+F Repair protein KO
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DNA Repair and Recombination Proteins - Pseudosulfitobacter pseudonitzschiae
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SULPSESMR1_02218 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SULPSESMR1_01441 phrA; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SULPSESMR1_02991 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SULPSESMR1_03464 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SULPSESMR1_03110 nudG; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_03166 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_02854 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_02398 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_00062 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SULPSESMR1_02218 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D SULPSESMR1_03466 ada; bifunctional transcriptional activator/DNA repair enzyme Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D SULPSESMR1_01441 phrA; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SULPSESMR1_00078 phrB; (6-4) photolyase K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D SULPSESMR1_03101 alkB; alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E SULPSESMR1_02433 uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E SULPSESMR1_02481 uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E SULPSESMR1_01743 alkA; putative bifunctional transcriptional activator/DNA repair enzyme AlkA K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E SULPSESMR1_02991 mutY; adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SULPSESMR1_02435 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E SULPSESMR1_03236 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E SULPSESMR1_03464 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SULPSESMR1_01270 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E SULPSESMR1_02962 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E SULPSESMR1_02026 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SULPSESMR1_01674 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SULPSESMR1_03312 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SULPSESMR1_01122 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E SULPSESMR1_00118 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E SULPSESMR1_02497 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E SULPSESMR1_01958 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SULPSESMR1_03312 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SULPSESMR1_01674 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SULPSESMR1_02624 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SULPSESMR1_02623 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SULPSESMR1_02583 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F SULPSESMR1_02674 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SULPSESMR1_01616 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SULPSESMR1_03176 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E SULPSESMR1_02896 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E SULPSESMR1_00837 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SULPSESMR1_03029 xseB; exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SULPSESMR1_00319 dnaE1; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SULPSESMR1_03232 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SULPSESMR1_01325 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E SULPSESMR1_02972 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SULPSESMR1_00884 dnaX; DNA polymerase III subunit tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SULPSESMR1_03192 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SULPSESMR1_02778 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SULPSESMR1_01674 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SULPSESMR1_01958 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SULPSESMR1_03674 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SULPSESMR1_01720 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SULPSESMR1_03792 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E SULPSESMR1_04449 vsr; very short patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SULPSESMR1_01580 recA; DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E SULPSESMR1_02206 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SULPSESMR1_02205 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SULPSESMR1_02207 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SULPSESMR1_02213 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SULPSESMR1_04607 sbcC; nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E SULPSESMR1_04606 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SULPSESMR1_01580 recA; DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
E SULPSESMR1_01820 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E SULPSESMR1_03231 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E SULPSESMR1_01673 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SULPSESMR1_03760 MloB K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SULPSESMR1_04578 MloB K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SULPSESMR1_02026 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SULPSESMR1_02664 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E SULPSESMR1_02780 recR; recombination protein RecR K06187 recR; recombination protein RecR
E SULPSESMR1_01930 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E SULPSESMR1_02206 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E SULPSESMR1_02205 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SULPSESMR1_02207 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E SULPSESMR1_03207 addA; ATP-dependent helicase/nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E SULPSESMR1_03208 PD-(D/E)XK nuclease superfamily protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E SULPSESMR1_04607 sbcC; nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E SULPSESMR1_04606 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E SULPSESMR1_01551 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SULPSESMR1_01597 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SULPSESMR1_03229 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SULPSESMR1_02170 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SULPSESMR1_03044 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SULPSESMR1_02026 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SULPSESMR1_02664 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F SULPSESMR1_02780 recR; recombination protein RecR K06187 recR; recombination protein RecR
F SULPSESMR1_01674 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SULPSESMR1_01282 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F SULPSESMR1_02284 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F SULPSESMR1_03299 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SULPSESMR1_01122 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F SULPSESMR1_00118 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
F SULPSESMR1_03675 hvrA; trans-acting regulatory protein HvrA K03746 hns; DNA-binding protein H-NS
F SULPSESMR1_00406 hvrA; trans-acting regulatory protein HvrA K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SULPSESMR1_02855 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D SULPSESMR1_01580 recA; DNA recombination/repair protein RecA K03553 recA; recombination protein RecA
D SULPSESMR1_01783 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SULPSESMR1_01930 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D SULPSESMR1_04051 damage-inducible protein K14160 imuA; protein ImuA
D SULPSESMR1_04050 DNA polymerase IV K14161 imuB; protein ImuB
D SULPSESMR1_04049 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D SULPSESMR1_03674 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SULPSESMR1_01720 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D SULPSESMR1_03792 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D SULPSESMR1_02188 recQ; ATP-dependent DNA helicase RecQ K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D SULPSESMR1_04065 putative ATP-dependent helicase Lhr K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D SULPSESMR1_03110 nudG; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_03166 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_02854 NUDIX domain protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_02398 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SULPSESMR1_00062 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SULPSESMR1_00326 nrdZ; vitamin B12-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SULPSESMR1_01764 nrdJ; vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SULPSESMR1_04909 nrdE2; ribonucleoside-diphosphate reductase subunit alpha 2 K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SULPSESMR1_04910 nrdF2; ribonucleoside-diphosphate reductase subunit beta nrdF2 K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024