+D
#
Transfer RNA Biogenesis - Sphaerobacter thermophilus
%
!
AEukaryotic type
B 5'processing factors
C Ribonucrease P
B 3'processing and CCA adding factors
C 3'processing factors
D Sthe_1349 Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
C CCA adding factors
D Sthe_2455 polynucleotide adenylyltransferase/metal dependent phosphohydrolase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonuclease complex
C tRNA splicing ligase complex
D Sthe_3251 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
B tRNA transport factors
C tRNA export factors
C tRNA import factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Sthe_2093 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Sthe_1342 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D Sthe_0337 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Sthe_1438 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Sthe_2646 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Sthe_2647 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Sthe_2292 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Sthe_1110 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Sthe_1221 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
C Other AARSs
D Sthe_1558 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Sthe_0466 glycyl-tRNA synthetase K01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]
D Sthe_0456 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Sthe_1627 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Sthe_1593 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Sthe_1612 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Sthe_0476 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Sthe_1674 Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Sthe_1669 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Sthe_1670 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Sthe_1262 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Sthe_3196 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C Trans-editing factors
D Sthe_0709 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Sthe_0316 Threonyl/alanyl tRNA synthetase SAD K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
C AARS associated factors
D Sthe_0786 histidine triad (HIT) protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
B tRNA modification factors
C Deaminases
C Dihydorouridine synthases
C Methylthiotransferase
D Sthe_1020 RNA modification enzyme, MiaB family K06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D Sthe_1294 MiaB-like tRNA modifying enzyme K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]
C Methyltransferases
C Psudouridine synthases
D Sthe_1066 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Sthe_1260 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D Sthe_0396 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Sthe_2643 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Elongator complex
C Elongator related proteins
C Other tRNA modification factors
D Sthe_0417 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Sthe_3264 tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D Sthe_0169 tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D Sthe_1641 glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D Sthe_0838 selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
B tRNA degradation factors
C TRAMP complex
C Rapid tRNA decay (RTD) pathway factors
C Other tRNA degradation factors
#
AProkaryotic type
B 5'processing factors
C Ribonucrease P
D Sthe_0164 ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D Sthe_R0041 rnpB; RNA component of RNaseP K01978 rnpB; RNase P catalytic RNA component
B 3'processing and CCA adding factors
C 3'processing factors
D Sthe_1349 Ribonuclease Z K00784 rnz; ribonuclease Z [EC:3.1.26.11]
D Sthe_0426 ribonuclease PH K00989 rph; ribonuclease PH [EC:2.7.7.56]
C CCA adding factors
D Sthe_2455 polynucleotide adenylyltransferase/metal dependent phosphohydrolase K00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]
B tRNA spricing factors
C tRNA splicing endonucleases
C tRNA splicing ligases
D Sthe_3251 protein of unknown function UPF0027 K14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]
C Other tRNA splicing factors
D Sthe_1898 2'-5' RNA ligase K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]
B tRNA transport factors
C tRNA export factors
B Aminoacyl-tRNA synthetases (AARSs)
C Multi-aminoacyl-tRNA synthetase complex (MSC)
D Sthe_1438 leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D Sthe_1342 prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
C Other AARSs
D Sthe_1262 tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D Sthe_3196 tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D Sthe_0456 threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D Sthe_0337 isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D Sthe_1110 lysyl-tRNA synthetase K04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]
D Sthe_1558 alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D Sthe_1612 valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D Sthe_2646 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Sthe_2647 methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D Sthe_1627 seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D Sthe_1221 aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D Sthe_1593 cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D Sthe_2093 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D Sthe_2292 arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D Sthe_1669 phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D Sthe_1670 phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D Sthe_0476 histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D Sthe_1674 Histidine--tRNA ligase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
C Trans-editing factors
D Sthe_0709 D-tyrosyl-tRNA(Tyr) deacylase K07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]
D Sthe_0316 Threonyl/alanyl tRNA synthetase SAD K07050 AARSD1; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]
B tRNA modification factors
C Deaminases
D Sthe_2022 CMP/dCMP deaminase zinc-binding protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
C Dihydorouridine synthases
C Methylthiotransferases
D Sthe_1020 RNA modification enzyme, MiaB family K06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D Sthe_1294 MiaB-like tRNA modifying enzyme K15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]
C Methyltransferases
D Sthe_3307 Methyltransferase type 11 K15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]
D Sthe_0965 tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D Sthe_0169 tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D Sthe_2424 tRNA guanosine-2'-O-methyltransferase K00556 trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]
D Sthe_1169 tRNA/rRNA methyltransferase (SpoU) K03437 spoU; RNA methyltransferase, TrmH family
C Psudouridine synthases
D Sthe_1066 tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D Sthe_1260 tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
C Thiolation factors
D Sthe_2407 tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D Sthe_1395 HesB/YadR/YfhF-family protein K13628 iscA; iron-sulfur cluster assembly protein
D Sthe_0396 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D Sthe_2643 Cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C KEOPS/EKC complex
C Other tRNA modification factors
D Sthe_1641 glucose-inhibited division protein A K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D Sthe_3264 tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D Sthe_1320 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase K07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]
D Sthe_0321 exsB protein K06920 queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]
D Sthe_3312 6-pyruvoyl tetrahydropterin synthase and hypothetical protein K01737 queD; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]
D Sthe_0029 7-cyano-7-deazaguanine reductase K09457 queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]
D Sthe_0461 domain of unknown function DUF1730 K18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]
D Sthe_0838 selenide, water dikinase K01008 selD; selenide, water dikinase [EC:2.7.9.3]
D Sthe_1196 queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D Sthe_2676 thiamine biosynthesis/tRNA modification protein ThiI K03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]
D Sthe_0775 tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D Sthe_0913 peptidase M22 glycoprotease K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D Sthe_0417 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D Sthe_0915 metalloendopeptidase, glycoprotease family K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D Sthe_0912 protein of unknown function UPF0079 K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
B tRNA degradation factors
C Sthe_1553 Polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: September 26, 2025