+D Messenger RNA Biogenesis KO
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Prokaryotic Defense System - Serratia proteamaculans
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ACRISPR-Cas system
B Universal Cas proteins
B Type I CRISPR-Cas system
C Type I signiture cas proteins
C Subtype I-A factors
C Subtype I-B factors
C Subtype I-C factors
C Subtype I-D factors
C Subtype I-E factors
C Subtype I-F factors
C Subtype I-U factors
B Type II CRISPR-Cas system
C Type II signiture cas proteins
C Subtype II-A factors
C Subtype II-B factors
B Type III CRISPR-Cas system
C Type III signiture cas proteins
C Subtype III-A factors
C Subtype III-B factors
C Subtype III-U factors
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ARestriction and modification system (R-M system)
B Type I R-M system
C Spro_4084 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C Spro_4083 restriction modification system DNA specificity domain K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C Spro_4082 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
B Type II R-M system
C Restriction endonucleases
C DNA methyltransferases
D Spro_4602 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Spro_0573 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
B Type III R-M system
B Type IV R-M system
C Spro_0325 restriction endonuclease K07448 mrr; restriction system protein
C Spro_4097 restriction endonuclease K07448 mrr; restriction system protein
C Spro_4180 restriction endonuclease K07448 mrr; restriction system protein
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AToxin-antitoxin system (TA system)
B Type I TA system
C Hok-Sok
D Spro_3274 Hok/gef cell toxic protein K18920 hokA; protein HokA
D Spro_0947 Hok/gef cell toxic protein K18919 hokC_D; protein HokC/D
D Spro_0948 Hok/gef cell toxic protein K18919 hokC_D; protein HokC/D
D Spro_3975 Hok/gef cell toxic protein K18919 hokC_D; protein HokC/D
C SymE-SymR
C Ldr-Rdl
C TisB-IstR
C Ibs-Sib
C ShoB-OhsC
C RalR-RalA
B Type II TA system
C MazF-MazE
C ChpB-ChpS
C YhaV-PrlF
C RelE/StbE-RelB/StbD
D Spro_0055 transcriptional regulator, CopG family K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
D Spro_1651 prevent-host-death protein K18923 stbD; antitoxin StbD
C YafQ-dinJ
D Spro_3527 hypothetical protein K07473 dinJ; DNA-damage-inducible protein J
C YoeB-YefM
C HipA-HipB
D Spro_3691 HipA domain protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
D Spro_4311 HipA domain protein K07154 hipA; serine/threonine-protein kinase HipA [EC:2.7.11.1]
D Spro_0567 transcriptional regulator, XRE family K15773 hipB; HTH-type transcriptional regulator / antitoxin HipB
C HicA-HicB
D Spro_3400 conserved hypothetical protein K18843 hicB; antitoxin HicB
C YafO-YafN
C PspC-PspB
D Spro_2622 phage shock protein C, PspC K03973 pspC; phage shock protein C
D Spro_2623 shock B family protein K03970 pspB; phage shock protein B
C CcdB-CcdA
D Spro_1555 CcdB protein K19163 ccdB; toxin CcdB
D Spro_1554 Post-segregation antitoxin CcdA K19164 ccdA; antitoxin CcdA
C ParE-ParD
D Spro_0056 plasmid stabilization system K19092 parE1_3_4; toxin ParE1/3/4
D Spro_4209 putative addiction module antidote protein, CopG/Arc/MetJ family K07746 parD1_3_4; antitoxin ParD1/3/4
C Doc-Phd
C HigB-HigA
D Spro_4950 conserved hypothetical protein K19166 higB; mRNA interferase HigB [EC:3.1.-.-]
D Spro_4313 plasmid maintenance system killer K07334 higB-1; toxin HigB-1
D Spro_0317 protein of unknown function DUF955 K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D Spro_4949 helix-turn-helix domain protein K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D Spro_4314 plasmid maintenance system antidote protein, XRE family K21498 higA-1; antitoxin HigA-1
C MqsR-MqsA
C VapC-VapB
D Spro_3558 PilT protein domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D Spro_3559 SpoVT/AbrB domain protein K18829 mvpT; antitoxin VapB
D Spro_1038 PilT protein domain protein K28279 vapC22; ribonuclease VapC22 [EC:3.1.-.-]
D Spro_1037 prevent-host-death family protein K28280 vapB22; antitoxin VapB22
C PezT-PezA
C YobL-YobK
C YokI-YokJ
C YqcG-YqcF
C YxiD-YxxD
C FitB-FitA
D Spro_4619 PilT protein domain protein K07062 fitB; toxin FitB [EC:3.1.-.-]
D Spro_4618 conserved hypothetical protein K21495 fitA; antitoxin FitA
C BC_0920-BC_0921
C SpoIISA-SpoIISB
C Tse6-Tsi6
D Spro_3017 PAAR repeat-containing protein K28299 tse6; NAD(P)(+) glycohydrolase toxin Tse6 [EC:3.2.2.5]
C Type II TA system related factors
D Spro_1893 conserved hypothetical protein K12148 bssS; biofilm regulator BssS
D Spro_1392 protein of unknown function DUF1471 K12151 bhsA; multiple stress resistance protein BhsA
D Spro_1393 protein of unknown function DUF1471 K12151 bhsA; multiple stress resistance protein BhsA
D Spro_0766 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Spro_4411 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins
D Spro_4259 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D Spro_4263 DNA topoisomerase IV, B subunit K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D Spro_3417 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
B Type III TA system
C AbiQ system
B Type IV TA system
C YeeV-YeeU
D Spro_0396 conserved hypothetical protein K18837 cbtA; cytoskeleton-binding toxin CbtA and related proteins
D Spro_1770 protein of unknown function DUF1219 K18837 cbtA; cytoskeleton-binding toxin CbtA and related proteins
D Spro_4057 conserved hypothetical protein K18837 cbtA; cytoskeleton-binding toxin CbtA and related proteins
D Spro_4122 conserved hypothetical protein K18837 cbtA; cytoskeleton-binding toxin CbtA and related proteins
D Spro_1771 YagBYeeUYfjZ family protein K18838 cbeA; cytoskeleton bundling-enhancing protein CbeA and related proteins
C CptA-CptB
D Spro_3897 protein of unknown function DUF1434 K19168 cptA; toxin CptA
D Spro_3898 protein of unknown function DUF339 K09159 cptB; antitoxin CptB
C AbiEii-AbiEi
B Type V TA system
C GhoT-GhoS
C Other GhoT/OrtT toxin family protein
D Spro_2735 conserved hypothetical protein K28274 ortT; orphan toxin OrtT
B Type VI TA system
C SocB-SocA
B Type VII TA system
C Hha-TomB
D Spro_1118 Haemolysin expression modulating family protein K05839 hha; haemolysin expression modulating protein
D Spro_1119 conserved hypothetical protein K19162 tomB; hha toxicity modulator TomB
C TglT-TakA
C HepT-MntA
B Type VIII TA system
C SdsR-RyeA
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ADNA phosphothiolation system
B Sulfur modification proteins
C Spro_3627 cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
B DNA phosphorothioation-dependent restriction proteins
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 19, 2025