+F Repair protein KO
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DNA Repair and Recombination Proteins - Salinibacter ruber M8
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SRM_01280 phrB; Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SRM_02554 phrB; Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SRM_01967 phrB; Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E SRM_01744 alkA; DNA-3-methyladenine glycosylase II K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SRM_02341 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SRM_02577 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D SRM_00960 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SRM_02177 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D SRM_01280 phrB; Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SRM_02554 phrB; Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SRM_01967 phrB; Deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D SRM_02252 Deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E SRM_00026 dbh2; DNA polymerase-related protein,bacteriophage-type K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E SRM_01744 alkA; DNA-3-methyladenine glycosylase II K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E SRM_02341 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E SRM_02577 nth; Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E SRM_03017 nfi; Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
E SRM_p56014 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SRM_02461 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E SRM_01077 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E SRM_01836 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E SRM_00525 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E SRM_02606 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E SRM_01341 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E SRM_01777 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E SRM_p56012 pcrA; ATP-dependent DNA helicase pcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_00621 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_00593 uvrD; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_00897 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_02541 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_01836 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E SRM_01077 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F SRM_01971 rpoB; DNA-directed RNA polymerase beta chain K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F SRM_01970 rpoC; DNA-directed RNA polymerase beta' chain K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F SRM_01261 rpoA; DNA-directed RNA polymerase alpha chain K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F SRM_00062 mfd; Transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E SRM_01808 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E SRM_00825 mutS2; DNA mismatch repair protein MutS2 K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E SRM_01919 mutL; DNA mismatch repair protein mutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E SRM_00914 xseA; Probable exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E SRM_00911 xseB; Probable exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E SRM_01173 dnaE2; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E SRM_00003 dnaN; DNA polymerase III, beta chain K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E SRM_00580 holA; DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E SRM_01041 dnaX; DNA polymerase III gamma/tau subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E SRM_01633 dnaQ; DNA polymerase III epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SRM_01143 polC; DNA polymerase III polC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SRM_00894 dnaQ; DNA polymerase III, epsilon chain K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E SRM_02776 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E SRM_01077 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E SRM_p56012 pcrA; ATP-dependent DNA helicase pcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_00621 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_00593 uvrD; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_00897 pcrA; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_02541 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E SRM_00604 ssb; Single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E SRM_00895 ssb; Single-strand binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E SRM_01730 recA; RecA protein K03553 recA; recombination protein RecA
E SRM_00534 ruvA; Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E SRM_01326 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SRM_02885 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E SRM_02956 priA; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E SRM_02076 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SRM_00863 sbcD; Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E SRM_02224 sbcD; DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E SRM_01730 recA; RecA protein K03553 recA; recombination protein RecA
E SRM_02716 radA; DNA repair protein radA homolog K04485 radA; DNA repair protein RadA/Sms
E SRM_00068 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF
E SRM_00344 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E SRM_p56014 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SRM_02461 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E SRM_01362 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
E SRM_02774 recR; Recombination protein recR K06187 recR; recombination protein RecR
E SRM_00978 recN; DNA repair protein recN K03631 recN; DNA repair protein RecN (Recombination protein N)
E SRM_00534 ruvA; Holliday junction DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA
E SRM_01326 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E SRM_02885 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E SRM_02515 mcrA; putative helicase K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E SRM_02076 sbcC; exonuclease SbcC K03546 sbcC; DNA repair protein SbcC/Rad50
E SRM_00863 sbcD; Exonuclease SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E SRM_02224 sbcD; DNA repair exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F SRM_02425 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SRM_01676 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F SRM_01677 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SRM_02628 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F SRM_01297 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F SRM_01572 himA; Histone-like bacterial DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F SRM_p56014 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SRM_02461 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F SRM_01362 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O)
F SRM_02774 recR; Recombination protein recR K06187 recR; recombination protein RecR
F SRM_01077 ligA; NAD-dependent DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F SRM_01264 hup; DNA-binding protein HU K05788 ihfB; integration host factor subunit beta
E Supressor
F SRM_p56018 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SRM_00373 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SRM_01878 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F SRM_00525 uvrA; Excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F SRM_02606 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F SRM_01341 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D SRM_01738 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SRM_p56036 dinP; DNA polymerase IV, damage-inducible protein P K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D SRM_00381 umuC; Protein umuC K03502 umuC; DNA polymerase V
D SRM_00380 umuD; umuD protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D SRM_01730 recA; RecA protein K03553 recA; recombination protein RecA
D SRM_00637 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SRM_01363 lexA2; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D SRM_00978 recN; DNA repair protein recN K03631 recN; DNA repair protein RecN (Recombination protein N)
D SRM_00604 ssb; Single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D SRM_00895 ssb; Single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D SRM_02357 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
D SRM_01886 pol4; DNA polymerase IV (family X) K02347 polX; DNA polymerase (family X)
C DNA helicases
C Modulation of nucleotide pools
D SRM_00960 MutT/nudix family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D SRM_02466 hydrolase, NUDIX family protein K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D SRM_02177 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D SRM_00377 nrdB; ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SRM_00154 nrdA; Ribonucleoside-diphosphate reductase large chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D SRM_00153 nrdB; Ribonucleoside-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D SRM_01202 Dhh family/dhha1 domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024