+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptomyces platensis

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS E CP981_04550 type I polyketide synthase K16384 amphC; polyene macrolide polyketide synthase D Pimaricinolide synthase D Candicidin PKS E CP981_04565 SDR family NAD(P)-dependent oxidoreductase K20787 fscC; candicidin polyketide synthase FscC D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E CP981_00305 hypothetical protein K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E CP981_04100 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K14667 whiEIII; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.-] E CP981_04095 ketosynthase chain-length factor K14668 whiEIV; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.-] E CP981_04090 acyl carrier protein K14669 whiEV; minimal PKS acyl carrier protein E CP981_04085 polyketide cyclase K14670 whiEVI; aromatase E CP981_04080 TcmI family type II polyketide cyclase K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E CP981_11520 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_34530 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_11515 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_34525 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_11510 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E CP981_34520 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E CP981_11570 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] E CP981_34485 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] E CP981_11560 cyclase K05554 actVII; aromatase [EC:4.2.1.-] E CP981_08290 MBL fold metallo-hydrolase K05555 actIV; cyclase [EC:4.-.-.-] D Nonaketide PKS E CP981_11520 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_34530 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_11515 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_34525 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_11510 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E CP981_34520 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E CP981_11570 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] E CP981_34485 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] E CP981_34465 cyclase family protein K14250 oxyN; cyclase D Decaketide PKS E CP981_11520 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_34530 beta-ketoacyl-[acyl-carrier-protein] synthase family protein K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_11515 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_34525 ketosynthase chain-length factor K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E CP981_11510 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E CP981_34520 acyl carrier protein K05553 actI3; minimal PKS acyl carrier protein E CP981_11570 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] E CP981_34485 SDR family NAD(P)-dependent oxidoreductase K12420 actIII; ketoreductase [EC:1.1.1.-] E CP981_34465 cyclase family protein K14250 oxyN; cyclase B Type III PKS C Plant type C Fungal type C Bacterial type D CP981_02965 type III polyketide synthase K19580 rppA; 1,3,6,8-tetrahydroxynaphthalene synthase [EC:2.3.1.233] D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D CP981_01750 MbtH family protein K05375 mbtH; MbtH protein D CP981_21720 MbtH family protein K05375 mbtH; MbtH protein D CP981_33510 MbtH family protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase C Bacillibactin synthetase C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase C Myxochelin synthetase C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C CP981_12975 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C CP981_07580 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CP981_34510 FAD-binding monooxygenase K14253 oxyE; 6-methylpretetramide 4-monooxygenase [EC:1.14.13.232] C CP981_34475 oxygenase K14252 oxyL; 6-methylpretetramide 4-monooxygenase / 4-hydroxy-6-methylpretetramide 12a-monooxygenase [EC:1.14.13.232 1.14.13.233] C CP981_34445 hypothetical protein K14256 oxyS; anhydrotetracycline 6-monooxygenase / 5a,11a-dehydrotetracycline 5-monooxygenase [EC:1.14.13.38 1.14.13.234] C CP981_04105 cupin domain-containing protein K14673 whiEII; putative monooxygenase C CP981_04115 monooxygenase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C CP981_04075 methyltransferase K14251 oxyF; C-methyltransferase [EC:2.1.1.-] C CP981_34505 methyltransferase K14251 oxyF; C-methyltransferase [EC:2.1.1.-] C CP981_34440 methyltransferase K14255 oxyT; 4-amino-anhydrotetracycline N4-methyltransferase [EC:2.1.1.335] B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C CP981_11565 nuclear transport factor 2 family protein K14626 actVIA; actinorhodin biosynthesis protein ActVIA C CP981_11505 flavin reductase K14631 actVB; flavin reductase ActVB [EC:1.5.1.-] C CP981_35180 flavin reductase K14631 actVB; flavin reductase ActVB [EC:1.5.1.-] C CP981_34455 dapC; succinyldiaminopimelate transaminase K14254 oxyQ; aminotransferase C CP981_34450 PPOX class F420-dependent oxidoreductase K21301 oxyR; 5a,11a-dehydrotetracycline reductase [EC:1.3.98.4] C CP981_13855 flavin reductase K21297 ctcQ; flavin reductase (NADH) [EC:1.5.1.36] C CP981_21750 flavin reductase K21297 ctcQ; flavin reductase (NADH) [EC:1.5.1.36] C CP981_34515 asnB; asparagine synthase (glutamine-hydrolyzing) K14244 oxyD; amidotransferase [EC:6.3.5.-] # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase C CP981_09155 glycosyltransferase K16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310] C CP981_33240 glycosyltransferase K16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310] B Aminotransferase B Others C CP981_21650 aspartate/glutamate racemase family protein K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024