+F Repair protein KO
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DNA Repair and Recombination Proteins - Shewanella sediminis
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Ssed_2903 Methylated-DNA--(protein)-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Ssed_3688 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Ssed_1219 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Ssed_2038 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
E Ssed_0374 ERCC4 domain protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D Ssed_0419 mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Ssed_2716 MutT/NUDIX family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Ssed_0383 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D Ssed_2903 Methylated-DNA--(protein)-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E Ssed_3688 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E Ssed_2904 transcriptional regulator, AraC family K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E Ssed_1219 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E Ssed_0016 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E Ssed_0117 DNA-formamidopyrimidine glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E Ssed_2038 DNA-(apurinic or apyrimidinic site) lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E Ssed_1668 exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E Ssed_1179 Deoxyribonuclease IV (phage-T(4)-induced) K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E Ssed_0895 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E Ssed_1738 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E Ssed_0096 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E Ssed_4027 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
E Ssed_2046 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
E Ssed_2454 excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
E Ssed_0467 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Ssed_4241 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Ssed_0096 DNA-directed DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E Ssed_1738 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F Ssed_4324 DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F Ssed_4323 DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F Ssed_4294 DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F Ssed_0335 DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F Ssed_2833 transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E Ssed_1299 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E Ssed_0795 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
E Ssed_1131 DNA mismatch repair endonuclease MutH K03573 mutH; DNA mismatch repair protein MutH
D DNA exonucleases
E Ssed_2617 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E Ssed_3125 Exodeoxyribonuclease VII K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E Ssed_3327 exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E Ssed_3146 DNA-directed DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E Ssed_0007 DNA-directed DNA polymerase K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E Ssed_1009 DNA polymerase III chi subunit, HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E Ssed_3481 DNA-directed DNA polymerase K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E Ssed_2647 DNA-directed DNA polymerase K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E Ssed_1752 exonuclease, RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Ssed_1993 DNA-directed DNA polymerase K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Ssed_2322 exonuclease, RNase T and DNA polymerase III K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Ssed_2410 DNA-directed DNA polymerase K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E Ssed_2852 DNA-directed DNA polymerase K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E Ssed_1738 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E Ssed_0467 DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Ssed_4241 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E Ssed_4025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E Ssed_4262 Site-specific DNA-methyltransferase (adenine-specific) K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E Ssed_1936 exodeoxyribonuclease V, beta subunit K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E Ssed_1937 exodeoxyribonuclease V, gamma subunit K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E Ssed_1935 Exodeoxyribonuclease V K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E Ssed_1300 Calcium-transporting ATPase K03553 recA; recombination protein RecA
E Ssed_2033 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Ssed_2034 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Ssed_2032 Crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E Ssed_0534 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E Ssed_0758 single-strand binding protein/primosomal replication protein N K02686 priB; primosomal replication protein N
E Ssed_1564 primosomal replication protein N'', putative K04067 priC; primosomal replication protein N''
E Ssed_2617 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E Ssed_1589 exonuclease SbcC, putative K03546 sbcC; DNA repair protein SbcC/Rad50
E Ssed_1588 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E Ssed_1300 Calcium-transporting ATPase K03553 recA; recombination protein RecA
E Ssed_3370 Methylated-DNA--(protein)-cysteine S-methyltransferase K04485 radA; DNA repair protein RadA/Sms
E Ssed_0008 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E Ssed_0329 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E Ssed_0895 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E Ssed_1150 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E Ssed_2850 recombination protein RecR K06187 recR; recombination protein RecR
E Ssed_1281 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E Ssed_3306 putative exonuclease, RdgC K03554 rdgC; recombination associated protein RdgC
E Ssed_2033 Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E Ssed_2034 Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E Ssed_2032 Crossover junction endodeoxyribonuclease K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E Ssed_1862 type III restriction enzyme, res subunit K19789 radD; DNA repair protein RadD
D Archaeal homologous recombinant proteins
E Ssed_1589 exonuclease SbcC, putative K03546 sbcC; DNA repair protein SbcC/Rad50
E Ssed_1588 nuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F Ssed_2303 DNA topoisomerase (ATP-hydrolyzing) K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F Ssed_0009 DNA topoisomerase (ATP-hydrolyzing) K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F Ssed_2841 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F Ssed_0600 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F Ssed_1544 histone family protein DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F Ssed_0895 single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F Ssed_1150 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F Ssed_2850 recombination protein RecR K06187 recR; recombination protein RecR
F Ssed_1738 DNA ligase (NAD(+)) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F Ssed_4119 transcriptional regulator, fis family K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F Ssed_2596 integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
F Ssed_2297 integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F Ssed_2617 Exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F Ssed_0391 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Ssed_2318 23S rRNA (Gm2251)-methyltransferase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F Ssed_4027 excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
F Ssed_2046 excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
F Ssed_1444 histone family protein nucleoid-structuring protein H-NS K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D Ssed_3422 DNA-directed DNA polymerase K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D Ssed_2171 DNA-directed DNA polymerase K03502 umuC; DNA polymerase V
D Ssed_2172 SOS-response transcriptional repressor LexA -like protein K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D Ssed_1300 Calcium-transporting ATPase K03553 recA; recombination protein RecA
D Ssed_0200 Repressor lexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D Ssed_1281 DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D Ssed_1567 DNA polymerase B region K02336 polB; DNA polymerase II [EC:2.7.7.7]
D Ssed_4025 single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D Ssed_3210 regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D Ssed_4147 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D Ssed_2255 UvrD/REP helicase K03658 helD; DNA helicase IV [EC:5.6.2.4]
D Ssed_1566 helicase C2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D Ssed_2535 helicase C2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D Ssed_0419 mutator MutT protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Ssed_2716 MutT/NUDIX family protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D Ssed_0383 dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D Ssed_2306 Ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D Ssed_2307 Ribonucleoside-diphosphate reductase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 5, 2025