+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Serratia rubidaea</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      AXX16_2510 Methyl-directed repair DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
D      AXX16_0811 Methyl-directed repair DNA adenine methylase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
D      AXX16_0047 DNA-cytosine methyltransferase	K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
D      AXX16_2007 hypothetical protein	K18920 hokA; protein HokA 
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
D      AXX16_1891 hypothetical protein	K18843 hicB; antitoxin HicB 
C    YafO-YafN
C    Hha-TomB
D      AXX16_4060 hemolysin expression modulating protein	K05839 hha; haemolysin expression modulating protein 
D      AXX16_4059 hypothetical protein	K19162 tomB; hha toxicity modulator TomB 
C    PspC-PspB
D      AXX16_3012 Phage shock protein C	K03973 pspC; phage shock protein C 
D      AXX16_3013 Phage shock protein B	K03970 pspB; phage shock protein B 
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      AXX16_2299 VapC toxin protein	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      AXX16_2048 VapC toxin protein	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      AXX16_2298 VapB protein (antitoxin to VapC)	K18829 mvpT; antitoxin VapB 
D      AXX16_2049 Virulence-associated protein vagC	K18829 mvpT; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
D      AXX16_0792 VapC toxin protein	K07062 fitB; toxin FitB [EC:3.1.-.-] 
D      AXX16_0793 VapC toxin protein	K21495 fitA; antitoxin FitA 
C    BC_0920-BC_0921
C    Type II TA system related factors
D      AXX16_3781 putative exported protein	K12151 bhsA; multiple stress resistance protein BhsA 
D      AXX16_4383 Cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      AXX16_1006 Rod shape-determining protein MreB	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      AXX16_1153 Topoisomerase IV subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      AXX16_1149 Topoisomerase IV subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      AXX16_1871 Glutamyl-tRNA synthetase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      AXX16_1446 putative membrane protein	K19168 cptA; toxin CptA 
D      AXX16_1445 YgfY	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    AXX16_1194 Cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
C    AXX16_1684 Cysteine desulfurase, IscS subfamily	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023