+E	Transcription factors	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Transcription Factors - Spirochaeta thermophila DSM 6578</h2>
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A<b>Eukaryotic type</b>
B  Basic leucine zipper (bZIP)
C    AP-1(-like) components, Jun
C    AP-1(-like) components, Fos
C    AP-1(-like) components, Maf
C    AP-1(-like) components, NF-E2
C    AP-1(-like) components, Fungal regulators
C    AP-1(-like) components, CRE-BP/ATF
C    CREB
C    C/EBP-like factors
C    bZIP/PAR
C    Plant bZIP factors
C    ZIP only
B  Basic helix-loop-helix (bHLH)
C    Ubiquitous (class A) factors
C    Myogenic transcription factors
C    Achaete-Scute
C    Tal/Twist/Atonal/Hen, Lymphoid factors
C    Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C    Tal/Twist/Atonal/Hen, HEN
C    Tal/Twist/Atonal/Hen, Mesp
C    Tal/Twist/Atonal/Hen, Atonal
C    Tal/Twist/Atonal/Hen, Pancreatic factors
C    Hairy, Hairy/E(SPL)
C    Hairy, Fungal regulators
C    Factors with PAS domain
C    Yabby
C    INO
C    HLH domain only
B  Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C    Ubiquitous bHLH-ZIP factors
C    Cell cycle controlling factors, Myc
C    Cell cycle controlling factors, Mad/Max
C    Other bHLH-ZIP factors
B  Other basic domains
C    NF-1
C    RF-X
C    AP-2 (bHSH)
B  Zinc finger
C    Cys4 thyroid hormone receptor-like
C    Cys4 hepatocyte nuclear factor 4-like
C    Cys4 estrogen receptor-like
C    Cys4 nerve growth factor IB-like
C    Cys4 Fushi tarazu-F1-like
C    Cys4 germ cell nuclear factor
C    Cys4 Knirps/DAX1-like
C    Cys4 GATA-factors
C    Cys2His2 SP/KLF family and related proteins
C    Cys2His2 GLI-like
C    Cys2His2 Snail
C    Cys2His2 BTB-ZF factors
C    Cys2His2 BED
C    Cys2His2 PRDM
C    Cys2His2 metabolic regulators in fungi
C    Cys2His2 others
C    Cys2HisCys zinc factors
C    Cys3His zinc factors
C    Cys2CysHis zinc factors
C    CXXC CpG-binding proteins
C    Cys6 metabolic regulators in fungi
C    Other zinc fingers
B  Helix-turn-helix
C    Homeo domain ANTP: HOXL
C    Homeo domain ANTP: NKL
C    Homeo domain Paired-related
C    Homeo domain LIM
C    Homeo domain POU
C    Homeo domain SINE
C    Homeo domain ZF
C    Homeo domain CUT
C    Homeo domain PROS
C    Homeo domain TALE
C    Homeo domain other
C    Fork head/winged helix developmental regulators
C    Fork head/winged helix tissue-specific regulators
C    Fork head/winged helix cell cycle-controlling factors, E2F
C    Fork head/winged helix cell cycle-controlling factors, DP
C    Fork head/winged helix other regulators
C    Heat shock factors
C    Tryptophan clusters Myb, Myb-factors
C    Tryptophan clusters Myb, Myb-like factors
C    Tryptophan clusters Ets-type
C    Tryptophan clusters interferon-regulating factors
C    TEA domain
C    ARID
B  beta-Scaffold factors with minor groove contacts
C    RHR (Rel homology region) Rel/Ankyrin
C    RHR (Rel homology region) Ankyrin only
C    RHR (Rel homology region) NF-AT
C    STAT
C    p53
C    MADS-box regulators of differentiation, MEF-2
C    MADS-box regulators of differentiation, Homeotic genes
C    MADS-box regulators of differentiation, Yeast regulators
C    MADS-box responders to external signals
C    SAND domain-containing proteins
C    TATA-binding proteins
C    HMG SOX
C    HMG TCF-1
C    HMG2-related
C    UBF
C    Other HMG box factors
C    Heteromeric CCAAT factors
C    Grainyhead
C    Cold-shock domain factors, DbpA-like
C    Cold-shock domain factors, YB-1/DbpB-like
C    Cold-shock domain factors, FRG Y2-like
C    Runt
C    MYRF
B  Other transcription factors
C    HMGI(Y)
C    NUPR
E        Line #4
C    Pocket domain Rb
C    Pocket domain CBP
C    T-box
C    DMRT
C    LRRFIP
C    TCP
C    AP2/ERF
C    WRKY
C    LOB
C    Copper-fist proteins fungal regulators
C    Others
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A<b>Prokaryotic type</b>
B  Helix-turn-helix
C    AraC family
C    LysR family
D      Spith_1705 transcriptional regulator, LysR family	K02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC 
C    DeoR family
D      Spith_1348 transcriptional regulator, DeoR family	K02436 gatR; DeoR family transcriptional regulator, galactitol utilization operon repressor 
C    LacI family
D      Spith_0080 transcriptional regulator, LacI family	K02529 galR; LacI family transcriptional regulator, galactose operon repressor 
D      Spith_0716 transcriptional regulator, LacI family	K02529 galR; LacI family transcriptional regulator, galactose operon repressor 
D      Spith_0426 transcriptional regulator, LacI family	K02529 galR; LacI family transcriptional regulator, galactose operon repressor 
D      Spith_1522 transcriptional regulator, LacI family	K02529 galR; LacI family transcriptional regulator, galactose operon repressor 
D      Spith_1524 transcriptional regulator, LacI family	K02529 galR; LacI family transcriptional regulator, galactose operon repressor 
D      Spith_1583 transcriptional regulator, LacI family	K02529 galR; LacI family transcriptional regulator, galactose operon repressor 
D      Spith_2100 transcriptional regulator, LacI family	K02529 galR; LacI family transcriptional regulator, galactose operon repressor 
C    GntR family
D      Spith_1892 transcriptional regulator, GntR family with LacI sensor	K02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor 
D      Spith_0633 GntR domain protein	K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex 
C    TetR/AcrR family
D      Spith_2001 regulatory protein TetR	K09017 rutR; TetR/AcrR family transcriptional regulator 
C    Lrp/AsnC family
C    LuxR family
C    MarR family
C    MerR family
C    Fur family
D      Spith_1930 ferric uptake regulator, Fur family	K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator 
C    IclR family
C    CRP/FNR family
D      Spith_0172 putative transcriptional regulator, Crp/Fnr family	K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein 
D      Spith_1430 putative transcriptional regulator, Crp/Fnr family	K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein 
D      Spith_2063 transcriptional regulator, Crp/Fnr family	K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator 
C    Rrf2 family
D      Spith_0885 transcriptional regulator, BadM/Rrf2 family	K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor 
D      Spith_0865 transcriptional regulator, BadM/Rrf2 family	K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor 
C    ArsR family
D      Spith_1637 regulatory protein ArsR	K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor 
C    XRE family
C    PadR family
D      Spith_0622 transcriptional regulator, PadR-like family	K10947 K10947; PadR family transcriptional regulator 
C    Other families
D      Spith_0643 iron (metal) dependent repressor, DtxR family	K03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator 
D      Spith_0785 biotin/acetyl-CoA-carboxylase ligase	K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] 
D      Spith_2049 biotin/acetyl-CoA-carboxylase ligase	K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15] 
D      Spith_1922 Trp repressor	K03720 trpR; TrpR family transcriptional regulator, trp operon repressor 
D      Spith_0836 transcriptional regulator, NifA, Fis Family	K02584 nifA; Nif-specific regulatory protein 
D      Spith_1124 transcriptional regulator, NifA subfamily, Fis Family	K02584 nifA; Nif-specific regulatory protein 
D      Spith_0139 Redox-sensing transcriptional repressor rex	K01926 rex; redox-sensing transcriptional repressor 
D      Spith_0798 Redox-sensing transcriptional repressor rex	K01926 rex; redox-sensing transcriptional repressor 
D      Spith_1512 Redox-sensing transcriptional repressor rex	K01926 rex; redox-sensing transcriptional repressor 
B  Ribbon-helix-helix
C    CopG family
C    Other families
B  Other transcription factors
C    BglG family
C    Others
D      Spith_1442 ParB domain protein nuclease	K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein 
D      Spith_2291 parB-like partition protein	K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein 
D      Spith_1943 transcriptional regulator, CarD family	K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription 
D      Spith_2052 arginine repressor, ArgR	K03402 argR; transcriptional regulator of arginine metabolism 
D      Spith_1732 transcriptional regulator, TraR/DksA family	K06204 dksA; RNA polymerase-binding transcription factor 
D      Spith_1463 Transcriptional repressor nrdR	K07738 nrdR; transcriptional repressor NrdR 
D      Spith_0916 Protein mraZ	K03925 mraZ; transcriptional regulator MraZ 
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#Last updated: May 8, 2024
#<br>Classification taken and modified from <a href="http://www.gene-regulation.com/pub/databases.html#transfac">TRANSFAC 7.0</a>