+F Repair protein KO #

  DNA Repair and Recombination Proteins - Streptococcus pyogenes HSC5 (serotype M14)

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D L897_06170 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E L897_03705 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E L897_07805 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E L897_03825 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D L897_03860 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D L897_06195 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D L897_01145 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D L897_06170 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E L897_03705 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E L897_07805 adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E L897_08960 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E L897_02230 5-hydroxymethyluracil DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E L897_03825 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E L897_01855 exodeoxyribonuclease K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] D RecJ E L897_03810 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D DNA ligase E L897_03045 DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E L897_01030 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E L897_07450 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A E L897_05340 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B E L897_04075 excinuclease ABC subunit C K03703 uvrC; excinuclease ABC subunit C E L897_04830 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E L897_01030 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E L897_03045 DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F L897_00660 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F L897_00665 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F L897_00515 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F L897_08055 DNA-directed RNA polymerase subunit delta K03048 rpoE; DNA-directed RNA polymerase subunit delta F L897_06710 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F L897_00030 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors E L897_08980 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS E L897_07825 DNA mismatch repair protein MutS K07456 mutS2; DNA mismatch repair protein MutS2 D Molecular matchmaker E L897_08975 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL D Strand discrimination factor D DNA exonucleases E L897_06155 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E L897_06150 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E L897_04890 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E L897_08380 DNA polymerase III PolC K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7] E L897_00010 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E L897_05700 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E L897_01795 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E L897_07925 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E L897_05545 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E L897_03045 DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E L897_04830 ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E L897_00755 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E L897_07785 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E L897_07850 exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E L897_08950 recombinase RecA K03553 recA; recombination protein RecA E L897_08965 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E L897_00345 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E L897_06705 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] D RecFOR pathway proteins E L897_08950 recombinase RecA K03553 recA; recombination protein RecA E L897_01150 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms E L897_09210 recombinase RecF K03629 recF; DNA replication and repair protein RecF E L897_07325 ATP-dependent DNA helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E L897_03810 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E L897_00260 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E L897_05760 recombinase RecR K06187 recR; recombination protein RecR E L897_06130 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) E L897_06785 Holliday junction resolvase K03700 recU; recombination protein U E L897_08965 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA E L897_00345 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] D AddAB pathway proteins E L897_03160 ATP-dependent helicase K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] E L897_03155 ATP-dependent helicase K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D Other HR factor D Archaeal homologous recombinant proteins E L897_02240 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F L897_04365 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F L897_02970 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F L897_04415 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F L897_06105 transcriptional regulator K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F L897_06000 hypothetical protein K07455 recT; recombination protein RecT F L897_07670 recombinase RecT K07455 recT; recombination protein RecT F L897_03810 single-stranded DNA exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] F L897_00260 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F L897_05760 recombinase RecR K06187 recR; recombination protein RecR F L897_03045 DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F L897_07450 uvrA; excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A F L897_05340 excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D L897_07860 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D L897_08950 recombinase RecA K03553 recA; recombination protein RecA D L897_06130 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D L897_00755 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D L897_07785 single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D L897_06565 recX; recombinase RecX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D L897_02880 helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] C Modulation of nucleotide pools D L897_03860 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D L897_06195 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D L897_01145 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D L897_01895 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D L897_05600 ribonucleotide-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D L897_01885 ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] D L897_05605 ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D L897_02935 oligoribonuclease K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 10, 2025