oligopeptidase B [EC:3.4.21.83] C Spro_3467 Oligopeptidase B K01354 ptrB; oligopeptidase B [EC:3.4.21.83] B Family S10 B Family S11: D-Ala-D-Ala carboxypeptidase A family C Spro_1198 Serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C Spro_1628 Serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C Spro_2636 Serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C Spro_1352 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-] C Spro_2561 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-] B Family S12: D-Ala-D-Ala carboxypeptidase B family C Spro_0636 beta-lactamase K18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase [EC:3.4.16.4 3.4.21.-] B Family S13: D-Ala-D-Ala peptidase C family C Spro_0479 D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] B Family S14: ClpP endopeptidase family C Spro_1095 ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C Spro_1978 Endopeptidase Clp K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] B Family S15 B Family S16: lon protease family C Spro_1097 ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] C Spro_1752 putative Lon protease K04770 lonH; Lon-like ATP-dependent protease [EC:3.4.21.-] B Family S21: assemblin family B Family S24: LexA family C Spro_4460 transcriptional repressor, LexA family K01356 lexA; repressor LexA [EC:3.4.21.88] C Spro_2605 peptidase S24 and S26 domain protein K03503 umuD; DNA polymerase V [EC:3.4.21.-] B Family S26: signal peptidase I family C Spro_3670 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] B Family S28 B Family S31 B Family S32 B Family S33 C Spro_1940 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] B Family S41: C-terminal processing peptidase family C Spro_2119 carboxyl-terminal protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] B Family S45 C Spro_3142 Penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11] B Family S49: protease IV family C Spro_2722 signal peptide peptidase SppA, 67K type K04773 sppA; protease IV [EC:3.4.21.-] C Spro_2659 Peptidase S49 domain protein K04774 sohB; serine protease SohB [EC:3.4.21.-] B Family S50 B Family S51 C Spro_0257 Dipeptidase E K05995 pepE; dipeptidase E [EC:3.4.13.21] B Family S53 B Family S54: Rhomboid family C Spro_4639 Rhomboid family protein K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105] B Family S55: SpoIVB peptidase family B Family S62 B Family S66 B Family S77: phage prohead processing peptidase family B Family S78 # AThreonine peptidases B Family T1: proteasome family C Spro_4792 20S proteasome A and B subunits K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] B Family T2 C Spro_1549 peptidase T2 asparaginase 2 K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] B Family T3: gamma-glutamyltransferase family C Spro_1057 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] C Spro_2484 gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] C Spro_0930 Gamma-glutamyltransferase K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126] # APeptidases of unknown catalytic type B Family U32 C Spro_3561 peptidase U32 K08303 prtC; U32 family peptidase [EC:3.4.-.-] C Spro_0503 peptidase U32 K24845 ubiV; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiV [EC:1.97.1.15] C Spro_0504 peptidase U32 K24844 ubiU; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiU [EC:1.97.1.15] B Family U62 C Spro_4384 peptidase U62 modulator of DNA gyrase K03592 pmbA; PmbA protein C Spro_4404 peptidase U62 modulator of DNA gyrase K03568 tldD; TldD protein # APeptidase inhibitors B Family I1: Kazal family B Family I2: Kunitz - BPTI family B Family I4: serpin family B Family I11: ecotin family C Spro_1637 proteinase inhibitor I11 ecotin K08276 eco; ecotin B Family I17: WAP-type family B Family I25: cystatin family B Family I27: calpastatin family B Family I32: IAP family B Family I34: IA3 family B Family I35: timp family B Family I39: alpha2M family C Spro_3615 alpha-2-macroglobulin domain protein K06894 yfhM; alpha-2-macroglobulin B Family I47: latexin family B Family I49: proSAAS family B Family I51: IC family B Family I57: staphostatin B family B Family I63 B Family I80 B Family I87 C Spro_0434 HflC protein K04087 hflC; modulator of FtsH protease HflC C Spro_0433 HflK protein K04088 hflK; modulator of FtsH protease HflK B Family I93 ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 20, 2025 #
Classification taken and modified from MEROPS