+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Sphingomonas sp. NIBR02145</h2>
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A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    O3305_13650 murA; (GenBank) UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    O3305_07775 murB; (GenBank) UDP-N-acetylmuramate dehydrogenase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    O3305_07780 murC; (GenBank) UDP-N-acetylmuramate--L-alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    O3305_20975 Mur ligase family protein	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    O3305_07795 murD; (GenBank) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    O3305_07810 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase	K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] 
C    O3305_07765 D-alanine--D-alanine ligase	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
B  Racemase
C    O3305_12835 alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    O3305_18785 murI; (GenBank) glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
C    O3305_20970 LD-carboxypeptidase	K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13] 
B  Glycosyltransferase
C    O3305_07800 mraY; (GenBank) phospho-N-acetylmuramoyl-pentapeptide-transferase	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    O3305_07785 murG; (GenBank) undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
C    O3305_16130 undecaprenyl-diphosphate phosphatase	K06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27] 
B  Flippase
C    O3305_00025 murJ; (GenBank) murein biosynthesis integral membrane protein MurJ	K03980 murJ; putative peptidoglycan lipid II flippase 
C    O3305_22985 lipid II flippase MurJ	K03980 murJ; putative peptidoglycan lipid II flippase 
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A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    O3305_15450 PBP1A family penicillin-binding protein	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
C    O3305_17210 transglycosylase domain-containing protein	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
C    O3305_16305 pbpC; (GenBank) penicillin-binding protein 1C	K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] 
B  DD-Transpeptidase (Class B PBP)
C    O3305_02810 mrdA; (GenBank) penicillin-binding protein 2	K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] 
C    O3305_07815 penicillin-binding protein 2	K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    O3305_05095 D-alanyl-D-alanine carboxypeptidase family protein	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
C    O3305_09630 dacB; (GenBank) D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] 
B  Glycosyltransferase
C    O3305_01690 mtgA; (GenBank) monofunctional biosynthetic peptidoglycan transglycosylase	K03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28] 
C    O3305_07790 putative peptidoglycan glycosyltransferase FtsW	K03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28] 
C    O3305_02805 rodA; (GenBank) rod shape-determining protein RodA	K05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28] 
B  Transpeptidase
B  Carboxypeptidase
C    O3305_21770 M15 family metallopeptidase	K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] 
B  Endopeptidase
C    O3305_04085 M23 family metallopeptidase	K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] 
B  Sortase
B  Lytic transglycosylase
C    O3305_03130 transglycosylase SLT domain-containing protein	K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
C    O3305_00040 murein transglycosylase A	K08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29] 
C    O3305_05105 lytic murein transglycosylase	K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] 
C    O3305_02905 mltG; (GenBank) endolytic transglycosylase MltG	K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] 
C    O3305_05100 SPOR domain-containing protein	K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
C    O3305_17365 septal ring lytic transglycosylase RlpA family protein	K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
B  Amidase
C    O3305_17215 N-acetylmuramoyl-L-alanine amidase	K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
C    O3305_01775 N-acetylmuramoyl-L-alanine amidase	K11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
B  Structural protein
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#Last updated: May 15, 2025