+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Serratia quinivorans
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C E4343_13120 lipoprotein signal peptidase K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C E4343_19580 prepilin peptidase K02464 gspO; general secretion pathway protein O [EC:3.4.23.43 2.1.1.-]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
C E4343_04035 hycI; hydrogenase maturation peptidase HycI K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51]
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
C E4343_01050 pcp; pyroglutamyl-peptidase I K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
C E4343_09960 pcp; pyroglutamyl-peptidase I K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C E4343_03395 glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C E4343_19190 glutamine amidotransferase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C E4343_22770 guaA; glutamine-hydrolyzing GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C E4343_05880 puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase K09473 puuD; gamma-glutamyl-gamma-aminobutyrate hydrolase [EC:3.5.1.94]
B Family C27
B Family C30
B Family C37
B Family C39
C E4343_04605 peptidase domain-containing ABC transporter K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
B Family C40
C E4343_24570 mepS; bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase K13694 mepS; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]
C E4343_05195 peptidoglycan endopeptidase K19303 mepH; murein DD-endopeptidase [EC:3.4.-.-]
C E4343_05405 endopeptidase K13695 nlpC; probable lipoprotein NlpC
B Family C44
C E4343_24125 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C E4343_19050 gltB; glutamate synthase large subunit K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C E4343_16220 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C E4343_10155 asparagine synthase B K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C E4343_03850 DJ-1/PfpI family protein K05520 yhbO; deglycase [EC:3.5.1.124]
C E4343_11050 yajL; protein deglycase YajL K03152 thiJ; protein deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
C E4343_13660 L,D-transpeptidase K19235 ybiS; L,D-transpeptidase YbiS
C E4343_05275 L,D-transpeptidase K19236 ycfS; L,D-transpeptidase YcfS
C E4343_07505 ldtD; L,D-transpeptidase K21470 ycbB; L,D-transpeptidase YcbB
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C E4343_09765 CPBP family intramembrane metalloprotease K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C E4343_07460 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
B Family M3
C E4343_17245 prlC; oligopeptidase A K01414 prlC; oligopeptidase A [EC:3.4.24.70]
C E4343_04660 dcp; peptidyl-dipeptidase Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
C E4343_04255 matrixin family metalloprotease K01406 prtC; serralysin [EC:3.4.24.40]
C E4343_15205 matrixin family metalloprotease K01406 prtC; serralysin [EC:3.4.24.40]
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
C E4343_04465 ddpX; D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
C E4343_23320 M15 family peptidase K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-]
B Family M16: pitrilysin family
C E4343_21340 pitrilysin K01407 ptrA; protease III [EC:3.4.24.55]
B Family M17: leucyl aminopeptidase family
C E4343_01810 leucyl aminopeptidase family protein K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C E4343_13850 pepA; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C E4343_22635 pepB; aminopeptidase PepB K07751 pepB; PepB aminopeptidase [EC:3.4.11.23]
B Family M18
B Family M19: membrane dipeptidase family
B Family M20
C E4343_23175 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C E4343_06095 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
C E4343_23960 pepT; peptidase T K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
C E4343_11680 pepD; beta-Ala-His dipeptidase K01270 pepD; dipeptidase D [EC:3.4.13.-]
C E4343_24770 amidohydrolase K01451 hipO; hippurate hydrolase [EC:3.5.1.32]
C E4343_19755 amidohydrolase K12940 abgA; aminobenzoyl-glutamate utilization protein A
C E4343_19750 amidohydrolase K12941 abgB; aminobenzoyl-glutamate utilization protein B
C E4343_11815 hpxK; allantoate amidohydrolase K02083 allC; allantoate deiminase [EC:3.5.3.9]
B Family M23
C E4343_02210 mepM; murein DD-endopeptidase MepM K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]
B Family M24
C E4343_09330 map; type I methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C E4343_21475 map; type I methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C E4343_14945 pepQ; Xaa-Pro dipeptidase K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C E4343_20800 pepP; Xaa-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
C E4343_12485 aminopeptidase K09612 iap; alkaline phosphatase isozyme conversion protein [EC:3.4.11.-]
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
C E4343_03260 carboxypeptidase M32 K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C E4343_14245 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C E4343_05620 htpX; protease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C E4343_20615 metalloprotease K07387 K07387; metalloprotease [EC:3.4.24.-]
C E4343_23095 M48 family peptidase K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C E4343_21515 rseP; sigma E protease regulator RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
C E4343_23890 mepA; penicillin-insensitive murein endopeptidase K07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]
B Family M80
B Family M82
B Family M85
B Family M88
B Family M90
C E4343_00470 mtfA; DgsA anti-repressor MtfA K09933 mtfA; MtfA peptidase
B Family M98
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C E4343_03250 serine protease K04775 ydgD; protease YdgD [EC:3.4.21.-]
C E4343_12650 degP; serine endoprotease DegP K04771 degP; serine protease Do [EC:3.4.21.107]
C E4343_19010 degQ; serine endoprotease DegQ K04772 degQ; serine protease DegQ [EC:3.4.21.-]
C E4343_19005 serine endoprotease DegS K04691 hhoB; serine protease DegS [EC:3.4.21.-]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
B Family S9: prolyl oligopeptidase family
C E4343_05000 S9 family peptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C E4343_06460 oligopeptidase B K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
C E4343_23360 S9 family peptidase K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C E4343_02930 dacD; serine-type D-Ala-D-Ala carboxypeptidase DacD K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C E4343_07980 serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C E4343_10305 serine-type D-Ala-D-Ala carboxypeptidase K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C E4343_03415 peptidase S11 K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
C E4343_09395 D-alanyl-D-alanine endopeptidase K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
C E4343_13475 ampH; D-alanyl-D-alanine-carboxypeptidase/endopeptidase AmpH K18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase [EC:3.4.16.4 3.4.21.-]
B Family S13: D-Ala-D-Ala peptidase C family
C E4343_14265 dacB; serine-type D-Ala-D-Ala carboxypeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C E4343_06250 ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
C E4343_10975 clpP; ATP-dependent Clp endopeptidase proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C E4343_10965 endopeptidase La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C E4343_07370 Lon protease family protein K04770 lonH; Lon-like ATP-dependent protease [EC:3.4.21.-]
B Family S21: assemblin family
B Family S24: LexA family
C E4343_18485 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
C E4343_03090 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-]
B Family S26: signal peptidase I family
C E4343_22385 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C E4343_06445 pip; prolyl aminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
B Family S41: C-terminal processing peptidase family
C E4343_05625 carboxy terminal-processing peptidase K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
B Family S45
C E4343_00305 penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11]
B Family S49: protease IV family
C E4343_02460 sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
C E4343_02810 sohB; protease SohB K04774 sohB; serine protease SohB [EC:3.4.21.-]
B Family S50
B Family S51
C E4343_14975 pepE; dipeptidase PepE K05995 pepE; dipeptidase E [EC:3.4.13.21]
B Family S53
B Family S54: Rhomboid family
C E4343_17560 glpG; rhomboid family intramembrane serine protease GlpG K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
B Family S77: phage prohead processing peptidase family
B Family S78
C E4343_22185 HK97 family phage prohead protease K06904 GP4; Escherichia/Staphylococcus phage prohead protease
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AThreonine peptidases
B Family T1: proteasome family
C E4343_16845 hslV; ATP-dependent protease subunit HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C E4343_08395 isoaspartyl peptidase/L-asparaginase K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
B Family T3: gamma-glutamyltransferase family
C E4343_03805 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C E4343_11175 ggt; gamma-glutamyltransferase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C E4343_11850 gamma-glutamyltransferase K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126]
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APeptidases of unknown catalytic type
B Family U32
C E4343_22905 U32 family peptidase K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C E4343_14125 U32 family peptidase K24845 ubiV; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiV [EC:1.97.1.15]
C E4343_14120 U32 family peptidase K24844 ubiU; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiU [EC:1.97.1.15]
B Family U62
C E4343_18845 pmbA; metalloprotease PmbA K03592 pmbA; PmbA protein
C E4343_18760 tldD; metalloprotease TldD K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
C E4343_07935 eco; serine protease inhibitor ecotin K08276 eco; ecotin
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
C E4343_22665 alpha-2-macroglobulin family protein K06894 yfhM; alpha-2-macroglobulin
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C E4343_14495 hflC; protease modulator HflC K04087 hflC; modulator of FtsH protease HflC
C E4343_14500 hflK; FtsH protease activity modulator HflK K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 20, 2025
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Classification taken and modified from MEROPS