+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Streptosporangium roseum

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS E Sros_8815 Polyketide synthase modules and related protein-like protein K12443 ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292] C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type D Sros_6999 Polyketide synthase modules and related protein-like protein K15314 sgcE; enediyne polyketide synthase D Sros_8249 Polyketide synthase modules and related protein-like protein K15314 sgcE; enediyne polyketide synthase B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS E Sros_4153 hypothetical protein K14670 whiEVI; aromatase E Sros_4148 hypothetical protein K14671 whiEVII; cyclase C C7-C14 cyclized polyketide type D Octaketide PKS E Sros_4150 3-oxoacyl-(acyl-carrier-protein) synthase II K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Sros_4151 3-oxoacyl-(acyl-carrier-protein) synthase II K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Sros_4152 conserved hypothetical protein K05553 actI3; minimal PKS acyl carrier protein E Sros_6284 beta-lactamase domain-containing protein K05555 actIV; cyclase [EC:4.-.-.-] D Nonaketide PKS E Sros_4150 3-oxoacyl-(acyl-carrier-protein) synthase II K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Sros_4151 3-oxoacyl-(acyl-carrier-protein) synthase II K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Sros_4152 conserved hypothetical protein K05553 actI3; minimal PKS acyl carrier protein D Decaketide PKS E Sros_4150 3-oxoacyl-(acyl-carrier-protein) synthase II K05551 actI1; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Sros_4151 3-oxoacyl-(acyl-carrier-protein) synthase II K05552 actI2; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235] E Sros_4152 conserved hypothetical protein K05553 actI3; minimal PKS acyl carrier protein B Type III PKS C Plant type C Fungal type C Bacterial type D Sros_5949 3-oxoacyl-(ACP) synthase III K16167 bpsA; alkylresorcinol/alkylpyrone synthase D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D Sros_6555 conserved hypothetical protein K05375 mbtH; MbtH protein D Sros_6841 MbtH domain-containing protein K05375 mbtH; MbtH protein D Sros_6969 conserved hypothetical protein K05375 mbtH; MbtH protein D Sros_5581 conserved hypothetical protein K05375 mbtH; MbtH protein D Sros_2422 conserved hypothetical protein K05375 mbtH; MbtH protein D Sros_3469 conserved hypothetical protein K05375 mbtH; MbtH protein D Sros_2200 conserved hypothetical protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D Sros_3774 (2,3-dihydroxybenzoyl)adenylate synthase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Bacillibactin synthetase D Sros_3774 (2,3-dihydroxybenzoyl)adenylate synthase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase D Sros_3767 pyochelin synthetase F K12240 pchF; L-cysteine---[L-cysteinyl-carrier protein] ligase PchF [EC:6.2.1.69] C Mycobactin synthetase C Vibriobactin synthetase D Sros_3774 (2,3-dihydroxybenzoyl)adenylate synthase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Myxochelin synthetase D Sros_3774 (2,3-dihydroxybenzoyl)adenylate synthase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase D Sros_3774 (2,3-dihydroxybenzoyl)adenylate synthase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] # APolyketide tailoring proteins B Hydrolase C Sros_6998 hypothetical protein K15315 sgcE10; enediyne core biosynthesis thioesterase B Ketoreductase B Oxygenase C Sros_4752 hypothetical protein K14632 actVA6; C-6 monooxygenase C Sros_8715 cytochrome P450-family protein K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C Sros_6983 cytochrome P450-family protein K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C Sros_6973 4-hydroxyphenylacetate 3-monooxygenase oxygenase component K21184 sgcC; two-component FAD-dependent monooxygenase [EC:1.14.14.15 1.14.14.-] C Sros_5100 putative hydrolase K21159 sgcF; epoxide hydrolase C Sros_5218 putative hydrolase K21159 sgcF; epoxide hydrolase C Sros_2973 Microsomal epoxide hydrolase K21159 sgcF; epoxide hydrolase C Sros_0451 Microsomal epoxide hydrolase K21159 sgcF; epoxide hydrolase C Sros_1214 putative hydrolase K21159 sgcF; epoxide hydrolase C Sros_9243 putative hydrolase K21159 sgcF; epoxide hydrolase C Sros_4599 putative hydrolase K21159 sgcF; epoxide hydrolase C Sros_4618 putative epoxide hydrolase K21159 sgcF; epoxide hydrolase C Sros_4149 hypothetical protein K14673 whiEII; putative monooxygenase C Sros_4181 PheA/TfdB family FAD-binding monooxygenase K14672 whiEVIII; putative polyketide hydroxylase C Sros_4156 PheA/TfdB family FAD-binding monooxygenase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C Sros_6986 hydroxyneurosporene-O-methyltransferase K21178 sgcD4; O-methyltransferase [EC:2.1.1.-] C Sros_6962 hydroxyneurosporene-O-methyltransferase K21178 sgcD4; O-methyltransferase [EC:2.1.1.-] C Sros_5950 conserved hypothetical protein K16168 bpsB; methyltransferase B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C Sros_7003 hypothetical protein K21160 sgcE2; enediyne biosynthesis protein E2 C Sros_7002 hypothetical protein K21161 sgcE3; enediyne biosynthesis protein E3 C Sros_8246 hypothetical protein K21161 sgcE3; enediyne biosynthesis protein E3 C Sros_7001 hypothetical protein K21162 sgcE4; enediyne biosynthesis protein E4 C Sros_8247 hypothetical protein K21162 sgcE4; enediyne biosynthesis protein E4 C Sros_7000 hypothetical protein K21163 sgcE5; enediyne biosynthesis protein E5 C Sros_8248 hypothetical protein K21163 sgcE5; enediyne biosynthesis protein E5 C Sros_6996 cytochrome P450 family protein K21164 sgcE7; enediyne biosynthesis protein E7 C Sros_6993 hypothetical protein K21165 sgcE8; enediyne biosynthesis protein E8 C Sros_6992 Choline dehydrogenase and related flavoprotein-like protein K21166 sgcE9; enediyne biosynthesis protein E9 C Sros_6990 wyosine base formation K21167 sgcE11; enediyne biosynthesis protein E11 C Sros_6976 Non-ribosomal peptide synthetase modules and related protein-like protein K21186 sgcC5; condensation enzyme C Sros_6997 flavin reductase-like, FMN-binding protein K21185 sgcE6; flavin reductase # ANonribosomal peptide tailoring proteins B Reductase C Sros_3769 conserved hypothetical protein K12241 pchG; pyochelin biosynthesis protein PchG B Thioesterase C Sros_6554 Oleoyl-(acyl-carrier-protein) hydrolase K12242 pchC; pyochelin biosynthesis protein PchC B Oxygenase B Glycosyltransferase C Sros_5179 glycosyl transferase K16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310] B Aminotransferase B Others C Sros_3487 selenocysteine lyase / isopenicillin N epimerase K04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17] C Sros_6970 4-hydroxyphenylpyruvate dioxygenase K16421 hmaS; 4-hydroxymandelate synthase [EC:1.13.11.46] C Sros_4590 aspartate racemase K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024