+D Transcription factors KO
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Transcription Factors - Salmonella enterica subsp. enterica serovar Typhi Ty2
%
!
AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
C AP-1(-like) components, Fos
C AP-1(-like) components, Maf
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
C CREB
C C/EBP-like factors
C bZIP/PAR
C Plant bZIP factors
C ZIP only
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
C Myogenic transcription factors
C Achaete-Scute
C Tal/Twist/Atonal/Hen, Lymphoid factors
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C Tal/Twist/Atonal/Hen, HEN
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
C Hairy, Fungal regulators
C Factors with PAS domain
C Yabby
C INO
C HLH domain only
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
C RF-X
C AP-2 (bHSH)
B Zinc finger
C Cys4 thyroid hormone receptor-like
C Cys4 hepatocyte nuclear factor 4-like
C Cys4 estrogen receptor-like
C Cys4 nerve growth factor IB-like
C Cys4 Fushi tarazu-F1-like
C Cys4 germ cell nuclear factor
C Cys4 Knirps/DAX1-like
C Cys4 GATA-factors
C Cys2His2 SP/KLF family and related proteins
C Cys2His2 GLI-like
C Cys2His2 Snail
C Cys2His2 BTB-ZF factors
C Cys2His2 BED
C Cys2His2 PRDM
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
C Cys2HisCys zinc factors
C Cys3His zinc factors
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D t0886 dcm; DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
B Helix-turn-helix
C Homeo domain ANTP: HOXL
C Homeo domain ANTP: NKL
C Homeo domain Paired-related
C Homeo domain LIM
C Homeo domain POU
C Homeo domain SINE
C Homeo domain ZF
C Homeo domain CUT
C Homeo domain PROS
C Homeo domain TALE
C Homeo domain other
C Fork head/winged helix developmental regulators
C Fork head/winged helix tissue-specific regulators
C Fork head/winged helix cell cycle-controlling factors, E2F
C Fork head/winged helix cell cycle-controlling factors, DP
C Fork head/winged helix other regulators
C Stork head/winged helix factors
C Heat shock factors
C Tryptophan clusters Myb, Myb-factors
C Tryptophan clusters Myb, Myb-like factors
C Tryptophan clusters Ets-type
C Tryptophan clusters interferon-regulating factors
C TEA domain
C ARID
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
C RHR (Rel homology region) Ankyrin only
C RHR (Rel homology region) NF-AT
C STAT
C p53
C MADS-box regulators of differentiation, MEF-2
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
C SAND domain-containing proteins
C TATA-binding proteins
C HMG SOX
C HMG TCF-1
C HMG TOX
C HMG2-related
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
C Grainyhead
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
C Cold-shock domain factors, FRG Y2-like
C Runt
C MYRF
B Other transcription factors
C HMGI(Y)
C NUPR
C Pocket domain Rb
C Pocket domain CBP
C T-box
C DMRT
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
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AProkaryotic type
B Helix-turn-helix
C AraC family
D t0108 araC; arabinose operon regulatory protein K02099 araC; AraC family transcriptional regulator, arabinose operon regulatory protein
D t1811 hpaA; 4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein K02508 hpaA; AraC family transcriptional regulator, 4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein
D t3570 rhaR; L-rhamnose operon transcriptional activator K02854 rhaR; AraC family transcriptional regulator, L-rhamnose operon transcriptional activator RhaR
D t3571 rhaS; L-rhamnose operon regulatory protein K02855 rhaS; AraC family transcriptional regulator, L-rhamnose operon regulatory protein RhaS
D t1194 celD; putative cel operon repressor K03490 chbR; AraC family transcriptional regulator, dual regulator of chb operon
D t4202 adiY; putative AraC family regulatory protein K03755 adiY; AraC family transcriptional regulator, transcriptional activator of adiA
D t0404 yfeG; ethanolamine operon transcriptional regulator K04033 eutR; AraC family transcriptional regulator, ethanolamine operon transcriptional activator
D t4171 soxS; regulatory protein SoxS K13631 soxS; AraC family transcriptional regulator, mar-sox-rob regulon activator
D t1440 marA; multiple antibiotic resistance protein MarA K13632 marA; AraC family transcriptional regulator, mar-sox-rob regulon activator
D t4625 rob; right origin-binding protein K05804 rob; AraC family transcriptional regulator, mar-sox-rob regulon activator
D t2287 ramA; transcriptional activator RamA K18325 ramA; AraC family of transcriptional regulator, multidrug resistance transcriptional activator
D t2299 ykgD; hypothetical araC-family transcriptional regulator K21746 rclR; AraC family transcriptional regulator, reactive chlorine species (RCS)-specific activator of rcl operon
D t4204 melR; melibiose operon regulatory protein K23237 melR; AraC family transcriptional regulator, melibiose operon regulatory protein
D t1159 putative transcriptional regulator K25495 nimR; AraC family transcriptional regulator, regulator of nimT
D t0838 pocR; pdu/cob regulatory protein PocR K27259 pocR; AraC family transcriptional regulator, pdu and cob operon regulator
D t3096 possible AraC-family transcriptional regulator K13652 K13652; AraC family transcriptional regulator
D t0599 ada; ADA regulatory protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
C LysR family
D t2890 gcvA; regulatory protein of glycine cleavage pathway K03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator
D t3390 ilvY; LysR-family regulatory protein for ilvC expression K02521 ilvY; LysR family transcriptional regulator, positive regulator for ilvC
D t3333 metR; trans-activator of metE and metH K03576 metR; LysR family transcriptional regulator, regulator for metE and metH
D t0042 nhaR; transcriptional activator protein NhaR K03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA
D t3500 oxyR; hydrogen peroxide-inducible regulon activator K04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator
D t2982 iciA; chromosome intitiation inhibitor K05596 argP; LysR family transcriptional regulator, arginine and lysine transport system/DNA replication regulator
D t0119 leuO; probable activator protein in leuABCD operon K05798 leuO; LysR family transcriptional regulator, transcriptional activator for leuABCD operon
D t3165 tdcA; TDC operon transcriptional activator K07592 tdcA; LysR family transcriptional regulator, tdc operon transcriptional activator
D t2346 hypothetical lysR-family transcriptional regulator K10972 allS; LysR family transcriptional regulator, transcriptional activator of the allD operon
D t1626 cysB; cys regulon transcriptional activator K13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator
D t3717 dsdC; D-serine deaminase activator K13636 dsdC; LysR family transcriptional regulator, D-serine deaminase activator
D t2183 lysR-family transcriptional regulator K13794 tcuR; LysR family transcriptional regulator, regulatory protein for tcuABC
D t1581 putative transcriptional regulator K18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC
D t4561 probable transcriptional activator K21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT
D t3282 probable LysR-family transcriptional regulator K21698 aaeR; LysR family transcriptional regulator, transcriptional activator for aaeXAB operon
D t3449 possible LysR-family transcriptional regulatory protein K23773 hdfR; LysR family transcriptional regulator, flagellar master operon regulator
C DeoR family
D t2032 deoR; deoxyribose operon repressor K11534 deoR; DeoR family transcriptional regulator, deoxyribose operon repressor
D t3724 putative DeoR-family transcriptional regulator K11534 deoR; DeoR family transcriptional regulator, deoxyribose operon repressor
D t3990 glpR; glycerol-3-phosphate regulon repressor K02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor
D t3182 gatR; galactitol utilization operon repressor K02436 gatR; DeoR family transcriptional regulator, galactitol utilization operon repressor
D t2887 fucR; l-fucose operon activator K02430 fucR; DeoR family transcriptional regulator, L-fucose operon activator
D t2739 srlR; glucitol operon repressor K02468 srlR; DeoR family transcriptional regulator, glucitol operon repressor
D t4432 yjfQ; probable transcriptional regulator K03477 ulaR; DeoR family transcriptional regulator, ulaG and ulaABCDEF operon transcriptional repressor
D t3596 yihW; putative DeoR-family transcriptional regulator K27243 csqR; DeoR family transcriptional regulator, sulfoquinovose operon repressor
C LacI family
D t0664 galS; mgl repressor and galactose ultrainduction factor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D t2921 galR; galactose operon repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D t3633 rbsR; ribose operon repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D t3857 xylR; xylose operon regulatory protein K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D t3524 cytR; transcriptional repressor K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG
D t0122 fruR; fructose repressor K03435 fruR1; LacI family transcriptional regulator, fructose operon transcriptional repressor
D t4490 treR; trehalose operon repressor K03485 treR; LacI family transcriptional regulator, trehalose operon repressor
D t1298 purR; purine nucleotide synthesis repressor K03604 purR; LacI family transcriptional regulator, purine nucleotide synthesis repressor
D t3823 putative lacI family transcriptional regulator K06145 gntR; LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor
D t3978 gntR; gluconate utilization operon repressor K06145 gntR; LacI family transcriptional regulator, gluconate utilization system Gnt-I transcriptional repressor
D t4515 regulatory protein K06146 idnR; LacI family transcriptional regulator, gluconate utilization system Gnt-II transcriptional activator
C GntR family
D t2098 hutC; histidine utilization repressor K05836 hutC; GntR family transcriptional regulator, histidine utilization repressor
D t3915 gntR family regulatory protein K03710 K03710; GntR family transcriptional regulator
D t1072 fadR; fatty acid-fatty acyl responsive DNA-binding protein K03603 fadR; GntR family transcriptional regulator, negative regulator for fad regulon and positive regulator of fabA
D t0157 pdhR; pyruvate dehydrogenase complex repressor K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
D t4556 uxuR; uxu operon transcriptional regulator K13637 uxuR; GntR family transcriptional regulator, uxu operon transcriptional repressor
D t3826 lctR; putative L-lactate dehydrogenase operon regulator K14348 lldR; GntR family transcriptional regulator, L-lactate dehydrogenase operon regulator
D t3257 putative GntR-family transcriptional regulator K22104 nanR; GntR family transcriptional regulator, sialic acid-inducible nan operon repressor
D t3512 putative GntR-family regulatory protein K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D t1498 putative regulatory protein K13654 mcbR; GntR family transcriptional regulator, colanic acid and biofilm gene transcriptional regulator
D t2689 ygaE; putative transcriptional regulator K15735 csiR; GntR family transcriptional regulator, carbon starvation induced regulator
D t1431 putative regulatory protein K22293 rspR; GntR family transcriptional regulator, rspAB operon transcriptional repressor
C TetR/AcrR family
D t2383 acrR; potential acrAB operon repressor K03577 acrR; TetR/AcrR family transcriptional regulator, acrAB operon repressor
D t3786 ttk; putative TetR-family transcriptional regulator K05501 slmA; TetR/AcrR family transcriptional regulator
D t1799 putative transcriptional regulator K09017 rutR; TetR/AcrR family transcriptional regulator
D t1305 putative TetR-family transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D t1578 putative transcriptional regulator K19335 bdcR; TetR/AcrR family transcriptional regulator, repressor for divergent bdcA
D t1707 putative TetR-family regulatory protein K22041 comR; TetR/AcrR family transcriptional regulator, copper-responsive repressor
D t3498 yijC; possible TetR-family trancriptional regulatory protein K22105 fabR; TetR/AcrR family transcriptional regulator, fatty acid biosynthesis regulator
D t2069 ybiH; hypothetical tetR-family transcriptional regulator K23777 cecR; TetR/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity
D t2027 putative TetR-family transcriptional regulator K23778 rcdA; TetR/AcrR family transcriptional regulator, regulator of biofilm formation and stress response
C Lrp/AsnC family
D t3643 asnC; regulatory protein K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D t1933 putative transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D t1975 lrp; leucine-responsive regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D t2400 ybaO; hypothetical transcriptional regulator K05800 decR; Lrp/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator
C LuxR family
D t0926 sdiA; cell-division regulatory protein K07782 sdiA; LuxR family transcriptional regulator, quorum-sensing system regulator SdiA
D t0895 rcsA; colanic acid capsullar biosynthesis activation protein A K07781 rcsA; LuxR family transcriptional regulator, capsular biosynthesis positive transcription factor
D t1778 csgD; putative regulatory protein K04333 csgD; LuxR family transcriptional regulator, csgAB operon transcriptional regulatory protein
D t4591 conserved hypothetical regulatory protein K22650 bglJ; LuxR family transcriptional regulator, regulator of transport and utilization of aryl beta-glucosides
D t3991 malT; MalT regulatory protein K03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein
C MarR family
D t1441 marR; multiple antibiotic resistance protein MarR K03712 marR; MarR family transcriptional regulator, multiple antibiotic resistance protein MarR
D t1312 slyA; transcriptional regulator K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
D t2710 emrR; putative transcriptional regulator K15974 emrR; MarR family transcriptional regulator, negative regulator of the multidrug operon emrRAB
D t2821 slyA; putative regulatory protein K22489 hosA; MarR family transcriptional regulator, temperature-dependent positive regulator of motility
C MerR family
D t2361 cueR; copper efflux regulator K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D t4093 zntR; putative Zn(II)-responsive regulator K13638 zntR; MerR family transcriptional regulator, Zn(II)-responsive regulator of zntA
D t4172 soxR; SoxR protein K13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR
D t0695 yehV; putative transcriptional regulator K21089 mlrA; MerR family transcriptional regulator, activator of the csg genes
C Fur family
D t2182 fur; ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D t4147 zur; zinc uptake regulation protein K09823 zur; Fur family transcriptional regulator, zinc uptake regulator
C IclR family
D t4114 iclR; acetate operon repressor K13641 iclR; IclR family transcriptional regulator, acetate operon repressor
D t2344 allR; negative regulator of allantoin and glyoxylate utilization operons K10973 allR; IclR family transcriptional regulator, negative regulator of allantoin and glyoxylate utilization operons
D t1036 kdgR; transcriptional regulator KdgR K19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor
D t3852 yiaJ; putative transcriptional regulator K21602 yiaJ; IclR family transcriptional regulator, carbohydrate utilization repressor
C CRP/FNR family
D t4039 crp; cyclic AMP receptor protein,catabolite gene activator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D t1564 fnr; fumarate and nitrate reduction regulatory protein K01420 fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein
D t3387 hypothetical protein K21563 dnr; CRP/FNR family transcriptional regulator, dissimilatory nitrate respiration regulator
C Rrf2 family
D t0312 yfhP; conserved hypothetical protein K13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor
D t4418 yjeB; conserved hypothetical protein K13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor
C ArsR family
C XRE family
D t1514 putative DNA-binding protein K23779 sutR; XRE family transcriptional regulator, regulator of sulfur utilization
C PadR family
C Other families
D t2052 transcriptional regulator K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
D t0990 hexR; putative hex-regulon repressor K19337 hexR; RpiR family transcriptional regulator, carbohydrate utilization regulator
D t3488 birA; biotin operon repressor K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D t3300 fis; Fis DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
D t4622 trpR; probable trp operon repressor K03720 trpR; TrpR family transcriptional regulator, trp operon repressor
D t2497 prpR; propionate catabolism operon regulatory protein K02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein
D t3223 nlp; Ner-like regulatory protein K07724 ner; Ner family transcriptional regulator
D t4364 cII; transcriptional regulatory protein K07724 ner; Ner family transcriptional regulator
D t0113 yabN; putative ABC transporter periplasmic solute binding protein K11925 sgrR; SgrR family transcriptional regulator
D t3663 conserved hypothetical protein K11925 sgrR; SgrR family transcriptional regulator
D t4619 nadR; conserved hypothetical transcriptional regulator K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]
D t3591 ygjM; conserved hypothetical protein K18831 higA; HTH-type transcriptional regulator / antitoxin HigA
D t2741 ygaA; putative sigma-54-dependent transriptional regulator K12266 norR; anaerobic nitric oxide reductase transcription regulator
D t2761 fhlA; transcriptional activator of the formate hydrogenlyase system K15836 fhlA; formate hydrogenlyase transcriptional activator
D t0211 yaeG; conserved hypothetical protein K02647 cdaR; carbohydrate diacid regulator
D t0503 putative transcriptional regulator K06714 rocR; arginine utilization regulatory protein
D t2108 modE; putative molybdenum transport protein ModE K02019 modE; molybdate transport system regulatory protein
D t3740 putative DNA-binding protein K07726 K07726; putative transcriptional regulator
D t3871 putative DNA-binding protein K07726 K07726; putative transcriptional regulator
B Ribbon-helix-helix
C CopG family
D t3938 nikR; nickel responsive regulator K07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator
C Other families
D t3519 metJ; repressor of the methionine regulon K03764 metJ; MetJ family transcriptional regulator, methionine regulon repressor
D t1797 putA; proline dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D t4483 relB; RelB protein K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB
B Other transcription factors
C BglG family
C Others
D t2933 conserved hypothetical protein K23240 rcnR; FrmR/RcnR family transcriptional regulator, repressor of rcnA expression
D t2414 bolA; BolA protein K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D t3320 rfaH; transcriptional activator K05785 rfaH; transcriptional antiterminator RfaH
D t3275 argR; arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D t2193 nagC; N-acetylglucosamine repressor K02565 nagC; N-acetylglucosamine repressor
D t1409 putative regulatory protein K15545 mlc; transcriptional regulator of PTS gene
D t3832 mtlR; mannitol operon repressor K02562 mtlR; mannitol operon repressor
D t1588 tyrR; transcriptional regulatory protein TyrR K03721 tyrR; transcriptional regulator of aroF, aroG, tyrA and aromatic amino acid transport
D t0299 cadC; transcriptional activator CadC K03765 cadC; transcriptional activator of cad operon
D t2778 iagA; invasion protein regulator K22486 hilA; transcriptional regulator HilA, main transcriptional regulator of SPI1
D t0369 gcvR; glycine cleavage system transcriptional repressor K03567 gcvR; glycine cleavage system transcriptional repressor
D t1596 pspF; psp operon transcriptional activator PspF K03974 pspF; psp operon transcriptional activator
D t1593 pspC; phage shock protein C K03973 pspC; phage shock protein C
D t3545 ydeW; putative regulatory protein K11531 lsrR; lsr operon transcriptional repressor
D t2251 rnk; regulator of nucleoside diphosphate kinase K06140 rnk; regulator of nucleoside diphosphate kinase
D t2651 hypothetical protein K07733 alpA; prophage regulatory protein
D t4525 phage DNA binding protein K07733 alpA; prophage regulatory protein
D t3008 conserved hypothetical protein K07735 algH; putative transcriptional regulator
D t0069 caiF; transcriptional activator CaiF K08277 caiF; transcriptional activator CaiF
D t0194 dksA; dosage-dependent dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D t2448 ybaD; hypothetical protein K07738 nrdR; transcriptional repressor NrdR
D t2531 crl; curlin genes transcriptional activator K11926 crl; sigma factor-binding protein Crl
D t0123 yabB; conserved hypothetical protein K03925 mraZ; transcriptional regulator MraZ
D t2313 fimY; fimbriae Y protein K08088 fimY; fimbrial regulator
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 21, 2025
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Classification taken and modified from TRANSFAC 7.0