+D	Chaperone	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Chaperones and Folding Catalysts - Streptococcus pyogenes M1 GAS (serotype M1)</h2>
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A<b>Heat shock proteins</b>
B  HSP110
B  HSP100
C    SPy_2073 clpC; putative endopeptidase Clp ATP-binding chain C	K03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC 
C    SPy_1509 clpE; putative ATP-dependent protease	K03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE 
C    SPy_0888 clpL; putative ATP-dependent Clp proteinase (ATP-binding subunit)	K04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL 
C    SPy_0885 clpX; putative ATP-dependent Clp protease subunit X	K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX 
B  HSP90
B  HSP70 / DNAK
C    SPy_1760 dnaK; heat shock protein 70	K04043 dnaK; molecular chaperone DnaK 
B  HSP60 / Chaperonin
C    SPy_2070 groEL; heat shock protein (chaperonin)	K04077 groEL; chaperonin GroEL [EC:5.6.1.7] 
B  HSP47
B  HSP40 / DNAJ
C    SPy_1759 dnaJ; heat-shock (chaperone) protein	K03686 dnaJ; molecular chaperone DnaJ 
B  HSP33
C    SPy_0123 putative heat shock protein HSP33	K04083 hslO; molecular chaperone Hsp33 
B  HSP24
C    SPy_1761 grpE; putative Hsp-70 cofactor	K03687 GRPE; molecular chaperone GrpE 
B  HSP20
B  HSP15
B  HSP10
C    SPy_2072 groES; heat shock protein - cochaperonin	K04078 groES; chaperonin GroES 
B  GimC
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A<b>Other chaperones and cochaperones</b>
B  Calnexin / calreticulin
B  DegP / HtrA
C    SPy_2216 htrA; putative serine protease	K04771 degP; serine protease Do [EC:3.4.21.107] 
B  AAA proteases
C    SPy_0015 ftsH; putative cell division protein	K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] 
B  PapD
C    SPy_0755 atpB; putative proton-translocating ATPase a subunit	K02108 ATPF0A; F-type H+-transporting ATPase subunit a 
B  SecB
B  Sti1 / p60
B  Cdc37 / p50
B  BAG
B  Others
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A<b>Intramolecular chaperones</b>
B  Subtilisin family
C    SPy_0416 prtS; putative cell envelope proteinase	K01361 E3.4.21.96; lactocepin [EC:3.4.21.96] 
C    SPy_2010 scpA; C5A peptidase precursor	K08652 C5AP; C5a peptidase [EC:3.4.21.110] 
B  Papain family
B  Other peptidases
B  Others
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A<b>Protein folding catalysts</b>
B  Peptidyl prolyl isomerase
C    Cyclophilin
D      SPy_0457 putative cyclophilin-type protein	K03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] 
C    FKBP
D      SPy_1390 putative protease maturation protein	K07533 prsA; foldase protein PrsA [EC:5.2.1.8] 
D      SPy_2037 conserved hypothetical	K07533 prsA; foldase protein PrsA [EC:5.2.1.8] 
C    Parvulin
B  Protein disulfide isomerase
C    SPy_1835 trx; putative thioredoxin	K03671 TXN; thioredoxin 
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#Last updated: April 3, 2025