+D
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Transporters - Streptococcus pyogenes M1 GAS (serotype M1)
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AABC transporters, eukaryotic type
B ABCA (ABC1) subfamily
C ABCA1, 2, 3, 4, 7, 12, 13 subgroups
C ABCA5, 6, 8, 9, 10 subgroups
B ABCB (MDR/TAP) subfamily
C ABCB2, 3, 8, 9, 10 subgroups
C ABCB1, 4, 5 subgroups
C ABCB6, 7 subgroups
C ABCB11 subgroup
C ABCB-BAC subgroup
D SPy_0229 putative ABC transporter, ATP-binding protein K18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SPy_0230 putative ABC transporter (ATP-binding protein) K18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump
D SPy_1148 putative ABC transporter (ATP-binding protein) K18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump
D SPy_1149 putative ABC transporter (ATP-binding protein) K18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump
B ABCC (CFTR/MRP) subfamily
C ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
C ABCC7 subgroup
C ABCC8, 9 subgroups
C ABCC-BAC subgroup
D SPy_1790 putative ABC transporter (ATP-binding protein) K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
D SPy_1791 putative ABC transporter (ATP-binding protein) K06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial
B ABCD (ALD) subfamily
C ABCD1 subgroup
C ABCD2 subgroup
C ABCD3 subgroup
C ABCD4 subgroup
C Others
B ABCG (White) subfamily
C ABCG1, 4 subgroups
C ABCG2, 3 subgroups
C ABCG5, 8 subgroups
B Other subfamilies
C Macrolide exporter
C Other ABC transporters
D SPy_0867 putative ABC transporter (ATP-binding protein) K15738 uup; ABC transport system ATP-binding/permease protein
D SPy_1084 srtT; ABC transporter (ATP binding) - lantibiotic associated K02021 ABC.MR; putative ABC transport system ATP-binding protein
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AABC transporters, prokaryotic type
B Mineral and organic ion transporters
C Sulfate/thiosulfate transporter
C Molybdate transporter
C Molybdate/tungstate transporter
C Tungstate transporter
C Nitrate/nitrite transporter
C Bicarbonate transporter
C Taurine transporter
C Sulfonate transporter
C Phthalate transporter
C Iron(III) transporter
D SPy_1063 putative periplasmic-iron-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
C Thiamine transporter
C Spermidine/putrescine transporter
D SPy_1105 potD; putative spermidine/putrescine ABC transporter (periplasmic transport protein) K11069 potD; spermidine/putrescine transport system substrate-binding protein
D SPy_1104 potC; putative spermidine/putrescine ABC transporter (permease protein) K11070 potC; spermidine/putrescine transport system permease protein
D SPy_1103 potB; putative spermidine / putrescine ABC transporter (permease protein) K11071 potB; spermidine/putrescine transport system permease protein
D SPy_1102 potA; putative spermidine / putrescine ABC transporter (ATP-binding protein) K11072 potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11]
C Putrescine transporter
C Putative spermidine/putrescine transporter
C Mannopine transporter
C 2-Aminoethylphosphonate transporter
C Glycine betaine/proline transporter
D SPy_0184 opuABC; putative glycine-betaine binding permease protein K02001 proW; glycine betaine/proline transport system permease protein
D SPy_0183 opuAA; putative glycine betaine/proline ABC transporter (ATP-binding protein) K02000 proV; glycine betaine/proline transport system ATP-binding protein [EC:7.6.2.9]
C Osmoprotectant transporter
D SPy_1134 putative ABC transporter (binding protein) K05845 opuC; osmoprotectant transport system substrate-binding protein
D SPy_1133 putative ABC transporter (ATP-binding protein) K05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]
C Riboflavin transporter
C Putative hydroxymethylpyrimidine transporter
C Putative thiamine transporter
C Putative thiamine transporter
C NitT/TauT family transporter
B Saccharide, polyol, and lipid transporters
C Maltose/maltodextrin transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Maltose transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Arabinogalactan oligomer/maltooligosaccharide transport system
D SPy_1306 malX; maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D SPy_1294 putative maltose/maltodextrin-binding protein K15770 cycB; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein
D SPy_1295 malF; putative maltose/maltodextrin ABC transport system (permease) K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SPy_1301 malC; maltodextrin transport system permease K15771 ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SPy_1296 malG; putative maltose/maltodextrin ABC transport system (permease) K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SPy_1299 malD; putative maltodextrin transport system permease K15772 ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Raffinose/stachyose/melibiose transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Alpha-glucoside transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Glucose/arabinose transporter
C Glucose/mannose transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Trehalose/maltose transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Trehalose transporter
C N-Acetylglucosamine transporter
C Cellobiose transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C N,N'-Diacetylchitobiose transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Putative chitobiose transporter
C L-Arabinose transporter
C Lactose/L-arabinose transporter
C L-Arabinose/D-xylose transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Oligogalacturonide transporter
C Alpha-1,4-digalacturonate transporter
C Putative aldouronate transporter
D SPy_1592 putative ABC transporter substrate binding lipoprotein K17318 lplA; putative aldouronate transport system substrate-binding protein
D SPy_1595 putative sugar-binding transport protein K17319 lplB; putative aldouronate transport system permease protein
D SPy_1593 putative sugar-binding transport protein K17320 lplC; putative aldouronate transport system permease protein
C Alpha-galactoside transporter
C Methyl-galactoside transporter
C D-Galactose transporter
C D-Xylose transporter
C Xylobiose transporter
C Fucose transporter
C Sugar transporter
C Multiple sugar transporter
C D-Allose transporter
C Fructose transporter
C Rhamnose transporter
C Ribose transporter
C Galactofuranose transporter
C Erythritol transporter
C Putative xylitol transporter
C Inositol transporter
C Inositol transporter
C Inositol-phosphate transporter
C Fructooligosaccharide transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Fructooligosaccharide transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Glycerol transporter
C Putative sn-Glycerol 3-phosphate transporter
C Putative sorbitol/mannitol transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Arabinooligosaccharide transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Arabinooligosaccharide transporter
C Polygalacturonan/rhamnogalacturonan transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Pectin-derived oligosaccharide transporter
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C General nucleoside transporter
D SPy_1228 putative lipoprotein K07335 bmpA; basic membrane protein A and related proteins
D SPy_0163 putative ABC transporter (lipoprotein) K07335 bmpA; basic membrane protein A and related proteins
D SPy_1226 putative sugar ABC transporter (permease protein) K23535 nupB; general nucleoside transport system permease protein
D SPy_1225 putative sugar ABC transporter (permease protein) K23536 nupC; general nucleoside transport system permease protein
D SPy_1227 putative sugar ABC transporter (ATP-binding protein) K23537 nupA; general nucleoside transport system ATP-binding protein
C Riboflavin transporter
C UDP-glucose/iron transporter
C AI-2 transporter
C gamma-Hexachlorocyclohexane transporter
C Phospholipid transporter
C Mce system transporter
C Putative multiple sugar transporter
D SPy_0252 putative sugar transporter sugar binding lipoprotein K02027 ABC.MS.S; multiple sugar transport system substrate-binding protein
D SPy_0254 sugar transport system (permease) K02025 ABC.MS.P; multiple sugar transport system permease protein
D SPy_0255 probable sugar transport protein (permease) K02026 ABC.MS.P1; multiple sugar transport system permease protein
D SPy_1976 msmK; multiple sugar-binding ABC transport system (ATP-binding protein) K10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]
C Putative simple sugar transporter
B Phosphate and amino acid transporters
C Phosphate transporter
D SPy_1245 pstS; putative phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D SPy_1244 pstC2; putative phosphate ABC transporter (permease protein) K02037 pstC; phosphate transport system permease protein
D SPy_1243 pstC; putative phosphate ABC transporter (permease protein) K02038 pstA; phosphate transport system permease protein
D SPy_1241 pstB; phosphate ABC transporter (ATP-binding protein) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D SPy_1242 pstB2; putative phosphate ABC transporter (ATP-binding protein) K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
C Phosphonate transporter
C Lysine/arginine/ornithine transporter
C Histidine transporter
C Glutamine transporter
D SPy_1315 hypothetical protein K10036 glnH; glutamine transport system substrate-binding protein
D SPy_1316 putative ABC transporter (ATP-binding protein) K10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]
C Arginine transporter
C Glutamate/aspartate transporter
C Aspartate/glutamate/glutamine transporter
C Octopine/nopaline transporter
C General L-amino acid transporter
C Glutamate transporter
C Cystine transporter
D SPy_0903 putative ABC transporter (binding protein) K02424 tcyA; L-cystine transport system substrate-binding protein
D SPy_0317 conserved hypothetical protein K02424 tcyA; L-cystine transport system substrate-binding protein
D SPy_0904 putative ABC transporter (permease) K10009 tcyB; L-cystine transport system permease protein
D SPy_1658 putative amino acid ABC transproter (permease protein) K10009 tcyB; L-cystine transport system permease protein
D SPy_1657 putative amino acid ABC transport system (ATP-binding protein) K10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]
C L-Cystine transporter
C Arginine/ornithine transporter
C Arginine/lysine/histidine/glutamine transporter
C Arginine/lysine/histidine transporter
D SPy_0778 putative ABC transporter (substrate-binding protein) K23059 artP; arginine/lysine/histidine transporter system substrate-binding protein
D SPy_1507 putative amino acid ABC transporter (permease protein) K17077 artQ; arginine/lysine/histidine transport system permease protein
D SPy_1506 putative amino acid ABC transporter (ATP-binding protein) K23060 artR; arginine/lysine/histidine transport system ATP-binding protein [EC:7.4.2.1]
C Hydroxyproline transporter
C Branched-chain amino acid transporter
C Neutral amino acid transporter
C D-Methionine transporter
D SPy_0319 conserved hypothetical protein K02073 metQ; D-methionine transport system substrate-binding protein
D SPy_0321 putative ABC transporter (permease protein) K02072 metI; D-methionine transport system permease protein
D SPy_0320 putative ABC transporter (ATP-binding protein)h K02071 metN; D-methionine transport system ATP-binding protein
C Urea transporter
C Putative tryptophan/tyrosine transporter
D SPy_1016 conserved hypothetical protein K01989 K01989; putative tryptophan/tyrosine transport system substrate-binding protein
D SPy_1018 putative ABC transport protein (permease) K05832 K05832; putative tryptophan/tyrosine transport system permease protein
D SPy_1019 putative ABC transporter (ATP-binding protein) K05833 K05833; putative tryptophan/tyrosine transport system ATP-binding protein
C Putative lysine transporter
D SPy_0277 putative glutamine-binding periplasmic protein K17073 lysX1; putative lysine transport system substrate-binding protein
D SPy_0276 putative amino acid ABC transporter (ATP-binding protein) K17076 lysY; putative lysine transport system ATP-binding protein
C Putative lysine/arginine/ornithine/histidine/octopine transporter
C Putative S-methylcysteine transporter
C Putative polar amino acid transporter
D SPy_1274 putative amino acid ABC transporter, periplasmic amino acid-binding protein K02030 ABC.PA.S; polar amino acid transport system substrate-binding protein
D SPy_1276 putative amino acid ABC transporter (permease protein) K02029 ABC.PA.P; polar amino acid transport system permease protein
D SPy_1275 putative amino acid ABC transporter (ATP-binding protein) K02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]
B Peptide and nickel transporters
C Oligopeptide transporter
D SPy_0294 oppB; oligopeptidepermease K15581 oppB; oligopeptide transport system permease protein
D SPy_0295 oppC; oligopeptidepermease K15582 oppC; oligopeptide transport system permease protein
D SPy_0296 oppD; oligopeptidepermease (ATP-binding protein) K15583 oppD; oligopeptide transport system ATP-binding protein
D SPy_0297 oppF; oligopeptidepermease K10823 oppF; oligopeptide transport system ATP-binding protein
C Dipeptide transporter
C Dipeptide transporter
C Cationic peptide transporter
C Nickel transporter
C Nickel transporter
C Glutathione transporter
C Peptides/nickel transporter
D SPy_2000 dppA; surface lipoprotein K02035 ABC.PE.S; peptide/nickel transport system substrate-binding protein
D SPy_2001 dppB; transmembrane transport protein K02033 ABC.PE.P; peptide/nickel transport system permease protein
D SPy_2002 dppC; transmembrane transport protein K02034 ABC.PE.P1; peptide/nickel transport system permease protein
D SPy_2003 dppD; ATPase protein K02031 ddpD; peptide/nickel transport system ATP-binding protein
D SPy_2004 dppE; ATPase protein K02032 ddpF; peptide/nickel transport system ATP-binding protein
C Microcin C transporter
B Metallic cation, iron-siderophore and vitamin B12 transporters
C Ferric citrate transporter
C Ferric hydroxamate transporter
C Ferric hydroxamate/heme transporter
D SPy_0385 fhuD; ferrichrome ABC transporter (ferrichrome-binding protein) K25308 fhuD; ferric hydroxamate/heme transport system substrate-binding protein
D SPy_0384 fhuB.1; putative ferrichrome ABC transporter (permease) K25288 fhuB; ferric hydroxamate/heme transport system permease protein
D SPy_0383 fhuG; putative ferrichrome ABC transporter (permease) K25289 fhuG; ferric hydroxamate/heme transport system permease protein
D SPy_0386 fhuA; putative ferrichrome ABC transporter (ATP-binding protein) K25290 fhuA; ferric hydroxamate/heme transport system ATP-binding protein [EC:7.2.2.16]
C Heme transporter
C Heme transporter
D SPy_1795 putative ABC transporter (periplasmic binding protein) K25113 htsA; heme transport system substrate-binding protein
D SPy_1794 putative ABC transporter (permease) K25114 htsB; heme transport system permease protein
D SPy_1793 putative ABC transporter (ATP-binding protein) K25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5]
D SPy_1796 hypothetical protein K25119 shp; heme transport system cell surface heme-binding protein
D SPy_1798 hypothetical protein sharing similarity with several eukaryotic proteins K25120 shr; heme sequestration protein
C Iron-siderophore transporter
C Iron-siderophore transporter
C Iron-siderophore transporter
C Iron complex transporter
C Vitamin B12 transporter
C Cobalamin transporter
C Manganese transporter
C Manganese transporter
C Zinc transporter
D SPy_0714 adcA; putative adhesion protein K09815 znuA; zinc transport system substrate-binding protein
D SPy_2007 lmb; putative laminin adhesion K09815 znuA; zinc transport system substrate-binding protein
D SPy_0094 adcB; putative ABC transporter (permease) K09816 znuB; zinc transport system permease protein
D SPy_0093 adcC; ABC transporter (ATP-binding protein) K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
C Iron/zinc/manganese/copper transporter
D SPy_0453 mtsA; metal binding protein of ABC transporter (lipoprotein) K11704 mtsA; iron/zinc/manganese/copper transport system substrate-binding protein
D SPy_0456 mtsC; ABC transporter (permease protein) K11705 mtsC; iron/zinc/manganese/copper transport system permease protein
D SPy_0454 mtsB; ABC transporter (ATP-binding protein) K11706 mtsB; iron/zinc/manganese/copper transport system ATP-binding protein
C Manganese/iron transporter
C Manganese/zinc transporter
C Manganese/zinc/iron transporter
C Manganese/iron transporter
C Cobalt transporter
C Nickel transporter
C Biotin transporter
D SPy_0207 putative biotin synthase K03523 bioY; biotin transport system substrate-specific component
C Energy-coupling factor transporter
D SPy_0207 putative biotin synthase K03523 bioY; biotin transport system substrate-specific component
D SPy_1789 hypothetical protein K16926 htsT; energy-coupling factor transport system substrate-specific component
D SPy_0603 hypothetical protein K16927 cbrT; energy-coupling factor transport system substrate-specific component
D SPy_2193 conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein
D SPy_1788 conserved hypothetical protein K16785 ecfT; energy-coupling factor transport system permease protein
D SPy_2195 ABC transporter (ATP-binding protein) K16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SPy_2194 putative ABC transporter (ATP-binding protein) K16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
D SPy_1787 putative ABC transporter (ATP-binding protein) K01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]
C Putative zinc/manganese transporter
B ABC-2 type and other transporters
C Multidrug/hemolysin transporter
C Capsular polysaccharide transporter
C Vi polysaccharide transporter
C Homopolymeric O-antigen
C Lipopolysaccharide transporter
C Teichoic acid transporter
C Lipooligosaccharide transporter
C Sodium transporter
C Lantibiotic transporter
C Lantibiotic transporter
D SPy_1086 srtE; conserved hypothetical protein - lantibiotic associated K20491 nisE; lantibiotic transport system permease protein
D SPy_1087 srtG; conserved hypothetical protein - lantibiotics associated K20492 nisG; lantibiotic transport system permease protein
D SPy_1085 srtF; ABC transporter (ATP-binding) - lantibiotic associated K20490 nisF; lantibiotic transport system ATP-binding protein
C Copper-processing transporter
C Gliding motility-associated transporter
C Putative peptide transporter
C Hemin transporter
C Daunorubicin/doxorubicin transporter
C Oleandomycin transporter
C Pyoluteorin transporter
C Drug efflux transporter
C Linearmycin/streptolysin S transporer
D SPy_0746 putative ABC transporter (ATP-binding protein) K25142 lnrN; linearmycin/streptolysin S transport system permease protein
D SPy_0745 sagH; ABC transporter (ATP-binding protein) - streptolysin S associated ORF K25143 lnrM; linearmycin/streptolysin S transport system permease protein
D SPy_0744 putative ABC transporter (ATP-binding protein) K25144 lnrL; linearmycin/streptolysin S transport system ATP-binding protein
C Bacitracin transporter
C Bacitracin transporter
C Bacitracin transporter
C Beta-exotoxin I transporter
C Polyether ionophore transporter
C Uncharacterized ABC transporter
C Cationic antimicrobial peptide transporter
C Fluoroquinolones transporter
C Lipoprotein-releasing transporter
C Acetoin utilization transporter
C Antimicrobial peptide resistance transporter
D SPy_0838 conserved hypothetical protein K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D SPy_2029 putative ABC transporter (ATP-binding protein) K24948 yknZ; antimicrobial peptide resistance transport system permease protein
D SPy_0837 putative ABC transporter (ATP-binding protein) K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
D SPy_2031 putative ABC transporter (ATP-binding protein) K24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]
C Heterocyst specific transporter
C Heme transporter
C Cell division transporter
D SPy_0645 ftsX; putative cell-division protein K09811 ftsX; cell division transport system permease protein
D SPy_0644 ftsE; putative cell-division ATP-binding protein K09812 ftsE; cell division transport system ATP-binding protein
C Viologen exporter family transporter
D SPy_0521 conserved hypothetical protein K25154 evrC; viologen exporter family transport system permease protein
D SPy_0519 conserved hypothetical protein K25155 evrB; viologen exporter family transport system permease protein
D SPy_0518 putative ABC transporter (ATP-binding protein) K25156 evrA; viologen exporter family transport system ATP-binding protein
C Antilisterial bacteriocin subtilosin biosynthesis transporter
C ABC-2 type transporter
D SPy_1728 putative ABC transporter (permease) K25157 ecsB; ABC-2 type transport system permease protein
D SPy_1729 putative ABC transporter (ATP-binding protein) K25158 ecsA; ABC-2 type transport system ATP-binding protein
C ABC-2 type transporter
D SPy_0789 rgpCc; putative ABC-transporter (permease protein) - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide K01992 ABC-2.P; ABC-2 type transport system permease protein
D SPy_1673 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SPy_1783 hypothetical protein K01992 ABC-2.P; ABC-2 type transport system permease protein
D SPy_1286 putative ABC transporter (ATP-binding protein) K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SPy_0790 rgpDc; ABC-transporter (ATP-binding protein) - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SPy_1674 putative ABC transporter (ATP-binding protein) K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
D SPy_1784 putative ABC transporter (ATP-binding protein) K01990 ABC-2.A; ABC-2 type transport system ATP-binding protein
C Putative ABC transporter
D SPy_1255 hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SPy_1911 salY; putative ABC transporter (permease) associated with salivaricin lantibiotic K02004 ABC.CD.P; putative ABC transport system permease protein
D SPy_0772 conserved hypothetical protein K02004 ABC.CD.P; putative ABC transport system permease protein
D SPy_1257 putative ABC transporter (ATP-binding protein) K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SPy_1912 salX; putative salivaricin A ABC transporter (ATP-binding protein) K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
D SPy_0773 putative ABC transporter (ATP-binding protein) K02003 ABC.CD.A; putative ABC transport system ATP-binding protein
C Orphan ABC ATPase
D SPy_0285 putative ABC transporter (ATP-binding protein) K09013 sufC; Fe-S cluster assembly ATP-binding protein
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ASolute carrier family (SLC)
B SLC1: High-affinity glutamate and neutral amino acid transporter
B SLC2: Facilitative GLUT transporter
B SLC3: Heavy subunits of the heteromeric amino acid transporters
B SLC4: Bicarbonate transporter
B SLC5: Sodium glucose cotransporter
B SLC6: Sodium- and chloride-dependent neurotransmitter transporter
B SLC7: Cationic amino acid transporter/glycoprotein-associated
B SLC8: Na+/Ca2+ exchanger
B SLC9: Na+/H+ exchanger
B SLC10: Sodium bile salt cotransporter
B SLC11: Proton-coupled metal ion transporter
B SLC12: Electroneutral cation-coupled Cl cotransporter
B SLC13: Human Na+-sulfate/carboxylate cotransporter
B SLC14: Urea transporter
B SLC15: Proton oligopeptide cotransporter
B SLC16: Monocarboxylate transporter
B SLC17: Vesicular glutamate transporter
B SLC18: Vesicular amine transporter
B SLC19: Folate/thiamine transporter
B SLC20: Type III Na+-phosphate cotransporter
B SLC21/ASLCO: Organic anion transporter
B SLC22: Organic cation/anion/zwitterion transporter
B SLC23: Na+-dependent ascorbic acid transporter
B SLC24: Na+/(Ca2+-K+) exchanger
B SLC25: Mitochondrial carrier
B SLC26: Multifunctional anion exchanger
B SLC27: Fatty acid transporter
B SLC28: Na+-coupled nucleoside transporter
B SLC29: Facilitative nucleoside transporter
B SLC30: Zinc efflux transporter
B SLC31: Copper transporter
B SLC32: Vesicular inhibitory amino acid transporter
B SLC33: Acetyl-CoA transporter
B SLC34: Type II Na+-phosphate cotransporter
B SLC35: Nucleoside-sugar transporter
B SLC36: Proton-coupled amino acid transporter
B SLC37: Sugar-phosphate/phosphate exchanger
B SLC38: System A and System N sodium-coupled neutral amino acid transporter
B SLC39: Metal ion transporter
B SLC40: Basolateral iron transporter
B SLC41: MgtE-like magnesium transporter
B SLC42: Rh ammonium transporter
B SLC43: Na+-independent, system-L-like amino acid transporter
B SLC44: Choline-like transporter
B SLC45: H+/sugar cotransporter
B SLC46: Folate transporter
B SLC47: Multidrug and Toxin Extrusion (MATE) family
C SPy_0045 conserved hypothetical protein K26937 dinF; MATE family, multidrug efflux pump
B SLC48: Heme transporter
B SLC49: FLVCR-related transporter
B SLC50: Sugar efflux transporter
B SLC51: Transporter of steroid-derived molecules
B SLC52: Riboflavin transporter
B SLC54: Mitochondrial pyruvate carrier
B SLC56: Sideroflexin
B SLC57: NiPA-like magnesium transporter
B SLC58: MagT-like magnesium transporter
B SLC62: Pyrophosphate transporter
B SLC65: NPC-type cholesterol transporter
B SLC66: Lysosomal lysine-arginine transporter
#
AMajor facilitator superfamily (MFS)
B Sugar transporters
C Sugar porter (SP) family [TC:2.A.1.1]
C Oligosaccharide:H+ symporter (OHS) family [TC:2.A.1.5]
C Fucose:H+ symporter (FHS) family [TC:2.A.1.7]
C Sugar efflux transporter (SET) [TC:2.A.1.20]
C Nucleoside:H+ symporter (NHS) family [TC:2.A.1.10]
C N-Acetylglucosamine transporter (NAG-T) family [TC:2.A.1.58]
B Organic acid transporters
C Metabolite:H+ symporter (MHS) family [TC:2.A.1.6]
C Oxalate:formate antiporter (OFA) family [TC:2.A.1.11]
D SPy_1392 putative oxalate:formate antiporter K08177 oxlT; MFS transporter, OFA family, oxalate/formate antiporter
C Sialate:H+ symporter (SHS) family [TC:2.A.1.12]
C Monocarboxylate transporter (MCT) family [TC:2.A.1.13]
C Anion:cation symporter (ACS) family [TC:2.A.1.14]
C Aromatic acid:H+ symporter (AAHS) family [TC:2.A.1.15]
C Cyanate porter (CP) family [TC:2.A.1.17]
C Organic cation transporter (OCT) family [TC:2.A.1.19]
C Phenylproprionate permease (PPP) [TC:2.A.1.27]
C L-Amino acid transporter-3 (LAT3) family (SLC43 family) [TC:2.A.1.44]
C Proton coupled folate transporter/heme carrier protein (PCFT/HCP) family [TC:2.A.1.50]
B Phosphate and organophosphate transporters
C Phosphate:H+ symporter (PHS) family [TC:2.A.1.9]
C Organophosphate:Pi antiporter (OPA) family [TC:2.A.1.4]
D SPy_0442 putative glycerol-3-phosphate transporter K02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter
C 1-Arseno-3-phosphoglycerate exporter (APGE) family [TC:2.A.1.83]
B Nitrate/nitrite transporters
C Nitrate/nitrite porter (NNP) family [TC:2.A.1.8]
C Proton-dependent oligopeptide transporter (POT/PTR) family [TC:2.A.17]
B Lipid transporters
C Lysophospholipid transporter (LplT) family [TC:2.A.1.42]
C Sphingosine-1-phosphate transporter (Spinster) family [TC:2.A.1.49]
B Metal transporters
C Siderophore-iron transporter (SIT) family [TC:2.A.1.16]
C Enterobactin (siderophore) exporter (EntS) family [TC:2.A.1.38]
C Nickel resistance (Nre) family [TC:2.A.1.31]
C MFS domain-containing protein family [TC:2.A.1.40]
C Putative bacteriochlorophyll delivery (BCD) family [TC:2.A.1.41]
B Protein transporters
C Vesicular neurotransmitter transporter (VNT) [TC:2.A.1.22]
C Peptide-acetyl-CoA transporter (PAT) [TC:2.A.1.25]
C Feline leukemia virus subgroup C receptor (FLVCR) [TC:2.A.1.28]
B Drug transporters
C Drug:H+ antiporter-1 (12 spanner) (DHA1) family [TC:2.A.1.2]
D SPy_0501 putative multi-drug resistance efflux pump K08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein
D SPy_2120 lmrP; putative integral membrane protein K08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B
C Drug:H+ antiporter-2 (14 spanner) (DHA2) family [TC:2.A.1.3]
D SPy_0570 putative drug resistance protein K18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein
C Drug:H+ antiporter-3 (12 spanner) (DHA3) [TC:2.A.1.21]
C Putative aromatic compound/drug exporter (ACDE) family [TC:2.A.1.32]
C Fosmidomycin resistance (Fsr) family [TC:2.A.1.35]
C Acriflavin-sensitivity (YnfM) family [TC:2.A.1.36]
C Glycerophosphodiester uptake (GlpU) family [TC:2.A.1.52]
B Unknown transporters
C Unknown major facilitator-1 (UMF1) [TC:2.A.1.24]
C Unknown major facilitator-2 (UMF2) [TC:2.A.1.26]
C Putative YqgE transporter (YqgE) family [TC:2.A.1.33]
C Others
#
APhosphotransferase system (PTS)
B Enzyme I and HPr
C Enzyme I [TC:8.A.7]
D SPy_1372 pstI; putative phosphoenolpyruvate:sugar phosphotransferase system enzyme I K08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]
C Phosphocarrier protein HPr [TC:8.A.8]
D SPy_1373 ptsH; putative phosphotransferase system phosphohistidine-containing protein K02784 ptsH; phosphocarrier protein HPr
C Multiphosphoryl transfer protein
B Enzyme II [TC:4.A]
C Glucose-specific II component
C Glucose-specific II component
C N-Acetylglucosamine-specific II component
C Maltose/glucose-specific II component
C Maltose-specific II component
D SPy_1986 putative PTS system, enzyme II, A component K20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]
C D-Glucosamine-specific II component
C Sucrose-specific II component
D SPy_1815 scrA; putative sucrose-specific PTS permease, enzyme II K02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]
C Beta-glucoside-specific II component
D SPy_0572 beta-glucoside permease IIABC component K02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]
C Beta-glucoside (arbutin/salicin/cellobiose)-specific II component
C Trehalose-specific II component
D SPy_2097 putative PTS system enzyme II K02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]
C N-Acetylmuramic acid-specific II component
C Alpha-glucoside-specific II component
C Fructose-specific II component
D SPy_0855 putative fructose-specific enzyme II, PTS system BC component K02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]
C Fructose-specific II-like component
C Mannitol-specific II component
C 2-O-A-Mannosyl-D-glycerate-specific II component
C Lactose-specific II component
D SPy_1918 lacF; putative PTS system, lactose-specific component IIA K02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]
D SPy_1917 lacE; putative PTS system, lactose-specific component IIBC K02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]
C Cellobiose-specific II component
D SPy_2052 putative PTS system, enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SPy_1323 putative PTS enzyme III K02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]
D SPy_2051 putative PTS system, enzyme IIB K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SPy_1324 putative PTS system enzyme II K02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]
D SPy_2050 putative PTS system, enzyme IIC component K02761 celB; cellobiose PTS system EIIC component
C Glucitol/sorbitol-specific II component
C Galactitol-specific II component
C Galactose-specific II component
D SPy_1711 putative PTS system, enzyme IIA component K20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]
D SPy_1710 putative PTS system, enzyme IIB component K20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]
D SPy_1709 putative PTS system, enzyme IIC component K20114 gatC; galactose PTS system EIIC component
C Mannose-specific II component
C Mannose-specific II component
D SPy_1738 manL; mannose-specific phosphotransferase system component IIAB K02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]
D SPy_1057 hypothetical protein K02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]
D SPy_1739 manM; putative mannose-specific phosphotransferase system component IIC K02795 manY; mannose PTS system EIIC component
D SPy_1059 putative phospotransferase system (PTS), enzyme II, component C K02795 manY; mannose PTS system EIIC component
D SPy_1740 manN; putative mannose-specific phosphotransferase system component IID K02796 manZ; mannose PTS system EIID component
D SPy_1060 putative phospotransferase system (PTS), enzyme II component D K02796 manZ; mannose PTS system EIID component
C Fructoselysine/glucoselysine-specific II component
D SPy_1058 putative phosphotransferase system (PTS), enzyme II component B K19507 gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-]
C Fructose-specific II component
C Sorbose-specific II component
C N-Acetylgalactosamine-specific II component
D SPy_0634 agaF; putative PTS dependent N-acetyl-galactosamine- and galactosamine IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
D SPy_0631 agaV; putative PTS dependent N-acetyl-galactosamine-IIB component K02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]
D SPy_0630 agaW; putative PTS dependent N-acetyl-galactosamine-IIC component K02746 agaW; N-acetylgalactosamine PTS system EIIC component
D SPy_0629 agaD; putative PTS dependent galactosamine IID component K02747 agaE; N-acetylgalactosamine PTS system EIID component
C Galactosamine-specific II component
D SPy_0634 agaF; putative PTS dependent N-acetyl-galactosamine- and galactosamine IIA component K02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]
C D-Glucosaminate-specific II component
C Ascorbate-specific II component
D SPy_0176 conserved hypothetical protein K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SPy_1952 conserved hypothetical protein K02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]
D SPy_0175 conserved hypothetical protein K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SPy_1950 conserved hypothetical protein K02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]
D SPy_0174 conserved hypothetical protein K03475 ulaA; ascorbate PTS system EIIC component
D SPy_1949 conserved hypothetical protein K03475 ulaA; ascorbate PTS system EIIC component
C Nitrogen regulatory II component
C EI/HPr/EIIA hybrid protein
#
AOther transporters
B Aquaporins and small neutral solute transporters [TC:1.A.8]
C Aquaporins
C Aquaglyceroporins or glycerol-uptake facilitators
D SPy_1854 glpF.2; putative glycerol uptake facilitator protein K02440 glpF; glycerol uptake facilitator
D SPy_1682 glpF; putative glycerol uptake facilitator K02440 glpF; glycerol uptake facilitator
B Pores ion channels [TC:1]
C SPy_0917 hypothetical protein K00799 GST; glutathione S-transferase [EC:2.5.1.18]
C SPy_1424 putative formate dehydrogenase K21993 fdhC; formate transporter
C SPy_0780 mscL; putative large conductance mechanosensitive channel K03282 mscL; large conductance mechanosensitive channel
C SPy_1897 conserved hypothetical protein K22044 ybiO; moderate conductance mechanosensitive channel
C SPy_1827 putative divalent cation transport protein K03284 corA; magnesium transporter
C SPy_0378 hlyX; putative hemolysin K03699 tlyC; magnesium and cobalt exporter, CNNM family
B Electrochemical potential-driven transporters [TC:2]
C SPy_0845 czcD; putative cation-efflux system membrane protein K16264 czcD; cobalt-zinc-cadmium efflux system protein
C SPy_2205 conserved hypothetical protein K05340 glcU; glucose uptake protein
C SPy_0324 putative sodium/dicarboxylate symporter K07862 sstT; serine/threonine transporter
C SPy_0327 ntpJ; putative V-type Na+ -ATPase subunit J K03498 trkH; trk/ktr system potassium uptake protein
C SPy_0326 conserved hypothetical protein K03499 trkA; trk/ktr system potassium uptake protein
C SPy_0831 pyrP; putative uracil permease K02824 uraA; uracil permease
C SPy_1137 putative purine permease K16169 pbuX; xanthine permease
C SPy_1736 conserved hypothetical protein K06901 pbuG; adenine/guanine/hypoxanthine permease
C SPy_1114 conserved hypothetical protein K03281 clcA; chloride channel protein, CIC family
C SPy_1379 putative chloride channel protein K03281 clcA; chloride channel protein, CIC family
C SPy_0723 putative transposase K03281 clcA; chloride channel protein, CIC family
C SPy_1695 conserved hypothetical protein K03324 yjbB; phosphate:Na+ symporter
C SPy_1414 putative cation (K+) transport protein K03549 kup; KUP system potassium uptake protein
C SPy_0373 conserved hypothetical protein K23675 fmnP; riboflavin transporter
C SPy_0600 conserved hypothetical protein K16789 thiT; thiamine transporter
C SPy_1425 hypothetical protein K16788 niaX; niacin transporter
C SPy_0609 ftsW; putative cell division protein K03588 ftsW; cell division protein FtsW
B Primary active transporters [TC:3]
C SPy_1177 putative methylmalonyl-CoA decarboxylase, beta-subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
C SPy_1184 putative decarboxylase, beta subunit K20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]
C SPy_1174 putative transcarboxylase subunit K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
C SPy_1191 oadA; putative oxaloacetate decarboxylase alpha chain K01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]
C SPy_1175 hypothetical protein K01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma
C SPy_1176 putative methylmalonyl-CoA decarboxylase, gamma-subunit K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
C SPy_1183 putative decarboxylase, gamma chain K23351 gcdC; glutaconyl-CoA/methylmalonyl-CoA decarboxylase subunit gamma
B Transmembrane electron carriers [TC:5]
C SPy_1559 ccdA; putative cytochrome C-type biogenesis protein K06196 ccdA; cytochrome c-type biogenesis protein
B Accessory factors involved in transport [TC:8]
C SPy_2032 putative ATP-binding cassette transporter-like protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
C SPy_0836 conserved hypothetical protein K24950 yknX; membrane fusion protein, antimicrobial resistance system
B Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024
#
ABC classifications based on Igarashi et al. (2004) and Tomii & Kanehisa (1998)
#
MFS classification taken from TCDB