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Transfer RNA Biogenesis - Streptomyces rubrolavendulae
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AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D A4G23_01614 rnz_1; Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D A4G23_02756 cca; CCA-adding enzyme K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D A4G23_02879 rtcB_1; RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D A4G23_03205 rtcB_2; RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D A4G23_02878 putative protein archease K24956 ZBTB8OS; protein archease
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D A4G23_04106 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D A4G23_04223 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D A4G23_01265 ileS; Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D A4G23_01640 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D A4G23_02655 metG_1; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D A4G23_03545 metG_2; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D A4G23_03200 argS_1; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D A4G23_03943 argS_2; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D A4G23_03108 lysX_1; Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D A4G23_02657 aspS; Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D A4G23_00745 alaS_1; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D A4G23_01593 glyQS; Glycine--tRNA ligase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D A4G23_00776 thrS; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D A4G23_02803 serS; Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D A4G23_02471 cysS; Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D A4G23_01693 valS; Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D A4G23_00752 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D A4G23_00838 pheS; Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D A4G23_00837 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D A4G23_01051 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D A4G23_03156 trpS_1; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D A4G23_03511 trpS_2; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D A4G23_02517 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
C AARS associated factors
D A4G23_01615 hinT; HIT-like protein HinT K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
C Methyltransferases
D A4G23_00884 trmI; tRNA (adenine(58)-N(1))-methyltransferase TrmI K07442 TRM61; tRNA (adenine57-N1/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]
D A4G23_02593 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
C Psudouridine synthases
D A4G23_03397 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D A4G23_04234 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D A4G23_01341 iscS_1; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D A4G23_04054 iscS_2; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D A4G23_03954 ywlC_1; Threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D A4G23_04302 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D A4G23_02741 ribonuclease P K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
B 3'processing and CCA adding factors
C 3'processing factors
D A4G23_01614 rnz_1; Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D A4G23_01922 rph; Ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
D A4G23_04642 rnd; Ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
C CCA adding factors
D A4G23_02756 cca; CCA-adding enzyme K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D A4G23_02879 rtcB_1; RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
D A4G23_03205 rtcB_2; RNA-splicing ligase RtcB K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D A4G23_02432 2',5' RNA ligase family K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
D A4G23_02794 RNA 2'-phosphotransferase K07559 kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]
B tRNA transport factors
C tRNA export factors
D A4G23_01744 putative ABC transporter ATP-binding protein K06020 ettA; energy-dependent translational throttle protein EttA
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D A4G23_01640 leuS; Leucine--tRNA ligase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D A4G23_03201 lysS; Lysine--tRNA ligase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D A4G23_04223 proS; Proline--tRNA ligase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D A4G23_01051 tyrS; Tyrosine--tRNA ligase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D A4G23_03156 trpS_1; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D A4G23_03511 trpS_2; Tryptophan--tRNA ligase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D A4G23_00776 thrS; Threonine--tRNA ligase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D A4G23_01265 ileS; Isoleucine--tRNA ligase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D A4G23_03108 lysX_1; Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D A4G23_00745 alaS_1; Alanine--tRNA ligase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D A4G23_01693 valS; Valine--tRNA ligase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D A4G23_02655 metG_1; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D A4G23_03545 metG_2; Methionine--tRNA ligase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D A4G23_02803 serS; Serine--tRNA ligase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D A4G23_02657 aspS; Aspartate--tRNA ligase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D A4G23_02471 cysS; Cysteine--tRNA ligase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D A4G23_04106 gltX; Glutamate--tRNA ligase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D A4G23_03200 argS_1; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D A4G23_03943 argS_2; Arginine--tRNA ligase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D A4G23_00838 pheS; Phenylalanine--tRNA ligase alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D A4G23_00837 pheT; Phenylalanine--tRNA ligase beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D A4G23_00752 hisS; Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
C Trans-editing factors
D A4G23_02517 dtd; D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D A4G23_01242 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK K03976 ybaK; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D A4G23_02840 tadA; tRNA-specific adenosine deaminase K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
C Methylthiotransferases
D A4G23_04298 miaB; (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
C Methyltransferases
D A4G23_02593 trmB; tRNA (guanine-N(7)-)-methyltransferase K03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]
D A4G23_04154 trmD; tRNA (guanine-N(1)-)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D A4G23_00840 aviRb; 23S rRNA (uridine(2479)-2'-O)-methyltransferase K03437 spoU; RNA methyltransferase, TrmH family
C Psudouridine synthases
D A4G23_03397 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D A4G23_04234 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D A4G23_00916 rluA; Ribosomal large subunit pseudouridine synthase A K06177 rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]
C Thiolation factors
D A4G23_04057 mnmA; tRNA-specific 2-thiouridylase MnmA K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D A4G23_01341 iscS_1; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D A4G23_04054 iscS_2; Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D A4G23_02518 ygfZ; tRNA-modifying protein YgfZ K06980 ygfZ; tRNA-modifying protein YgfZ
C KEOPS/EKC complex
C Other tRNA modification factors
D A4G23_04302 miaA; tRNA dimethylallyltransferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D A4G23_03099 tilS; tRNA(Ile)-lysidine synthase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D A4G23_03426 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D A4G23_03954 ywlC_1; Threonylcarbamoyl-AMP synthase K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D A4G23_03428 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D A4G23_03423 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
B tRNA degradation factors
C A4G23_04251 pnp; Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 17, 2025